Published in Cell on May 01, 1982
Hepatitis B virus transcription in the infected liver. EMBO J (1984) 3.44
Transcription of hepatitis B virus by RNA polymerase II. Mol Cell Biol (1983) 2.81
Mapping of the cohesive overlap of duck hepatitis B virus DNA and of the site of initiation of reverse transcription. J Virol (1984) 2.72
A domain of the hepadnavirus capsid protein is specifically required for DNA maturation and virus assembly. J Virol (1991) 2.19
Hepatitis B virus infection of adult human hepatocytes cultured in the presence of dimethyl sulfoxide. J Virol (1988) 2.11
Rapid purification of hepatitis B virus DNA from serum. J Clin Microbiol (1991) 1.97
Cloned duck hepatitis B virus DNA is infectious in Pekin ducks. J Virol (1984) 1.80
Characterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formation. J Virol (2007) 1.80
Closed circular viral DNA and asymmetrical heterogeneous forms in livers from animals infected with ground squirrel hepatitis virus. J Virol (1983) 1.79
The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J Virol (1995) 1.72
Low dynamic state of viral competition in a chronic avian hepadnavirus infection. J Virol (2000) 1.66
The cloned genome of ground squirrel hepatitis virus is infectious in the animal. Proc Natl Acad Sci U S A (1984) 1.60
Formation of hepatitis B virus covalently closed circular DNA: removal of genome-linked protein. J Virol (2007) 1.51
Evidence of extrachromosomal forms of hepatitis B viral DNA in a bone marrow culture obtained from a patient recently infected with hepatitis B virus. Proc Natl Acad Sci U S A (1984) 1.32
Structure of the hepatitis B virus genome. J Virol (1983) 1.27
Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver. Proc Natl Acad Sci U S A (2003) 1.22
Infection initiated by the RNA pregenome of a DNA virus. J Virol (1991) 1.09
In vitro infection of human hepatoma (HepG2) cells with hepatitis B virus. J Virol (1990) 1.09
Hepatitis B virus infection and primary hepatocellular carcinoma. Clin Microbiol Rev (1992) 1.04
Duck hepatitis B virus replicates in the yolk sac of developing embryos. J Virol (1987) 1.04
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Age-related differences in amplification of covalently closed circular DNA at early times after duck hepatitis B virus infection of ducks. J Virol (2005) 0.91
Comparison of anti-hepatitis B virus activities of lamivudine and clevudine by a quantitative assay. Antimicrob Agents Chemother (2003) 0.83
Serum hepatitis B viral DNA in HBsAg-positive hepatocellular carcinoma treated with interferon or adriamycin. Br J Cancer (1986) 0.78
Hepatitis B virus infection. Current concepts of chronicity and immunity. West J Med (1984) 0.78
Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsies and post-mortem tissue specimens. N Engl J Med (1981) 3.17
Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell line. Nature (1980) 2.72
Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix. Proc Natl Acad Sci U S A (1984) 2.64
Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine. Am J Pathol (1998) 2.62
Isolation and partial characterization of reticulocyte factors M1 and M2. J Biol Chem (1970) 2.59
Fast skeletal muscle myosin light chains 1 and 3 are produced from a single gene by a combined process of differential RNA transcription and splicing. J Biol Chem (1984) 2.49
Analysis of liver disease, nuclear HBcAg, viral replication, and hepatitis B virus DNA in liver and serum of HBeAg Vs. anti-HBe positive carriers of hepatitis B virus. Hepatology (1983) 2.36
Factors for the initiation of haemoglobin synthesis by rabbit reticulocyte ribosomes. Nature (1970) 2.27
Hepatitis B virus DNA contains a glucocorticoid-responsive element. Proc Natl Acad Sci U S A (1986) 2.18
Thymosin treatment of chronic hepatitis B: a placebo-controlled pilot trial. Hepatology (1991) 2.15
Detection of hepatitis B virus DNA directly in human serum by a simplified molecular hybridization test: comparison to HBeAg/anti-HBe status in HBsAg carriers. Hepatology (1983) 2.10
Evidence for role of m7G5'-phosphate group in recognition of eukaryotic mRNA by initiation factor IF-M3. Nature (1976) 2.09
Alpha-tropomyosin gene organization. Alternative splicing of duplicated isotype-specific exons accounts for the production of smooth and striated muscle isoforms. J Biol Chem (1987) 1.96
Chronic type B hepatitis and the "healthy" HBsAg carrier state. Hepatology (1987) 1.94
A characterization of globin mRNA sequences in the nucleus of duck immature red blood cells. Cell (1977) 1.89
Activation, proliferation, and differentiation of progenitor cells into hepatocytes in the D-galactosamine model of liver regeneration. Am J Pathol (1993) 1.88
Identification of integrated hepatitis B virus DNA sequences in human hepatocellular carcinomas. Hepatology (1981) 1.73
Unusual ribosomal RNA of the intestinal parasite Giardia lamblia. Nucleic Acids Res (1987) 1.58
Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats. J Biol Chem (1991) 1.52
Deletion in chromosome 11p associated with a hepatitis B integration site in hepatocellular carcinoma. Science (1985) 1.51
Differentiation of pancreatic epithelial progenitor cells into hepatocytes following transplantation into rat liver. Proc Natl Acad Sci U S A (1997) 1.51
Relation of the hepatitis B virus carrier state to hepatocellular carcinoma. Hepatology (1987) 1.45
Activity of the anthelmintic benzimidazoles against Giardia lamblia in vitro. J Infect Dis (1990) 1.43
Outcome of perinatal hepatitis B virus exposure is dependent on maternal virus load. J Infect Dis (1994) 1.41
Factor dependent binding of methionyl-tRNAs to reticulocyte ribosomes. Nature (1970) 1.41
Use of electroporation to introduce biologically active foreign genes into primary rat hepatocytes. Mol Cell Biol (1986) 1.37
Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications. J Cell Biol (1987) 1.35
The glucocorticoid receptor recognizes a specific nucleotide sequence in hepatitis B virus DNA causing increased activity of the HBV enhancer. Virology (1988) 1.34
Requirement for GTP in the initiation process on reticulocyte ribosomes and ribosomal subunits. Proc Natl Acad Sci U S A (1971) 1.32
Studies on T3-induced ribonucleic acid polymerase. 3. Purification and characterization of the T3-induced ribonucleic acid polymerase from bacteriophage T3-infected Escherichia coli cells. J Biol Chem (1973) 1.28
Liver regeneration and alpha-fetoprotein messenger RNA expression in the retrorsine model for hepatocyte transplantation. Cancer Res (1998) 1.24
Monoclonal radioimmunoassays for hepatitis B surface antigen: demonstration of hepatitis B virus DNA or related sequences in serum and viral epitopes in immune complexes. Proc Natl Acad Sci U S A (1982) 1.23
Spontaneous combined hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive hypertensive rats transgenic for human cholesteryl ester transfer protein. Nat Med (1999) 1.22
Proliferation and differentiation of fetal liver epithelial progenitor cells after transplantation into adult rat liver. Am J Pathol (2000) 1.20
Comparison of alpha-tropomyosin sequences from smooth and striated muscle. Nature (1985) 1.19
Models for hepatic progenitor cell activation. Proc Soc Exp Biol Med (1993) 1.19
Puromycin-peptide bond formation with reticulocyte initiation factors M1 and M2. Proc Natl Acad Sci U S A (1971) 1.19
Prenatal malnutrition-induced changes in blood pressure: dissociation of stress and nonstress responses using radiotelemetry. Hypertension (1998) 1.19
Genetic variation during lytic reovirus infection: high-passage stocks of wild-type reovirus contain temperature-sensitive mutants. J Virol (1980) 1.18
Stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cells. Am J Pathol (2001) 1.18
Principles of therapeutic liver repopulation. Semin Liver Dis (1999) 1.17
Massive liver replacement by transplanted hepatocytes in the absence of exogenous growth stimuli in rats treated with retrorsine. Am J Pathol (2001) 1.17
Fidelity of in vitro transcription of T3 deoxyribonucleic acid by bacteriophage T3-induced ribonucleic acid polymerase and by Escherichia coli ribonucleic acid polymerase. J Biol Chem (1974) 1.16
Alpha interferon suppresses hepatitis B virus enhancer activity and reduces viral gene transcription. J Virol (1990) 1.15
A complex between initiation factor IF2, guanosine triphosphate, and fMet-tRNA: an intermediate in initiation complex formation. Proc Natl Acad Sci U S A (1971) 1.15
Distribution of rat liver albumin mRNA membrane-bound and free in polyribosomes as determined by molecular hybridization. Proc Natl Acad Sci U S A (1977) 1.14
Initial dipeptide formation in hemoglobin biosynthesis. Proc Natl Acad Sci U S A (1971) 1.13
Transcriptional switch from albumin to alpha-fetoprotein and changes in transcription of other genes during carbon tetrachloride induced liver regeneration. Biochemistry (1986) 1.11
Changing patterns of transcriptional and post-transcriptional control of liver-specific gene expression during rat development. Genes Dev (1987) 1.10
Immunotherapy in nude mice of human hepatoma using monoclonal antibodies against hepatitis B virus. Nature (1982) 1.09
Interaction of poly(A) and mRNA with eukaryotic initiator met-tRNA-f binding factor: identification of this activity on reticulocyte ribonucleic acid protein particles. Proc Natl Acad Sci U S A (1975) 1.09
Role in nude mice of interferon and natural killer cells in inhibiting the tumorigenicity of human hepatocellular carcinoma cells infected with hepatitis B virus. J Clin Invest (1983) 1.09
Identification and characterization of messenger ribonucleoprotein complexes from vesicular stomatitis virus-infected HeLa cells. Virology (1977) 1.08
Separation of two factors, M1 and M2, required for poly U dependent polypeptide synthesis by rabbit reticulocyte ribosomes at low magnesium ion concentration. Biochem Biophys Res Commun (1970) 1.08
Chronic hepatitis in chimpanzee carriers of hepatitis B virus: morphologic, immunologic, and viral DNA studies. Proc Natl Acad Sci U S A (1980) 1.07
Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata. J Cell Biol (1983) 1.07
Effect of a short term fast on the distribution of cytoplasmic albumin messenger ribonucleic acid in rat liver. Evidence for formation of free albumin messenger ribonucleoprotein particles. J Biol Chem (1978) 1.07
Initiation activity of EMC virus RNA, binding to initiation factor eIF-4B and shut-off of host cell protein synthesis. Nature (1978) 1.06
Identification of a high molecular weight presumptive precursor to albumin mRNA in the nucleus of rat liver and hepatoma cell line H4AZC2. J Biol Chem (1978) 1.05
Liver disease activity and hepatitis B virus replication in chronic delta antigen-positive hepatitis B virus carriers. Hepatology (1985) 1.05
Heat shock and stress response in Giardia lamblia. Mol Biochem Parasitol (1988) 1.05
Exon skipping during splicing of albumin mRNA precursors in Nagase analbuminemic rats. Proc Natl Acad Sci U S A (1990) 1.05
Cloning and tissue distribution of rat heart fatty acid binding protein mRNA: identical forms in heart and skeletal muscle. Biochemistry (1987) 1.04
Interrupted replication of hepatitis B virus in liver tissue of HBsAg carriers with hepatocellular carcinoma. Virology (1988) 1.02
Development and use of a rat albumin cDNA clone to evaluate the effect of chronic ethanol administration on hepatic protein synthesis. Hepatology (1983) 1.02
Cell transplantation causes loss of gap junctions and activates GGT expression permanently in host liver. Am J Physiol Gastrointest Liver Physiol (2000) 1.02
Evidence for nontranslated messenger fibonucleic acid in membrane-bound and free polysomes of rabbit liver. J Biol Chem (1974) 1.02
The alpha1 Na,K-ATPase gene is a susceptibility hypertension gene in the Dahl salt-sensitiveHSD rat. J Clin Invest (1998) 1.01
Isolation of protein synthesis initiation factors from rabbit liver. J Biol Chem (1973) 1.01
Distribution of albumin and alpha-fetoprotein mRNAs in normal, hyperplastic, and preneoplastic rat liver. Am J Pathol (1992) 1.00
Isoform-specific modulation of Na+, K+-ATPase alpha-subunit gene expression in hypertension. Science (1988) 1.00
Further characterization of bacteriophage T3-induced ribonucleic acid polymerase. Studies on the size of in vitro transcripts and interaction of T3 RNA polymerase with T3 DNA. J Biol Chem (1977) 0.99
Selecting binding and complement-mediated lysis of human hepatoma cells (PLC/PRF/5) in culture by monoclonal antibodies to hepatitis B surface antigen. Proc Natl Acad Sci U S A (1982) 0.99
Tumorigenicity in nude mice of a human hepatoma cell line containing hepatitis B virus DNA. Cancer Res (1981) 0.99
Changes in collagen and albumin mRNA in liver tissue of mice infected with Schistosoma mansoni as determined by in situ hybridization. J Cell Biol (1983) 0.99
Phyllanthus amarus down-regulates hepatitis B virus mRNA transcription and replication. Eur J Clin Invest (1996) 0.98
Differentiation-specific regulation of transgene expression in a diploid epithelial cell line derived from the normal F344 rat liver. J Pathol (1999) 0.97
Use of molecular hybridization to purify and analyze albumin messenger RNA from rat liver. Proc Natl Acad Sci U S A (1977) 0.97
Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression. Am J Physiol (1994) 0.97
Albumin gene expression is down-regulated by albumin or macromolecule infusion in the rat. J Clin Invest (1992) 0.97
Separation of reticulocyte initiation factor M 2 activity into two components. Proc Natl Acad Sci U S A (1972) 0.97
Evidence for unusually short tubulin mRNA leaders and characterization of tubulin genes in Giardia lamblia. Mol Biochem Parasitol (1989) 0.97
A novel system for transplantation of isolated hepatocytes utilizing HBsAg-producing transgenic donor cells. Transplantation (1990) 0.96
Cross-protection against four species of chicken coccidia with a single recombinant antigen. Infect Immun (1991) 0.94
Widespread differentiation stage-specific expression of the gene encoding phosphoprotein p19 (metablastin) in mammalian cells. Differentiation (1992) 0.94
Restoration of serum albumin levels in nagase analbuminemic rats by hepatocyte transplantation. Hepatology (1999) 0.93
Comparative morphology and tumourigenicity of human hepatocellular carcinoma cell lines in athymic rats and mice. Virchows Arch A Pathol Anat Histopathol (1988) 0.92
Cloning and sequence of beta tubulin cDNA from Giardia lamblia. Nucleic Acids Res (1988) 0.92
Role of thyroid hormone in stimulating liver repopulation in the rat by transplanted hepatocytes. Hepatology (1999) 0.91
Use of in situ hybridization to identify collagen and albumin mRNAs in isolated mouse hepatocytes. Proc Natl Acad Sci U S A (1983) 0.91
Variants of hepatitis B virus associated with fulminant liver disease. N Engl J Med (1991) 0.91