Published in Proc Natl Acad Sci U S A on April 01, 1982
Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. Proc Natl Acad Sci U S A (1986) 3.68
Two related but differentially expressed potential membrane proteins encoded by the EcoRI Dhet region of Epstein-Barr virus B95-8. J Virol (1985) 2.82
Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens. J Exp Med (1986) 2.17
Characterization of an antigen whose cell surface expression is induced by infection with Epstein-Barr virus. J Virol (1983) 1.32
AIDS-related Kaposi's sarcoma displays differential expression of endothelial surface antigens. Am J Pathol (1988) 1.01
Selective inhibition of growth factor-dependent human B cell proliferation by monoclonal antibody AB1 to an antigen expressed by activated B cells. J Exp Med (1984) 1.00
Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature (1977) 16.54
Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood (1975) 15.95
Cellular localization of an Epstein-Barr virus (EBV)-associated complement-fixing antigen in producer and non-producer lymphoblastoid cell lines. Int J Cancer (1973) 14.90
Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture. Nature (1977) 12.57
Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes. J Natl Cancer Inst (1972) 10.15
Two populations of Ia-like molecules on a human B cell line. J Immunol (1980) 7.68
Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines. Eur J Immunol (1976) 7.64
ENZYMATIC DIGESTION OF RABBIT GAMMA GLOBULIN AND ANTIBODY AND CHROMATOGRAPHY OF DIGESTION PRODUCTS. Methods Med Res (1964) 6.44
Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma. Biomedicine (1975) 4.68
An EBV-genome-negative cell line established from an American Burkitt lymphoma; receptor characteristics. EBV infectibility and permanent conversion into EBV-positive sublines by in vitro infection. Intervirology (1975) 4.48
Cytotoxic effector cells specific for B Cell lines transformed by Epstein-Barr virus are present in patients with infectious mononucleosis. Proc Natl Acad Sci U S A (1975) 4.21
Monoclonal antibody against a 250,000-dalton glycoprotein of Epstein-Barr virus identifies a membrane antigen and a neutralizing antigen. Proc Natl Acad Sci U S A (1980) 3.77
Human lymphoblastoid lines from lymph node and spleen. Cancer (1968) 2.85
Monoclonal antibodies against the major glycoprotein (gp350/220) of Epstein-Barr virus neutralize infectivity. Proc Natl Acad Sci U S A (1980) 2.59
Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin. J Immunol (1980) 2.54
In vitro effects of Epstein-Barr virus on peripheral blood mononuclear cells from patients with rheumatoid arthritis and normal subjects. J Exp Med (1978) 2.34
Epstein-barr virus-negative human malignant T-cell lines. J Exp Med (1974) 2.28
Identification of antigenic determinants unique to the surfaces of cells transformed by Epstein-Barr virus. Nature (1981) 2.27
Two E-rosette-forming lymphoid cell lines. Int J Cancer (1978) 2.09
Direct implantation and serial transplantation of human acute lymphoblastic leukemia in hamsters, SB-2. Cancer Res (1968) 1.87
Polypeptides of the Epstein-Barr virus membrane antigen complex. J Virol (1979) 1.86
Characterization of a leukemic cell line of the pre-B phenotype. Int J Cancer (1979) 1.76
A non-T, non-B human leukemia cell line (NALM-1): establishment of the cell line and presence of leukemia-associated antigens. J Natl Cancer Inst (1977) 1.75
Cytogenetic study of human lymphoid T-cell lines derived from lymphocytic leukemia. J Natl Cancer Inst (1974) 1.51
Relationship between the EBV-associated membrane antigen on Burkitt lymphoma cells and the viral envelope, demonstrated by immunoferritin labelling. Int J Cancer (1971) 1.50
Observations on the EB virus envelope and virus-determined membrane antigen (MA) polypeptides. Int J Cancer (1980) 1.41
Identification of Epstein-Barr virus strain differences with monoclonal antibody to a membrane glycoprotein. Proc Natl Acad Sci U S A (1982) 1.39
Differentiation between early and late membrane antigen on human lymphoblastoid cell lines infected with Epstein-Barr virus. I. Immunofluorescence. J Natl Cancer Inst (1974) 1.18
Antibody-dependent cellular cytotoxicity (ADCC) against Epstein-Barr virus-determined membrane antigens. I. Reactivity in sera from normal persons and from patients with acute infectious mononucleosis. Clin Exp Immunol (1976) 1.09
Inhibition of the in vitro outgrowth of Epstein-Barr virus-transformed lymphocytes by thymus-dependent lymphocytes from infectious mononucleosis patients. Clin Exp Immunol (1977) 0.98
T lymphocyte-mediated cytotoxicity against autologous EBV-genome-bearing B cells. J Immunol (1981) 0.93
Human leukemic "null" cell line (NALL-1). Cancer (1977) 0.92
Antigenic properties and molecular weights of murine leukemia virus-binding proteins. J Immunol (1979) 0.91
Appearance of early and late components of Epstein-Barr virus-associated membrane antigen in Daudi cells superinfected with P3HR-1 virus. J Gen Virol (1978) 0.89
Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature (1988) 6.38
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (1994) 6.06
IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma. Blood (1997) 4.97
1,25-dihydroxyvitamin D3 receptors in human leukocytes. Science (1983) 4.34
IDEC-C2B8: results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma. J Clin Oncol (1997) 4.32
Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat Med (1997) 4.12
Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science (1996) 3.82
A chronic illness characterized by fatigue, neurologic and immunologic disorders, and active human herpesvirus type 6 infection. Ann Intern Med (1992) 3.42
Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol (1989) 3.01
Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science (1988) 2.96
Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s). Proc Natl Acad Sci U S A (1977) 2.90
Activators of the nuclear receptor PPARgamma enhance colon polyp formation. Nat Med (1998) 2.90
B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes. J Exp Med (1988) 2.88
Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis. J Clin Invest (1989) 2.83
Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1. J Clin Invest (1991) 2.82
Human immunodeficiency virus infection of human-PBL-SCID mice. Science (1991) 2.77
THE INFLUENCE OF IODINE ON THE EXCRETION OF CREATINE IN EXOPHTHALMIC GOITER. J Clin Invest (1929) 2.73
Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc Natl Acad Sci U S A (1994) 2.58
Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin. J Immunol (1980) 2.54
1,25-dihydroxyvitamin D3: a novel immunoregulatory hormone. Science (1984) 2.48
Intracytoplasmic inclusions of immunoglobulins in rheumatoid arthritis and other diseases. Arthritis Rheum (1968) 2.44
Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives. J Biol Chem (1988) 2.41
In vitro effects of Epstein-Barr virus on peripheral blood mononuclear cells from patients with rheumatoid arthritis and normal subjects. J Exp Med (1978) 2.34
Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells. J Natl Cancer Inst (2000) 2.33
Synovial fluid lymphocytes differ from peripheral blood lymphocytes in patients with rheumatoid arthritis. J Immunol (1982) 2.22
Radioimmunoassay of IgG and IgM rheumatoid factors reacting with human IgG. J Immunol (1977) 2.21
Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J Exp Med (1996) 2.18
The association of genital herpesvirus with cervical atypia and carcinoma in situ. Am J Epidemiol (1970) 2.17
Immunohistologic analysis of lymphoid infiltrates in primary Sjogren's syndrome using monoclonal antibodies. J Immunol (1983) 2.09
Leukocyte procoagulant activity: enhancement of production in vitro by IgG and antigen-antibody complexes. J Clin Invest (1977) 2.07
A methylthioadenosine phosphorylase (MTAP) fusion transcript identifies a new gene on chromosome 9p21 that is frequently deleted in cancer. Oncogene (2000) 2.07
Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells. J Exp Med (1986) 2.04
Antinuclear antibodies following hydralazine toxicity. N Engl J Med (1967) 2.02
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci U S A (1996) 2.01
Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes. J Clin Invest (1985) 1.98
Substance P activation of rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis. Science (1987) 1.97
A conserved human germline V kappa gene directly encodes rheumatoid factor light chains. J Exp Med (1986) 1.92
IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro. J Immunol (1990) 1.82
Expression and function of wingless and frizzled homologs in rheumatoid arthritis. Proc Natl Acad Sci U S A (2000) 1.81
Isolation of human PMN leukocytes and granules: observations on early blood diluion and on heparin. J Lab Clin Med (1968) 1.79
Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line. Proc Natl Acad Sci U S A (1978) 1.79
Thymidine kinase obliteration: creation of transgenic mice with controlled immune deficiency. Proc Natl Acad Sci U S A (1989) 1.74
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy. J Exp Med (1988) 1.73
Characterization of an IgA rheumatoid factor: finding properties and reactivity with the subclasses of human G globulin. Immunochemistry (1972) 1.73
Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines. Proc Natl Acad Sci U S A (1979) 1.72
Rheumatoid factor and immune networks. Annu Rev Immunol (1987) 1.70
Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (1989) 1.66
2-Chlorodeoxyadenosine treatment of low-grade lymphomas. J Clin Oncol (1992) 1.65
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. J Exp Med (1987) 1.65
A common idiotope on human rheumatoid factors identified by a hybridoma antibody. Mol Immunol (1983) 1.65
Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis. Arthritis Rheum (1984) 1.65
Rheumatoid factor-producing cells detected by direct hemolytic plaque assay. J Clin Invest (1976) 1.62
Detection of Epstein-Barr virus-associated antigens and DNA in salivary gland biopsies from patients with Sjogren's syndrome. J Immunol (1986) 1.62
IgG rheumatoid factor in subacute bacterial endocarditis: relationship to IgM rheumatoid factor and circulating immune complexes. Clin Exp Immunol (1978) 1.62
DNA strand breaks, NAD metabolism, and programmed cell death. Exp Cell Res (1986) 1.60
Complement fixation by rheumatoid factor. J Clin Invest (1975) 1.60
Use of monoclonal antibodies to analyze peripheral blood and salivary gland lymphocyte subsets in Sjögren's syndrome. Arthritis Rheum (1982) 1.58
Altered lymphocyte reactivity in rheumatoid arthritis. Arthritis Rheum (1976) 1.58
The distribution of serum immunoglobulins, anti-gamma-G globulins ("rheumatoid factors") and antinuclear antibodies in White and Negro subjects in Evans County, Georgia. Arthritis Rheum (1967) 1.57
A 16/6 idiotype-positive anti-DNA antibody is encoded by a conserved VH gene with no somatic mutation. Arthritis Rheum (1988) 1.56
Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection. Proc Natl Acad Sci U S A (1990) 1.55
Regulation of Epstein-Barr virus infection by recombinant interferons. Selected sensitivity to interferon-gamma. Eur J Immunol (1985) 1.55
UC 729-6, a human lymphoblastoid B-cell line useful for generating antibody-secreting human-human hybridomas. Proc Natl Acad Sci U S A (1983) 1.54
Evidence for the presence of receptors for C3 and IgG Fc on human synovial cells. Arthritis Rheum (1980) 1.54
Transforming growth factor-beta and cellular immune responses in synovial fluids. J Immunol (1990) 1.53
Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes. J Immunol (1985) 1.53
Substituted isoquinolines and quinazolines as potential antiinflammatory agents. Synthesis and biological evaluation of inhibitors of tumor necrosis factor alpha. J Med Chem (1999) 1.52
Susceptibility to rheumatoid arthritis maps to a T-cell epitope shared by the HLA-Dw4 DR beta-1 chain and the Epstein-Barr virus glycoprotein gp110. Proc Natl Acad Sci U S A (1989) 1.52
Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Barr virus nuclear antigen. J Exp Med (1987) 1.50
Anti-hypervariable region antibody induced by a defined peptide: an approach for studying the structural correlates of idiotypes. Proc Natl Acad Sci U S A (1984) 1.50
Antibody formation in dysgammaglobulinemia. J Clin Invest (1966) 1.50
Autologous human B and T lymphoblastoid cell lines. Nature (1974) 1.48
Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood (2000) 1.47
Blockade of Wnt-5A/frizzled 5 signaling inhibits rheumatoid synoviocyte activation. Arthritis Rheum (2001) 1.46
The significance of antinuclear factors in rheumatoid arthritis. Arthritis Rheum (1965) 1.46
Relation of intracytoplasmic inclusions in joint fluid leukocytes to anti-gamma-G globulins. Arthritis Rheum (1968) 1.46
Basis for defective responses of rheumatoid arthritis synovial fluid lymphocytes to anti-CD3 (T3) antibodies. J Clin Invest (1986) 1.46
IgA rheumatoid factor in the sera and saliva of patients with rheumatoid arthritis and Sjögren's syndrome. Ann Rheum Dis (1979) 1.45
Autoantibodies and the spectrum of Sjögren's syndrome. Ann Intern Med (1979) 1.44
Antibodies to Epstein-Barr virus-determined antigens in normal subjects and in patients with seropositive rheumatoid arthritis. Proc Natl Acad Sci U S A (1979) 1.44