Published in J Exp Med on December 01, 1974
Experimental glomerulonephritis in the isolated perfused rat kidney. J Clin Invest (1978) 4.45
Quantitative studies of in situ immune complex glomerulonephritis in the rat induced by planted, cationized antigen. J Exp Med (1982) 2.00
Rheumatoid factor-producing cells detected by direct hemolytic plaque assay. J Clin Invest (1976) 1.62
Application of the solid phase C1q and Raji cell radioimmune assays for the detection of circulating immune complexes in glomerulonephritis. J Clin Invest (1978) 1.50
Inhibition of specific cell-mediated cytotoxicity by monoclonal antibodies to human T cell antigens. Proc Natl Acad Sci U S A (1981) 1.41
Circulating immune complexes in various thyroid diseases. Clin Exp Immunol (1979) 1.10
Study of circulating immune complex size in systemic lupus erythematosus. Clin Exp Immunol (1981) 1.08
In situ formation of antigen-antibody complexes in the mouse glomerulus. Immunology (1979) 1.01
Studies on the pathogenesis of experimental autoimmune renal tubulointerstitial disease in guinea-pigs. III. The role of adjuvants in the induction of disease. Clin Exp Immunol (1976) 0.94
In vivo interaction of antibodies with cell surface antigens. A mechanism responsible for in situ formation of immune deposits in the zona pellucida of rabbit oocytes. J Clin Invest (1985) 0.90
In vitro expression of immunoglobulin M and G subclasses by murine B lymphocytes in response to a polyclonal activator from Actinomyces. Infect Immun (1980) 0.84
Cell surface phenotypes of radiolabeled immune long-lived lymphocytes that selectively localize in syngeneic tumours. Am J Pathol (1982) 0.83
The nature of the autoantibody response to thyroglobulin in murine strains with high or low susceptibility to the experimental induction of autoimmune thyroiditis. Clin Exp Immunol (1982) 0.83
Renal tubular immune complex formation in mice immunized with Tamm-Horsfall protein. Am J Pathol (1986) 0.82
Biochemical and immunological investigations on hypothyroidism in dogs. Can J Comp Med (1980) 0.81
Influence of methimazole on murine thyroiditis. Evidence for immunosuppression in vivo. J Clin Invest (1984) 0.79
Current trends in antifertility vaccine research. West J Med (1985) 0.76
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Humoral and cell-mediated immunity in experimental progressive thyroiditis in rabbits. Clin Exp Immunol (1975) 0.75
A method of trace iodination of proteins for immunologic studies. Int Arch Allergy Appl Immunol (1966) 43.66
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Pathologic mechanisms in neutrophil-mediated injury. Am J Pathol (1972) 2.57
Recent observations and concepts in immunological unresponsiveness and autoimmunity. Clin Exp Immunol (1971) 2.45
Transfer of experimental autoimmune thyroiditis by serum from thyroidectomized donors. J Exp Med (1969) 2.12
Diagnosis of immunopathologic renal disease. Kidney Int (1974) 2.07
Experimental allergic glomerulonephritis induced in the rabbit with homologous renal antigens. J Exp Med (1967) 1.76
Cellular events during induction of immunologic unresponsiveness in adult mice. J Immunol (1971) 1.72
Transfer of experimental autoimmune thyroiditis of the mouse by serum. J Immunol (1971) 1.71
Leukotactic factors in health and disease. Am J Pathol (1971) 1.71
Cellular events during the induction of experimental thyroiditis in the rabbit. J Exp Med (1972) 1.66
Interstitial nephritis in rats immunized with heterologous tubular basement membrane. Kidney Int (1974) 1.54
Roles of T and B lymphocytes in the termination of unresponsiveness to autologous thyroglobulin in mice. J Exp Med (1974) 1.38
Immunoglobulins (E,M,G) and complement in the connective tissues of the thyroid in Graves's disease. N Engl J Med (1972) 1.31
The behavior of autologous thyroglobulin in the circulation of rabbits immunized with either heterologous or altered homologous thyroglobulin. J Immunol (1967) 1.13
The biological effects of anti-thyroid antibodies. Thyroid eosinophilia following passive transfer of anti-thyroglobulin antibody. Immunology (1967) 1.09
Allergic encephalomyelitis: effect of complement depletion with cobra venom. Proc Soc Exp Biol Med (1971) 1.02
Perpetuation of autoimmune thyroiditis and production of secondary renal lesions following periodic injections of aqueous preparations of altered thyroglobulin. Clin Exp Immunol (1969) 0.97
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Ultrastructural alterations of the follicular basement membrane in Hashimoto's thyroiditis. Report of eight cases with basement deposits. Am J Med (1973) 0.92
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Induction of thyroiditis in guinea-pigs by intravenous injection of rabbit anti-guinea-pig thyroglobulin serum. I. Light microscopic study. Immunology (1969) 0.87
Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J Exp Med (1978) 11.99
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci U S A (2000) 9.67
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity (2001) 9.45
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature (1999) 8.50
The Raji cell radioimmune assay for detecting immune complexes in human sera. J Clin Invest (1976) 8.06
An assembly domain of the Rous sarcoma virus Gag protein required late in budding. J Virol (1994) 5.87
Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens. J Exp Med (1980) 5.23
Positionally independent and exchangeable late budding functions of the Rous sarcoma virus and human immunodeficiency virus Gag proteins. J Virol (1995) 4.92
Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery. N Engl J Med (1980) 4.90
Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg (1978) 4.55
Kinetic differences in unresponsiveness of thymus and bone marrow cells. Science (1971) 4.13
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat Immunol (2001) 3.89
Endogenous oncornaviral gene expression in adult and fetal mice: quantitative, histologic, and physiologic studies of the major viral glycorprotein, gp70. J Exp Med (1976) 3.51
Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils. J Clin Invest (1975) 3.39
Development of adverse sequelae in children born with subclinical congenital Toxoplasma infection. Pediatrics (1980) 3.21
Immunologic properties of bacterial lipopolysaccharide (LPS): correlation between the mitogenic, adjuvant, and immunogenic activities. J Immunol (1975) 3.18
Anti-glomerular basement membrane antibody-induced glomerulonephritis. Kidney Int (1973) 3.09
Cellular sites of immunologic unresponsiveness. Proc Natl Acad Sci U S A (1970) 3.01
Immunosuppression and plasma-exchange in the treatment of Goodpasture's syndrome. Lancet (1976) 3.00
Diagnosis and management of pituitary abscess: a review of twenty-four cases. J Neurosurg (2001) 3.00
Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin. J Immunol (2001) 2.86
Immunological unresponsiveness. Adv Immunol (1973) 2.75
DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. J Neurosci (2001) 2.75
Mechanism and modification of rejection of heterografts between divergent species. Transplant Proc (1970) 2.63
Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. Proc Natl Acad Sci U S A (1973) 2.61
Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol (1993) 2.56
Binding of soluble immune complexes to human lymphoblastoid cells. II. Use of Raji cells to detect circulating immune complexes in animal and human sera. J Exp Med (1974) 2.51
Regulation of tumor necrosis factor/cachectin and IL-1 secretion in human mononuclear phagocytes. J Immunol (1988) 2.47
Recent observations and concepts in immunological unresponsiveness and autoimmunity. Clin Exp Immunol (1971) 2.45
Abrogation of macrophage-dependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum. J Clin Invest (1981) 2.41
Necessity of the spacer peptide between CA and NC in the Rous sarcoma virus gag protein. J Virol (1993) 2.40
Criteria for evaluating patients undergoing chemotherapy for malignant brain tumors. J Neurosurg (1977) 2.39
Humoral antibodies and coagulation mechanisms in the accelerated or hyperacute rejection of renal homografts in sensitized canine recipients. Surgery (1970) 2.38
Clotting changes, including disseminated intravascular coagulation, during rapid renal-homograft rejection. N Engl J Med (1970) 2.33
Analysis of autoimmunity through experimental models of thyroiditis and allergic encephalomyelitis. Adv Immunol (1980) 2.27
Early pulmonary infection, inflammation, and clinical outcomes in infants with cystic fibrosis. Pediatr Pulmonol (2001) 2.24
Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. J Exp Med (1975) 2.22
Antitubular basement-membrane antibodies in methicillin-associated interstitial nephritis. N Engl J Med (1974) 2.20
Endovascular and surgical treatment of unruptured cerebral aneurysms: comparison of risks. Ann Neurol (2000) 2.20
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
Transfer of experimental autoimmune thyroiditis by serum from thyroidectomized donors. J Exp Med (1969) 2.12
Successful readministration of adeno-associated virus vectors to the mouse lung requires transient immunosuppression during the initial exposure. J Virol (1998) 2.11
Ceftizoxime versus vancomycin and gentamicin in neurosurgical prophylaxis: a randomized, prospective, blinded clinical study. Neurosurgery (1993) 2.10
Diagnosis of immunopathologic renal disease. Kidney Int (1974) 2.07
Meningiomas induced by high-dose cranial irradiation. J Neurosurg (1993) 2.05
Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies. J Clin Invest (1986) 2.05
In vivo clonogenic tumor cell kinetics following 1,3-bis(2-chloroethyl)-1-nitrosourea brain tumor therapy. Cancer Res (1976) 2.04
Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration. Nat Genet (1995) 2.03
Postoperative irradiation for subtotally resected meningiomas. A retrospective analysis of 140 patients treated from 1967 to 1990. J Neurosurg (1994) 2.00
The production of thyroiditis and antibody following injection of unaltered thyroglobulin without adjuvant into rabbits previously stimulated with altered thyroglobulin. J Exp Med (1965) 1.96
An evaluation of elution techniques in the study of immune complex glomerulonephritis. J Immunol (1977) 1.96
Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness. J Immunol (1970) 1.93
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J Immunol (1993) 1.88
Normal perfusion pressure breakthrough theory. Clin Neurosurg (1978) 1.87
Epidermoid cysts of the posterior fossa. J Neurosurg (1985) 1.85
Surgical treatment of syringomyelia. Favorable results with syringoperitoneal shunting. J Neurosurg (1984) 1.84
The production of antisera to human gammaGlobulin subclasses in rabbits using immunological unresponsiveness. J Immunol (1968) 1.82
Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung. J Infect Dis (1988) 1.82
Comparisons of carmustine, procarbazine, and high-dose methylprednisolone as additions to surgery and radiotherapy for the treatment of malignant glioma. Cancer Treat Rep (1983) 1.81
Studies on the induction of immunologic unresponsiveness. 3. Antigen form and mouse strain variation. J Immunol (1969) 1.81
Regulation of pp56lck during T-cell activation: functional implications for the src-like protein tyrosine kinases. EMBO J (1987) 1.80
Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J Immunol (1990) 1.79
Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int (1987) 1.78
T cell expression cloning of a Mycobacterium tuberculosis gene encoding a protective antigen associated with the early control of infection. J Immunol (2000) 1.76
Reduced interferon-gamma mRNA levels in human neonates. Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation. J Exp Med (1986) 1.75
Quantitation of acute and chronic serum sickness in the rabbit. J Exp Med (1971) 1.74
Cellular events during induction of immunologic unresponsiveness in adult mice. J Immunol (1971) 1.72
The treatment of medulloblastoma. Results of a prospective randomized trial of radiation therapy with and without CCNU, vincristine, and prednisone. J Neurosurg (1990) 1.72
Evidence for a second function of the MA sequence in the Rous sarcoma virus Gag protein. J Virol (1996) 1.70
Studies on the induction of immunologic unresponsiveness. II. Kinetics. J Immunol (1967) 1.70
Cellular events in the induction of experimental allergic encephalomyelitis in rats. J Exp Med (1976) 1.69
Current multimodality management of infectious intracranial aneurysms. Neurosurgery (2001) 1.68
Restricted production of interleukin 4 by activated human T cells. Proc Natl Acad Sci U S A (1988) 1.67
Survival and functional status after resection of recurrent glioblastoma multiforme. Neurosurgery (1998) 1.66
Detection of circulating immune complexes in patients with glomerulonephritis. Kidney Int (1977) 1.66
Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody. J Clin Invest (1995) 1.65
Cellular and molecular mechanisms for reduced interleukin 4 and interferon-gamma production by neonatal T cells. J Clin Invest (1991) 1.64
Role for endogenous and acquired peroxidase in the toxoplasmacidal activity of murine and human mononuclear phagocytes. J Clin Invest (1982) 1.64
Activity of human blood leukocytes against Toxoplasma gondii. J Infect Dis (1979) 1.63
Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide. J Clin Invest (1995) 1.62
Susceptibility of Legionella pneumophila to oxygen-dependent microbicidal systems. J Immunol (1982) 1.61
Neuroepithelial cysts of the posterior fossa. Case report. J Neurosurg (1990) 1.60
The cellular and subcellular bases of immunosenescence. Adv Immunol (1989) 1.59
Evaluation of bromodeoxyuridine in glioblastoma multiforme: a Northern California Cancer Center Phase II study. Int J Radiat Oncol Biol Phys (1991) 1.59
Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression. Arch Biochem Biophys (1993) 1.59
Slow-flow vascular malformations of the pons: capillary telangiectasias? AJNR Am J Neuroradiol (1996) 1.58
Intracellular penetration and antimicrobial activity of antibiotics. J Antimicrob Chemother (1983) 1.58
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. Int J Radiat Oncol Biol Phys (1990) 1.57
Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells. J Exp Med (1993) 1.57
Development of acquired arteriovenous fistulas in rats due to venous hypertension. J Neurosurg (1994) 1.56
Immunologic basis for increased susceptibility of the neonate to infection. J Pediatr (1986) 1.55
Interstitial nephritis in rats immunized with heterologous tubular basement membrane. Kidney Int (1974) 1.54
Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene. J Immunol (1994) 1.52
B-lymphocytes activation by the Fc region of IgG. J Exp Med (1977) 1.51
Development of an animal brain tumor model and its response to therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Res (1973) 1.51
Complement dependence of antibody-induced mesangial cell injury in the rat. J Immunol (1987) 1.50
Experimental glomerulonephritis induced by in situ formation of immune complexes in glomerular capillary wall. Kidney Int (1979) 1.50
Application of the solid phase C1q and Raji cell radioimmune assays for the detection of circulating immune complexes in glomerulonephritis. J Clin Invest (1978) 1.50