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A Laupacis

Author PubWeight™ 195.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet 2013 8.16
2 The Canadian CT Head Rule for patients with minor head injury. Lancet 2001 7.91
3 Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications. Arch Intern Med 1995 7.83
4 The Canadian C-spine rule for radiography in alert and stable trauma patients. JAMA 2001 7.48
5 Canadian Atrial Fibrillation Anticoagulation (CAFA) Study. J Am Coll Cardiol 1991 6.55
6 The practice guidelines development cycle: a conceptual tool for practice guidelines development and implementation. J Clin Oncol 1995 6.08
7 A patient decision aid regarding antithrombotic therapy for stroke prevention in atrial fibrillation: a randomized controlled trial. JAMA 1999 4.31
8 A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement. N Engl J Med 1993 3.67
9 Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset. Science 1984 3.47
10 Decision aids for patients considering options affecting cancer outcomes: evidence of efficacy and policy implications. J Natl Cancer Inst Monogr 1999 3.45
11 Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2007 3.28
12 The Ottawa patient decision aids. Eff Clin Pract 1999 3.22
13 Assessing the quality of randomized trials: reliability of the Jadad scale. Control Clin Trials 1999 2.99
14 Evidence-based medicine and the practicing clinician. J Gen Intern Med 1999 2.99
15 Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest 1992 2.81
16 Variation in emergency department use of cervical spine radiography for alert, stable trauma patients. CMAJ 1997 2.79
17 Antithrombotic therapy in atrial fibrillation. Chest 2001 2.62
18 Users' Guides to the Medical Literature: XIX. Applying clinical trial results B. Guidelines for determining whether a drug is exerting (more than) a class effect. JAMA 1999 2.54
19 Clinical recommendations using levels of evidence for antithrombotic agents. Chest 1995 2.52
20 Multicentre trial to introduce the Ottawa ankle rules for use of radiography in acute ankle injuries. Multicentre Ankle Rule Study Group. BMJ 1995 2.50
21 Perioperative allogeneic blood transfusion does not cause adverse sequelae in patients with cancer: a meta-analysis of unconfounded studies. Br J Surg 1998 2.44
22 The rational clinical examination. Does this patient have a clinically important carotid bruit? JAMA 1993 2.38
23 Dictated versus database-generated discharge summaries: a randomized clinical trial. CMAJ 1999 2.28
24 What is the quality of life for survivors of cardiac arrest? A prospective study. Acad Emerg Med 1999 2.27
25 Initiating, conducting and maintaining guidelines development programs. CMAJ 1993 2.24
26 Antithrombotic therapy in atrial fibrillation. Chest 1992 2.21
27 A cumulative meta-analysis of the effectiveness of defibrillator-capable emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med 1999 2.19
28 Warfarin for atrial fibrillation. The patient's perspective. Arch Intern Med 1996 2.18
29 Antithrombotic therapy in atrial fibrillation. Chest 1995 2.08
30 Choosing antithrombotic therapy for elderly patients with atrial fibrillation who are at risk for falls. Arch Intern Med 1999 2.07
31 Use of statins and the subsequent development of deep vein thrombosis. Arch Intern Med 2001 1.82
32 Preoperative autologous donation decreases allogeneic transfusion but increases exposure to all red blood cell transfusion: results of a meta-analysis. International Study of Perioperative Transfusion (ISPOT) Investigators. Arch Intern Med 1998 1.68
33 Evaluation of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites. Br J Clin Pharmacol 1984 1.66
34 The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation). Ann Emerg Med 2001 1.65
35 Evaluation of a decision aid for patients considering autologous blood donation before open-heart surgery. CMAJ 2001 1.54
36 When should hypertension be treated? The different perspectives of Canadian family physicians and patients. CMAJ 2000 1.51
37 Cyclosporin prevents diabetes in BB Wistar rats. Lancet 1983 1.50
38 Asymptomatic Wolff-Parkinson-White. Should we intervene? Circulation 1989 1.47
39 Autologous versus allogeneic transfusion: patients' perceptions and experiences. CMAJ 1999 1.45
40 An economic analysis of the Ottawa knee rule. Ann Emerg Med 1999 1.43
41 Low-dose cyclosporine for the treatment of Crohn's disease. The Canadian Crohn's Relapse Prevention Trial Investigators. N Engl J Med 1994 1.43
42 Randomised study of n of 1 trials versus standard practice. BMJ 1996 1.41
43 A meta-analysis of the effectiveness of cell salvage to minimize perioperative allogeneic blood transfusion in cardiac and orthopedic surgery. International Study of Perioperative Transfusion (ISPOT) Investigators. Anesth Analg 1999 1.40
44 Simplified liquid-chromotographic analysis for cyclosporin A, and comparison with radioimmunoassay. Clin Chem 1983 1.38
45 Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2001 1.37
46 How well is the clinical importance of study results reported? An assessment of randomized controlled trials. CMAJ 2001 1.31
47 Variation in ED use of computed tomography for patients with minor head injury. Ann Emerg Med 1997 1.29
48 Development of a decision aid for atrial fibrillation who are considering antithrombotic therapy. J Gen Intern Med 2000 1.23
49 Cost-effectiveness analysis of potential improvements to emergency medical services for victims of out-of-hospital cardiac arrest. Ann Emerg Med 1996 1.21
50 Awareness and use of the Ottawa ankle and knee rules in 5 countries: can publication alone be enough to change practice? Ann Emerg Med 2001 1.19
51 Does acute normovolemic hemodilution reduce perioperative allogeneic transfusion? A meta-analysis. The International Study of Perioperative Transfusion. Anesth Analg 1998 1.17
52 Effectiveness of emergency medical services for victims of out-of-hospital cardiac arrest: a metaanalysis. Ann Emerg Med 1996 1.15
53 Cost-effectiveness analysis of the Ottawa Ankle Rules. Ann Emerg Med 1995 1.13
54 Cyclosporine for treatment of early type I diabetes: preliminary results. N Engl J Med 1983 1.10
55 A double-blind study of 250 cases comparing cemented with cementless total hip arthroplasty. Cost-effectiveness and its impact on health-related quality of life. Clin Orthop Relat Res 1994 1.10
56 A policy analysis of major decisions relating to Creutzfeldt-Jakob disease and the blood supply. CMAJ 2001 1.10
57 Patient preference-based treatment thresholds and recommendations: a comparison of decision-analytic modeling with the probability-tradeoff technique. Med Decis Making 2001 1.10
58 Cyclosporin A: a powerful immunosuppressant. Can Med Assoc J 1982 1.09
59 Surveying physicians to determine the minimal important difference: implications for sample-size calculation. J Clin Epidemiol 1999 1.06
60 Long-term pulmonary function abnormalities and survival after allogeneic marrow transplantation. Bone Marrow Transplant 2004 1.05
61 Emergency physicians' attitudes toward and use of clinical decision rules for radiography. Acad Emerg Med 1998 1.05
62 Theophylline for irreversible chronic airflow limitation: a randomized study comparing n of 1 trials to standard practice. Chest 1999 1.04
63 A survey of clinician attitudes and management practices in hypertension. J Hum Hypertens 1997 1.04
64 Utilization of technologies to reduce allogeneic blood transfusion in the United States. Transfus Med 2001 1.01
65 Technologies to minimize blood transfusion in cardiac and orthopedic surgery. Results of a practice variation survey in nine countries. International Study of Peri-operative Transfusion (ISPOT) Investigators. Int J Technol Assess Health Care 1999 1.00
66 Association of drug therapy with survival in cardiac arrest: limited role of advanced cardiac life support drugs. Acad Emerg Med 1995 0.98
67 Feasibility, limits and problems of clinical studies in Intensive Care Unit. Minerva Anestesiol 2007 0.96
68 Adverse effects of methods for minimizing perioperative allogeneic transfusion: a critical review of the literature. Transfus Med Rev 1998 0.96
69 Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation. Heart 2002 0.95
70 Desmopressin for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2004 0.95
71 Antiplatelet therapy for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks. Cochrane Database Syst Rev 2000 0.95
72 Cost of allogeneic and autologous blood transfusion in Canada. Canadian Cost of Transfusion Study Group. CMAJ 1996 0.94
73 Economic evaluations of technologies to minimize perioperative transfusion: a systematic review of published studies. International Study of Peri-operative Transfusion (ISPOT) investigators. Transfus Med Rev 1999 0.90
74 Economic analysis of erythropoietin use in orthopaedic surgery. Transfus Med 1999 0.90
75 Canadian CT head rule study for patients with minor head injury: methodology for phase II (validation and economic analysis). Ann Emerg Med 2001 0.90
76 HLA-DR and -DQ eplet mismatches and transplant glomerulopathy: a nested case-control study. Am J Transplant 2014 0.89
77 Interaction between phenytoin and cyclosporine following organ transplantation. Transplantation 1984 0.89
78 The impact of recombinant human erythropoietin on medical care costs for hemodialysis patients in Canada. Soc Sci Med 1992 0.88
79 Towards a better yardstick: the choice of treatment thresholds in hypertension. Can J Cardiol 1998 0.88
80 Platelet-rich plasmapheresis in cardiac surgery: a meta-analysis of the effect on transfusion requirements. J Thorac Cardiovasc Surg 1998 0.88
81 The Ontario trial of active compression-decompression cardiopulmonary resuscitation for in-hospital and prehospital cardiac arrest. JAMA 1996 0.87
82 The Nicolas Andry award: comparative results of cemented and cementless total hip arthroplasty. Clin Orthop Relat Res 1996 0.87
83 Pulmonary function abnormalities after allogeneic marrow transplantation: a systematic review and assessment of an existing predictive instrument. Bone Marrow Transplant 2002 0.87
84 A randomized double-blind study of recombinant human erythropoietin in anaemic hemodialysis patients. Canadian Erythropoietin Study Group. Transplant Proc 1991 0.86
85 Cyclosporine: action, pharmacokinetics, and effect in the BB rat model. Metabolism 1983 0.86
86 What should be included in meta-analyses? An exploration of methodological issues using the ISPOT meta-analyses. Int J Technol Assess Health Care 2000 0.84
87 Erythropoietin for anaemia in haemodialysis patients: results of a maintenance study (the Canadian Erythropoietin Study Group). Nephrol Dial Transplant 1992 0.83
88 How interested is the public in genetic testing for colon cancer susceptibility? Report of a cross-sectional population survey. Cancer Prev Control 1998 0.82
89 A randomized clinical trial comparing cemented to cementless total hip replacement in 250 osteoarthritic patients: the impact on health related quality of life and cost effectiveness. Iowa Orthop J 1994 0.81
90 Use of vascular risk-modifying medications for diabetic patients differs between physician specialties. Diabet Med 2006 0.81
91 Cyclosporin for pulmonary sarcoidosis. Lancet 1984 0.80
92 Indications for computed tomography after minor head injury. Canadian CT Head and Cervical-Spine Study Group. N Engl J Med 2000 0.80
93 Effectiveness of perioperative recombinant human erythropoietin in elective hip replacement. COPES Study Group. Lancet 1993 0.80
94 The validity of survivorship analysis in total joint arthroplasty. J Bone Joint Surg Am 1989 0.80
95 A survey of management practices for isolated systolic hypertension. J Am Geriatr Soc 1997 0.79
96 Fibrous hyperplasia of the gingiva: a side effect of cyclosporin A therapy. Oral Surg Oral Med Oral Pathol 1983 0.79
97 Oral anticoagulants for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks. Cochrane Database Syst Rev 2000 0.79
98 Selective screening for abdominal aortic aneurysm. Chronic Dis Can 1996 0.79
99 Lymphocyte subsets in the allograft recipient: correlation of helper to suppressor ratio with clinical events. Transplant Proc 1982 0.79
100 A meta-analysis of prophylactic endoscopic sclerotherapy for esophageal varices. Am J Gastroenterol 1994 0.78
101 Alternatives to blood transfusion are risky too. CMAJ 1998 0.78
102 Desmopressin for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2001 0.78
103 Effects of immunosuppression with cyclosporine in insulin-dependent diabetes mellitus of recent onset: the Canadian open study at 44 months. Transplant Proc 1988 0.78
104 The use of technologies to minimize exposure to perioperative allogeneic blood transfusion in elective surgery. A survey of Canadian hospitals. Int J Technol Assess Health Care 2000 0.78
105 Recombinant human erythropoietin: factors to consider in cost-benefit analysis. Am J Kidney Dis 1991 0.77
106 Differences in treatment preferences between persons who enrol and do not enrol in a clinical trial. Ann R Coll Physicians Surg Can 2001 0.77
107 Methodological studies of systematic reviews: is there publication bias? Arch Intern Med 1997 0.77
108 Use of acetylsalicylic acid by physicians and in the community. CMAJ 1991 0.77
109 Intraarterial methylprednisolone and heparin (IAT) for the treatment of refractory renal transplant rejection episodes. Transplant Proc 1982 0.77
110 The effect of body warming on the ventilatory response to CO2 in the awake dog. Respir Physiol 1982 0.76
111 The use of technologies to decrease peri-operative allogenic blood transfusion: results of practice variation in Israel. Isr Med Assoc J 2001 0.76
112 Hyperbilirubinaemia and cyclosporin A levels. Lancet 1982 0.76
113 Ethics of n-of-1 trials. Lancet 1995 0.75
114 Preventive therapies: weighing the pros and cons. CMAJ 1996 0.75
115 Using the Ottawa Ankle Rules. Ann Emerg Med 1996 0.75
116 Re: CJ Green, DC Hadorn, K Bassett, A Kazanjian. Anticoagulation in chronic nonvalvular atrial fibrillation: a critical appraisal and meta-analysis. 1997;13:811-5. Can J Cardiol 1998 0.75
117 Hard to swallow test. Arch Neurol 1994 0.75
118 Erythropoietin: a hormone finds a purpose. J Rheumatol 1992 0.75
119 Effects of cyclosporine in recent-onset juvenile type 1 diabetes: impact of age and duration of disease. J Pediatr 1987 0.75
120 Renal allograft survival in the baboon using a pretreatment protocol with cyclosporine. Transplantation 1983 0.75
121 The potential of biotechnology to improve the quality of life of patients with renal failure. Drug Saf 1991 0.75
122 Cost effectiveness of epoetin-alpha to augment preoperative autologous blood donation in elective cardiac surgery. Pharmacoeconomics 2000 0.75
123 Total hip replacement: the case for noncemented femoral fixation because of age. Can J Surg 1995 0.75
124 CT findings in postpartum renal cortical necrosis. J Can Assoc Radiol 1983 0.75