Published in Nature on March 10, 1983
Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci U S A (1984) 3.13
Developmental and tissue-specific expression of a family of transcripts related to rat insulin-like growth factor II mRNA. Nucleic Acids Res (1985) 1.84
Differential expression of insulin-like growth factor genes in rat central nervous system. Proc Natl Acad Sci U S A (1988) 1.47
Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level. Proc Natl Acad Sci U S A (1987) 1.47
Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C. Proc Natl Acad Sci U S A (1984) 1.30
Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring. BMC Genomics (2009) 1.29
Insulin-like growth factor II (IGF II) in human brain: regional distribution of IGF II and of higher molecular mass forms. Proc Natl Acad Sci U S A (1985) 1.16
Tissue-specific expression of insulin-like growth factor II mRNAs with distinct 5' untranslated regions. Proc Natl Acad Sci U S A (1987) 1.05
Ontogenesis of prolactin receptors in the human fetus in early gestation. Implications for tissue differentiation and development. J Clin Invest (1997) 1.01
Human fetal and adult chondrocytes. Effect of insulinlike growth factors I and II, insulin, and growth hormone on clonal growth. J Clin Invest (1986) 0.98
Disproportionate growth in mice with Igf-2 transgenes. Proc Natl Acad Sci U S A (1994) 0.96
Comparative binding of bovine, human and rat insulin-like growth factors to membrane receptors and to antibodies against human insulin-like growth factor-1. Biochem J (1986) 0.92
Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta. Proc Natl Acad Sci U S A (1988) 0.91
Activation of an imprinted Igf 2 gene in mouse somatic cell cultures. Mol Cell Biol (1993) 0.91
Biological markers during early pregnancy: trophoblastic signals of the peri-implantation period. Environ Health Perspect (1987) 0.91
Expression of insulin-like growth factor II in human placentas from normal and diabetic pregnancies. Proc Natl Acad Sci U S A (1986) 0.87
Placental lactogen administration reverses the effect of low-protein diet on maternal and fetal serum somatomedin levels in the pregnant rat. Proc Natl Acad Sci U S A (1984) 0.86
Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth. PLoS One (2013) 0.85
Demonstration of the production and physiological role of insulin-like growth factor II in rat thyroid follicular cells in culture. J Clin Invest (1988) 0.82
Preferential association of the insulin-like growth factors I and II with metabolically inactive and active carrier-bound complexes in serum. Biochem J (1987) 0.80
Insulin-related genes expressed in human placenta from normal and diabetic pregnancies. Proc Natl Acad Sci U S A (1985) 0.79
Regulation of insulin-like growth factor II receptors by growth hormone and insulin in rat adipocytes. Proc Natl Acad Sci U S A (1987) 0.77
Purification of a distinct placental lactogen receptor, a new member of the growth hormone/prolactin receptor family. J Clin Invest (1989) 0.76
Histopathology and prognostic factors in bronchial carcinoid tumours. Thorax (1994) 0.75
Exploration of the pulmonary circulation. Festschrift to Professor Donald Heath. Thorax (1994) 0.75
Penicillin-binding proteins of penicillin-susceptible and -resistant pneumococci: immunological relatedness of altered proteins and changes in peptides carrying the beta-lactam binding site. Antimicrob Agents Chemother (1986) 2.72
Antibiotic tolerance among clinical isolates of bacteria. Rev Infect Dis (1985) 2.32
The nature and regulation of the receptors for insulin-like growth factors. Annu Rev Physiol (1985) 2.19
Direct demonstration of separate receptors for growth and metabolic activities of insulin and multiplication-stimulating activity (an insulinlike growth factor) using antibodies to the insulin receptor. J Clin Invest (1980) 2.15
NIH conference. Insulin-like growth factors in health and disease. Ann Intern Med (1992) 1.95
Demonstration of two subtypes of insulin-like growth factor receptors by affinity cross-linking. J Biol Chem (1981) 1.90
Glucose intolerance in cystic fibrosis. N Engl J Med (1969) 1.85
Leuconostoc, an emerging vancomycin-resistant pathogen. Lancet (1987) 1.80
Alterations in kinetic properties of penicillin-binding proteins of penicillin-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother (1986) 1.76
Alterations in penicillin-binding proteins of clinical and laboratory isolates of pathogenic Streptococcus pneumoniae with low levels of penicillin resistance. J Infect Dis (1986) 1.71
Tuberculosis and the acquired immunodeficiency syndrome at a New York City hospital: 1978-1985. Chest (1987) 1.67
Characterization of the binding of multiplication-stimulating activity to a receptor for growth polypeptides in chick embryo fibroblasts. J Biol Chem (1977) 1.63
Oxygen tension directs the differentiation pathway of human cytotrophoblast cells. Placenta (2007) 1.63
Increased levels of multiplication-stimulating activity, an insulin-like growth factor, in fetal rat serum. Proc Natl Acad Sci U S A (1980) 1.62
Inducible and constitutive expression of vanC-1-encoded resistance to vancomycin in Enterococcus gallinarum. Antimicrob Agents Chemother (1995) 1.61
Isolation of a cDNA clone encoding rat insulin-like growth factor-II precursor. Nature (1984) 1.58
Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants. Arch Biochem Biophys (1988) 1.55
DNA synthesis in human fibroblasts: stimulation by insulin and by nonsuppressible insulin-like activity (NSILA-S). J Clin Endocrinol Metab (1974) 1.53
Interactions of insulin-like growth factors I and II and multiplication-stimulating activity with receptors and serum carrier proteins. Endocrinology (1980) 1.48
Mobilization of vancomycin resistance by transposon-mediated fusion of a VanA plasmid with an Enterococcus faecium sex pheromone-response plasmid. Gene (1996) 1.47
Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. J Neurosci (1986) 1.47
MSA and EGF receptors on sarcoma virus transformed cells and human fibrosarcoma cells in culture. Nature (1977) 1.45
Developmental regulation of insulin-like growth factor II mRNA in different rat tissues. J Biol Chem (1986) 1.44
Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. J Clin Invest (1989) 1.41
Purification and characterization of multiplication-stimulating activity. Insulin-like growth factors purified from rat-liver-cell-conditioned medium. Eur J Biochem (1980) 1.39
Further characterization of growth hormone-dependent somatomedin-binding proteins in rat serum and demonstration of somatomedin-binding proteins produced by rat liver cells in culture. Endocrinology (1979) 1.38
Extreme insulin resistance in ataxia telangiectasia: defect in affinity of insulin receptors. N Engl J Med (1978) 1.37
Gene induction and categorical reprogramming during in vitro human endometrial fibroblast decidualization. Physiol Genomics (2001) 1.35
The purification and characterization of L-histidine ammonia-lyse (Pseudomonas). J Biol Chem (1969) 1.34
The type I insulin-like growth factor receptor is a motility receptor in human melanoma cells. J Biol Chem (1989) 1.31
The serum half-life of somatomedin activity: evidence for growth hormone dependence. Acta Endocrinol (Copenh) (1976) 1.28
Specific binding of a somatomedin-like polypeptide in rat serum depends on growth hormone. Nature (1976) 1.24
Effects of insulin and multiplication-stimulating activity on proteoglycan biosynthesis in chondrocytes from the Swarm rat chondrosarcoma. J Biol Chem (1981) 1.23
Insulin inhibits the activation of transcription by a C-terminal fragment of the forkhead transcription factor FKHR. A mechanism for insulin inhibition of insulin-like growth factor-binding protein-1 transcription. J Biol Chem (2000) 1.21
Identification of a receptor for somatomedin-like polypeptides in human fibroblasts. J Clin Endocrinol Metab (1977) 1.19
Forkhead transcription factor FOXO1A is critical for induction of human decidualization. J Endocrinol (2006) 1.19
Insulin receptors in cultured human fibroblasts. Diabetes (1976) 1.18
Progesterone-dependent decidualization of the human endometrium is mediated by cAMP. Endocrine (1997) 1.17
Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance. J Clin Invest (1990) 1.17
The intercistronic divide: translation of an intercistronic region in the histidine operon of Salmonella typhimurium. Nature (1970) 1.14
Biochemical evidence that the type II insulin-like growth factor receptor is identical to the cation-independent mannose 6-phosphate receptor. J Biol Chem (1988) 1.13
Three clustered Sp1 sites are required for efficient transcription of the TATA-less promoter of the gene for insulin-like growth factor-binding protein-2 from the rat. J Biol Chem (1993) 1.12
The NSILA-s receptor in liver plasma membranes. Characterization and comparison with the insulin receptor. J Biol Chem (1975) 1.11
An antibody that blocks insulin-like growth factor (IGF) binding to the type II IGF receptor is neither an agonist nor an inhibitor of IGF-stimulated biologic responses in L6 myoblasts. J Biol Chem (1987) 1.11
Purified human somatomedin A and rat multiplication stimulating activity. Mitogens for cultured fibroblasts that cross-react with the same growth peptide receptors. Eur J Biochem (1978) 1.10
Insulin-like growth factor-I (IGF-I) stimulates tyrosine kinase activity in purified receptors from a rat liver cell line. Biochem Biophys Res Commun (1984) 1.09
A case of leprechaunism with severe hyperinsulinemia. Am J Dis Child (1980) 1.08
Comparative in vitro activities of teicoplanin, daptomycin, ramoplanin, vancomycin, and PD127,391 against blood isolates of gram-positive cocci. Antimicrob Agents Chemother (1992) 1.08
Multiplication-stimulating activity (MSA): a somatomedin-like polypeptide from cultured rat liver cells. Natl Cancer Inst Monogr (1978) 1.07
X-linked hypogammaglobulinemia and isolated growth hormone deficiency. N Engl J Med (1980) 1.07
Immunological cross-reactivity of multiplication-stimulating activity polypeptides. Eur J Biochem (1980) 1.05
Conjugative mobilization of a vancomycin resistance plasmid by a putative Enterococcus faecium sex pheromone response plasmid. Microb Drug Resist (1995) 1.05
Insulin rapidly decreases insulin-like growth factor-binding protein-1 gene transcription in streptozotocin-diabetic rats. Mol Endocrinol (1992) 1.05
Characterization of a somatomedin (insulin-like growth factor) synthesized by fetal rat liver organ cultures. J Biol Chem (1979) 1.05
Receptors for insulinlike growth factor I are defective in fibroblasts cultured from a patient with leprechaunism. J Clin Invest (1981) 1.04
Cell-free synthesis of rat insulin-like growth factor II. Diabetes (1982) 1.02
Primary defect of insulin receptors in skin fibroblasts cultured from an infant with leprechaunism and insulin resistance. Proc Natl Acad Sci U S A (1979) 1.02
Insulin-induced increase in insulin binding to cultured chondrosarcoma chondrocytes. J Biol Chem (1983) 1.02
Antibiotic tolerance among clinical isolates of bacteria. Annu Rev Pharmacol Toxicol (1985) 1.02
Microarray analysis of trophoblast differentiation: gene expression reprogramming in key gene function categories. Physiol Genomics (2001) 1.01
A new member of the ras gene superfamily identified in a rat liver cell line. Nucleic Acids Res (1988) 1.01
Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the beta-subunit of type I insulin-like growth factor receptors of rat liver cells. J Biol Chem (1985) 1.01
Structure and expression of the rat insulin-like growth factor II (rIGF-II) gene. rIGF-II RNAs are transcribed from two promoters. J Biol Chem (1986) 1.01
Peptidoglycan composition of vancomycin-resistant Enterococcus faecium. Microb Drug Resist (1996) 1.00
Interactions between the receptors for insulin and the insulin-like growth factors on adipocytes. J Biol Chem (1982) 1.00
Prolactin synthesis by human chorion-decidual tissue: a possible source of prolactin in the amniotic fluid. Science (1978) 1.00
Developmental expression of the tissue insulin-like growth factor II/mannose 6-phosphate receptor in the rat. Measurement by quantitative immunoblotting. J Biol Chem (1989) 0.99
Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6. J Biol Chem (1993) 0.99
Properties of a fused protein formed by genetic manipulation. Histidinol dehydrogenase-imidazolylacetol phosphate: L-glutamate aminotransferase. J Biol Chem (1971) 0.98
Antireceptor antibodies as probes of insulinlike growth factor receptor structure. J Clin Invest (1983) 0.98
Interaction of multiplication-stimulating activity with chick embryo fibroblasts demonstrates a growth receptor. Nature (1976) 0.98
Purification of an insulin-like growth factor II receptor from rat chondrosarcoma cells. J Biol Chem (1983) 0.98
Prostaglandin E2 enhances human endometrial stromal cell differentiation. Endocrinology (1994) 0.98
Insulin-like growth factors and diabetes. Diabetes Metab Rev (1992) 0.98
Amino-acid sequence of human placental lactogen. Nat New Biol (1971) 0.98
Multiplication stimulating activity (MSA) from the BRL 3A rat liver cell line: relation to human somatomedins and insulin. J Supramol Struct Cell Biochem (1981) 0.98