Published in FEBS Lett on September 19, 1983
The reconstituted isolated uncoupling protein is a membrane potential driven H+ translocator. EMBO J (1985) 1.18
Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA. Biochem J (1986) 1.11
The mitochondrial uncoupling protein from guinea-pig brown adipose tissue. Synchronous increase in structural and functional parameters during cold-adaptation. Biochem J (1984) 1.01
Factors influencing the altered thermogenic response of rat brown adipose tissue in streptozotocin-diabetes. Biochem J (1988) 0.99
Evidence for unmasking of rat brown-adipose-tissue mitochondrial GDP-binding sites in response to acute cold exposure. Effects of washing with albumin on GDP binding. Biochem J (1986) 0.95
Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation. Proc Natl Acad Sci U S A (2015) 0.91
Evidence for decreased GDP binding to brown-adipose-tissue mitochondria of obese Zucker (fa/fa) rats in the very first days of life. Biochem J (1984) 0.90
Mapping the nucleotide binding site of uncoupling protein 1 using atomic force microscopy. J Am Chem Soc (2013) 0.81
Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria. Biochem J (1985) 0.77
Effects of hypothyroidism and hyperthyroidism on GDP binding to brown-adipocyte mitochondria from rats. Biochem J (1989) 0.76
Thermogenic mechanisms in brown fat. Physiol Rev (1984) 5.34
The influence of respiration and ATP hydrolysis on the proton-electrochemical gradient across the inner membrane of rat-liver mitochondria as determined by ion distribution. Eur J Biochem (1974) 4.70
[The relationship between palmitoyl-coenzyme A synthetase activity and esterification of sn-glycerol 3-phosphate in rat liver mitochondria]. Biochem J (1973) 2.71
Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ. Biochem J (1980) 2.71
The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria. Biochem J (1978) 2.65
A reevaluation of the role of mitochondria in neuronal Ca2+ homeostasis. J Neurochem (1996) 2.32
Determination of the mitochondrial protonmotive force in isolated hepatocytes. J Biol Chem (1980) 2.00
Brown adipose tissue mitochondria. Biochim Biophys Acta (1979) 1.93
Mitochondrial calcium transport. FEBS Lett (1980) 1.93
Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem (1996) 1.85
Brown-adipose-tissue mitochondria: photoaffinity labelling of the regulatory site of energy dissipation. Eur J Biochem (1978) 1.80
Calcium-ion transport by intact synaptosomes. Intrasynaptosomal compartmentation and the role of the mitochondrial membrane potential. Biochem J (1980) 1.76
'Mild Uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress. J Neurochem (2007) 1.76
Mitochondrial membrane potential and hydroethidine-monitored superoxide generation in cultured cerebellar granule cells. FEBS Lett (1997) 1.74
Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci (2000) 1.66
Transmembrane electrical potential and transmembrane pH gradient in the acidophile Thiobacillus ferro-oxidans. Biochem J (1979) 1.65
Hamster brown-adipose-tissue mitochondria. Purine nucleotide control of the ion conductance of the inner membrane, the nature of the nucleotide binding site. Eur J Biochem (1976) 1.58
Calcium-dependent and -independent release of glutamate from synaptosomes monitored by continuous fluorometry. J Neurochem (1987) 1.58
Calcium transport and porton electrochemical potential gradient in mitochondria from guinea-pig cerebral cortex and rat heart. Biochem J (1978) 1.54
Synaptosomes possess an exocytotic pool of glutamate. Nature (1986) 1.54
A continuous recording technique for the measurement of carbon dioxide, and its application to mitochondrial oxidation and decarboxylation reactions. Biochem J (1967) 1.53
Hamster brown-adipose-tissue mitochondria. The control of respiration and the proton electrochemical potential gradient by possible physiological effectors of the proton conductance of the inner membrane. Eur J Biochem (1974) 1.50
Tetanus toxin and botulinum toxins type A and B inhibit glutamate, gamma-aminobutyric acid, aspartate, and met-enkephalin release from synaptosomes. Clues to the locus of action. J Biol Chem (1992) 1.43
Differential release of amino acids, neuropeptides, and catecholamines from isolated nerve terminals. Neuron (1991) 1.41
The calcium conductance of the inner membrane of rat liver mitochondria and the determination of the calcium electrochemical gradient. Biochem J (1976) 1.39
A history of the first uncoupling protein, UCP1. J Bioenerg Biomembr (1999) 1.37
The characterization and energetic potential of brown adipose tissue in man. Clin Sci (Lond) (1985) 1.30
Synaptosomal bioenergetics. The role of glycolysis, pyruvate oxidation and responses to hypoglycaemia. Eur J Biochem (1986) 1.27
The effective proton conductance of the inner membrane of mitochondria from brown adipose tissue. Dependency on proton electrochemical potential gradient. Eur J Biochem (1977) 1.27
Synaptic vesicle recycling in cultured cerebellar granule cells: role of vesicular acidification and refilling. J Neurochem (1997) 1.27
Brown-adipose-tissue mitochondria: the regulation of the 32000-Mr uncoupling protein by fatty acids and purine nucleotides. Eur J Biochem (1983) 1.24
The regulation of brain mitochondrial calcium-ion transport. The role of ATP in the discrimination between kinetic and membrane-potential-dependent calcium-ion efflux mechanisms. Biochem J (1980) 1.23
The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation of endogenous nicotinamide nucleotides. Biochem J (1980) 1.20
Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts. Aging Cell (2003) 1.19
The identification of the component in the inner membrane of brown adipose tissue mitochondria responsible for regulating energy dissipation. Experientia Suppl (1978) 1.13
Fatty acids as acute regulators of the proton conductance of hamster brown-fat mitochondria. Eur J Biochem (1982) 1.13
Repetitive action potentials in isolated nerve terminals in the presence of 4-aminopyridine: effects on cytosolic free Ca2+ and glutamate release. J Neurochem (1989) 1.12
Localized Ca2+ entry preferentially effects protein dephosphorylation, phosphorylation, and glutamate release. J Biol Chem (1992) 1.10
Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci (1998) 1.08
Cysteine residues are not essential for uncoupling protein function. Biochem J (1993) 1.07
Transmitter glutamate release from isolated nerve terminals: evidence for biphasic release and triggering by localized Ca2+. J Neurochem (1991) 1.07
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells. J Neurosci (1990) 1.07
Unequal charge separation by different coupling spans of the mitochondrial electron transport chain. FEBS Lett (1978) 1.06
alpha-latrotoxin of black widow spider venom depolarizes the plasma membrane, induces massive calcium influx, and stimulates transmitter release in guinea pig brain synaptosomes. Proc Natl Acad Sci U S A (1982) 1.04
A role for the mitochondrion in the protection of cells against calcium overload? Prog Brain Res (1985) 1.04
A sequence related to a DNA recognition element is essential for the inhibition by nucleotides of proton transport through the mitochondrial uncoupling protein. EMBO J (1994) 1.03
Intrasynaptosomal compartmentation of calcium during depolarization-induced calcium uptake across the plasma membrane. Biochim Biophys Acta (1981) 1.03
Effect of trypsin on mitochondrial and microsomal enzymes. Eur J Biochem (1970) 1.01
The mitochondrial uncoupling protein from guinea-pig brown adipose tissue. Synchronous increase in structural and functional parameters during cold-adaptation. Biochem J (1984) 1.01
Brown-adipose-tissue mitochondria. The influence of albumin and nucleotides on passive ion permeabilities. Eur J Biochem (1973) 1.00
Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates. Biochim Biophys Acta (1987) 1.00
Bioenergetic analysis of cerebellar granule neurons undergoing apoptosis by potassium/serum deprivation. Cell Death Differ (2006) 0.99
The bioenergetics of brown adipose tissue mitochondria. FEBS Lett (1976) 0.99
The mechanism of mitochondrial membrane potential retention following release of cytochrome c in apoptotic GT1-7 neural cells. Cell Death Differ (2001) 0.98
Biochemical approaches to the study of cytosolic calcium regulation in nerve endings. Philos Trans R Soc Lond B Biol Sci (1981) 0.96
The bioenergetics of neurotransmitter release. Biochim Biophys Acta (1991) 0.95
Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem (1999) 0.95
Presynaptic receptors and the control of glutamate exocytosis. Trends Neurosci (1996) 0.94
The mitochondrial uncoupling protein UCP1: a gated pore. IUBMB Life (2002) 0.94
Hamster brown-adipose-tissue mitochondria. The chloride permeability of the inner membrane under respiring conditions, the influence of purine nucleotides. Eur J Biochem (1974) 0.93
Glutamate exocytosis and MARCKS phosphorylation are enhanced by a metabotropic glutamate receptor coupled to a protein kinase C synergistically activated by diacylglycerol and arachidonic acid. J Neurochem (1994) 0.92
Mitochondrial from hamster brown-adipose tissue. Regulation of respiration in vitro by variations in volume of the matrix compartment. Eur J Biochem (1972) 0.92
Activation by ATP of a proton-conducting pathway in yeast mitochondria. Eur J Biochem (1992) 0.92
Intracellular calcium homeostasis. Br Med Bull (1986) 0.92
Expression and regulation of mitochondrial uncoupling protein 1 from brown adipose tissue in Leishmania major promastigotes. Mol Biochem Parasitol (1998) 0.91
Density gradient separation of human platelets from plasma and the role of plasma in adenosine diphosphate induced platelet electrophoretic mobility changes. Thromb Diath Haemorrh (1972) 0.91
Ca2+ transport by intact synaptosomes: the voltage-dependent Ca2+ channel and a re-evaluation of the role of sodium/calcium exchange. Eur J Biochem (1981) 0.91
The uncoupling protein UCP1 does not increase the proton conductance of the inner mitochondrial membrane by functioning as a fatty acid anion transporter. J Biol Chem (1998) 0.91
Energy-dependent control of the tricarboxylic acid cycle by fatty acid oxidation in rat liver mitochondria. Adv Enzyme Regul (1968) 0.90
An ion channel locus for the protein kinase C potentiation of transmitter glutamate release from guinea pig cerebrocortical synaptosomes. J Neurochem (1991) 0.90
The uncoupling protein from brown-adipose-tissue mitochondria. Chymotrypsin-induced structural and functional modifications. Eur J Biochem (1987) 0.89
Protein kinase C-mediated suppression of the presynaptic adenosine A1 receptor by a facilitatory metabotropic glutamate receptor. J Neurochem (1995) 0.89
The acute regulation of mitochondrial proton conductance in cells and mitochondria from the brown fat of cold-adapted and warm-adapted guinea pigs. Eur J Biochem (1982) 0.89
A ligand-receptor pair that triggers a non-apoptotic form of programmed cell death. Cell Death Differ (2002) 0.89
Dendrotoxin, 4-aminopyridine, and beta-bungarotoxin act at common loci but by two distinct mechanisms to induce Ca2+-dependent release of glutamate from guinea-pig cerebrocortical synaptosomes. J Neurochem (1989) 0.88
Involvement of calcium influx in muscarinic cholinergic regulation of phospholipase C in cerebellar granule cells. J Neurochem (1994) 0.88
Characterization of the exocytotic release of glutamate from guinea-pig cerebral cortical synaptosomes. J Neurochem (1987) 0.87
Quantification of fatty acid activation of the uncoupling protein in brown adipocytes and mitochondria from the guinea-pig. Eur J Biochem (1986) 0.87
Pyruvate utilization by synaptosomes is independent of calcium. FEBS Lett (1986) 0.87
Mitochondria control ampa/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells. J Neurosci (2001) 0.87
Interactions between phospholipase C-coupled and N-methyl-D-aspartate receptors in cultured cerebellar granule cells: protein kinase C mediated inhibition of N-methyl-D-aspartate responses. J Neurochem (1992) 0.86
The nature and regulation of the ATP-induced anion permeability in Saccharomyces cerevisiae mitochondria. Arch Biochem Biophys (1996) 0.86
Glutamate release from guinea-pig synaptosomes: stimulation by reuptake-induced depolarization. J Neurochem (1989) 0.86
Permeabilization of the mitochondrial inner membrane by short cecropin-A-melittin hybrid peptides. Eur J Biochem (1994) 0.85
Rosiglitazone up-regulates lipoprotein lipase, hormone-sensitive lipase and uncoupling protein-1, and down-regulates insulin-induced fatty acid synthase gene expression in brown adipocytes of Wistar rats. Diabetologia (2005) 0.85
The estimation of the electrical potential across the inner membrane of mitochondria within intact synaptosomes [proceedings]. Biochem Soc Trans (1979) 0.84
Alpha-latrotoxin releases both vesicular and cytoplasmic glutamate from isolated nerve terminals. J Neurochem (1990) 0.84
Failure to maintain glycolysis in anoxic nerve terminals. J Neurochem (1986) 0.84
Ca2+-dependent and Ca2+-independent glutamate release, energy status and cytosolic free Ca2+ concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia. Neuroscience (1988) 0.84
The mechanism for the ATP-induced uncoupling of respiration in mitochondria of the yeast Saccharomyces cerevisiae. Biochem J (1995) 0.84
Flunarizine inhibits both calcium-dependent and -independent release of glutamate from synaptosomes and cultured neurones. Brain Res (1993) 0.83