Published in J Mol Biol on August 25, 1982
A new insertion sequence, IS121, is found on the Mu dI1 (Ap lac) bacteriophage and the Escherichia coli K-12 chromosome. J Bacteriol (1983) 2.25
Structural requirement for IS50-mediated gene transposition. Proc Natl Acad Sci U S A (1983) 1.96
recA-independent recombination between repeated IS50 elements is not caused by an IS50-encoded function. J Bacteriol (1985) 1.10
Transposition of IS50L activates downstream genes. J Bacteriol (1988) 1.08
DNA length, bending, and twisting constraints on IS50 transposition. Proc Natl Acad Sci U S A (1994) 1.05
The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature (1997) 34.00
DNAse footprinting: a simple method for the detection of protein-DNA binding specificity. Nucleic Acids Res (1978) 30.43
Insertion sequences. Microbiol Mol Biol Rev (1998) 14.03
ISfinder: the reference centre for bacterial insertion sequences. Nucleic Acids Res (2006) 9.58
Transposition of R factor genes to bacteriophage lambda. Proc Natl Acad Sci U S A (1975) 9.28
DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting. Nucleic Acids Res (1992) 8.86
Polarity of Tn5 insertion mutations in Escherichia coli. J Bacteriol (1980) 7.55
Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging. Science (1998) 6.99
A simple method for site-directed mutagenesis using the polymerase chain reaction. Nucleic Acids Res (1989) 6.78
Genome sequence of the plant pathogen Ralstonia solanacearum. Nature (2002) 6.23
The interaction of RNA polymerase and lac repressor with the lac control region. Nucleic Acids Res (1979) 6.17
Granulation tissue as a contractile organ. A study of structure and function. J Exp Med (1972) 5.42
Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol (1998) 5.07
Rapid, efficient detection and drug susceptibility testing of Mycobacterium tuberculosis in sputum by microscopic observation of broth cultures. The Tuberculosis Working Group in Peru. J Clin Microbiol (2000) 5.01
Rigorous pattern-recognition methods for DNA sequences. Analysis of promoter sequences from Escherichia coli. J Mol Biol (1985) 4.95
Recombination and clonal groupings within Helicobacter pylori from different geographical regions. Mol Microbiol (1999) 4.72
Nomenclature of transposable elements in prokaryotes. Gene (1979) 4.13
Two pathogenicity islands in uropathogenic Escherichia coli J96: cosmid cloning and sample sequencing. Infect Immun (1996) 3.89
A controlled trial of zidovudine in primary human immunodeficiency virus infection. N Engl J Med (1995) 3.89
Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase. Mol Microbiol (1998) 3.44
Differences in genotypes of Helicobacter pylori from different human populations. J Bacteriol (2000) 3.39
Contraction of granulation tissue in vitro: similarity to smooth muscle. Science (1971) 3.29
Emergence of recombinant strains of Helicobacter pylori during human infection. Mol Microbiol (1999) 3.25
RAPD (arbitrary primer) PCR is more sensitive than multilocus enzyme electrophoresis for distinguishing related bacterial strains. Nucleic Acids Res (1993) 3.10
Functional similarities between retroviruses and the IS3 family of bacterial insertion sequences? Mol Microbiol (1990) 3.08
Specificity of transposon Tn5 insertion. Genetics (1983) 3.04
Epithelial attachment alters the outcome of Helicobacter pylori infection. Proc Natl Acad Sci U S A (1998) 2.96
PCR-based subtractive hybridization and differences in gene content among strains of Helicobacter pylori. Proc Natl Acad Sci U S A (1998) 2.93
Ordered cosmid library and high-resolution physical-genetic map of Helicobacter pylori strain NCTC11638. Mol Microbiol (1994) 2.93
Long-term colonization with single and multiple strains of Helicobacter pylori assessed by DNA fingerprinting. J Clin Microbiol (1995) 2.88
Sequence analysis of Tn9 insertions in the lacZ gene. J Mol Biol (1980) 2.85
Distinctiveness of genotypes of Helicobacter pylori in Calcutta, India. J Bacteriol (2000) 2.81
Escherichia coli integration host factor bends the DNA at the ends of IS1 and in an insertion hotspot with multiple IHF binding sites. EMBO J (1987) 2.74
Transposition in Shigella dysenteriae: isolation and analysis of IS911, a new member of the IS3 group of insertion sequences. J Bacteriol (1990) 2.63
PCR-based RFLP analysis of DNA sequence diversity in the gastric pathogen Helicobacter pylori. Nucleic Acids Res (1992) 2.62
Excision of transposon Tn5 is dependent on the inverted repeats but not on the transposase function of Tn5. Proc Natl Acad Sci U S A (1981) 2.59
Helicobacter pylori genetic diversity and risk of human disease. J Clin Invest (2001) 2.58
Diversity among clinical isolates of Histoplasma capsulatum detected by polymerase chain reaction with arbitrary primers. J Bacteriol (1992) 2.54
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms. J Biol Chem (1979) 2.53
Restriction enzyme cleavage map of Tn10, a transposon which encodes tetracycline resistance. J Bacteriol (1979) 2.51
Cointegrate formation mediated by Tn9. II. Activity of IS1 is modulated by external DNA sequences. J Mol Biol (1983) 2.45
Insertion, excision, and inversion of Tn5. Cold Spring Harb Symp Quant Biol (1981) 2.37
Use of gel retardation to analyze protein-nucleic acid interactions. Microbiol Rev (1992) 2.35
Tn5tac1, a derivative of transposon Tn5 that generates conditional mutations. Proc Natl Acad Sci U S A (1988) 2.34
Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori? Trends Microbiol (1997) 2.33
Integrating DNA: transposases and retroviral integrases. Annu Rev Microbiol (1999) 2.27
IS50-mediated inverse transposition. Discrimination between the two ends of an IS element. J Mol Biol (1982) 2.26
Escherichia coli integration host factor binds specifically to the ends of the insertion sequence IS1 and to its major insertion hot-spot in pBR322. J Mol Biol (1987) 2.17
Nomenclature of transposable elements in prokaryotes. Plasmid (1979) 2.17
Prevalence of vacuolating cytotoxin production and distribution of distinct vacA alleles in Helicobacter pylori from China. J Infect Dis (1998) 2.09
Bacterial transposases and retroviral integrases. Mol Microbiol (1995) 2.00
The replication time of the Escherichia coli K12 chromosome as a function of cell doubling time. J Mol Biol (1975) 1.98
Replication of pSC101: effects of mutations in the E. coli DNA binding protein IHF. Mol Gen Genet (1986) 1.98
Host specificity of Helicobacter pylori strains and host responses in experimentally challenged nonhuman primates. Gastroenterology (1999) 1.96
Pattern recognition in several sequences: consensus and alignment. Bull Math Biol (1984) 1.96
Sequences essential for transposition at the termini of IS50. Proc Natl Acad Sci U S A (1983) 1.96
Structural requirement for IS50-mediated gene transposition. Proc Natl Acad Sci U S A (1983) 1.96
Bidirectional chain-termination nucleotide sequencing: transposon Tn5seq1 as a mobile source of primer sites. Gene (1988) 1.95
Variability in antihypertensive drug costs. N Z Med J (1989) 1.95
Structure and stability of Tn9-mediated cointegrates. Evidence for two pathways of transposition. J Mol Biol (1982) 1.90
Replication of prophage P1 during the cell cycle of Escherichia coli. Mol Gen Genet (1977) 1.89
cysQ, a gene needed for cysteine synthesis in Escherichia coli K-12 only during aerobic growth. J Bacteriol (1992) 1.86
Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (Nitroreductase) gene. J Bacteriol (2000) 1.83
Programmed translational frameshifting and initiation at an AUU codon in gene expression of bacterial insertion sequence IS911. J Mol Biol (1991) 1.82
Transient and persistent experimental infection of nonhuman primates with Helicobacter pylori: implications for human disease. Infect Immun (1996) 1.81
Comparison of arbitrarily primed PCR and macrorestriction (pulsed-field gel electrophoresis) typing of Pseudomonas aeruginosa strains from cystic fibrosis patients. J Clin Microbiol (1995) 1.79
On the molecular mechanisms of transposition. Proc Natl Acad Sci U S A (1981) 1.77
Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori. J Bacteriol (2000) 1.77
Genetic evidence for two types of gene arrangements in new lambdadv plasmid mutants. J Mol Biol (1974) 1.76
Transposable elements for efficient manipulation of a wide range of gram-negative bacteria: promoter probes and vectors for foreign genes. Gene (1989) 1.76
Characterization of VPI pathogenicity island and CTXphi prophage in environmental strains of Vibrio cholerae. J Bacteriol (2001) 1.76
IS1-mediated intramolecular rearrangements: formation of excised transposon circles and replicative deletions. EMBO J (1995) 1.76
Novel sequence organization and insertion specificity of IS605 and IS606: chimaeric transposable elements of Helicobacter pylori. Gene (1998) 1.71
Identification of base pairs in the outside end of insertion sequence IS50 that are needed for IS50 and Tn5 transposition. Proc Natl Acad Sci U S A (1987) 1.70
Direct and crossover PCR amplification to facilitate Tn5supF-based sequencing of lambda phage clones. Nucleic Acids Res (1991) 1.68
Local DNA sequence control of deletion formation in Escherichia coli plasmid pBR322. Genetics (1987) 1.67
Factors affecting transposition activity of IS50 and Tn5 ends. Gene (1989) 1.67
Conceptual framework and systematic review of the effects of participants' and professionals' preferences in randomised controlled trials. Health Technol Assess (2005) 1.65
Inverted repeats of Tn5 are transposable elements. Proc Natl Acad Sci U S A (1982) 1.64
Functional promoters created by the insertion of transposable element IS1. J Mol Biol (1986) 1.64
Use of arbitrarily primed polymerase chain reaction analysis to type disease and carrier strains of Neisseria meningitidis isolated during a university outbreak. J Infect Dis (1994) 1.63
The effects of an Escherichia coli dnaAts mutation on the replication of the plasmids colE1 pSC101, R100.1 and RTF-TC. Mol Gen Genet (1979) 1.62
Transposase-induced excision and circularization of the bacterial insertion sequence IS911. EMBO J (1992) 1.62
Formation of supercoiling domains in plasmid pBR322. J Bacteriol (1989) 1.62
The gene for a tRNA modifying enzyme, m5U54-methyltransferase, is essential for viability in Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.61
Expression of proteins essential for IS1 transposition: specific binding of InsA to the ends of IS1. EMBO J (1987) 1.61
Tests of reciprocality in crossingover in partially diploid F strains of Escherichia coli. Genetics (1971) 1.60
The transposition frequency of IS1-flanked transposons is a function of their size. J Mol Biol (1982) 1.59
Efficient introduction of cloned mutant alleles into the Escherichia coli chromosome. J Bacteriol (1991) 1.58
The structure of R1drd19: a revised physical map of the plasmid. Mol Gen Genet (1981) 1.53
IS elements as constituents of bacterial genomes. Res Microbiol (2000) 1.52