Published in J Clin Invest on June 01, 1984
Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies. J Clin Invest (1986) 2.05
Reduced interferon-gamma mRNA levels in human neonates. Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation. J Exp Med (1986) 1.75
Activation of neonatal and adult human macrophages by alpha, beta, and gamma interferons. Infect Immun (1985) 1.20
Neonatal innate immunity to infectious agents. Infect Immun (2006) 1.11
Nonoxidative microbicidal activity in normal human alveolar and peritoneal macrophages. Infect Immun (1987) 1.01
Production of interleukin-1 by mononuclear cells of newborns and their mothers. Clin Exp Immunol (1987) 0.84
Presence of gamma interferon in human acute and congenital toxoplasmosis. J Clin Microbiol (1990) 0.80
IL-1 beta and IL-3-like activity in preterm infants. Clin Exp Immunol (1993) 0.76
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J Exp Med (1983) 14.08
A simple technique for eliminating interference by detergents in the Lowry method of protein determination. Anal Biochem (1975) 6.36
Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine. J Clin Invest (1983) 5.88
Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens. J Exp Med (1980) 5.23
Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell. J Exp Med (1977) 4.59
Interleukin 2-mediated immune interferon (IFN-gamma) production by human T cells and T cell subsets. J Immunol (1983) 4.25
Macrophages and age-dependent resistance to Herpes simplex virus in mice. J Immunol (1970) 4.15
Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates. J Exp Med (1979) 3.72
Macrophage oxygen-dependent antimicrobial activity. III. Enhanced oxidative metabolism as an expression of macrophage activation. J Exp Med (1980) 3.43
Inhibition of multiplication of Toxoplasma gondii by human monocytes exposed to T-lymphocyte products. J Exp Med (1975) 3.17
Killing of intracellular Leishmania donovani by human mononuclear phagocytes. Evidence for oxygen-dependent and -independent leishmanicidal activity. J Clin Invest (1983) 3.06
Induction of resistance to Toxoplasma gondii in human macrophages by soluble lymphocyte products. J Immunol (1976) 2.79
Characterization of the effects of endotoxin on macrophage tumor cell killing. J Immunol (1978) 2.65
Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon. J Immunol (1983) 2.61
Lymphokines enhance the capacity of human monocytes to secret reactive oxygen intermediates. J Clin Invest (1982) 2.23
Inhibition of the growth of Rickettsia prowazekii in cultured fibroblasts by lymphokines. J Exp Med (1983) 2.20
Cultured human monocytes require exposure to bacterial products to maintain an optimal oxygen radical response. J Immunol (1982) 2.19
Macrophages in resistance to rickettsial infections: characterization of lymphokines that induce rickettsiacidal activity in macrophages. J Immunol (1981) 1.94
Lymphokine enhances oxygen-independent activity against intracellular pathogens. J Exp Med (1983) 1.93
A method to evaluate the capacity of monocytes and macrophages to inhibit multiplication of an intracellular pathogen. J Immunol Methods (1979) 1.87
Deficiency of immune interferon production by leukocytes of normal newborns. Cell Immunol (1980) 1.85
Role for endogenous and acquired peroxidase in the toxoplasmacidal activity of murine and human mononuclear phagocytes. J Clin Invest (1982) 1.64
Activity of human blood leukocytes against Toxoplasma gondii. J Infect Dis (1979) 1.63
Mediation of immunity to intracellular infection (Toxoplasma and Besnoitia) within somatic cells. Infect Immun (1978) 1.52
Macrophage oxygen-dependent antimicrobial activity. IV. Role of endogenous scavengers of oxygen intermediates. J Exp Med (1980) 1.44
Growth of herpes simplex and cytomegalovirus in cultured human alveolar macrophages. Am Rev Respir Dis (1979) 1.32
Spontaneous activation of latent cytomegalovirus from murine spleen explants. Role of lymphocytes and macrophages in release and replication of virus. J Clin Invest (1982) 1.30
Macrophage activation for tumor cytotoxicity: induction of macrophage tumoricidal activity by lymphokines from EL-4, a continuous T cell line. J Immunol (1982) 1.27
Antibody to staphylococcal enterotoxin A-induced human immune interferon (IFN gamma). J Immunol (1981) 1.23
Toxicity and efficacy of human leukocyte interferon for treatment of cytomegalovirus pneumonia after marrow transplantation. J Infect Dis (1980) 1.22
Effects of monocytes from human neonates on lymphocyte transformation. Clin Exp Immunol (1979) 1.19
Interferon induction of natural killer cytotoxicity in human neonates. J Pediatr (1981) 1.09
Aging and the immune response. II. Lymphocyte responsiveness and macrophage activation in Toxoplasma gondii-infected mice. J Immunol (1978) 1.09
Isolation, purification and characteristics of mononuclear phagocytes from human placentas. J Immunol Methods (1983) 1.05
Immune competence of newborn lymphocytes. Pediatrics (1980) 1.05
Similarities of murine gamma interferon and the lymphokine that renders macrophages cytotoxic. J Interferon Res (1982) 1.05
Chemotactic and bactericidal capacities of human newborn monocytes. J Immunol (1976) 1.03
Cellular (T cell) immunity in the human newborn. Pediatrics (1979) 1.01
Lymphotoxin production and blast cell transformation by cord blood lymphocytes: dissociated lymphocyte function in newborn infants. Cell Immunol (1974) 1.01
Studies of the cell lineage of the effector cells that spontaneously lyse HSV-1 infected fibroblasts (NK(HSV-1)). J Immunol (1982) 1.00
Toxoplasma gondii: human interferon studies by plaque assay. Proc Soc Exp Biol Med (1979) 0.99
Monocyte function in human neonates. Infect Immun (1978) 0.99
Requirement for OKT8+ suppressor cell proliferation for suppression by human newborn T cells. Clin Exp Immunol (1981) 0.95
Leucocyte migration inhibition factor (LIF) production by lymphocytes of normal children, newborns, and children with immune deficiency. Clin Exp Immunol (1976) 0.92
Some physicochemical characteristics of an immune lymphocyte product which inhibits the multiplication of toxoplasma within mouse macrophages. Microbiol Immunol (1979) 0.91
Human macrophage migration inhibition factor: evidence for subunit structure. Science (1979) 0.91
Production of leukocytic pyrogen from phagocytes of neonates. J Infect Dis (1981) 0.90
How protozoa evade intracellular killing. Ann Intern Med (1983) 0.87
Characterization of the suppressor cell activity in human cord blood lymphocytes. J Clin Invest (1981) 0.81
Leukocyte function in healthy neonates following vaginal and cesarean section deliveries. J Pediatr (1982) 0.80
Production of migration inhibitory factor and blast cell transformation by cord blood lymphocytes. Int Arch Allergy Appl Immunol (1976) 0.77
Effects of muramyl dipeptide on superoxide anion release and on anti-microbial activity of human macrophages. Clin Exp Immunol (1982) 0.76
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J Exp Med (1978) 11.99
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci U S A (2000) 9.67
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity (2001) 9.45
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature (1999) 8.50
The Raji cell radioimmune assay for detecting immune complexes in human sera. J Clin Invest (1976) 8.06
An assembly domain of the Rous sarcoma virus Gag protein required late in budding. J Virol (1994) 5.87
Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens. J Exp Med (1980) 5.23
Positionally independent and exchangeable late budding functions of the Rous sarcoma virus and human immunodeficiency virus Gag proteins. J Virol (1995) 4.92
Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. N Engl J Med (1980) 4.90
Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg (1978) 4.55
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat Immunol (2001) 3.89
Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70. J Exp Med (1976) 3.51
Development of adverse sequelae in children born with subclinical congenital Toxoplasma infection. Pediatrics (1980) 3.21
Anti-glomerular basement membrane antibody-induced glomerulonephritis. Kidney Int (1973) 3.09
Immunosuppression and plasma-exchange in the treatment of Goodpasture's syndrome. Lancet (1976) 3.00
Diagnosis and management of pituitary abscess: a review of twenty-four cases. J Neurosurg (2001) 3.00
Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin. J Immunol (2001) 2.86
DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. J Neurosci (2001) 2.75
Ultrastructure of malignant rhabdoid tumor of the kidney. A distinctive renal tumor of children. Hum Pathol (1981) 2.64
Mechanism and modification of rejection of heterografts between divergent species. Transplant Proc (1970) 2.63
Binding of soluble immune complexes to human lymphoblastoid cells. II. Use of Raji cells to detect circulating immune complexes in animal and human sera. J Exp Med (1974) 2.51
Regulation of tumor necrosis factor/cachectin and IL-1 secretion in human mononuclear phagocytes. J Immunol (1988) 2.47
Abrogation of macrophage-dependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum. J Clin Invest (1981) 2.41
Necessity of the spacer peptide between CA and NC in the Rous sarcoma virus gag protein. J Virol (1993) 2.40
Criteria for evaluating patients undergoing chemotherapy for malignant brain tumors. J Neurosurg (1977) 2.39
Humoral antibodies and coagulation mechanisms in the accelerated or hyperacute rejection of renal homografts in sensitized canine recipients. Surgery (1970) 2.38
Clotting changes, including disseminated intravascular coagulation, during rapid renal-homograft rejection. N Engl J Med (1970) 2.33
Early pulmonary infection, inflammation, and clinical outcomes in infants with cystic fibrosis. Pediatr Pulmonol (2001) 2.24
Endovascular and surgical treatment of unruptured cerebral aneurysms: comparison of risks. Ann Neurol (2000) 2.20
Antitubular basement-membrane antibodies in methicillin-associated interstitial nephritis. N Engl J Med (1974) 2.20
Successful readministration of adeno-associated virus vectors to the mouse lung requires transient immunosuppression during the initial exposure. J Virol (1998) 2.11
Ceftizoxime versus vancomycin and gentamicin in neurosurgical prophylaxis: a randomized, prospective, blinded clinical study. Neurosurgery (1993) 2.10
Diagnosis of immunopathologic renal disease. Kidney Int (1974) 2.07
Meningiomas induced by high-dose cranial irradiation. J Neurosurg (1993) 2.05
Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies. J Clin Invest (1986) 2.05
In vivo clonogenic tumor cell kinetics following 1,3-bis(2-chloroethyl)-1-nitrosourea brain tumor therapy. Cancer Res (1976) 2.04
Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration. Nat Genet (1995) 2.03
Characterization of Haemophilus influenzae type b fimbriae. Infect Immun (1984) 2.00
Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg (1994) 2.00
An evaluation of elution techniques in the study of immune complex glomerulonephritis. J Immunol (1977) 1.96
Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness. J Immunol (1970) 1.93
Normal perfusion pressure breakthrough theory. Clin Neurosurg (1978) 1.87
Epidermoid cysts of the posterior fossa. J Neurosurg (1985) 1.85
Surgical treatment of syringomyelia. Favorable results with syringoperitoneal shunting. J Neurosurg (1984) 1.84
Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung. J Infect Dis (1988) 1.82
Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma. Cancer Treat Rep (1983) 1.81
Regulation of pp56lck during T-cell activation: functional implications for the src-like protein tyrosine kinases. EMBO J (1987) 1.80
Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int (1987) 1.78
T cell expression cloning of a Mycobacterium tuberculosis gene encoding a protective antigen associated with the early control of infection. J Immunol (2000) 1.76
Reduced interferon-gamma mRNA levels in human neonates. Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation. J Exp Med (1986) 1.75
Quantitation of acute and chronic serum sickness in the rabbit. J Exp Med (1971) 1.74
The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone. J Neurosurg (1990) 1.72
Evidence for a second function of the MA sequence in the Rous sarcoma virus Gag protein. J Virol (1996) 1.70
Randomized comparison of cisplatin/vincristine/fluorouracil and cisplatin/continuous infusion doxorubicin for treatment of pediatric hepatoblastoma: A report from the Children's Cancer Group and the Pediatric Oncology Group. J Clin Oncol (2000) 1.70
Current multimodality management of infectious intracranial aneurysms. Neurosurgery (2001) 1.68
Restricted production of interleukin 4 by activated human T cells. Proc Natl Acad Sci U S A (1988) 1.67
Glomerular sialic acid and proteinuria in human renal disease. Lab Invest (1973) 1.67
Survival and functional status after resection of recurrent glioblastoma multiforme. Neurosurgery (1998) 1.66
Detection of circulating immune complexes in patients with glomerulonephritis. Kidney Int (1977) 1.66
Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody. J Clin Invest (1995) 1.65
Cellular and molecular mechanisms for reduced interleukin 4 and interferon-gamma production by neonatal T cells. J Clin Invest (1991) 1.64
Role for endogenous and acquired peroxidase in the toxoplasmacidal activity of murine and human mononuclear phagocytes. J Clin Invest (1982) 1.64
Activity of human blood leukocytes against Toxoplasma gondii. J Infect Dis (1979) 1.63
Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide. J Clin Invest (1995) 1.62
Susceptibility of Legionella pneumophila to oxygen-dependent microbicidal systems. J Immunol (1982) 1.61
Neuroepithelial cysts of the posterior fossa. Case report. J Neurosurg (1990) 1.60
Evaluation of bromodeoxyuridine in glioblastoma multiforme: a Northern California Cancer Center Phase II study. Int J Radiat Oncol Biol Phys (1991) 1.59
Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression. Arch Biochem Biophys (1993) 1.59
Slow-flow vascular malformations of the pons: capillary telangiectasias? AJNR Am J Neuroradiol (1996) 1.58
Intracellular penetration and antimicrobial activity of antibiotics. J Antimicrob Chemother (1983) 1.58
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. Int J Radiat Oncol Biol Phys (1990) 1.57
Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells. J Exp Med (1993) 1.57
Development of acquired arteriovenous fistulas in rats due to venous hypertension. J Neurosurg (1994) 1.56
Immunologic basis for increased susceptibility of the neonate to infection. J Pediatr (1986) 1.55
Interstitial nephritis in rats immunized with heterologous tubular basement membrane. Kidney Int (1974) 1.54
Altered cardiac histology following apical right ventricular pacing in patients with congenital atrioventricular block. Pacing Clin Electrophysiol (1999) 1.53
Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene. J Immunol (1994) 1.52
Development of an animal brain tumor model and its response to therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Res (1973) 1.51
Complement dependence of antibody-induced mesangial cell injury in the rat. J Immunol (1987) 1.50
Experimental glomerulonephritis induced by in situ formation of immune complexes in glomerular capillary wall. Kidney Int (1979) 1.50
Application of the solid phase C1q and Raji cell radioimmune assays for the detection of circulating immune complexes in glomerulonephritis. J Clin Invest (1978) 1.50
Reoperation for recurrent glioblastoma and anaplastic astrocytoma. Neurosurgery (1987) 1.49
Primary central nervous system tumors: advances in knowledge and treatment. CA Cancer J Clin (1998) 1.49
Interstitial immune complex thyroiditis in mice: the role of autoantibody to thyroglobulin. J Exp Med (1974) 1.49
Goodpasture's syndrome associated with influenza A2 virus infection. Ann Intern Med (1972) 1.49
Photodynamic therapy of malignant tumours. Lancet (1972) 1.48
Cushing's disease. Selective trans-sphenoidal resection of pituitary microadenomas. N Engl J Med (1978) 1.48
Transsphenoidal microsurgery for growth hormone-secreting pituitary adenomas: initial outcome and long-term results. J Clin Endocrinol Metab (1998) 1.48
Pineal region tumors in children. J Neurosurg (1988) 1.47
The proximal regulatory element of the interferon-gamma promoter mediates selective expression in T cells. J Biol Chem (1996) 1.46
Endovascular treatment of vertebral artery dissections and pseudoaneurysms. J Neurosurg (1993) 1.46
Comparative susceptibility of group B streptococci and Staphylococcus aureus to killing by oxygen metabolites. J Infect Dis (1985) 1.45
Glomerular antigens in Heymann's nephritis: reactivity of eluted and circulating antibody. J Immunol (1982) 1.45
Glomerular complement components in human glomerulonephritis. J Clin Invest (1974) 1.43
Cerebrospinal fluid rhinorrhea in patients with untreated pituitary adenoma: report of two cases. Surg Neurol (1990) 1.42
Delayed infection after elective spinal instrumentation and fusion. A retrospective analysis of eight cases. Spine (Phila Pa 1976) (1997) 1.42
Role of the type 1 TNF receptor in lung inflammation after inhalation of endotoxin or Pseudomonas aeruginosa. Am J Physiol (1999) 1.42
Isolation and immunological characterization of human glomerular basement membrane antigens. Kidney Int (1973) 1.42
Structure and expression of lck transcripts in human lymphoid cells. J Cell Biochem (1988) 1.42
Direct laryngoscopy with the aid of a fiberoptic bronchoscope for tracheal intubation. Anesth Analg (1996) 1.39