Published in J Immunol on October 01, 1983
Identification of a membrane-associated interleukin 1 in macrophages. Proc Natl Acad Sci U S A (1985) 3.39
Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1. J Exp Med (1985) 2.84
Interleukin 1 of the central nervous system is produced by ameboid microglia. J Exp Med (1986) 2.62
Identification and partial characterization of hepatocyte-stimulating factor from leukemia cell lines: comparison with interleukin 1. Proc Natl Acad Sci U S A (1985) 1.68
Cyclic AMP--an intracellular second messenger for interleukin 1. Proc Natl Acad Sci U S A (1988) 1.45
Purification and partial biochemical characterization of normal human interleukin 1. J Exp Med (1984) 1.40
The murine interleukin 1 beta gene: structure and evolution. Nucleic Acids Res (1986) 1.09
Interleukin 1 can act as a B-cell growth and differentiation factor. Proc Natl Acad Sci U S A (1985) 1.08
Single cell studies on the role of B-cell stimulatory factor 1 in B-cell activation. Proc Natl Acad Sci U S A (1987) 0.91
Structure-function analysis of murine interleukin 1: biologically active polypeptides are at least 127 amino acids long and are derived from the carboxyl terminus of a 270-amino acid precursor. Proc Natl Acad Sci U S A (1986) 0.86
Characterization and specificity of a high titre polyclonal goat anti-murine IL-1 antibody. Immunology (1986) 0.80
Characterization of a monoclonal antibody directed against the biologically active site of human interleukin 1. J Exp Med (1986) 0.79
Interleukin-1 production by immunologically hyporeactive tumour-bearing mice. Br J Cancer (1990) 0.78
The effects of interleukins and other soluble factors on T-lymphocyte colony formation. Immunology (1986) 0.78
Specific absorption with monoclonal antibodies to muramyl dipeptide of the pyrogenic and somnogenic activities of rabbit monokine. Proc Natl Acad Sci U S A (1984) 0.78
Cloning and expression of murine interleukin-1 cDNA in Escherichia coli. Nature (1985) 9.81
Interleukin 1, a potential regulator of fibroblast proliferation. J Immunol (1982) 6.05
Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J Immunol (1984) 5.51
Characterization of lymphocyte-activating factor (LAF) produced by the macrophage cell line, P388D1. I. Enhancement of LAF production by activated T lymphocytes. J Immunol (1978) 5.36
Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I. Science (1987) 5.22
Interleukin 1 and T cell activation. Immunol Rev (1982) 5.00
Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1). Proc Natl Acad Sci U S A (1981) 4.89
In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C. Mol Cell Biol (1989) 3.87
Identification of a membrane-associated interleukin 1 in macrophages. Proc Natl Acad Sci U S A (1985) 3.39
Purification to apparent homogeneity of murine interleukin 1. J Immunol (1981) 3.33
Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein. Nature (1988) 3.31
Induction of interleukin 2 messenger RNA inhibited by cyclosporin A. Science (1984) 3.17
Interaction of drugs with microtubule proteins. Fed Proc (1974) 3.14
A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors. Nature (1987) 3.00
Pretranslational modulation of acute phase hepatic protein synthesis by murine recombinant interleukin 1 (IL-1) and purified human IL-1. J Exp Med (1985) 2.84
Nucleoside transport in mammalian cells. Inhibition by colchicine. Biochemistry (1972) 2.70
The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen. Cell Immunol (1981) 2.60
T-Cell lymphoma model for the analysis of interleukin 1-mediated T-cell activation. Proc Natl Acad Sci U S A (1981) 2.51
How does interleukin 1 activate cells? Cyclic AMP and interleukin 1 signal transduction. Immunol Today (1990) 2.48
Interleukin 1 and cyclic AMP induce kappa immunoglobulin light-chain expression via activation of an NF-kappa B-like DNA-binding protein. Mol Cell Biol (1989) 2.28
Studies on the purification and structure-functional relationships of murine lymphocyte activating factor (Interleukin 1). Mol Immunol (1980) 2.28
Signal requirements for T lymphocyte activation. I. Replacement of macrophage function with phorbol myristic acetate. J Immunol (1979) 2.27
Recombinant human interleukin 1 alpha: purification and biological characterization. J Immunol (1986) 2.24
In vivo inflammatory activity of epidermal cell-derived thymocyte activating factor and recombinant interleukin 1 in the mouse. J Clin Invest (1986) 2.22
Interleukin 1 alpha and interleukin 1 beta bind to the same receptor on T cells. J Immunol (1986) 2.14
Inhibition of the transport of several hexoses in mammalian cells by cytochalasin B. J Biol Chem (1972) 2.05
Macrophage-independent activation of helper T cells. I. Production of Interleukin 2. J Immunol (1980) 1.96
The participation of macrophages and macrophage cell lines in the activation of T lymphocytes by mitogens. Immunol Rev (1978) 1.94
Studies on the role of lymphocyte-activating factor (Interleukin 1) in antigen-induced lymph node lymphocyte proliferation. Cell Immunol (1980) 1.92
Characterization of lymphocyte-activating factor (LAF) produced by a macrophage cell line, P388D1. II. Biochemical characterization of LAF induced by activated T cells and LPS. J Immunol (1978) 1.92
Immunoregulatory molecules and IL 2 receptors identified in multiple sclerosis brain. J Immunol (1986) 1.87
Studies on the synthesis and secretion of interleukin 1. I. A 33,000 molecular weight precursor for interleukin 1. J Immunol (1985) 1.86
Phorbol myristic acetate stimulates LAF production by the macrophage cell line, P388D. Cell Immunol (1978) 1.86
Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein. J Immunol (1987) 1.83
Structure and expression of the human FHIT gene in normal and tumor cells. Cancer Res (1997) 1.76
Physicochemical characterization of lymphocyte-activating factor (LAF). J Immunol (1979) 1.76
A clinical trial of creatine in ALS. Neurology (2004) 1.73
Salmonella flagellin induces tumor necrosis factor alpha in a human promonocytic cell line. Infect Immun (1998) 1.72
Participation of lymphocyte activating factor (Interleukin 1) in the induction of cytotoxic T cell responses. J Immunol (1980) 1.72
Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase. Proc Natl Acad Sci U S A (2000) 1.70
High-affinity interaction between gram-negative flagellin and a cell surface polypeptide results in human monocyte activation. Infect Immun (2000) 1.70
Role of interleukin 1 in anti-immunoglobulin-induced B cell proliferation. J Exp Med (1983) 1.69
Regulation of class III major histocompatibility complex gene products by interleukin-1. Science (1986) 1.65
Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells. J Clin Invest (1988) 1.56
Expression of interleukin-1 alpha and beta genes by human blood polymorphonuclear leukocytes. J Clin Invest (1991) 1.54
Evidence for multiple loci from a genome scan of autism kindreds. Mol Psychiatry (2006) 1.52
The interleukin 1 receptor. Dynamics of interleukin 1 binding and internalization in T cells and fibroblasts. J Immunol (1987) 1.49
Cyclic AMP--an intracellular second messenger for interleukin 1. Proc Natl Acad Sci U S A (1988) 1.45
Revised nomenclature for antigen-nonspecific T-cell proliferation and helper factors. Cell Immunol (1979) 1.44
Hypoxia-ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn striatum. Ann Neurol (1997) 1.39
One more pelvic exam. Hastings Cent Rep (1994) 1.39
Characterization of lymphocyte-activating factor (LAF) produced by human mononuclear cells: biochemical relationship of high and low molecular weight forms of LAF. J Immunol (1979) 1.38
Interleukin 1-mediated induction of kappa-light chain synthesis and surface immunoglobulin expression on pre-B cells. J Immunol (1984) 1.34
Progranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes. J Neurol Neurosurg Psychiatry (2007) 1.28
Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor. J Biol Chem (1991) 1.24
Induction of cytokine synthesis by flagella from gram-negative bacteria may be dependent on the activation or differentiation state of human monocytes. Infect Immun (1999) 1.21
Characterization of the human interleukin 1 receptor on human polymorphonuclear leukocytes. Clin Immunol Immunopathol (1988) 1.20
Regulation of lymphocyte-activating factor (LAF) production and secretion in P388D1 cells: identification of high molecular weight precursors of LAF. J Immunol (1979) 1.19
Salmonellae activate tumor necrosis factor alpha production in a human promonocytic cell line via a released polypeptide. Infect Immun (1997) 1.09
Stimulation of fibroblast proliferation and prostaglandin production by purified recombinant murine interleukin 1. Clin Immunol Immunopathol (1986) 1.09
Induction of interleukin 2 responsiveness in thymocytes by synergistic action of interleukin 1 and interleukin 2. J Immunol (1985) 1.05
In vitro T cell-mediated killing of Pseudomonas aeruginosa. II. The role of macrophages and T cell subsets in T cell killing. J Immunol (1985) 1.05
Coronary artery disease: metabolic risk factors and latent disease in individuals with paraplegia. Mt Sinai J Med (1992) 1.04
IL-1 secretion by macrophages. Enhancement of IL-1 secretion and processing by calcium ionophores. J Immunol (1990) 1.04
Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin. Infect Immun (2001) 1.03
Differential effect of cytochalasin B on the two possible modes of 2-deoxyglucose transport in HeLa cells. Nat New Biol (1973) 1.03
Regulation of lipoprotein lipase synthesis and 3T3-L1 adipocyte metabolism by recombinant interleukin 1. Biochim Biophys Acta (1986) 1.02
I-A-positive nonlymphoid cells and T cell development in murine fetal thymus organ cultures: interleukin 1 circumvents the block in T cell differentiation induced by monoclonal anti-I-A antibodies. J Immunol (1986) 1.01
Differential sensitivity of interleukin-1 alpha and -beta precursor proteins to cleavage by calpain, a calcium-dependent protease. J Biol Chem (1995) 1.00
Cytotoxicity by matrix metalloprotease-1 in organotypic spinal cord and dissociated neuronal cultures. Exp Neurol (2000) 0.99
Interleukin-1 beta secretion. A possible multistep process that is regulated in a cell type-specific manner. J Biol Chem (1995) 0.99
Clinical trials of riluzole in patients with ALS. ALS/Riluzole Study Group-II. Neurology (1996) 0.99
Detection of IL-1 alpha and IL-1 beta in the supernatants of paraformaldehyde-treated human monocytes. Evidence against a membrane form of IL-1. J Immunol (1990) 0.95
GABA and hypothalamic feeding systems. I. Topographic analysis of the effects of microinjections of muscimol. Physiol Behav (1979) 0.94
Signal transduction pathway for IL-1. Involvement of a pertussis toxin-sensitive GTP-binding protein in the activation of adenylate cyclase. J Immunol (1989) 0.94
Down-regulation of interleukin 1 production by macrophages of sarcoma-bearing mice. J Immunol (1987) 0.93
Involvement of cyclic AMP-dependent protein kinases in the signal transduction pathway for interleukin-1. Mol Cell Biol (1990) 0.93
Activation of AP-1 by IL-1 and phorbol esters in T cells. Role of protein kinase A and protein phosphatases. J Immunol (1991) 0.90
mRNA and protein stability regulate the differential expression of pro- and anti-inflammatory genes in endotoxin-tolerant THP-1 cells. J Biol Chem (2000) 0.89
Characterization of the structural requirements and cell type specificity of IL-1 alpha and IL-1 beta secretion. J Biol Chem (1993) 0.88
Relationship of optic neuritis to disease of the paranasal sinuses. Laryngoscope (1984) 0.88
Disparate functional properties of two interleukin 1-responsive Ly-1+2- T cell clones: distinction of T cell growth factor and T cell-replacing factor activities. J Immunol (1983) 0.86
Biochemical and biological characterization of lymphocyte-activating factor (LAF) produced by the murine macrophage cell line, P388D. Ann N Y Acad Sci (1979) 0.86
Structure-function analysis of murine interleukin 1: biologically active polypeptides are at least 127 amino acids long and are derived from the carboxyl terminus of a 270-amino acid precursor. Proc Natl Acad Sci U S A (1986) 0.86
Generation of human peripheral blood stable E-rosette-forming T cells by interleukin 1. Clin Immunol Immunopathol (1981) 0.86
Studies on the action of nerve growth factor. I. Characterization of a simplified in vitro culture system for dorsal root and sympathetic ganglia. Dev Biol (1976) 0.85
Evidence against the existence of a membrane form of murine IL-1 alpha. J Immunol (1989) 0.84
IL 1 requirement for B cell activation revealed by use of adult serum. J Immunol (1984) 0.83
Ambulatory tonsillectomy and adenoidectomy: complications and associated factors. J Otolaryngol (1993) 0.81
Proteasome-mediated regulation of interleukin-1beta turnover and export in human monocytes. J Leukoc Biol (2000) 0.80
In vitro production of immunosuppressive factors by murine sarcoma virus-transformed mouse fibroblasts. Proc Natl Acad Sci U S A (1980) 0.80
Mixed cavernous and capillary hemangioma of the frontal bone. Ear Nose Throat J (1985) 0.79
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Molecular signals in antigen presentation. II. Activation of cytolytic cells in vitro after ultraviolet radiation or combined gamma and ultraviolet radiation treatment of antigen-presenting cells. J Immunol (1984) 0.79
Molecular signals in antigen presentation. I. Effects of interleukin 1 and 2 on radiation-treated antigen-presenting cells in vivo and in vitro. Clin Immunol Immunopathol (1983) 0.79
Murine interleukin 1. Methods Enzymol (1985) 0.79