Proteolytic enhancement of rotavirus infectivity: molecular mechanisms.

PubWeight™: 4.87‹?› | Rank: Top 1%

🔗 View Article (PMC 171321)

Published in J Virol on September 01, 1981

Authors

M K Estes, D Y Graham, B B Mason

Articles citing this

(truncated to the top 100)

Rotavirus gene structure and function. Microbiol Rev (1989) 6.95

Production and preliminary characterization of monoclonal antibodies directed at two surface proteins of rhesus rotavirus. J Virol (1983) 5.44

The rhesus rotavirus gene encoding protein VP3: location of amino acids involved in homologous and heterologous rotavirus neutralization and identification of a putative fusion region. Proc Natl Acad Sci U S A (1988) 4.23

Sequence of the fourth gene of human rotaviruses recovered from asymptomatic or symptomatic infections. J Virol (1988) 3.20

Molecular basis of rotavirus virulence: role of gene segment 4. J Virol (1986) 3.08

Neutralizing monoclonal antibodies to human rotavirus and indications of antigenic drift among strains from neonates. J Virol (1985) 2.81

Infectious rotavirus enters cells by direct cell membrane penetration, not by endocytosis. J Virol (1988) 2.72

Human viral gastroenteritis. Microbiol Rev (1984) 2.70

Identification, synthesis, and modifications of simian rotavirus SA11 polypeptides in infected cells. J Virol (1982) 2.67

Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. Proc Natl Acad Sci U S A (2009) 2.65

Cross-reactive neutralization epitopes on VP3 of human rotavirus: analysis with monoclonal antibodies and antigenic variants. J Virol (1987) 2.51

Purification and characterization of bovine rotavirus cores. J Virol (1982) 2.43

Conservation of the fourth gene among rotaviruses recovered from asymptomatic newborn infants and its possible role in attenuation. J Virol (1986) 2.42

The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site. EMBO J (2002) 2.41

Expression of rotavirus VP2 produces empty corelike particles. J Virol (1991) 2.38

Conservation of amino acid sequence of VP8 and cleavage region of 84-kDa outer capsid protein among rotaviruses recovered from asymptomatic neonatal infection. Proc Natl Acad Sci U S A (1986) 2.37

RNA-binding proteins of bovine rotavirus. J Virol (1986) 2.26

Functional and topographical analyses of epitopes on the hemagglutinin (VP4) of the simian rotavirus SA11. J Virol (1988) 2.08

Antibodies to the trypsin cleavage peptide VP8 neutralize rotavirus by inhibiting binding of virions to target cells in culture. J Virol (1991) 1.99

Biochemical mapping of the simian rotavirus SA11 genome. J Virol (1983) 1.88

The rhesus rotavirus outer capsid protein VP4 functions as a hemagglutinin and is antigenically conserved when expressed by a baculovirus recombinant. J Virol (1989) 1.80

The nonstructural glycoprotein of rotavirus affects intracellular calcium levels. J Virol (1994) 1.75

Temporal synthesis of proteins and RNAs during human astrovirus infection of cultured cells. J Virol (1991) 1.73

Integrins alpha2beta1 and alpha4beta1 can mediate SA11 rotavirus attachment and entry into cells. J Virol (2000) 1.72

Complete nucleotide sequence of the gene encoding VP4 of a human rotavirus (strain K8) which has unique VP4 neutralization epitopes. J Virol (1989) 1.71

Trypsin cleavage stabilizes the rotavirus VP4 spike. J Virol (2001) 1.68

Trypsin activation pathway of rotavirus infectivity. J Virol (1996) 1.63

Effects of tunicamycin on rotavirus morphogenesis and infectivity. J Virol (1983) 1.61

Phenotypes of rotavirus reassortants depend upon the recipient genetic background. Proc Natl Acad Sci U S A (1989) 1.58

Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to the heterotypic neutralization domain of VP7 and the VP8 fragment of VP4. J Clin Microbiol (1989) 1.58

Specific interactions between rotavirus outer capsid proteins VP4 and VP7 determine expression of a cross-reactive, neutralizing VP4-specific epitope. J Virol (1992) 1.53

Binding to sialic acids is not an essential step for the entry of animal rotaviruses to epithelial cells in culture. J Virol (1993) 1.50

Rotavirus architecture at subnanometer resolution. J Virol (2008) 1.48

Serotype-specific epitope(s) present on the VP8 subunit of rotavirus VP4 protein. J Virol (1991) 1.47

Rotavirus capsid protein VP5* permeabilizes membranes. J Virol (1999) 1.42

Initial interaction of rotavirus strains with N-acetylneuraminic (sialic) acid residues on the cell surface correlates with VP4 genotype, not species of origin. J Virol (2002) 1.42

Selective membrane permeabilization by the rotavirus VP5* protein is abrogated by mutations in an internal hydrophobic domain. J Virol (2000) 1.40

Molecular and antigenic characterization of porcine rotavirus YM, a possible new rotavirus serotype. J Virol (1988) 1.38

Immunization with baculovirus-expressed VP4 protein passively protects against simian and murine rotavirus challenge. J Virol (1990) 1.37

Localization of rotavirus VP4 neutralization epitopes involved in antibody-induced conformational changes of virus structure. J Virol (1994) 1.35

Two forms of VP7 are involved in assembly of SA11 rotavirus in endoplasmic reticulum. J Virol (1988) 1.34

Protease inhibitors suppress the in vitro and in vivo replication of rotavirus. J Clin Invest (1988) 1.33

Proteolysis of monomeric recombinant rotavirus VP4 yields an oligomeric VP5* core. J Virol (2001) 1.33

Rotaviruses induce an early membrane permeabilization of MA104 cells and do not require a low intracellular Ca2+ concentration to initiate their replication cycle. J Virol (1997) 1.32

Structural insights into the coupling of virion assembly and rotavirus replication. Nat Rev Microbiol (2012) 1.30

Rotavirus RNA replication: VP2, but not VP6, is necessary for viral replicase activity. J Virol (1990) 1.29

Role of sialic acids in rotavirus infection. Glycoconj J (2006) 1.28

Cleavage of rhesus rotavirus VP4 after arginine 247 is essential for rotavirus-like particle-induced fusion from without. J Virol (1998) 1.27

Stem cell-derived human intestinal organoids as an infection model for rotaviruses. MBio (2012) 1.27

Extramucosal spread and development of hepatitis in immunodeficient and normal mice infected with rhesus rotavirus. J Virol (1990) 1.27

The amino-terminal half of rotavirus SA114fM VP4 protein contains a hemagglutination domain and primes for neutralizing antibodies to the virus. J Virol (1991) 1.25

Rotavirus spike protein VP4 is present at the plasma membrane and is associated with microtubules in infected cells. J Virol (2000) 1.22

Culturing, storage, and quantification of rotaviruses. Curr Protoc Microbiol (2009) 1.22

Neutralization epitopes on rotavirus SA11 4fM outer capsid proteins. J Virol (1990) 1.20

DNA amplification-restricted transcription-translation: rapid analysis of rhesus rotavirus neutralization sites. Proc Natl Acad Sci U S A (1990) 1.20

Assembly of highly infectious rotavirus particles recoated with recombinant outer capsid proteins. J Virol (2006) 1.20

Serial propagation of porcine group C rotavirus (pararotavirus) in primary porcine kidney cell cultures. J Clin Microbiol (1987) 1.20

Rotavirus interaction with isolated membrane vesicles. J Virol (1994) 1.18

The effects of midgut serine proteases on dengue virus type 2 infectivity of Aedes aegypti. Am J Trop Med Hyg (2008) 1.17

Bluetongue virus: dissection of the polymerase complex. J Gen Virol (2008) 1.17

High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain. J Virol (2006) 1.16

VP4 monotype specificities among porcine rotavirus strains of the same VP4 serotype. J Virol (1991) 1.16

The VP5 domain of VP4 can mediate attachment of rotaviruses to cells. J Virol (2000) 1.16

Requirement for vacuolar H+ -ATPase activity and Ca2+ gradient during entry of rotavirus into MA104 cells. J Virol (2002) 1.14

Addition of exogenous protease facilitates reovirus infection in many restrictive cells. J Virol (2002) 1.13

A rotavirus spike protein conformational intermediate binds lipid bilayers. J Virol (2009) 1.10

Trypsin-induced structural transformation in aquareovirus. J Virol (2000) 1.10

Rotavirus-induced fusion from without in tissue culture cells. J Virol (1995) 1.10

Rotavirus YM gene 4: analysis of its deduced amino acid sequence and prediction of the secondary structure of the VP4 protein. J Virol (1991) 1.09

NS35 and not vp7 is the soluble rotavirus protein which binds to target cells. J Virol (1990) 1.08

Virus-like particle-induced fusion from without in tissue culture cells: role of outer-layer proteins VP4 and VP7. J Virol (1997) 1.07

Alternative intermolecular contacts underlie the rotavirus VP5* two- to three-fold rearrangement. EMBO J (2006) 1.06

Serial propagation of porcine group C rotavirus (pararotavirus) in a continuous cell line and characterization of the passaged virus. J Clin Microbiol (1988) 1.04

VP5* rearranges when rotavirus uncoats. J Virol (2009) 1.04

Rotavirus spike structure and polypeptide composition. J Virol (1991) 1.03

Identification of a type 1 peroxisomal targeting signal in a viral protein and demonstration of its targeting to the organelle. J Virol (2002) 1.01

Rhesus rotavirus entry into a polarized epithelium is endocytosis dependent and involves sequential VP4 conformational changes. J Virol (2010) 1.00

Geometric mismatches within the concentric layers of rotavirus particles: a potential regulatory switch of viral particle transcription activity. J Virol (2008) 1.00

pH-induced conformational change of the rotavirus VP4 spike: implications for cell entry and antibody neutralization. J Virol (2005) 0.99

Location of intrachain disulfide bonds in the VP5* and VP8* trypsin cleavage fragments of the rhesus rotavirus spike protein VP4. J Virol (1993) 0.99

Attachment and growth of human rotaviruses RV-3 and S12/85 in Caco-2 cells depend on VP4. J Virol (1998) 0.98

Innate host barriers to viral trafficking and population diversity: lessons learned from poliovirus. Adv Virus Res (2010) 0.96

Synthesis of plus- and minus-strand RNA in rotavirus-infected cells. J Virol (1987) 0.96

Effect of mutations in VP5 hydrophobic loops on rotavirus cell entry. J Virol (2010) 0.94

Molecular characterization of a rotaviruslike virus isolated from striped bass (Morone saxatilis). J Virol (1990) 0.94

Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit. J Virol (2003) 0.93

Effects of environmental and dietary factors on human rotavirus infection in gnotobiotic piglets. Infect Immun (1984) 0.92

Rotavirus genome segment 4 determines viral replication phenotype in cultured liver cells (HepG2). J Virol (1990) 0.92

Rotavirus structural proteins and dsRNA are required for the human primary plasmacytoid dendritic cell IFNalpha response. PLoS Pathog (2010) 0.92

Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences. J Virol (2004) 0.91

Viruses and cells with mutations affecting viral entry are selected during persistent rotavirus infections of MA104 cells. J Virol (1998) 0.91

The spike protein VP4 defines the endocytic pathway used by rotavirus to enter MA104 cells. J Virol (2012) 0.91

A synthetic peptide corresponding to the cleavage region of VP3 from rotavirus SA11 induces neutralizing antibodies. J Virol (1988) 0.90

Crystal structure of enteric adenovirus serotype 41 short fiber head. J Virol (2005) 0.89

Discrete domains within the rotavirus VP5* direct peripheral membrane association and membrane permeability. J Virol (2004) 0.89

Viral determinants of rotavirus pathogenicity in pigs: production of reassortants by asynchronous coinfection. J Virol (1997) 0.89

Rotaviruses reach late endosomes and require the cation-dependent mannose-6-phosphate receptor and the activity of cathepsin proteases to enter the cell. J Virol (2014) 0.88

Human rotavirus K8 strain represents a new VP4 serotype. J Virol (1993) 0.87

Priming for rotavirus neutralizing antibodies by a VP4 protein-derived synthetic peptide. J Virol (1989) 0.87

Molecular basis of age-dependent gastric inactivation of rhesus rotavirus in the mouse. J Clin Invest (1992) 0.87

Articles cited by this

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51

The role of viral glycoproteins in adsorption, penetration, and pathogenicity of viruses. Rev Infect Dis (1980) 4.61

Rescue of noncultivatable human rotavirus by gene reassortment during mixed infection with ts mutants of a cultivatable bovine rotavirus. Proc Natl Acad Sci U S A (1981) 4.47

In vitro transcription and translation of simian rotavirus SA11 gene products. J Virol (1980) 4.40

Biochemical and biophysical characteristics of diarrhea viruses of human and calf origin. J Virol (1975) 4.06

Activation of rotavirus RNA polymerase by calcium chelation. Arch Virol (1979) 3.44

Structural polypeptides of simian rotavirus SA11 and the effect of trypsin. J Virol (1981) 3.27

Coding assignments of double-stranded RNA segments of SA 11 rotavirus established by in vitro translation. J Virol (1980) 3.10

Rotavirus isolation and cultivation in the presence of trypsin. J Clin Microbiol (1977) 2.99

Further biochemical characterization, including the detection of surface glycoproteins, of human, calf, and simian rotaviruses. J Virol (1977) 2.60

Cell culture propagation of porcine rotavirus (reovirus-like agent). Am J Vet Res (1977) 2.51

Characterization of two particle types of calf rotavirus. J Gen Virol (1976) 2.35

Rotavirus polypeptides. J Gen Virol (1979) 2.23

Characterisation of a rotavirus.20b. Nature (1975) 2.21

The interaction of a series of hybridoma IgGs with reovirus particles. Demonstration that the core protein lambda 2 is exposed on the particle surface. Virology (1981) 1.98

The effect of trypsin on the growth of rotavirus. J Gen Virol (1978) 1.86

Polypeptides of bovine rotavirus. J Gen Virol (1979) 1.85

Proteolytic enhancement of rotavirus infectivity: biology mechanism. Virology (1980) 1.81

Production of high-titer bovine rotavirus with trypsin. J Clin Microbiol (1979) 1.80

Effect of enzymes on rotavirus infectivity. J Clin Microbiol (1979) 1.79

Biochemical studies on a reovirus-like agent (rotovirus) from lambs. J Virol (1977) 1.67

Biochemical characterization of infantile gastroenteritis virus (IGV). J Gen Virol (1977) 1.56

Polypeptides of simian rotavirus (SA-11) determined by a continuous polyacrylamide gel electrophoresis method. J Gen Virol (1979) 1.36

Articles by these authors

Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial. Ann Intern Med (1995) 9.77

Expression, self-assembly, and antigenicity of the Norwalk virus capsid protein. J Virol (1992) 8.35

Rotavirus gene structure and function. Microbiol Rev (1989) 6.95

X-ray crystallographic structure of the Norwalk virus capsid. Science (1999) 6.58

Sequence and genomic organization of Norwalk virus. Virology (1993) 6.25

Current concepts in the management of Helicobacter pylori infection--the Maastricht 2-2000 Consensus Report. Aliment Pharmacol Ther (2002) 6.17

Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrob Agents Chemother (1996) 6.01

Norwalk virus genome cloning and characterization. Science (1990) 5.83

Rotaviruses: a review. Curr Top Microbiol Immunol (1983) 5.24

Campylobacter pylori detected noninvasively by the 13C-urea breath test. Lancet (1987) 5.02

Structural polypeptides of simian virus 40. J Virol (1971) 4.83

In vitro transcription and translation of simian rotavirus SA11 gene products. J Virol (1980) 4.40

Norwalk virus infection of volunteers: new insights based on improved assays. J Infect Dis (1994) 4.37

Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial. JAMA (1999) 4.25

Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countries. J Clin Microbiol (1999) 4.13

Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype. Gastroenterology (1998) 4.12

Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein. Science (1996) 4.08

Taxonomy of the caliciviruses. J Infect Dis (2000) 3.94

Detection of Norwalk virus in stool by polymerase chain reaction. J Clin Microbiol (1992) 3.82

A sensitive and specific serologic test for detection of Campylobacter pylori infection. Gastroenterology (1989) 3.66

A M(r) 34,000 proinflammatory outer membrane protein (oipA) of Helicobacter pylori. Proc Natl Acad Sci U S A (2000) 3.66

Rotavirus infections in infants as protection against subsequent infections. N Engl J Med (1996) 3.61

Interobserver variation in the histopathological assessment of Helicobacter pylori gastritis. Hum Pathol (1996) 3.57

The course of patients after variceal hemorrhage. Gastroenterology (1981) 3.33

Population genetic analysis of Helicobacter pylori by multilocus enzyme electrophoresis: extensive allelic diversity and recombinational population structure. J Bacteriol (1996) 3.32

Variants of the 3' region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases. J Clin Microbiol (1998) 3.31

Diagnosis of noncultivatable gastroenteritis viruses, the human caliciviruses. Clin Microbiol Rev (2001) 3.28

Specific enzyme-linked immunoassay for rotavirus serotypes 1 and 3. J Clin Microbiol (1985) 3.23

Allelic variation in the cagA gene of Helicobacter pylori obtained from Korea compared to the United States. Am J Gastroenterol (1996) 3.20

N-acetylneuraminyllactose-binding fibrillar hemagglutinin of Campylobacter pylori: a putative colonization factor antigen. Infect Immun (1988) 3.16

Water source as risk factor for Helicobacter pylori infection in Peruvian children. Gastrointestinal Physiology Working Group. Lancet (1991) 3.09

Gastric lymphoid follicles in Helicobacter pylori infection: frequency, distribution, and response to triple therapy. Hum Pathol (1993) 2.96

Norwalk virus open reading frame 3 encodes a minor structural protein. J Virol (2000) 2.96

Ultrastructural localization of rotavirus antigens using colloidal gold. Virus Res (1984) 2.95

Relationship of Helicobacter pylori to serum pepsinogens in an asymptomatic Japanese population. Gastroenterology (1992) 2.83

Localization of VP4 neutralization sites in rotavirus by three-dimensional cryo-electron microscopy. Nature (1990) 2.77

Detection of Norwalk virus and hepatitis A virus in shellfish tissues with the PCR. Appl Environ Microbiol (1995) 2.73

Correlation of patient immune responses with genetically characterized small round-structured viruses involved in outbreaks of nonbacterial acute gastroenteritis in the United States, 1990 to 1995. J Med Virol (1997) 2.70

Detection of enteric viruses in oysters by using the polymerase chain reaction. Appl Environ Microbiol (1993) 2.69

Identification, synthesis, and modifications of simian rotavirus SA11 polypeptides in infected cells. J Virol (1982) 2.67

A plaque assay for the simian rotavirus SAII. J Gen Virol (1979) 2.65

A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori. Antimicrob Agents Chemother (1997) 2.63

Three-dimensional visualization of mRNA release from actively transcribing rotavirus particles. Nat Struct Biol (1997) 2.63

Variceal hemorrhage: a critical evaluation of survival analysis. Gastroenterology (1982) 2.60

Comparison of the reactivities of baculovirus-expressed recombinant Norwalk virus capsid antigen with those of the native Norwalk virus antigen in serologic assays and some epidemiologic observations. J Clin Microbiol (1993) 2.58

Recombinant Norwalk virus-like particles given orally to volunteers: phase I study. Gastroenterology (1999) 2.54

Attachment and entry of recombinant Norwalk virus capsids to cultured human and animal cell lines. J Virol (1996) 2.51

Rotavirus stability and inactivation. J Gen Virol (1979) 2.48

Characterization of virus-like particles produced by the expression of rotavirus capsid proteins in insect cells. J Virol (1994) 2.48

Point mutations in the 23S rRNA gene of Helicobacter pylori associated with different levels of clarithromycin resistance. J Antimicrob Chemother (1997) 2.47

Helicobacter pylori infection: genetic and environmental influences. A study of twins. Ann Intern Med (1994) 2.47

Three-dimensional structure of baculovirus-expressed Norwalk virus capsids. J Virol (1994) 2.46

Visualization of ordered genomic RNA and localization of transcriptional complexes in rotavirus. Nature (1996) 2.45

Relationship between the cagA 3' repeat region of Helicobacter pylori, gastric histology, and susceptibility to low pH. Gastroenterology (1999) 2.44

Patients, payers, and paradigm shifts: what to do about Helicobacter pylori. Am J Gastroenterol (1996) 2.43

Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome. Helicobacter (1998) 2.39

Expression of rotavirus VP2 produces empty corelike particles. J Virol (1991) 2.38

Demonstration of unexpected antibiotic resistance of genotypically identical Helicobacter pylori isolates. Clin Infect Dis (1998) 2.38

Fundic gland polyps developing during omeprazole therapy. Am J Gastroenterol (1997) 2.37

Comparison of biopsy sites for the histopathologic diagnosis of Helicobacter pylori: a topographic study of H. pylori density and distribution. Gastrointest Endosc (1994) 2.36

Cimetidine, cigarette smoking, and recurrence of duodenal ulcer. N Engl J Med (1984) 2.29

Synthesis and immunogenicity of the rotavirus major capsid antigen using a baculovirus expression system. J Virol (1987) 2.29

Application of PCR to detect Norwalk virus in fecal specimens from outbreaks of gastroenteritis. J Clin Microbiol (1994) 2.27

Structure and function of the polypeptides in simian virus 40. I. Existence of subviral deoxynucleoprotein complexes. J Virol (1972) 2.16

Simultaneous visualization of Helicobacter pylori and gastric morphology: a new stain. Hum Pathol (1994) 2.16

Importance of childhood socioeconomic status on the current prevalence of Helicobacter pylori infection. Gut (1994) 2.14

Environmental virology: from detection of virus in sewage and water by isolation to identification by molecular biology--a trip of over 50 years. Annu Rev Microbiol (1995) 2.13

Inappropriate hypergastrinaemia in asymptomatic healthy subjects infected with Helicobacter pylori. Gut (1990) 2.13

Evaluation of a degenerate primer for the PCR detection of human caliciviruses. Arch Virol (1996) 2.11

Identification of the simian rotavirus SA11 genome segment 3 product. Virology (1988) 2.10

Pancreatic-biliary ascariasis: experience of 300 cases. Am J Gastroenterol (1997) 2.10

Receptor activity of rotavirus nonstructural glycoprotein NS28. J Virol (1989) 2.09

Functional and topographical analyses of epitopes on the hemagglutinin (VP4) of the simian rotavirus SA11. J Virol (1988) 2.08

Mycobacteria and inflammatory bowel disease. Results of culture. Gastroenterology (1987) 2.07

Polymerase chain reaction detection of Mycobacterium paratuberculosis and Mycobacterium avium subsp silvaticum in long term cultures from Crohn's disease and control tissues. Gut (1992) 2.06

Nucleic acid hybridization studies of mycobactin-dependent mycobacteria. J Clin Microbiol (1988) 2.06

Gastroduodenal mucosa and dyspeptic symptoms in arthritic patients during chronic nonsteroidal anti-inflammatory drug use. Am J Gastroenterol (1987) 2.05

Human immune responses to a novel norwalk virus vaccine delivered in transgenic potatoes. J Infect Dis (2000) 2.02

Antigenic mapping of the recombinant Norwalk virus capsid protein using monoclonal antibodies. Virology (1996) 2.01

Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice. Proc Natl Acad Sci U S A (1996) 2.00

Clarithromycin as monotherapy for eradication of Helicobacter pylori: a randomized, double-blind trial. Am J Gastroenterol (1993) 2.00

Detection of hepatitis A virus by hybridization with single-stranded RNA probes. Appl Environ Microbiol (1987) 1.98

Molecular epidemiology of Helicobacter pylori: separation of H. pylori from East Asian and non-Asian countries. Epidemiol Infect (2000) 1.97

Characterization of a Helicobacter pylori neutrophil-activating protein. Infect Immun (1995) 1.97

Rotavirus virus-like particles administered mucosally induce protective immunity. J Virol (1997) 1.96

Helicobacter pylori in the drinking water in Peru. Gastroenterology (1996) 1.95

Detection of Helicobacter pylori in dental plaque by reverse transcription-polymerase chain reaction. J Clin Microbiol (1993) 1.94

Identification of minireovirus as a Norwalk-like virus in pediatric patients with gastroenteritis. J Virol (1994) 1.93

Detection of Mycobacterium avium subspecies paratuberculosis in Crohn's diseased tissues by in situ hybridization. Am J Gastroenterol (2001) 1.93