Receptor-mediated endocytosis of diphtheria toxin by cells in culture.

PubWeight™: 1.59‹?› | Rank: Top 4%

🔗 View Article (PMC 346318)

Published in Proc Natl Acad Sci U S A on May 01, 1982

Authors

J H Keen, F R Maxfield, M C Hardegree, W H Habig

Articles citing this

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol (1982) 5.11

Acute cholesterol depletion inhibits clathrin-coated pit budding. Proc Natl Acad Sci U S A (1999) 3.95

Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome. J Cell Biol (1989) 3.84

Bacterial toxins: cellular mechanisms of action. Microbiol Rev (1984) 3.42

Assembly polypeptides from coated vesicles mediate reassembly of unique clathrin coats. J Cell Biol (1983) 3.06

Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin. J Cell Biol (1985) 2.71

Membrane receptors for bacterial toxins. Microbiol Rev (1983) 2.41

Mutant Chinese hamster ovary cells pleiotropically defective in receptor-mediated endocytosis. J Cell Biol (1983) 2.17

Anthrax protective antigen interacts with a specific receptor on the surface of CHO-K1 cells. Infect Immun (1991) 2.12

Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line. J Cell Biol (1983) 1.96

Acidification of endocytic vesicles by an ATP-dependent proton pump. J Cell Biol (1983) 1.84

Receptor-mediated entry of diphtheria toxin into monkey kidney (Vero) cells: electron microscopic evaluation. Infect Immun (1985) 1.36

Binding and uptake of diphtheria toxin by toxin-resistant Chinese hamster ovary and mouse cells. Mol Cell Biol (1983) 1.29

Clostridium perfringens epsilon-toxin acts on MDCK cells by forming a large membrane complex. J Bacteriol (1997) 1.26

Pertussis toxin-mediated ADP-ribosylation of target proteins in Chinese hamster ovary cells involves a vesicle trafficking mechanism. Infect Immun (1995) 1.16

Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments. J Cell Biol (1984) 1.08

Identification of diphtheria toxin receptor and a nonproteinous diphtheria toxin-binding molecule in Vero cell membrane. J Cell Biol (1988) 0.98

Expression of functional diphtheria toxin receptors on highly toxin-sensitive mouse cells that specifically bind radioiodinated toxin. Proc Natl Acad Sci U S A (1992) 0.93

Diphtheria toxin does not enter resistant cells by receptor-mediated endocytosis. Infect Immun (1983) 0.90

Isolation of diphtheria toxin-sensitive mouse cells from a toxin-resistant population transfected with monkey DNA. Proc Natl Acad Sci U S A (1990) 0.90

Entry of diphtheria toxin into cells: possible existence of cellular factor(s) for entry of diphtheria toxin into cells was studied in somatic cell hybrids and hybrid toxins. J Cell Biol (1984) 0.78

Anti-idiotypic antibodies that protect cells against the action of diphtheria toxin. Proc Natl Acad Sci U S A (1989) 0.77

Articles cited by this

Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

Coated pits, coated vesicles, and receptor-mediated endocytosis. Nature (1979) 17.18

On the entry of Semliki forest virus into BHK-21 cells. J Cell Biol (1980) 11.05

Diphtheria toxin. Annu Rev Biochem (1977) 8.44

Diphtheria toxin: mode of action and structure. Bacteriol Rev (1975) 7.47

Diphtheria toxin entry into cells is facilitated by low pH. J Cell Biol (1980) 4.62

One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell (1978) 4.06

Collection of insulin, EGF and alpha2-macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization. Cell (1978) 3.90

The receptosome: an intermediate organelle of receptor mediated endocytosis in cultured fibroblasts. Cell (1980) 3.88

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement. J Cell Biol (1980) 3.64

Diphtheria toxin forms transmembrane channels in planar lipid bilayers. Proc Natl Acad Sci U S A (1981) 3.17

The visualization of fluorescent proteins in living cells by video intensification microscopy (VIM). Cell (1978) 2.89

Cell culture reactivity to diphtheria, Staphylococcus, tetanus and Escherichia coli toxins. J Immunol (1962) 2.65

alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. J Cell Biol (1979) 2.48

In vitro inhibition of diphtheria toxin action by ammonium salts and amines. J Bacteriol (1965) 2.38

Receptor-mediated internalization of Pseudomonas toxin by mouse fibroblasts. Cell (1980) 2.17

Association of diphtheria toxin with Vero cells. Demonstration of a receptor. J Biol Chem (1978) 2.13

Inhibition of diphtheria toxin degradation and cytotoxic action by chloroquine. J Biol Chem (1980) 2.06

Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells. J Biol Chem (1979) 1.94

Diphtheria toxin and related proteins. II. Kinetic studies on intoxication of HeLa cells by diphtheria toxin and related proteins. J Biol Chem (1973) 1.87

Interaction of diphtheria toxin with mammalian cell membranes. J Biol Chem (1976) 1.74

Studies on the mode of action of diphtheria toxin. II. Protein synthesis in primary heart cell cultures. J Exp Med (1967) 1.31

Genetic analysis of the cell surface: association of human chromosome 5 with sensitivity to diphtheria toxin in mouse-human somatic cell hybrids. Proc Natl Acad Sci U S A (1975) 1.26

Site in cell-free protein synthesis sensitive to diphtheria toxin. J Bacteriol (1968) 1.18

Protection of mammalian cells from diphtheria toxin by exogenous nucleotides. Can J Microbiol (1979) 1.12

Methylamine stimulates the action of ricin toxin but inhibits that of diphtheria toxin. J Biol Chem (1981) 1.10

Demonstration of diphtheria toxin receptors on surface membranes from both toxin-sensitive and toxin-resistant species. J Biol Chem (1978) 1.09

Receptor-mediated endocytosis of alpha 2-macroglobulin in cultured fibroblasts. J Histochem Cytochem (1980) 1.04

United States standard diphtheria toxin for the Schick text and the erythema potency assay for the Schick text dose. Infect Immun (1971) 0.96

Serum effects on the response of mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtheriae. Can J Microbiol (1977) 0.85

Articles by these authors

Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem (1974) 27.82

Endocytosis. Physiol Rev (1997) 7.33

Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell (1982) 7.23

Preparation and purification of glucanase and chitinase from bean leaves. Plant Physiol (1971) 7.08

Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell (1984) 6.50

Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature (1996) 6.32

Membrane transport in the endocytic pathway. Curr Opin Cell Biol (1995) 5.86

Assays for differentiation of glutathione S-transferases. Methods Enzymol (1981) 5.69

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells. J Biol Chem (1980) 5.24

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol (1982) 5.11

Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J Cell Biol (1993) 5.08

Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol (1984) 4.88

Clathrin-coated vesicles: isolation, dissociation and factor-dependent reassociation of clathrin baskets. Cell (1979) 4.81

Spatial control of coated-pit dynamics in living cells. Nat Cell Biol (1999) 4.57

Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science (1994) 4.36

Acute cholesterol depletion inhibits clathrin-coated pit budding. Proc Natl Acad Sci U S A (1999) 3.95

Collection of insulin, EGF and alpha2-macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization. Cell (1978) 3.90

Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome. J Cell Biol (1989) 3.84

Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor. J Cell Biol (1987) 3.28

Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature (1995) 3.22

Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells. Nat Cell Biol (2001) 3.22

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron (1996) 3.14

Assembly polypeptides from coated vesicles mediate reassembly of unique clathrin coats. J Cell Biol (1983) 3.06

Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J Cell Biol (1995) 3.03

Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy. J Cell Sci (1994) 2.88

Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature (1980) 2.82

The identity of glutathione S-transferase B with ligandin, a major binding protein of liver. Proc Natl Acad Sci U S A (1974) 2.77

Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol Biol Cell (1995) 2.74

Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO J (1998) 2.63

Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails. J Cell Biol (1999) 2.55

alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. J Cell Biol (1979) 2.48

Multiple forms of human glutathione S-transferase and their affinity for bilirubin. Eur J Biochem (1975) 2.46

An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. J Cell Biol (1998) 2.43

Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits. J Cell Biol (1999) 2.43

Cholesterol depletion induces large scale domain segregation in living cell membranes. Proc Natl Acad Sci U S A (2001) 2.41

Amines inhibit the clustering of alpha2-macroglobulin and EGF on the fibroblast cell surface. Nature (1979) 2.41

Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophys J (1998) 2.30

Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes. J Cell Biol (1992) 2.24

The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro. J Cell Biol (2001) 2.20

Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells. J Cell Biol (1995) 2.19

Ca2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. J Cell Sci (2000) 2.19

Status of empirical methods for the prediction of protein backbone topography. Biochemistry (1976) 2.12

Oriented endocytic recycling of alpha5beta1 in motile neutrophils. Blood (2000) 2.11

Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain. Cell Regul (1990) 2.09

The effect of neighboring charges on the helix forming ability of charged amino acids in proteins. Macromolecules (1976) 2.08

Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways. J Cell Biol (1999) 2.06

Immunization against neonatal tetanus in New Guinea. Antitoxin response of pregnant women to adjuvant and plain toxoids. Bull World Health Organ (1965) 2.05

Characterization of rapid membrane internalization and recycling. J Biol Chem (2000) 2.03

Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. J Cell Biol (1995) 2.02

Role of membrane organization and membrane domains in endocytic lipid trafficking. Traffic (2000) 2.02

Glutathione transferase from human erythrocytes. Nonidentity with the enzymes from liver. Arch Biochem Biophys (1978) 2.00

Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells. J Cell Biol (1989) 1.98

Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line. J Cell Biol (1983) 1.96

Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain. J Biol Chem (1997) 1.94

Binding of nonsubstrate ligands to the glutathione S-transferases. J Biol Chem (1975) 1.93

Structural and functional division into two domains of the large (100- to 115-kDa) chains of the clathrin-associated protein complex AP-2. Proc Natl Acad Sci U S A (1989) 1.91

Glutathione S-transferase A. A novel kinetic mechanism in which the major reaction pathway depends on substrate concentration. J Biol Chem (1974) 1.91

Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus. J Biol Chem (1997) 1.88

The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking. Mol Cell (2001) 1.87

Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding. EMBO J (1999) 1.86

Acidification of endocytic vesicles by an ATP-dependent proton pump. J Cell Biol (1983) 1.84

Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells. J Cell Biol (1987) 1.82

Significance of hypocalcaemia in neonatal convulsions. Arch Dis Child (1969) 1.77

Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila. Infect Immun (1998) 1.75

Mechanism for the several activities of the glutathione S-transferases. J Biol Chem (1976) 1.74

Sphingomyelinase treatment induces ATP-independent endocytosis. J Cell Biol (1998) 1.72

Outbreak of infantile gastro-enteritis caused by Escherichia coli O114. Arch Dis Child (1970) 1.71

Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix. J Leukoc Biol (1997) 1.69

Transient increases in cytosolic free calcium appear to be required for the migration of adherent human neutrophils. J Cell Biol (1990) 1.69

Local cytoplasmic calcium gradients in living mitotic cells. Nature (1985) 1.69

Modulation of the arrestin-clathrin interaction in cells. Characterization of beta-arrestin dominant-negative mutants. J Biol Chem (1997) 1.69

Intracellular fusion of sequentially formed endocytic compartments. J Cell Biol (1988) 1.67

Isolation of a temperature-sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment. J Cell Physiol (1993) 1.63

Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling. J Biol Chem (1997) 1.61

Inflicted burns and scalds in children. Br Med J (1975) 1.58

A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway. J Biol Chem (1996) 1.58

The phosphorylation of coated membrane proteins in intact neurons. J Cell Biol (1986) 1.57

Interaction of phosphoinositide cycle intermediates with the plasma membrane-associated clathrin assembly protein AP-2. J Biol Chem (1991) 1.54

The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected. J Cell Biol (1993) 1.54

Tetanus toxin interactions with thyroid plasma membranes. Implications for structure and function of tetanus toxin receptors and potential pathophysiological significance. J Biol Chem (1977) 1.53

Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science (1992) 1.53

Immunization against neonatal tetanus in New Guinea. 3. The toxin-neutralization test and the response of guinea-pigs to the toxoids as used in the immunization schedules in New Guinea. Bull World Health Organ (1970) 1.52

Preparation of solutions with free calcium concentration in the nanomolar range using 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid. Anal Biochem (1991) 1.51

The structural gene for tetanus neurotoxin is on a plasmid. Science (1984) 1.51

The Emory prospective randomized trial: selective versus nonselective shunt to control variceal bleeding. Ten year follow-up. Ann Surg (1985) 1.50

Glutathione S-transferases (rat and human). Methods Enzymol (1981) 1.50

Acidification of endocytic compartments and the intracellular pathways of ligands and receptors. J Cell Biochem (1984) 1.49

Cytoskeleton-dependent membrane domain segregation during neutrophil polarization. Mol Biol Cell (2001) 1.47

Glutathione S-transferase AA from rat liver. Arch Biochem Biophys (1976) 1.46

Mapping of the molecular determinants involved in the interaction between eps15 and AP-2. Cancer Res (1997) 1.46

Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A (1986) 1.45

Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. J Biol Chem (1997) 1.45

Distribution and transport of cholesterol in Caenorhabditis elegans. Mol Biol Cell (2001) 1.42

Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. J Biol Chem (1999) 1.42

Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells. J Cell Biol (1987) 1.42

Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. Proc Natl Acad Sci U S A (1986) 1.40

Thyrotropin-releasing hormone-induced changes in intracellular [Ca2+] measured by microspectrofluorometry on individual quin2-loaded cells. J Cell Biol (1984) 1.39