Published in Microbiol Rev on March 01, 1984
DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev (1997) 9.69
Bacterial gene transfer by natural genetic transformation in the environment. Microbiol Rev (1994) 8.52
Oxidative stress responses in Escherichia coli and Salmonella typhimurium. Microbiol Rev (1991) 6.86
Acetone-butanol fermentation revisited. Microbiol Rev (1986) 6.55
Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli. Genetics (2001) 6.29
Starvation-induced cross protection against heat or H2O2 challenge in Escherichia coli. J Bacteriol (1988) 6.18
Induction of proteins in response to low temperature in Escherichia coli. J Bacteriol (1987) 5.55
Differential induction of heat shock, SOS, and oxidation stress regulons and accumulation of nucleotides in Escherichia coli. J Bacteriol (1987) 5.51
Adaptive acidification tolerance response of Salmonella typhimurium. J Bacteriol (1990) 5.36
Hydrogen peroxide-inducible proteins in Salmonella typhimurium overlap with heat shock and other stress proteins. Proc Natl Acad Sci U S A (1986) 5.29
Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria. Microbiol Rev (1986) 4.74
Refinement of tools for targeted gene expression in Drosophila. Genetics (2010) 4.53
RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation. Proc Natl Acad Sci U S A (1988) 4.41
DNA damage-inducible transcripts in mammalian cells. Proc Natl Acad Sci U S A (1988) 4.30
Interactions of bacteriophage and host macromolecules in the growth of bacteriophage lambda. Microbiol Rev (1984) 4.17
RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis. Proc Natl Acad Sci U S A (1988) 4.12
In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome. Proc Natl Acad Sci U S A (1984) 4.09
Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins. Mol Cell Biol (1992) 4.04
Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli. Mol Syst Biol (2007) 3.98
Mutagenesis and stress responses induced in Escherichia coli by hydrogen peroxide. J Bacteriol (1987) 3.94
Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription. Microbiol Mol Biol Rev (1997) 3.90
UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA. Proc Natl Acad Sci U S A (1988) 3.85
Global control in Salmonella typhimurium: two-dimensional electrophoretic analysis of starvation-, anaerobiosis-, and heat shock-inducible proteins. J Bacteriol (1986) 3.77
Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51. Mol Cell Biol (1992) 3.74
Oxygen-dependent mutagenesis in Escherichia coli lacking superoxide dismutase. Proc Natl Acad Sci U S A (1986) 3.73
Mu d-directed lacZ fusions regulated by low pH in Escherichia coli. J Bacteriol (1987) 3.60
Identification and genetic analysis of sbcC mutations in commonly used recBC sbcB strains of Escherichia coli K-12. J Bacteriol (1985) 3.43
A global response induced in Escherichia coli by redox-cycling agents overlaps with that induced by peroxide stress. J Bacteriol (1989) 3.38
Heat shock regulatory gene htpR influences rates of protein degradation and expression of the lon gene in Escherichia coli. Proc Natl Acad Sci U S A (1984) 3.33
Cellular defects caused by deletion of the Escherichia coli dnaK gene indicate roles for heat shock protein in normal metabolism. J Bacteriol (1989) 3.26
The export of the DNA replication inhibitor Microcin B17 provides immunity for the host cell. EMBO J (1988) 3.25
The single-stranded DNA-binding protein of Escherichia coli. Microbiol Rev (1990) 3.21
DNA-damage-inducible (din) loci are transcriptionally activated in competent Bacillus subtilis. Proc Natl Acad Sci U S A (1985) 3.21
Endonuclease IV of Escherichia coli is induced by paraquat. Proc Natl Acad Sci U S A (1987) 3.20
Adaptive mutation: the uses of adversity. Annu Rev Microbiol (1993) 3.17
umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology. Proc Natl Acad Sci U S A (1985) 3.14
Lysine-156 and serine-119 are required for LexA repressor cleavage: a possible mechanism. Proc Natl Acad Sci U S A (1987) 3.04
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis. Proc Natl Acad Sci U S A (1985) 3.01
Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A (2009) 3.01
Site-specific methylases induce the SOS DNA repair response in Escherichia coli. J Bacteriol (1987) 2.94
New recA mutations that dissociate the various RecA protein activities in Escherichia coli provide evidence for an additional role for RecA protein in UV mutagenesis. J Bacteriol (1989) 2.87
Endonuclease III (nth) mutants of Escherichia coli. Proc Natl Acad Sci U S A (1985) 2.72
Specific Saccharomyces cerevisiae genes are expressed in response to DNA-damaging agents. Mol Cell Biol (1985) 2.63
Mutagenic repair in Escherichia coli: products of the recA gene and of the umuD and umuC genes act at different steps in UV-induced mutagenesis. Proc Natl Acad Sci U S A (1985) 2.54
UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'. Proc Natl Acad Sci U S A (1989) 2.52
Genetic analysis of the recG locus of Escherichia coli K-12 and of its role in recombination and DNA repair. J Bacteriol (1991) 2.51
Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. Proc Natl Acad Sci U S A (1987) 2.51
Conjugational recombination in resolvase-deficient ruvC mutants of Escherichia coli K-12 depends on recG. J Bacteriol (1991) 2.49
Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid. Proc Natl Acad Sci U S A (1993) 2.44
Overproduction of FtsZ suppresses sensitivity of lon mutants to division inhibition. J Bacteriol (1986) 2.44
Novel structure of the recA locus of Mycobacterium tuberculosis implies processing of the gene product. J Bacteriol (1991) 2.43
Dual role for Escherichia coli RecA protein in SOS mutagenesis. Proc Natl Acad Sci U S A (1985) 2.43
Saccharomyces cerevisiae 3-methyladenine DNA glycosylase has homology to the AlkA glycosylase of E. coli and is induced in response to DNA alkylation damage. EMBO J (1990) 2.41
Involvement of the activated form of RecA protein in SOS mutagenesis and stable DNA replication in Escherichia coli. Proc Natl Acad Sci U S A (1984) 2.35
Identification and characterization of the mutL and mutS gene products of Salmonella typhimurium LT2. J Bacteriol (1985) 2.32
RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation. EMBO J (1998) 2.32
Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A (1985) 2.30
Identification and characterization of starvation-regulated genetic loci in Salmonella typhimurium by using Mu d-directed lacZ operon fusions. J Bacteriol (1988) 2.26
Cloning of the recA gene of Neisseria gonorrhoeae and construction of gonococcal recA mutants. J Bacteriol (1987) 2.23
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc Natl Acad Sci U S A (1998) 2.22
Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis. Proc Natl Acad Sci U S A (1986) 2.20
Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron. J Bacteriol (1994) 2.19
Cloning and characterization of DNA damage-inducible promoter regions from Bacillus subtilis. J Bacteriol (1991) 2.17
Nucleotide sequence binding specificity of the LexA repressor of Escherichia coli K-12. J Bacteriol (1985) 2.16
Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage. EMBO J (1984) 2.15
Cloning of the Vibrio cholerae recA gene and construction of a Vibrio cholerae recA mutant. J Bacteriol (1986) 2.13
Genetic characterization of the inducible SOS-like system of Bacillus subtilis. J Bacteriol (1984) 2.12
Characterization of a bacteriocinogenic plasmid from Clostridium perfringens and molecular genetic analysis of the bacteriocin-encoding gene. J Bacteriol (1986) 2.12
Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites. Genes Dev (2005) 2.06
A model for a umuDC-dependent prokaryotic DNA damage checkpoint. Proc Natl Acad Sci U S A (1999) 2.06
DNA damage and heat shock dually regulate genes in Saccharomyces cerevisiae. Mol Cell Biol (1986) 2.04
Nucleotide sequencing of the ruv region of Escherichia coli K-12 reveals a LexA regulated operon encoding two genes. Nucleic Acids Res (1988) 2.03
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. Proc Natl Acad Sci U S A (1992) 2.03
LexA cleavage and other self-processing reactions. J Bacteriol (1993) 2.02
A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription. EMBO J (1996) 1.99
Effects of norfloxacin on DNA metabolism in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1986) 1.97
Mutations in ftsZ that confer resistance to SulA affect the interaction of FtsZ with GTP. J Bacteriol (1994) 1.96
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli. Proc Natl Acad Sci U S A (1990) 1.95
RecA protein of Escherichia coli has a third essential role in SOS mutator activity. J Bacteriol (1990) 1.93
The REV1 gene of Saccharomyces cerevisiae: isolation, sequence, and functional analysis. J Bacteriol (1989) 1.93
Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination. J Bacteriol (1988) 1.92
Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB gene. Proc Natl Acad Sci U S A (1986) 1.91
Regulation of RAD54- and RAD52-lacZ gene fusions in Saccharomyces cerevisiae in response to DNA damage. Mol Cell Biol (1987) 1.90
Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli. J Bacteriol (1988) 1.89
Cold sensitivity induced by overproduction of UmuDC in Escherichia coli. J Bacteriol (1985) 1.88
Reversibility of SOS-associated division inhibition in Escherichia coli. J Bacteriol (1986) 1.87
Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response. J Bacteriol (1991) 1.86
Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli. Mol Microbiol (2003) 1.84
Multiple control elements for the uvrC gene unit of Escherichia coli. Nucleic Acids Res (1986) 1.84
The ClpP component of Clp protease is the sigma 32-dependent heat shock protein F21.5. J Bacteriol (1990) 1.82
KorB protein of promiscuous plasmid RP4 recognizes inverted sequence repetitions in regions essential for conjugative plasmid transfer. Nucleic Acids Res (1992) 1.82
DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea. Proc Natl Acad Sci U S A (1987) 1.81
Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis. Proc Natl Acad Sci U S A (1990) 1.79
Distribution of centromere-like parS sites in bacteria: insights from comparative genomics. J Bacteriol (2007) 1.78
Isolation of gene fusions (soi::lacZ) inducible by oxidative stress in Escherichia coli. Proc Natl Acad Sci U S A (1988) 1.76
Repair of the Escherichia coli chromosome after in vivo scission by the EcoRI endonuclease. Proc Natl Acad Sci U S A (1989) 1.76
Targeting of the UmuD, UmuD', and MucA' mutagenesis proteins to DNA by RecA protein. Proc Natl Acad Sci U S A (1993) 1.75
Plaque color method for rapid isolation of novel recA mutants of Escherichia coli K-12: new classes of protease-constitutive recA mutants. J Bacteriol (1985) 1.74
Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coli. Proc Natl Acad Sci U S A (1987) 1.73
Isolation of DNA damage-inducible promoters in Escherichia coli: regulation of polB (dinA), dinG, and dinH by LexA repressor. J Bacteriol (1992) 1.73
Lactose genes fused to exogenous promoters in one step using a Mu-lac bacteriophage: in vivo probe for transcriptional control sequences. Proc Natl Acad Sci U S A (1979) 22.59
Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. Bacteriol Rev (1976) 18.20
The SOS regulatory system of Escherichia coli. Cell (1982) 16.90
Mutants of Escherichia coli K-12 defective in DNA repair and in genetic recombination. Genetics (1966) 15.27
Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday. Cold Spring Harb Symp Quant Biol (1966) 14.57
Recombination deficient mutants of E. coli and other bacteria. Annu Rev Genet (1973) 9.55
Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation. J Mol Biol (1968) 9.04
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals. Proc Natl Acad Sci U S A (1975) 8.66
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. Proc Natl Acad Sci U S A (1980) 7.87
Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli. J Mol Biol (1977) 7.41
An inducible DNA replication-cell division coupling mechanism in E. coli. Nature (1981) 6.89
Prophage induction and cell division in E. coli. III. Mutations sfiA and sfiB restore division in tif and lon strains and permit the expression of mutator properties of tif. Mol Gen Genet (1975) 6.82
DNA repair enzymes. Annu Rev Biochem (1982) 6.68
Cleavage of the Escherichia coli lexA protein by the recA protease. Proc Natl Acad Sci U S A (1980) 6.58
Fidelity of DNA synthesis. Annu Rev Biochem (1982) 6.54
Behavior of lambda bacteriophage in a recombination deficienct strain of Escherichia coli. J Virol (1967) 6.38
Positive regulatory gene for temperature-controlled proteins in Escherichia coli. Biochem Biophys Res Commun (1981) 6.35
Mechanism of action of the lexA gene product. Proc Natl Acad Sci U S A (1981) 6.13
Purified Escherichia coli recA protein catalyzes homologous pairing of superhelical DNA and single-stranded fragments. Proc Natl Acad Sci U S A (1979) 5.91
DNA repair in bacteria and mammalian cells. Annu Rev Biochem (1979) 5.85
A mutant of Escherichia coli showing constitutive expression of the lysogenic induction and error-prone DNA repair pathways. Proc Natl Acad Sci U S A (1977) 5.79
Possible relevance of O-6 alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides. Nature (1969) 5.78
A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region. Cell (1983) 5.74
Isolation of deoxyribonucleic acid methylase mutants of Escherichia coli K-12. J Bacteriol (1973) 5.70
Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet light. Mol Gen Genet (1977) 5.61
Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids. Proc Natl Acad Sci U S A (1975) 5.51
Effects of high levels of DNA adenine methylation on methyl-directed mismatch repair in Escherichia coli. Genetics (1983) 5.43
Transduction studies on the role of a rec+ gene in the ultraviolet induction of prophage lambda. J Mol Biol (1967) 5.42
Escherichia coli recA gene product inactivates phage lambda repressor. Proc Natl Acad Sci U S A (1978) 5.42
A new pathway for DNA repair in Escherichia coli. Nature (1977) 5.37
Methyl-directed repair of DNA base-pair mismatches in vitro. Proc Natl Acad Sci U S A (1983) 5.34
Dominant mutations (lex) in Escherichia coli K-12 which affect radiation sensitivity and frequency of ultraviolet lght-induced mutations. J Bacteriol (1972) 5.27
Proteins required for ultraviolet light and chemical mutagenesis. Identification of the products of the umuC locus of Escherichia coli. J Mol Biol (1983) 5.24
Homology among DNA-binding proteins suggests use of a conserved super-secondary structure. Nature (1982) 5.21
Depurination causes mutations in SOS-induced cells. Proc Natl Acad Sci U S A (1981) 5.19
Proteolytic cleavage of bacteriophage lambda repressor in induction. Proc Natl Acad Sci U S A (1975) 5.16
Induction of Mutations in a Bacterial Virus. Proc Natl Acad Sci U S A (1953) 5.16
Protein degradation in Escherichia coli: the lon gene controls the stability of sulA protein. Proc Natl Acad Sci U S A (1983) 5.06
Prophage induction and cell division in E. coli. I. Further characterization of the thermosensitive mutation tif-1 whose expression mimics the effect of UV irradiation. Mol Gen Genet (1972) 4.85
Protein X is the product of the recA gene of Escherichia coli. Proc Natl Acad Sci U S A (1977) 4.75
DNA synthesis inhibition and the induction of protein X in Escherichia coli. J Mol Biol (1976) 4.65
Initiation of general recombination catalyzed in vitro by the recA protein of Escherichia coli. Proc Natl Acad Sci U S A (1979) 4.62
E. coli recA protein-directed cleavage of phage lambda repressor requires polynucleotide. Nature (1980) 4.47
Inducible repair of oxidative DNA damage in Escherichia coli. Nature (1983) 4.35
SOS repair hypothesis: phenomenology of an inducible DNA repair which is accompanied by mutagenesis. Basic Life Sci (1975) 4.17
Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue. J Biol Chem (1980) 4.16
The product of the lon (capR) gene in Escherichia coli is the ATP-dependent protease, protease La. Proc Natl Acad Sci U S A (1981) 4.10
Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A (1981) 4.09
Sequence determinants of promoter activity. Cell (1982) 4.00
Purified lexA protein is a repressor of the recA and lexA genes. Proc Natl Acad Sci U S A (1981) 3.88
The biochemistry of mutagenesis. Annu Rev Biochem (1976) 3.85
Identification of the recA (tif) gene product of Escherichia coli. Proc Natl Acad Sci U S A (1977) 3.75
Role of sulA and sulB in filamentation by lon mutants of Escherichia coli K-12. J Bacteriol (1981) 3.75
Molecular cloning and expression of a gene that controls the high-temperature regulon of Escherichia coli. J Bacteriol (1983) 3.74
Thermal enhancement of ultraviolet mutability in a tif-1 uvrA derivative of Escherichia coli B-r: evidence that ultraviolet mutagenesis depends upon an inducible function. Proc Natl Acad Sci U S A (1974) 3.65
UV-induced mutation hotspots occur at DNA damage hotspots. Nature (1982) 3.63
ATP hydrolysis-dependent protease activity of the lon (capR) protein of Escherichia coli K-12. Proc Natl Acad Sci U S A (1981) 3.61
Nucleotide sequence of the lexA gene of E. coli. Cell (1981) 3.61
Inactivation and proteolytic cleavage of phage lambda repressor in vitro in an ATP-dependent reaction. Proc Natl Acad Sci U S A (1977) 3.47
Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion. Proc Natl Acad Sci U S A (1976) 3.46
Model for regulation of Escherichia coli DNA repair functions. Proc Natl Acad Sci U S A (1975) 3.32
Identification of a novel genetic element in Escherichia coli K-12. J Bacteriol (1980) 3.26
A determination of mutagen specificity in bacteria using nonsense mutants of bacteriophage T4. J Mol Biol (1967) 3.26
[Prophage induction and cell division in E. coli. II. Linked (recA, zab) and unlinked (lex) suppressors of tif-1-mediated induction and filamentation]. Mol Gen Genet (1972) 3.25
Adaptation to alkylation resistance involves the induction of a DNA glycosylase. Nature (1982) 3.23
Expression of the E. coli uvrA gene is inducible. Nature (1981) 3.18
Plasmid (pKM101)-mediated enhancement of repair and mutagenesis: dependence on chromosomal genes in Escherichia coli K-12. Mol Gen Genet (1977) 3.13
Pleiotropic effect of the rec A gene of Escherichia coli: uncoupling of cell division from deoxyribonucleic acid replication. J Bacteriol (1971) 3.12
Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents. Nature (1982) 3.11
Uvm mutants of Escherichia coli K12 deficient in UV mutagenesis. I. Isolation of uvm mutants and their phenotypical characterization in DNA repair and mutagenesis. Mol Gen Genet (1978) 3.10
Base-change mutagenesis and prophage induction in strains of Escherichia coli with different DNA repair capacities. Genetics (1970) 3.05
Suppression of lex mutations affecting deoxyribonucleic acid repair in Escherichia coli K-12 by closely linked thermosensitive mutations. J Bacteriol (1973) 3.03
The lexA gene product represses its own promoter. Proc Natl Acad Sci U S A (1980) 3.03
Repair of O6-methylguanine in adapted Escherichia coli. Proc Natl Acad Sci U S A (1978) 2.98
Infidelity of DNA synthesis associated with bypass of apurinic sites. Proc Natl Acad Sci U S A (1983) 2.95
Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences. Proc Natl Acad Sci U S A (1981) 2.92
recA-independent general genetic recombination of plasmids. Nature (1981) 2.89
A physical and genetic map of the IncN plasmid R46. Plasmid (1981) 2.86
Ultraviolet reactivation and ultraviolet mutagenesis of lambda in different genetic systems. Virology (1971) 2.83
Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA. Nature (1979) 2.81
New class of enzymes acting on damaged DNA. Nature (1976) 2.79
Identification of the lexA gene product of Escherichia coli K-12. Proc Natl Acad Sci U S A (1979) 2.76
Nucleotide sequence of the lexA gene of Escherichia coli K-12. Nucleic Acids Res (1981) 2.75
The role of DNA polymerase in base substitution mutagenesis on non-instructional templates. Biochimie (1983) 2.74
Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. EMBO J (1982) 2.67
Sites of termination of in vitro DNA synthesis on ultraviolet- and N-acetylaminofluorene-treated phi X174 templates by prokaryotic and eukaryotic DNA polymerases. Proc Natl Acad Sci U S A (1981) 2.66
An Escherichia coli mutant defective in single-strand binding protein is defective in DNA replication. Proc Natl Acad Sci U S A (1979) 2.62
Influence of RecA protein on induced mutagenesis. Biochimie (1983) 2.60
Identification of plasmid (pKM101)-coded proteins involved in mutagenesis and UV resistance. Nature (1982) 2.60
Temperature-induced synthesis of specific proteins in Escherichia coli: evidence for transcriptional control. J Bacteriol (1980) 2.59
Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase. J Biol Chem (1982) 2.56
Control of recA gene RNA in E. coli: regulatory and signal genes. Cell (1980) 2.51
The SOS regulatory system: control of its state by the level of RecA protease. J Mol Biol (1983) 2.50
Base substitution mutations induced by metabolically activated aflatoxin B1. Proc Natl Acad Sci U S A (1983) 2.48
The uvrB gene of Escherichia coli has both lexA-repressed and lexA-independent promoters. Cell (1982) 2.48
An adaptive response of E. coli to low levels of alkylating agent: comparison with previously characterised DNA repair pathways. Mol Gen Genet (1977) 2.45
Damage to DNA induces expression of the ruv gene of Escherichia coli. Mol Gen Genet (1982) 2.42
Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents. J Bacteriol (1979) 2.39
Mutagenesis and repair deficiencies of Escherichia coli umuC mutants are suppressed by the plasmid pKM101. Mol Gen Genet (1979) 2.38
Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro. Biochemistry (1983) 2.38
Site-directed insertion and deletion mutagenesis with cloned fragments in Escherichia coli. J Bacteriol (1985) 12.25
Exopolysaccharide-deficient mutants of Rhizobium meliloti that form ineffective nodules. Proc Natl Acad Sci U S A (1985) 8.70
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. Proc Natl Acad Sci U S A (1980) 7.87
The Y-family of DNA polymerases. Mol Cell (2001) 6.49
Science education. Changing the culture of science education at research universities. Science (2011) 6.17
Symbiotic mutants of Rhizobium meliloti that uncouple plant from bacterial differentiation. Cell (1985) 5.88
Proteins required for ultraviolet light and chemical mutagenesis. Identification of the products of the umuC locus of Escherichia coli. J Mol Biol (1983) 5.24
Inducible DNA repair systems. Annu Rev Biochem (1985) 4.94
General transduction in Rhizobium meliloti. J Bacteriol (1984) 4.49
RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation. Proc Natl Acad Sci U S A (1988) 4.41
Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli. Proc Natl Acad Sci U S A (1981) 4.09
Rhizobium meliloti mutants that fail to succinylate their calcofluor-binding exopolysaccharide are defective in nodule invasion. Cell (1987) 3.87
groEL and dnaK genes of Escherichia coli are induced by UV irradiation and nalidixic acid in an htpR+-dependent fashion. Proc Natl Acad Sci U S A (1984) 3.82
A novel exopolysaccharide can function in place of the calcofluor-binding exopolysaccharide in nodulation of alfalfa by Rhizobium meliloti. Cell (1989) 3.39
Genetic manipulations in Rhizobium meliloti utilizing two new transposon Tn5 derivatives. Mol Gen Genet (1986) 3.38
Cellular defects caused by deletion of the Escherichia coli dnaK gene indicate roles for heat shock protein in normal metabolism. J Bacteriol (1989) 3.26
Escherichia coli dnaK null mutants are inviable at high temperature. J Bacteriol (1987) 3.24
Biosynthesis of succinoglycan, a symbiotically important exopolysaccharide of Rhizobium meliloti. Cell (1993) 3.22
Expression of the E. coli uvrA gene is inducible. Nature (1981) 3.18
umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology. Proc Natl Acad Sci U S A (1985) 3.14
Plasmid (pKM101)-mediated enhancement of repair and mutagenesis: dependence on chromosomal genes in Escherichia coli K-12. Mol Gen Genet (1977) 3.13
Succinoglycan is required for initiation and elongation of infection threads during nodulation of alfalfa by Rhizobium meliloti. J Bacteriol (1998) 3.08
Conjugal transfer system of the IncN plasmid pKM101. J Bacteriol (1985) 3.03
Construction of an Escherichia coli K-12 ada deletion by gene replacement in a recD strain reveals a second methyltransferase that repairs alkylated DNA. J Bacteriol (1988) 3.01
New recA mutations that dissociate the various RecA protein activities in Escherichia coli provide evidence for an additional role for RecA protein in UV mutagenesis. J Bacteriol (1989) 2.87
Degradation of carboxy-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH). Genes Dev (1998) 2.87
T4-induced RNA ligase joins single-stranded oligoribonucleotides. Proc Natl Acad Sci U S A (1975) 2.84
Mutations affecting regulation of methionine biosynthetic genes isolated by use of met-lac fusions. J Bacteriol (1982) 2.71
The SOS response: recent insights into umuDC-dependent mutagenesis and DNA damage tolerance. Annu Rev Genet (2000) 2.61
Identification of plasmid (pKM101)-coded proteins involved in mutagenesis and UV resistance. Nature (1982) 2.60
Genetic analysis of a cluster of genes required for synthesis of the calcofluor-binding exopolysaccharide of Rhizobium meliloti. J Bacteriol (1988) 2.52
Mutagenesis and repair deficiencies of Escherichia coli umuC mutants are suppressed by the plasmid pKM101. Mol Gen Genet (1979) 2.38
Cloning vector system for Corynebacterium glutamicum. J Bacteriol (1985) 2.37
Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities. EMBO J (1991) 2.34
Identification and characterization of the mutL and mutS gene products of Salmonella typhimurium LT2. J Bacteriol (1985) 2.32
Symbiotic loci of Rhizobium meliloti identified by random TnphoA mutagenesis. J Bacteriol (1988) 2.27
Isolation and characterization of Tn5 insertion mutations in the lexA gene of Escherichia coli. J Bacteriol (1983) 2.24
Genes needed for the modification, polymerization, export, and processing of succinoglycan by Rhizobium meliloti: a model for succinoglycan biosynthesis. J Bacteriol (1993) 2.22
Similar requirements of a plant symbiont and a mammalian pathogen for prolonged intracellular survival. Science (2000) 2.21
DnaK as a thermometer: threonine-199 is site of autophosphorylation and is critical for ATPase activity. Proc Natl Acad Sci U S A (1991) 2.20
Rhizobium meliloti mutants that overproduce the R. meliloti acidic calcofluor-binding exopolysaccharide. J Bacteriol (1988) 2.14
A model for a umuDC-dependent prokaryotic DNA damage checkpoint. Proc Natl Acad Sci U S A (1999) 2.06
Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae. J Bacteriol (1988) 2.03
A Rhizobium meliloti homolog of the Escherichia coli peptide-antibiotic transport protein SbmA is essential for bacteroid development. Genes Dev (1993) 2.03
Identification of pKM101-encoded loci specifying potentially lethal gene products. J Bacteriol (1985) 2.00
Mutations altering heat shock specific subunit of RNA polymerase suppress major cellular defects of E. coli mutants lacking the DnaK chaperone. EMBO J (1990) 1.97
Genetic techniques in Rhizobium meliloti. Methods Enzymol (1991) 1.97
Delta dnaK52 mutants of Escherichia coli have defects in chromosome segregation and plasmid maintenance at normal growth temperatures. J Bacteriol (1989) 1.96
Low molecular weight EPS II of Rhizobium meliloti allows nodule invasion in Medicago sativa. Proc Natl Acad Sci U S A (1996) 1.90
Induction and autoregulation of ada, a positively acting element regulating the response of Escherichia coli K-12 to methylating agents. J Bacteriol (1985) 1.88
Cold sensitivity induced by overproduction of UmuDC in Escherichia coli. J Bacteriol (1985) 1.88
Functional organization of plasmid pKM101. J Bacteriol (1981) 1.87
Localization of the plasmid (pKM101) gene(s) involved in recA+lexA+-dependent mutagenesis. Mol Gen Genet (1980) 1.85
Mud(Ap, lac)-generated fusions in studies of gene expression. Methods Enzymol (1983) 1.85
Phasmid vectors for identification of genes by complementation of Escherichia coli mutants. J Bacteriol (1985) 1.84
Family of glycosyl transferases needed for the synthesis of succinoglycan by Rhizobium meliloti. J Bacteriol (1993) 1.81
Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis. Proc Natl Acad Sci U S A (1990) 1.79
Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombination. Proc Natl Acad Sci U S A (2001) 1.78
Detailed structural characterization of succinoglycan, the major exopolysaccharide of Rhizobium meliloti Rm1021. J Bacteriol (1994) 1.76
Characterization of an endonuclease associated with the drug resistance plasmid pKM101. J Bacteriol (1977) 1.75
Succinoglycan production by Rhizobium meliloti is regulated through the ExoS-ChvI two-component regulatory system. J Bacteriol (1998) 1.73
Entry exclusion determinant(s) of IncN plasmid pKM101. J Bacteriol (1985) 1.71
Genetic localization and characterization of a pKM101-coded endonuclease. J Bacteriol (1983) 1.70
The 32-kilobase exp gene cluster of Rhizobium meliloti directing the biosynthesis of galactoglucan: genetic organization and properties of the encoded gene products. J Bacteriol (1997) 1.68
The muc genes of pKM101 are induced by DNA damage. J Bacteriol (1983) 1.68
Regulation of damage-inducible genes in Escherichia coli. J Mol Biol (1982) 1.63
Mutagenesis and more: umuDC and the Escherichia coli SOS response. Genetics (1998) 1.63
The Escherichia coli polB gene, which encodes DNA polymerase II, is regulated by the SOS system. J Bacteriol (1990) 1.56
Rhizobium meliloti exoG and exoJ mutations affect the exoX-exoY system for modulation of exopolysaccharide production. J Bacteriol (1991) 1.56
An introduction to medical imaging with coherent terahertz frequency radiation. Phys Med Biol (2002) 1.54
Alfalfa root nodule invasion efficiency is dependent on Sinorhizobium meliloti polysaccharides. J Bacteriol (2000) 1.54
Exopolysaccharides of Rhizobium: synthesis, regulation and symbiotic function. Trends Genet (1994) 1.53
Rhizobium meliloti exopolysaccharides: synthesis and symbiotic function. Gene (1996) 1.52
Exogenous suppression of the symbiotic deficiencies of Rhizobium meliloti exo mutants. J Bacteriol (1992) 1.49
Restriction endonuclease cleavage map of pKM101: relationship to parental plasmid R46. Mol Gen Genet (1981) 1.44
Structural studies of a novel exopolysaccharide produced by a mutant of Rhizobium meliloti strain Rm1021. Carbohydr Res (1990) 1.42
Visualization of mismatch repair in bacterial cells. Mol Cell (2001) 1.40
The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase. Proc Natl Acad Sci U S A (1999) 1.39
The Ada protein acts as both a positive and a negative modulator of Escherichia coli's response to methylating agents. Proc Natl Acad Sci U S A (1994) 1.39
Host-dependent transposon Tn5-mediated streptomycin resistance. J Bacteriol (1984) 1.39
Regulation of Rhizobium meliloti exo genes in free-living cells and in planta examined by using TnphoA fusions. J Bacteriol (1991) 1.36
Anaerobiosis induces expression of ant, a new Escherichia coli locus with a role in anaerobic electron transport. J Bacteriol (1984) 1.36
Structural characterization of the symbiotically important low-molecular-weight succinoglycan of Sinorhizobium meliloti. J Bacteriol (1999) 1.33
The exoD gene of Rhizobium meliloti encodes a novel function needed for alfalfa nodule invasion. J Bacteriol (1991) 1.33
Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis. Nat Struct Biol (1997) 1.30
groE mutants of Escherichia coli are defective in umuDC-dependent UV mutagenesis. J Bacteriol (1989) 1.29
The Rhizobium meliloti exoK gene and prsD/prsE/exsH genes are components of independent degradative pathways which contribute to production of low-molecular-weight succinoglycan. Mol Microbiol (1997) 1.28
Spontaneous mutators of salmonella typhimurium LT2 generated by insertion of transposable elements. J Bacteriol (1981) 1.27
Biosynthetic control of molecular weight in the polymerization of the octasaccharide subunits of succinoglycan, a symbiotically important exopolysaccharide of Rhizobium meliloti. Proc Natl Acad Sci U S A (1998) 1.26
Nucleotide sequence of the Salmonella typhimurium mutL gene required for mismatch repair: homology of MutL to HexB of Streptococcus pneumoniae and to PMS1 of the yeast Saccharomyces cerevisiae. J Bacteriol (1989) 1.25
DnaK mutants defective in ATPase activity are defective in negative regulation of the heat shock response: expression of mutant DnaK proteins results in filamentation. J Bacteriol (1994) 1.24
The acetyl substituent of succinoglycan is not necessary for alfalfa nodule invasion by Rhizobium meliloti Rm1021. J Bacteriol (1993) 1.23
Genetic analysis of the Rhizobium meliloti bacA gene: functional interchangeability with the Escherichia coli sbmA gene and phenotypes of mutants. J Bacteriol (1997) 1.21
Genetic analyses of DNA repair: inference and extrapolation. Annu Rev Genet (1985) 1.21
Defect in expression of heat-shock proteins at high temperature in xthA mutants. J Bacteriol (1986) 1.20
DnaK, hsp73, and their molten globules. Two different ways heat shock proteins respond to heat. J Biol Chem (1992) 1.19
Fertility inhibition of RP1 by IncN plasmid pKM101. J Bacteriol (1985) 1.19
Isolation and characterization of mutants of the plasmid pKM101 deficient in their ability to enhance mutagenesis and repair. J Bacteriol (1978) 1.19
Thermal resistance of Staphylococcus aureus in milk, whey, and phosphate buffer. Appl Microbiol (1966) 1.18
The exoR gene of Rhizobium meliloti affects RNA levels of other exo genes but lacks homology to known transcriptional regulators. J Bacteriol (1991) 1.17