Published in J Cell Biol on December 01, 1983
Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol (1984) 4.88
Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome. J Cell Biol (1989) 3.84
Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J Cell Biol (1995) 3.03
Receptor-mediated endocytosis. Biochem J (1985) 2.73
Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway. J Cell Biol (1986) 2.37
Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pH. J Cell Biol (1987) 2.28
Sorting of endocytosed transferrin and asialoglycoprotein occurs immediately after internalization in HepG2 cells. J Cell Biol (1987) 2.25
Receptor-mediated endocytosis of asialoglycoproteins by rat hepatocytes: receptor-positive and receptor-negative endosomes. J Cell Biol (1986) 1.99
Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway. J Cell Biol (1986) 1.94
Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells. J Cell Biol (1987) 1.82
Role of vesicles during adenovirus 2 internalization into HeLa cells. J Virol (1985) 1.81
Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu. Cell Host Microbe (2010) 1.74
Two threshold values of low pH block endocytosis at different stages. EMBO J (1987) 1.69
Intracellular fusion of sequentially formed endocytic compartments. J Cell Biol (1988) 1.67
Effect of lysosomotropic amines on the secretory pathway and on the recycling of the asialoglycoprotein receptor in human hepatoma cells. J Cell Biol (1985) 1.50
Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells. J Cell Biol (1987) 1.42
Thyrotropin-releasing hormone-induced changes in intracellular [Ca2+] measured by microspectrofluorometry on individual quin2-loaded cells. J Cell Biol (1984) 1.39
Transport of a fluorescent macromolecule via endosomes to the vacuole in Saccharomyces cerevisiae. J Cell Biol (1987) 1.38
Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relationship to cell surface receptor. J Clin Invest (1986) 1.15
Ligand- and weak base-induced redistribution of asialoglycoprotein receptors in hepatoma cells. J Cell Biol (1987) 1.14
The position of lysosomes within the cell determines their luminal pH. J Cell Biol (2016) 1.13
Human IgA as a heterovalent ligand: switching from the asialoglycoprotein receptor to secretory component during transport across the rat hepatocyte. J Cell Biol (1986) 1.03
Reduced temperature alters Pseudomonas exotoxin A entry into the mouse LM cell. Infect Immun (1986) 1.00
Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region. J Cell Biol (1991) 0.98
The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole. J Cell Biol (1987) 0.97
Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin. J Cell Biol (1984) 0.93
Analysis of intracellular receptor/ligand sorting. Calculation of mean surface and bulk diffusion times within a sphere. Biophys J (1986) 0.88
The effects of monensin on secretion of very-low-density lipoprotein and metabolism of asialofetuin by cultured rat hepatocytes. Biochem J (1985) 0.87
Endocytosis of beta-adrenergic ligands by rat liver. Comparison of beta-adrenergic receptor and adenylate cyclase distribution in endosome and plasma-membrane fractions. Biochem J (1984) 0.86
Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore. Chem Commun (Camb) (2015) 0.83
A new splice variant of the major subunit of human asialoglycoprotein receptor encodes a secreted form in hepatocytes. PLoS One (2010) 0.80
A novel cycle involving fatty acyl-coenzyme A regulates asialoglycoprotein receptor activity in permeable hepatocytes. Mol Biol Cell (1994) 0.80
Quantification of polarized trafficking of transferrin and comparison with bulk membrane transport in hepatic cells. Biochem J (2006) 0.78
Iterative endocytosis of transferrin by K562 cells. Biochem J (1994) 0.76
In Vivo Analysis of the Neurovascular Niche in the Developing Xenopus Brain. eNeuro (2017) 0.75
The thiobarbituric acid assay of sialic acids. J Biol Chem (1959) 43.78
Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents. Proc Natl Acad Sci U S A (1978) 18.85
The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. Adv Enzymol Relat Areas Mol Biol (1974) 7.83
Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell (1982) 7.23
Intracellular site of asialoglycoprotein receptor-ligand uncoupling: double-label immunoelectron microscopy during receptor-mediated endocytosis. Cell (1983) 6.89
Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages. J Cell Biol (1981) 6.63
Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling. J Cell Biol (1980) 5.99
Receptor-mediated endocytosis of transferrin and the uptake of fe in K562 cells: identification of a nonlysosomal acidic compartment. Proc Natl Acad Sci U S A (1982) 5.74
Perturbation of vesicular traffic with the carboxylic ionophore monensin. Cell (1983) 5.71
Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts. Cell (1981) 5.59
Carbohydrate-specific receptors of the liver. Annu Rev Biochem (1982) 5.58
Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells. J Biol Chem (1980) 5.24
Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol (1982) 5.11
The galactose-specific recognition system of mammalian liver: the route of ligand internalization in rat hepatocytes. Cell (1980) 5.03
Low temperature selectively inhibits fusion between pinocytic vesicles and lysosomes during heterophagy of 125I-asialofetuin by the perfused rat liver. J Biol Chem (1980) 5.00
Plasma cell immunoglobulin secretion: arrest is accompanied by alterations of the golgi complex. J Exp Med (1977) 4.59
Intracellular transport of secretory and membrane proteins in hepatoma cells infected by vesicular stomatitis virus. Cell (1980) 4.15
Journey to the center of the cell: role of the receptosome. Science (1981) 4.07
Collection of insulin, EGF and alpha2-macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization. Cell (1978) 3.90
Identification and characterization of a proton pump on lysosomes by fluorescein-isothiocyanate-dextran fluorescence. Proc Natl Acad Sci U S A (1982) 3.03
Mannose-specific endocytosis receptor of alveolar macrophages: demonstration of two functionally distinct intracellular pools of receptor and their roles in receptor recycling. J Cell Biol (1982) 2.81
Fate of receptor and ligand during endocytosis of asialoglycoproteins by isolated hepatocytes. Proc Natl Acad Sci U S A (1982) 2.54
Monensin inhibits Semliki Forest virus penetration into culture cells. Proc Natl Acad Sci U S A (1982) 2.46
Intracellular dissociation of receptor-bound asialoglycoproteins in cultured hepatocytes. A pH-mediated nonlysosomal event. J Biol Chem (1983) 2.45
Primary amines inhibit recycling of alpha 2M receptors in fibroblasts. Cell (1980) 2.40
Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line. J Biol Chem (1982) 2.35
Characterization of the low density lipoprotein receptor in membranes prepared from human fibroblasts. J Biol Chem (1978) 2.24
Receptor-mediated endocytosis of diphtheria toxin by cells in culture. Proc Natl Acad Sci U S A (1982) 1.59
Monensin blocks the transport of diphtheria toxin to the cell cytoplasm. J Cell Biol (1982) 1.58
Purification of neuraminidases from Vibrio Cholerae, Clostridium Perfringens and influenza virus by affinity chromatography. Biochem Biophys Res Commun (1971) 1.48
pH changes in pinosomes and phagosomes in the ameba, Chaos carolinensis. J Cell Biol (1982) 1.43
Immunocytochemical localization of the receptor for asialoglycoprotein in rat liver cells. J Cell Biol (1982) 1.40
Endocytosis and degradation mediated by the asialoglycoprotein receptor in isolated rat hepatocytes. J Biol Chem (1982) 1.27
Partial resialylation of human asialotransferrin type 3 in the rat. Proc Natl Acad Sci U S A (1982) 1.21
Effect of primary amines on interferon action. Virology (1982) 0.98
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science (1997) 29.34
The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics. JAMA (1998) 7.81
Endocytosis. Physiol Rev (1997) 7.33
Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell (1982) 7.23
Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell (1984) 6.50
Membrane transport in the endocytic pathway. Curr Opin Cell Biol (1995) 5.86
Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells. J Biol Chem (1980) 5.24
Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol (1982) 5.11
Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J Cell Biol (1993) 5.08
Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol (1984) 4.88
Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science (1994) 4.36
Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease. Neurology (1995) 3.91
Collection of insulin, EGF and alpha2-macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization. Cell (1978) 3.90
Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome. J Cell Biol (1989) 3.84
Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor. J Cell Biol (1987) 3.28
Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature (1995) 3.22
Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells. Nat Cell Biol (2001) 3.22
Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron (1996) 3.14
Tumour-suppressor activity of H19 RNA. Nature (1993) 3.06
Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J Cell Biol (1995) 3.03
Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy. J Cell Sci (1994) 2.88
Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature (1980) 2.82
Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol Biol Cell (1995) 2.74
Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO J (1998) 2.63
Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails. J Cell Biol (1999) 2.55
alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. J Cell Biol (1979) 2.48
The apolipoprotein epsilon 4 allele in patients with Alzheimer's disease. Ann Neurol (1993) 2.48
An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. J Cell Biol (1998) 2.43
Cholesterol depletion induces large scale domain segregation in living cell membranes. Proc Natl Acad Sci U S A (2001) 2.41
Amines inhibit the clustering of alpha2-macroglobulin and EGF on the fibroblast cell surface. Nature (1979) 2.41
Direct visualization of fluorescein-labeled microtubules in vitro and in microinjected fibroblasts. J Cell Biol (1981) 2.33
Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophys J (1998) 2.30
Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes. J Cell Biol (1992) 2.24
Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells. J Cell Biol (1995) 2.19
Ca2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. J Cell Sci (2000) 2.19
Creation of genomic methylation patterns. Nat Genet (1996) 2.15
Status of empirical methods for the prediction of protein backbone topography. Biochemistry (1976) 2.12
Oriented endocytic recycling of alpha5beta1 in motile neutrophils. Blood (2000) 2.11
Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain. Cell Regul (1990) 2.09
The effect of neighboring charges on the helix forming ability of charged amino acids in proteins. Macromolecules (1976) 2.08
Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways. J Cell Biol (1999) 2.06
Characterization of rapid membrane internalization and recycling. J Biol Chem (2000) 2.03
Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. J Cell Biol (1995) 2.02
Role of membrane organization and membrane domains in endocytic lipid trafficking. Traffic (2000) 2.02
Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells. J Cell Biol (1989) 1.98
Monoallelic expression of the human H19 gene. Nat Genet (1992) 1.96
Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks. Ann Neurol (1995) 1.85
Acidification of endocytic vesicles by an ATP-dependent proton pump. J Cell Biol (1983) 1.84
Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells. J Cell Biol (1987) 1.82
A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families. JAMA (2001) 1.82
Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila. Infect Immun (1998) 1.75
Unbalanced placental expression of imprinted genes in human intrauterine growth restriction. Placenta (2005) 1.73
Sphingomyelinase treatment induces ATP-independent endocytosis. J Cell Biol (1998) 1.72
Monoallelic expression: 'there can only be one'. Trends Genet (1998) 1.72
Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix. J Leukoc Biol (1997) 1.69
Transient increases in cytosolic free calcium appear to be required for the migration of adherent human neutrophils. J Cell Biol (1990) 1.69
Local cytoplasmic calcium gradients in living mitotic cells. Nature (1985) 1.69
Intracellular fusion of sequentially formed endocytic compartments. J Cell Biol (1988) 1.67
Isolation of a temperature-sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment. J Cell Physiol (1993) 1.63
Coding mutations in p57KIP2 are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumors. Am J Hum Genet (1997) 1.62
Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation. JAMA (1997) 1.61
Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling. J Biol Chem (1997) 1.61
Receptor-mediated endocytosis of diphtheria toxin by cells in culture. Proc Natl Acad Sci U S A (1982) 1.59
The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis. Hum Mol Genet (1997) 1.56
PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer. Oncogene (2008) 1.54
The apolipoprotein epsilon 4 allele in Parkinson's disease with and without dementia. Neurology (1994) 1.54
The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected. J Cell Biol (1993) 1.54
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science (1992) 1.53
Memory performance in healthy elderly without Alzheimer's disease: effects of time and apolipoprotein-E. Neurobiol Aging (2001) 1.52
Preparation of solutions with free calcium concentration in the nanomolar range using 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid. Anal Biochem (1991) 1.51
Acidification of endocytic compartments and the intracellular pathways of ligands and receptors. J Cell Biochem (1984) 1.49
Cytoskeleton-dependent membrane domain segregation during neutrophil polarization. Mol Biol Cell (2001) 1.47
Epigenetic heterogeneity at imprinted loci in normal populations. Biochem Biophys Res Commun (2001) 1.47
Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A (1986) 1.45
Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. J Biol Chem (1997) 1.45
Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells. J Cell Biol (1987) 1.42
Distribution and transport of cholesterol in Caenorhabditis elegans. Mol Biol Cell (2001) 1.42
Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. J Biol Chem (1999) 1.42
Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. Proc Natl Acad Sci U S A (1986) 1.40
Thyrotropin-releasing hormone-induced changes in intracellular [Ca2+] measured by microspectrofluorometry on individual quin2-loaded cells. J Cell Biol (1984) 1.39
Neutrophil polarity and locomotion are associated with surface redistribution of leukosialin (CD43), an antiadhesive membrane molecule. Blood (2000) 1.38
Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons. JAMA (1997) 1.38
Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules. J Cell Biol (1983) 1.37
Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits. Proc Natl Acad Sci U S A (1979) 1.36
Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. Am J Hum Genet (1993) 1.36
Cytosolic free calcium increases before and oscillates during frustrated phagocytosis in macrophages. J Cell Biol (1987) 1.35
IMPT1, an imprinted gene similar to polyspecific transporter and multi-drug resistance genes. Hum Mol Genet (1998) 1.35
Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors. Hum Mol Genet (1996) 1.31
Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City. Am J Hum Genet (1996) 1.30
Regulation of placental efficiency for nutrient transport by imprinted genes. Placenta (2006) 1.29
Attachment to fibronectin or vitronectin makes human neutrophil migration sensitive to alterations in cytosolic free calcium concentration. J Cell Biol (1991) 1.26
Association between the APOE genotype and psychopathologic symptoms in Alzheimer's disease. Neurology (2002) 1.25
Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts. Proc Natl Acad Sci U S A (1980) 1.25
Genetic influences on memory performance in familial Alzheimer disease. Neurology (2004) 1.23
Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages. J Cell Biol (1990) 1.22
Elevated plasma amyloid beta-peptide 1-42 and onset of dementia in adults with Down syndrome. Neurosci Lett (2001) 1.21