Published in Nature on March 18, 1982
An Alu transposition model for the origin and expansion of human segmental duplications. Am J Hum Genet (2003) 5.33
Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis. J Virol (1984) 4.72
The minimum amount of homology required for homologous recombination in mammalian cells. Mol Cell Biol (1984) 4.39
Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats. Nucleic Acids Res (1984) 3.15
Sequence of an expressed human beta-tubulin gene containing ten Alu family members. Nucleic Acids Res (1984) 3.08
AT-rich palindromes mediate the constitutional t(11;22) translocation. Am J Hum Genet (2000) 2.21
Location of Homologous DNA Sequences Interspersed at Five Regions in the Baculovirus AcMNPV Genome. J Virol (1983) 2.01
Recombination events after transient infection and stable integration of DNA into mouse cells. Mol Cell Biol (1985) 1.99
Extrachromosomal copies of transposon Tc1 in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1984) 1.91
Alternative splicing of human elastin mRNA indicated by sequence analysis of cloned genomic and complementary DNA. Proc Natl Acad Sci U S A (1987) 1.87
Factors affecting inverted repeat stimulation of recombination and deletion in Saccharomyces cerevisiae. Genetics (1998) 1.78
A novel chromatin immunoprecipitation and array (CIA) analysis identifies a 460-kb CENP-A-binding neocentromere DNA. Genome Res (2001) 1.75
One short well conserved region of Alu-sequences is involved in human gene rearrangements and has homology with prokaryotic chi. Nucleic Acids Res (1995) 1.49
A hotspot for novel amplification joints in a mosaic of Alu-like repeats and palindromic A + T-rich DNA. EMBO J (1987) 1.47
Chemicals, cancer and cancer biology. West J Med (1983) 1.46
A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma. EMBO J (1992) 1.46
Genomewide-linkage and haplotype-association studies map intracranial aneurysm to chromosome 7q11. Am J Hum Genet (2001) 1.43
Rapid assay for extrachromosomal homologous recombination in monkey cells. Mol Cell Biol (1985) 1.42
Identification of an endogenous plasmid in Dictyostelium discoideum. EMBO J (1983) 1.39
Characterization of cloned human alphoid satellite with an unusual monomeric construction: evidence for enrichment in HeLa small polydisperse circular DNA. Nucleic Acids Res (1985) 1.38
The Alu family repeat promoter has a tRNA-like bipartite structure. EMBO J (1983) 1.36
Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting. Proc Natl Acad Sci U S A (1983) 1.30
L1 sequences in HeLa extrachromosomal circular DNA: evidence for circularization by homologous recombination. Proc Natl Acad Sci U S A (1985) 1.24
Analysis of the 3' flanking region of the human c-myc gene in lymphomas with the t(8;22) and t(2;8) chromosomal translocations. Nucleic Acids Res (1986) 1.22
Structural organization of glycophorin A and B genes: glycophorin B gene evolved by homologous recombination at Alu repeat sequences. Proc Natl Acad Sci U S A (1989) 1.19
Cloning and characterization of small circular DNA from Chinese hamster ovary cells. Mol Cell Biol (1984) 1.19
Repetitive satellite-like sequences are present within or upstream from 3 avian protein-coding genes. Nucleic Acids Res (1983) 1.12
Alu sequences transcription in X. laevis oocytes: nuclear-cytoplasmic partitioning and evidence for 3' end processing reactions. Nucleic Acids Res (1985) 1.10
Interspersed repetitive and tandemly repetitive sequences are differentially represented in extrachromosomal covalently closed circular DNA of human diploid fibroblasts. Nucleic Acids Res (1985) 0.99
How many processed pseudogenes are accumulated in a gene family? Genetics (1985) 0.97
Cloning, sequencing, and analysis of inv8 chromosome breakpoints associated with recombinant 8 syndrome. Am J Hum Genet (2000) 0.96
Human satellite I sequences include a male specific 2.47 kb tandemly repeated unit containing one Alu family member per repeat. Nucleic Acids Res (1984) 0.96
A novel transposon-like repeat interrupted by an LTR element occurs in a cluster of B1 repeats in the mouse c-mos locus. Nucleic Acids Res (1984) 0.93
New class of polyomavirus mutant that can persist as free copies in F9 embryonal carcinoma cells. Mol Cell Biol (1986) 0.93
A tissue-specific change in repetitive DNA in rats. Proc Natl Acad Sci U S A (1989) 0.91
DNA sequence homology between the terminal inverted repeats of Shope fibroma virus and an endogenous cellular plasmid species. Mol Cell Biol (1986) 0.88
Transposition of an Alu-containing element induced by DNA-advanced glycosylation endproducts. Proc Natl Acad Sci U S A (1993) 0.88
Extrachromosomal circular nuclear rDNA in Euglena gracilis. Nucleic Acids Res (1985) 0.86
A region of extreme instability in the mitochondrial genome of yeast. EMBO J (1982) 0.85
Carcinogens induce reversion of the mouse pink-eyed unstable mutation. Proc Natl Acad Sci U S A (1997) 0.83
DNA sequence of the excision sites of a mitochondrial plasmid from senescent Podospora anserina. Nucleic Acids Res (1983) 0.82
Identification of a precursor genomic segment that provided a sequence unique to glycophorin B and E genes. Proc Natl Acad Sci U S A (1993) 0.82
Immunoglobulin switch region-like sequences in Drosophila melanogaster. Nucleic Acids Res (1982) 0.82
The structure of HSAG-1, a middle repetitive genetic element which elicits a leukemia-related cellular surface antigen. Nucleic Acids Res (1986) 0.76
One in four individuals of African-American ancestry harbors a 5.5kb deletion at chromosome 11q13.1. Genomics (2014) 0.75
A long interspersed (LINE) DNA exhibiting polymorphic patterns in human genomes. Proc Natl Acad Sci U S A (1986) 0.75
Molecular characterization of a mouse genomic element mobilized by advanced glycation endproduct modified-DNA (AGE-DNA). Mol Med (1997) 0.75
Localization of single copy DNA sequences of G-banded human chromosomes by in situ hybridization. Chromosoma (1981) 9.30
Mouse small eye results from mutations in a paired-like homeobox-containing gene. Nature (1992) 6.32
A novel closed-circular mitochondrial DNA with properties of a replicating intermediate. Proc Natl Acad Sci U S A (1971) 5.33
DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA. Cell (1995) 4.98
Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells. Proc Natl Acad Sci U S A (1972) 4.38
Extracellular nucleases of Pseudomonas BAL 31. I. Characterization of single strand-specific deoxyriboendonuclease and double-strand deoxyriboexonuclease activities. Nucleic Acids Res (1975) 4.16
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. EMBO J (1997) 3.34
Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Proc Natl Acad Sci U S A (1981) 3.17
Base composition of deoxyribonucleic acid of sulfate-reducing bacteria deduced from buoyant density measurements in cesium chloride. J Bacteriol (1964) 2.89
A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science (1988) 2.88
Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA cyclin. Science (1988) 2.74
Replication of mitochondrial DNA in mouse L cells and their thymidine kinase - derivatives: displacement replication on a covalently-closed circular template. Proc Natl Acad Sci U S A (1972) 2.49
Characterization of a thermophilic bacteriophage for Bacillus stearothermophilus. J Bacteriol (1966) 2.43
Coding sequence and growth regulation of the human vimentin gene. Mol Cell Biol (1986) 2.34
The human growth hormone locus: nucleotide sequence, biology, and evolution. Genomics (1989) 2.17
Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis. Mol Cell Biol (1999) 2.17
Polyoma virus--a study of wild-type, mutant and defective DNAs. Cold Spring Harb Symp Quant Biol (1975) 2.17
The synthesis and properties of the complete complementary DNA transcript of ovalbumin mRNA. Biochemistry (1976) 2.08
Nonrandom loss of maternal chromosome 11 alleles in Wilms tumors. Am J Hum Genet (1987) 2.06
Expression of cell-cycle-dependent genes in phytohemagglutinin-stimulated human lymphocytes. Proc Natl Acad Sci U S A (1985) 2.01
Preparation of pancreatic mRNA: cell-free translation of an insulin-immunoreactive polypeptide. Nucleic Acids Res (1976) 1.99
An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc Natl Acad Sci U S A (1989) 1.98
G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb. Science (1989) 1.96
Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides. Science (1991) 1.93
Ribonucleic acid and ribosomes of Bacillus stearothermophilus. J Bacteriol (1966) 1.80
Presence of messenger specifying sequences in the DNA of chromatin subunits. Proc Natl Acad Sci U S A (1976) 1.75
Antitumor effect of c-myc antisense phosphorothioate oligodeoxynucleotides on human melanoma cells in vitro and and in mice. J Natl Cancer Inst (1996) 1.74
Double-helical regions in nuclear precursor of mRNA (pre-mRNA). Biochim Biophys Acta (1973) 1.73
The use of RNA labeled in vitro with iodine-125 in molecular hybridization experiments. Biochim Biophys Acta (1972) 1.72
Regulation of the proliferating cell nuclear antigen cyclin and thymidine kinase mRNA levels by growth factors. J Biol Chem (1988) 1.70
Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells. Blood (1995) 1.69
Pulse-labeled components in the replication of mitochondrial deoxyribonucleic acid. J Biol Chem (1973) 1.69
Presence of a highly repetitive and widely dispersed DNA sequence in the human genome. Proc Natl Acad Sci U S A (1981) 1.67
Lack of linkage of familial Wilms' tumour to chromosomal band 11p13. Nature (1988) 1.67
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1. Leukemia (2012) 1.65
Populations of repeated DNA sequences in the human genome. J Mol Biol (1972) 1.62
Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis. J Exp Med (1999) 1.61
Sequence arrangements in clonal isolates of polyoma defective DNA. Proc Natl Acad Sci U S A (1974) 1.60
Expression of the Wilms' tumor gene (WT1) in human leukemias. Leukemia (1992) 1.60
TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis. EMBO J (1998) 1.60
A sensitive endonuclease probe for lesions in deoxyribonucleic acid helix structure produced by carcinogenic or mutagenic agents. J Biol Chem (1977) 1.59
Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene. Mol Cell Biol (1991) 1.58
Chromosomal localization of the human placental lactogen-growth hormone gene cluster to 17q22-24. Am J Hum Genet (1982) 1.57
Structure of the human gene for the proliferating cell nuclear antigen. J Biol Chem (1989) 1.56
Mammalian pancreatic preproglucagon contains three glucagon-related peptides. Proc Natl Acad Sci U S A (1983) 1.51
Treatment of Philadelphia leukemia in severe combined immunodeficient mice by combination of cyclophosphamide and bcr/abl antisense oligodeoxynucleotides. J Natl Cancer Inst (1997) 1.47
Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1. Cancer Res (1995) 1.46
p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. Cancer Res (1994) 1.46
Cleavage of replicating forms of mitochondrial DNA by EcoRI endonuclease. Proc Natl Acad Sci U S A (1974) 1.44
Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. J Clin Invest (1997) 1.44
De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells. Proc Natl Acad Sci U S A (1995) 1.43
Familial renal cell carcinoma: hereditary or coincidental? J Urol (1990) 1.39
Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis. Proc Natl Acad Sci U S A (1999) 1.39
Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT. Am J Hum Genet (1991) 1.39
Molecular cloning of the cDNA for a growth factor-inducible gene with strong homology to S-100, a calcium-binding protein. J Biol Chem (1986) 1.36
Structural and functional analysis of a growth-regulated gene, the human calcyclin. J Biol Chem (1987) 1.36
Truncation mutations in the transactivation region of PAX6 result in dominant-negative mutants. J Biol Chem (1998) 1.35
c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene. J Biol Chem (1993) 1.34
Bleomycin-specific fragmentation of double-stranded DNA. Biochemistry (1978) 1.32
mRNA in human cells contains sequences complementary to the Alu family of repeated DNA. Proc Natl Acad Sci U S A (1981) 1.32
c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings. Am J Pathol (2001) 1.29
Paired box mutations in familial and sporadic aniridia predicts truncated aniridia proteins. Am J Hum Genet (1994) 1.29
The structure of the human apolipoprotein C-II gene. Electron microscopic analysis of RNA:DNA hybrids, complete nucleotide sequence, and identification of 5' homologous sequences among apolipoprotein genes. J Biol Chem (1985) 1.28
Molecular cloning of a cDNA for a human ADP/ATP carrier which is growth-regulated. J Biol Chem (1987) 1.27
Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. Proc Natl Acad Sci U S A (1995) 1.26
Chromosomal localization of the human alpha 1-antitrypsin gene (PI) to 14q31-32. Am J Hum Genet (1985) 1.26
Distal deletion of chromosome Ip in ductal carcinoma of the breast. Am J Hum Genet (1989) 1.25
Recent amplification of an alpha satellite DNA in humans. Nucleic Acids Res (1985) 1.25
Overexpression of the zinc finger protein MZF1 inhibits hematopoietic development from embryonic stem cells: correlation with negative regulation of CD34 and c-myb promoter activity. Mol Cell Biol (1995) 1.24
Localization of sequences specifying messenger RNA to light-staining G-bands of human chromosomes. Chromosoma (1977) 1.24
Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity. Proc Natl Acad Sci U S A (1997) 1.24
Mitosis-specific monoclonal antibody MPM-2 inhibits Xenopus oocyte maturation and depletes maturation-promoting activity. Proc Natl Acad Sci U S A (1989) 1.23
Properties of the deoxyribonucleic acid of the thermophilic bacteriophage TP-84. Biochemistry (1965) 1.23
Regulation of BALB/c 3T3 fibroblast proliferation by B-myb is accompanied by selective activation of cdc2 and cyclin D1 expression. Proc Natl Acad Sci U S A (1992) 1.23
Oligonucleotide N3'-->P5' phosphoramidates as antisense agents. Nucleic Acids Res (1996) 1.22
Localization of the human glucagon gene (GCG) to chromosome segment 2q36----37. Cytogenet Cell Genet (1984) 1.22
Caspase cleavage enhances the apoptosis-inducing effects of BAD. Mol Cell Biol (2001) 1.21
The SH3 domain contributes to BCR/ABL-dependent leukemogenesis in vivo: role in adhesion, invasion, and homing. Blood (1998) 1.20
Dissection of the transactivation function of the transcription factor encoded by the eye developmental gene PAX6. J Biol Chem (1998) 1.19
Localization of repetitive DNA in the chromosomes of Microtus agrestis by means of in situ hybridization. Chromosoma (1970) 1.19
Control of hsp70 RNA levels in human lymphocytes. J Cell Biol (1987) 1.19
c-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice. Cancer Res (1998) 1.19
Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide. Proc Natl Acad Sci U S A (1994) 1.19
Two structurally different genes produce the same secreted human placental lactogen hormone. J Biol Chem (1983) 1.18
Long range physical map of the Wilms' tumor-aniridia region on human chromosome 11. Cell (1988) 1.18
Inhibition of T-cell proliferation by a MYB antisense oligomer is accompanied by selective down-regulation of DNA polymerase alpha expression. Proc Natl Acad Sci U S A (1990) 1.18
Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity. Nucleic Acids Res (2001) 1.17
The replication and structure of mitochondrial DNA in animal cells. Cold Spring Harb Symp Quant Biol (1974) 1.17
Structure of the human glucagon gene. Nucleic Acids Res (1986) 1.17
Properties of 5-fluorouracil-containing ribonucleic acid and ribosomes from Bacillus subtilis. J Bacteriol (1968) 1.16
Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase. Proc Natl Acad Sci U S A (1996) 1.15
A panel of restriction fragment length polymorphisms for chromosomal band 11p13. Hum Genet (1990) 1.15
Inhibition of leukemia cell proliferation by receptor-mediated uptake of c-myb antisense oligodeoxynucleotides. Proc Natl Acad Sci U S A (1992) 1.14
Cell-cycle-specific genes differentially expressed in human leukemias. Proc Natl Acad Sci U S A (1985) 1.14