PubRank

H G Eichler

Author PubWeight™ 163.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans. Antimicrob Agents Chemother 1996 1.83
2 Asthma severity and medical resource utilisation. Eur Respir J 2004 1.74
3 Circadian variation of granulocyte colony stimulating factor levels in man. Br J Haematol 1999 1.65
4 Mucosal tolerance as therapy of type I allergy: intranasal application of recombinant Bet v 1, the major birch pollen allergen, leads to the suppression of allergic immune responses and airway inflammation in sensitized mice. Clin Exp Allergy 2002 1.63
5 Effects of hyperinsulinemia on plasma levels of circulating adhesion molecules. J Clin Endocrinol Metab 2000 1.56
6 Penetration of moxifloxacin into peripheral compartments in humans. Antimicrob Agents Chemother 1999 1.54
7 bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat Med 1998 1.50
8 Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock. Crit Care Med 2001 1.50
9 Acetaminophen has greater antipyretic efficacy than aspirin in endotoxemia: a randomized, double-blind, placebo-controlled trial. Clin Pharmacol Ther 1999 1.50
10 A randomized, placebo-controlled, double-blind crossover study of the effect of pentoxifylline on ocular fundus pulsations. Am J Ophthalmol 1996 1.47
11 Paroxetine decreases platelet serotonin storage and platelet function in human beings. Clin Pharmacol Ther 2000 1.46
12 Effects of erythropoietin on platelet reactivity and thrombopoiesis in humans. Blood 2000 1.45
13 Inhalation scintigraphy with iodine-123-labeled interferon gamma-1b: pulmonary deposition and dose escalation study in healthy volunteers. J Nucl Med 1997 1.44
14 Application of microdialysis to clinical pharmacokinetics in humans. Clin Pharmacol Ther 1995 1.44
15 Hemodynamic effects of parathyroid hormone-related peptide-(1-34) in humans. J Clin Endocrinol Metab 1997 1.42
16 Studies on the effect of short-term oral dihydroergotamine and troxerutin in patients with varicose veins. Clin Pharmacol Ther 1994 1.40
17 Effects of desmopressin on circulating P-selectin. Br J Haematol 1996 1.39
18 Measuring extracellular matrix turnover in the serum of patients with idiopathic or ischemic dilated cardiomyopathy and impact on diagnosis and prognosis. Am J Cardiol 1995 1.34
19 Gastrointestinal transit and 5-ASA release from a new mesalazine extended-release formulation. Aliment Pharmacol Ther 2003 1.25
20 Noninvasive investigations of the normal ocular circulation in humans. Invest Ophthalmol Vis Sci 1998 1.23
21 Evaluation of the Zeiss retinal vessel analyser. Br J Ophthalmol 2000 1.23
22 Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapy. J Clin Invest 1997 1.22
23 The role of serine hydroxymethyltransferase in cell proliferation: DNA synthesis from serine following mitogenic stimulation of lymphocytes. Biosci Rep 1981 1.20
24 Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin. Am J Respir Crit Care Med 1999 1.19
25 Clonidine added to bupivacaine enhances and prolongs analgesia after brachial plexus block via a local mechanism in healthy volunteers. Eur J Anaesthesiol 2004 1.16
26 Surgery and intensive care procedures affect the target site distribution of piperacillin. Crit Care Med 2000 1.16
27 Distribution and antimicrobial activity of ciprofloxacin in human soft tissues. Antimicrob Agents Chemother 1999 1.15
28 5-fluorouracil kinetics in the interstitial tumor space: clinical response in breast cancer patients. Cancer Res 1997 1.13
29 Nitric oxide and ocular blood flow in patients with IDDM. Diabetes 1997 1.11
30 Heparin blunts endotoxin-induced coagulation activation. Circulation 2000 1.09
31 Ocular hemodynamics during isometric exercise. Microvasc Res 2001 1.07
32 Role of NO in the O2 and CO2 responsiveness of cerebral and ocular circulation in humans. Am J Physiol 1997 1.05
33 Penetration of ciprofloxacin into the interstitial space of inflamed foot lesions in non-insulin-dependent diabetes mellitus patients. Antimicrob Agents Chemother 1999 1.04
34 Menstrual cycle-associated changes in blood levels of interleukin-6, alpha1 acid glycoprotein, and C-reactive protein. J Lab Clin Med 1997 1.04
35 The effect of a new specific alpha-amylase inhibitor on post-prandial glucose and insulin excursions in normal subjects and Type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1984 1.03
36 A comparison between laser interferometric measurement of fundus pulsation and pneumotonometric measurement of pulsatile ocular blood flow. 1. Baseline considerations. Eye (Lond) 2000 1.02
37 Studies on the neutralizing effects of protamine on unfractionated and low molecular weight heparin (Fragmin) at the site of activation of the coagulation system in man. Thromb Haemost 1995 1.00
38 The effect of systemic nitric oxide-synthase inhibition on ocular fundus pulsations in man. Exp Eye Res 1997 1.00
39 Reversal of endothelin-1-induced ocular hemodynamic effects by low-dose nifedipine in humans. Clin Pharmacol Ther 1998 1.00
40 Endothelin-1 contributes to hyperoxia-induced vasoconstriction in the human retina. Invest Ophthalmol Vis Sci 2000 0.99
41 A combined in vivo pharmacokinetic-in vitro pharmacodynamic approach to simulate target site pharmacodynamics of antibiotics in humans. J Antimicrob Chemother 2000 0.99
42 Elevated procaspase levels in human melanoma. Melanoma Res 2001 0.99
43 Comparison of three different experimental methods for the assessment of peripheral compartment pharmacokinetics in humans. Life Sci 1998 0.98
44 Gastrointestinal transit and release of 5-aminosalicylic acid from 153Sm-labelled mesalazine pellets vs. tablets in male healthy volunteers. Aliment Pharmacol Ther 2003 0.97
45 Effects of antiglaucoma drugs on ocular hemodynamics in healthy volunteers. Clin Pharmacol Ther 1997 0.96
46 Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model. J Mol Med (Berl) 2001 0.95
47 Sex differences in concentrations of exhaled nitric oxide and plasma nitrate. Life Sci 1996 0.95
48 Effects of changes in intraocular pressure on human ocular haemodynamics. Curr Eye Res 1997 0.95
49 The effect of hyperoxia and hypercapnia on fundus pulsations in the macular and optic disc region in healthy young men. Exp Eye Res 1995 0.94
50 The effect of inhalation of different mixtures of O2 and CO2 on ocular fundus pulsations. Exp Eye Res 1996 0.93
51 Influence of MUC18/MCAM/CD146 expression on human melanoma growth and metastasis in SCID mice. Int J Cancer 1999 0.93
52 Effects of systemic NO synthase inhibition on choroidal and optic nerve head blood flow in healthy subjects. Invest Ophthalmol Vis Sci 2000 0.93
53 Dexamethasone down-regulates the expression of L-selectin on the surface of neutrophils and lymphocytes in humans. Clin Pharmacol Ther 1997 0.92
54 Diclofenac concentrations in defined tissue layers after topical administration. Clin Pharmacol Ther 1997 0.92
55 Paracrine effects of angiotensin-converting-enzyme- and angiotensin-II-receptor- inhibition on transcapillary glucose transport in humans. Life Sci 2000 0.92
56 Effect of moclobemide, a new reversible monoamine oxidase inhibitor, on absorption and pressor effect of tyramine. J Cardiovasc Pharmacol 1988 0.92
57 Age dependence of choroidal blood flow. J Am Geriatr Soc 1998 0.91
58 Effects of endotoxemia on thrombopoiesis in men. Thromb Haemost 1999 0.91
59 Effect of nitric oxide synthase inhibition on renal hemodynamics in humans: reversal by L-arginine. Am J Physiol 1997 0.91
60 Inhibition of prostacyclin and thromboxane A2 generation by low-dose aspirin at the site of plug formation in man in vivo. Circulation 1987 0.91
61 [Accidental fatal formaldehyde poisoning]. Wien Klin Wochenschr 1983 0.91
62 Influence of increased c-Myc expression on the growth characteristics of human melanoma. J Invest Dermatol 1999 0.91
63 Phosphorothioate oligonucleotides reduce melanoma growth in a SCID-hu mouse model by a nonantisense mechanism. Antisense Res Dev 1995 0.90
64 A randomized, double-blind, placebo controlled study on analgesic effects of botulinum toxin A. Neurology 2003 0.90
65 Transdermal penetration of diclofenac after multiple epicutaneous administration. J Rheumatol 1998 0.90
66 Measurement of extracellular fluid carboplatin kinetics in melanoma metastases with microdialysis. Br J Cancer 1996 0.90
67 Acetazolamide-induced cerebral and ocular vasodilation in humans is independent of nitric oxide. Am J Physiol 1999 0.90
68 Pharmacokinetics of tamsulosin in subjects with normal and varying degrees of impaired renal function: an open-label single-dose and multiple-dose study. Eur J Clin Pharmacol 1998 0.89
69 Comparison of non-invasive methods for the assessment of haemodynamic drug effects in healthy male and female volunteers: sex differences in cardiovascular responsiveness. Br J Clin Pharmacol 1995 0.89
70 Hypercapnia-induced cerebral and ocular vasodilation is not altered by glibenclamide in humans. Am J Physiol Regul Integr Comp Physiol 2000 0.89
71 Lepirudin blunts endotoxin-induced coagulation activation. Blood 2000 0.89
72 Key metabolite kinetics in human skeletal muscle during ischaemia and reperfusion: measurement by microdialysis. Eur J Clin Invest 1995 0.89
73 Direct assessment of peripheral pharmacokinetics in humans: comparison between cantharides blister fluid sampling, in vivo microdialysis and saliva sampling. Br J Clin Pharmacol 1998 0.89
74 Activated N-ras contributes to the chemoresistance of human melanoma in severe combined immunodeficiency (SCID) mice by blocking apoptosis. Cancer Res 1997 0.89
75 Comparative effects of verapamil, tiapamil, diltiazem and nifedipine on systemic and splanchnic hemodynamics in man. Int J Clin Pharmacol Ther Toxicol 1987 0.88
76 Effects of 17 beta-estradiol on circulating adhesion molecules. J Clin Endocrinol Metab 1994 0.88
77 Elevated circulating P-selectin in insulin dependent diabetes mellitus. Thromb Haemost 1996 0.88
78 Ocular haemodynamics and colour contrast sensitivity in patients with type 1 diabetes. Br J Ophthalmol 2000 0.87
79 Expediting patients' access to medicines by improving the predictability of drug development and the regulatory approval process. Clin Pharmacol Ther 2010 0.87
80 Gatekeepers and enablers: how drug regulators respond to a challenging and changing environment by moving toward a proactive attitude. Clin Pharmacol Ther 2013 0.87
81 Effects of estradiol on circulating P-selectin. J Clin Endocrinol Metab 1996 0.87
82 Plasma concentrations of free and sulfoconjugated dopamine, epinephrine, and norepinephrine in healthy infants and children. Klin Wochenschr 1989 0.87
83 Retinal blood flow and systemic blood pressure in healthy young subjects. Graefes Arch Clin Exp Ophthalmol 2001 0.86
84 Hemodynamic effects of sublingual nifedipine in acute myocardial infarction. Am J Cardiol 1984 0.86
85 Low-dose aspirin does not lower in vivo platelet activation in healthy smokers. Br J Haematol 1998 0.86
86 Effects of acetazolamide on choroidal blood flow. Stroke 1998 0.86
87 Cerebral and ocular hemodynamic effects of sumatriptan in the nitroglycerin headache model. Clin Pharmacol Ther 1996 0.86
88 A comparison between laser interferometric measurement of fundus pulsation and pneumotonometric measurement of pulsatile ocular blood flow. 2. Effects of changes in pCO2 and pO2 and of isoproterenol. Eye (Lond) 2000 0.86
89 Renal and ocular hemodynamic effects of insulin. Diabetes 1997 0.86
90 Penetration of capecitabine and its metabolites into malignant and healthy tissues of patients with advanced breast cancer. Br J Cancer 2003 0.86
91 Endotoxin-induced activation of the coagulation cascade in humans: effect of acetylsalicylic acid and acetaminophen. Arterioscler Thromb Vasc Biol 1999 0.85
92 Pharmacokinetic-pharmacodynamic profile of systemic nitric oxide-synthase inhibition with L-NMMA in humans. Br J Clin Pharmacol 1999 0.85
93 Interstitial methotrexate kinetics in primary breast cancer lesions. Cancer Res 1998 0.85
94 Differential expression levels of Par-4 in melanoma. Melanoma Res 2001 0.84
95 Target site concentrations after continuous infusion and bolus injection of cefpirome to healthy volunteers. Clin Pharmacol Ther 2000 0.84
96 Reproducibility of skin prick testing with allergen extracts from different manufacturers. Allergy 1988 0.84
97 Exhaled NO during graded changes in inhaled oxygen in man. Thorax 1997 0.84
98 Topical fundus pulsation measurements in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 1998 0.83
99 Relationship between serum and free interstitial concentrations of cefodizime and cefpirome in muscle and subcutaneous adipose tissue of healthy volunteers measured by microdialysis. J Clin Pharmacol 1997 0.83
100 Partial inhibition of nitric oxide synthase primes the stimulated pathway of vWF-secretion in man. Atherosclerosis 2000 0.83
101 Measurement of interstitial muscle glucose and lactate concentrations during an oral glucose tolerance test. Am J Physiol 1996 0.83
102 Comparison of the effects of ketamine and memantine on prolactin and cortisol release in men. a randomized, double-blind, placebo-controlled trial. Neuropsychopharmacology 2001 0.83
103 Effects of exercise on circulating vascular adhesion molecules in healthy men. Immunobiology 1997 0.83
104 Primary defect in alpha-adrenergic responsiveness in patients with varicose veins. Clin Pharmacol Ther 1991 0.83
105 Plasma levels of activated factor VII decrease during the menstrual cycle. Thromb Haemost 1998 0.83
106 Granulocyte colony-stimulating factor (G-CSF) downregulates its receptor (CD114) on neutrophils and induces gelatinase B release in humans. Br J Haematol 2000 0.83
107 Theophylline kinetics in peripheral tissues in vivo in humans. Naunyn Schmiedebergs Arch Pharmacol 1995 0.83
108 Characterization of angiotensin-II effects on cerebral and ocular circulation by noninvasive methods. Br J Clin Pharmacol 1997 0.82
109 Glucocorticoids dose-dependently increase plasma levels of granulocyte colony stimulating factor in man. J Clin Endocrinol Metab 1998 0.82
110 Effects of histamine and nitric oxide synthase inhibition on plasma levels of von Willebrand factor antigen. J Lab Clin Med 1998 0.82
111 Tiapamil, a new calcium antagonist: hemodynamic effects in patients with acute myocardial infarction. Circulation 1985 0.82
112 Role of nitric oxide in hemostatic system activation in vivo in humans. Arterioscler Thromb Vasc Biol 1995 0.82
113 Analysis of microdialysates from cancer patients by capillary electrophoresis. Electrophoresis 1998 0.82
114 Effects of cisplatin on urinary thromboxane B2 excretion. Clin Pharmacol Ther 1995 0.81
115 Thromboxane A2 and prostacyclin generation in the microvasculature of patients with atherosclerosis--effect of low-dose aspirin. Thromb Haemost 1989 0.81
116 Partial blockade of nitric oxide synthase blunts the exercise-induced increase of von Willebrand factor antigen and of factor VIII in man. Thromb Haemost 1997 0.80
117 In vivo clearance of antibody-sensitized human drug carrier erythrocytes. Clin Pharmacol Ther 1986 0.80
118 Nitric oxide synthase inhibition in the histamine headache model. Cephalalgia 1997 0.80
119 Systemic and renal effects of an ET(A) receptor subtype-specific antagonist in healthy subjects. Br J Pharmacol 1998 0.80
120 Effects of testosterone suppression on serum levels of hepatitis B surface antigen and HBV-DNA in men. Liver 1998 0.80
121 Comparison of recombinant timothy grass pollen allergens with natural extract for diagnosis of grass pollen allergy in different populations. J Allergy Clin Immunol 1996 0.80
122 Endotoxin down-modulates granulocyte colony-stimulating factor receptor (CD114) on human neutrophils. J Infect Dis 2000 0.80
123 Effects of endothelin-1 (ET-1) on ocular hemodynamics. Curr Eye Res 1997 0.79
124 Access of HTB, main metabolite of triflusal, to cerebrospinal fluid in healthy volunteers. Eur J Clin Pharmacol 2005 0.79
125 Endothelin-induced venoconstriction is unaffected by type 2-diabetes: in vivo effect of histamine on the endothelin action on veins. Arch Int Pharmacodyn Ther 1992 0.79
126 Systemic NO synthase inhibition blunts the chronotropic, but not the inotropic response to isoprenaline in man. Nitric Oxide 1999 0.79
127 Role of nitric oxide in exercise-induced vasodilation in man. Life Sci 1998 0.79
128 Systemic inflammation increases shear stress-induced platelet plug formation measured by the PFA-100. Br J Haematol 2000 0.79
129 In vivo drug-response measurements in target tissues by microdialysis. Clin Pharmacol Ther 1997 0.79
130 Kit ligand/mast cell growth factor-independent differentiation of mast cells in myelodysplasia and chronic myeloid leukemic blast crisis. Blood 1994 0.79
131 Division of the major birch pollen allergen, Bet v 1, into two non-anaphylactic fragments. Int Arch Allergy Immunol 1997 0.79
132 Influence of angiotensin II on circulating adhesion molecules and blood leukocyte count in vivo. Can J Physiol Pharmacol 1996 0.79
133 Inhibition of paracrine angiotensin-converting enzyme in vivo: effects on interstitial glucose and lactate concentrations in human skeletal muscle. Eur J Clin Invest 1997 0.79
134 Hemodynamic effects of continuous urodilatin infusion: a dose-finding study. Clin Pharmacol Ther 1998 0.78
135 Regulatory review: How do agencies ensure the quality of decision making? Clin Pharmacol Ther 2013 0.78
136 Differential induction of P-selectin expression on platelets by two cell separators during plateletpheresis and the effect of gender on the release of soluble P-selectin. Transfusion 1998 0.78
137 Comparison of the effects of different low molecular weight heparins on the hemostatic system activation in vivo in man. Thromb Haemost 1997 0.78
138 Cardiocirculatory effects of moclobemide (Ro 11-1163), a new reversible, a short-acting MAO-inhibitor with preferential type A inhibition, in healthy volunteers and depressive patients. Eur J Clin Pharmacol 1983 0.78
139 Nifedipine antagonizes alpha-adrenoceptor mediated splanchnic and systemic vasoconstriction in man. Int J Clin Pharmacol Ther Toxicol 1987 0.78
140 Evaluation of mitoxantrone-loaded albumin microspheres following intraperitoneal administration to rats. J Control Release 1999 0.78
141 Micellar electrokinetic chromatography for the analysis of cefpirome in microdialysis and plasma samples obtained in vivo from human volunteers. Electrophoresis 2000 0.78
142 Sex differences in circulating P-selectin, E-selectin and thrombomodulin. Br J Haematol 1996 0.78
143 Effect of ketanserin on phenylephrine-dependent changes in splanchnic hemodynamics and systemic blood pressure in healthy subjects. J Cardiovasc Pharmacol 1985 0.78
144 Survival of gentamicin-loaded carrier erythrocytes in healthy human volunteers. Eur J Clin Invest 1986 0.78
145 Effects of atropine and propranolol on retinal vessel diameters during isometric exercise. Ophthalmic Res 2001 0.78
146 A drug interaction study of ceftriaxone and frusemide in healthy volunteers. Int J Clin Pharmacol Ther Toxicol 1986 0.78
147 In vitro and in vivo studies of three radiolabelled somatostatin analogues: 123I-octreotide (OCT), 123I-Tyr-3-OCT and 111In-DTPA-D-Phe-1-OCT. Eur J Nucl Med 1996 0.78
148 Comparative pharmacokinetics and cardiovascular effects of tiapamil in healthy volunteers and patients with hepatic cirrhosis. Eur J Clin Pharmacol 1986 0.78
149 Effect of calcium antagonists on basal and digitalis-dependent changes in splanchnic and systemic hemodynamics. Clin Pharmacol Ther 1987 0.78
150 Effects of recombinant hirudin (r-hirudin, HBW 023) on coagulation and platelet activation in vivo. Comparison with unfractionated heparin and a low-molecular-weight heparin preparation (fragmin). Arterioscler Thromb Vasc Biol 1995 0.77
151 Effects of insulin on retinal and pulsatile choroidal blood flow in humans. Arch Ophthalmol 2000 0.77
152 Short-term oral pentoxifylline use increases choroidal blood flow in patients with age-related macular degeneration. Arch Ophthalmol 1998 0.77
153 Effects of anticoagulation on thrombopoietin release during endotoxemia. J Lab Clin Med 2001 0.77
154 Effects of heparin and aspirin on circulating P-selectin, E-selectin and von Willebrand Factor levels in healthy men. Atherosclerosis 2001 0.77
155 Moclobemide, a new reversible MAO inhibitor--interaction with tyramine and tricyclic antidepressants in healthy volunteers and depressive patients. Psychopharmacology (Berl) 1986 0.77
156 A double masked placebo controlled study on the effect of nifedipine on optic nerve blood flow and visual field function in patients with open angle glaucoma. Br J Clin Pharmacol 2001 0.77
157 Endomyocardial HLA expression is increased to the same extent in idiopathic and secondary dilated cardiomyopathy. Immunol Lett 1994 0.77
158 Effect of pituitary adenylate cyclase activating polypeptide 1-27 on ocular, cerebral and skin blood flow in humans. Naunyn Schmiedebergs Arch Pharmacol 1998 0.77
159 Effects of a low molecular weight heparin (Fragmin) and of unfractionated heparin on coagulation activation at the site of plug formation in vivo. Thromb Haemost 1994 0.77
160 Renal hemodynamic effects of L-arginine and sodium nitroprusside in heart transplant recipients. Kidney Int 1999 0.77
161 Inhibition rather than enhancement of hemostatic system activation during initiation of oral anticoagulant treatment. Thromb Haemost 1997 0.77
162 In vivo studies on alpha-adrenergic receptor subtypes in human veins. Naunyn Schmiedebergs Arch Pharmacol 1991 0.77
163 Dexamethasone lowers circulating E-selectin and ICAM-1 in healthy men. J Lab Clin Med 2000 0.77
164 Anaphylactic reactions to bee-sting challenges in allergic children are not modified by endogenous catecholamines. Pediatr Res 1995 0.77
165 High-level expression in Escherichia coli and purification of recombinant plant profilins: comparison of IgE-binding capacity and allergenic activity. Biochem Biophys Res Commun 1996 0.77
166 Erythrocytes as carriers for heparin. Preliminary in vitro and animal studies. Res Exp Med (Berl) 1986 0.76
167 Application of the minimal trauma tissue biopsy to transdermal clinical pharmacokinetic studies. J Control Release 2001 0.76
168 Effect of hydroxyethyl starch on the activity of blood coagulation and fibrinolysis in healthy volunteers: comparison with albumin. Crit Care Med 1994 0.76
169 Effects of losartan on cerebral and ocular circulation in healthy subjects. Br J Clin Pharmacol 1997 0.76
170 Recombinant allergens. Steps on the way to diagnosis and therapy of type I allergy. Adv Exp Med Biol 1996 0.76
171 Venous responsiveness to atrial natriuretic factor in man. Br J Clin Pharmacol 1988 0.76
172 Effects of angiotensin-II infusion at pressor and subpressor doses on endothelin-1 plasma levels in healthy men. Life Sci 1997 0.76
173 Release of vitamin B12 from carrier erythrocytes in vitro. Res Exp Med (Berl) 1985 0.76
174 Effects of serotonin and noradrenaline on superficial hand veins in patients with primary hypertension and in healthy volunteers. Naunyn Schmiedebergs Arch Pharmacol 1992 0.76
175 Relationship between in vivo drug exposure of the tumor interstitium and inhibition of tumor cell growth in vitro: a study in breast cancer patients. Breast Cancer Res Treat 2000 0.76
176 Age dependence of perimacular white blood cell flux during isometric exercise. Curr Eye Res 2000 0.75
177 Multicentre clinical trials. Lancet 1999 0.75
178 Evidence against an effect of endothelin-1 on blood coagulation, fibrinolysis, and endothelial cell integrity in healthy men. Arterioscler Thromb Vasc Biol 1997 0.75
179 Diltiazem counteracts digitalis-dependent splanchnic vasoconstriction in man. Int J Clin Pharmacol Ther Toxicol 1987 0.75
180 Exogenous L-arginine does not affect angiotensin II-induced renal vasoconstriction in man. Br J Clin Pharmacol 1998 0.75
181 [Carrier systems for drugs--a new principle in drug therapy?]. Dtsch Med Wochenschr 1985 0.75
182 Is the ECG measure RSh a promising technique for detecting class I antiarrhythmic drug action in men? J Cardiovasc Pharmacol 1995 0.75
183 Ocular and systemic reactivity to isoprenaline in patients with insulin-dependent diabetes mellitus. Eur J Clin Invest 1997 0.75
184 Epinephrine does not impair utilization of exogenous amino acids in humans. Am J Clin Nutr 1997 0.75
185 [Right heart failure as a clinical sign of pulmonary artery sarcoma]. Wien Klin Wochenschr 1987 0.75
186 First-pass uptake of methotrexate after intra-arterial bolus injection in human head and neck cancers. Eur J Clin Invest 1996 0.75
187 Thromboxane A2 does not mediate angiotensin II-dependent nonischemic peripheral vasoconstriction in healthy men: a pilot study. Int J Clin Pharmacol Ther 1997 0.75
188 Tiapamil--a new calcium antagonist. S Afr Med J 1985 0.75
189 Pharmacokinetics of emedastine difumarate, a new anti-histaminic agent in patients with renal impairment. Eur J Clin Pharmacol 2001 0.75
190 Toxicity of a particulate formulation for the intraperitoneal application of mitoxantrone. Int J Pharm 1999 0.75
191 Kinetics of circulating selectin levels during bone marrow aplasia. Eur J Haematol 1998 0.75
192 Does phosphodiesterase III inhibition reverse the cardiodepressive effects of propofol? Anesth Analg 1997 0.75
193 Short-term drug effects on the signal-averaged electrocardiogram in healthy men: assessment of intra- and interindividual variability of spectral temporal mapping and time-domain analysis. J Pharmacol Exp Ther 1995 0.75
194 Initiation of antihypertensive therapy among new users of cyclooxygenase-2-selective and nonselective NSAIDs. Int J Clin Pharmacol Ther 2004 0.75
195 Pharmacokinetics and bioavailability of isosorbide-5-mononitrate in humans. Int J Clin Pharmacol Ther Toxicol 1985 0.75
196 Safety issues of plateletpheresis: comparison of the effects of two cell separators on the activation of coagulation, fibrinolysis, and neutrophils and on the formation of neutrophil-platelet aggregates. Transfusion 1999 0.75
197 Pharmacokinetic and mass balance study of unlabelled and (14)C-labelled emedastine difumarate in healthy volunteers. Xenobiotica 2002 0.75
198 [Interferon alpha 2C in the treatment of 2 patients with AIDS-associated Kaposi sarcoma]. Wien Klin Wochenschr 1987 0.75
199 Nitric oxide concentration in the gas phase of the gastrointestinal tract in man. Eur J Clin Invest 1997 0.75
200 Beta-blockade in acute myocardial infarction: is Swan-Ganz catheterization required before treatment? Int J Clin Pharmacol Ther Toxicol 1987 0.75
201 Validation of urea as an endogenous reference compound for the in vivo calibration of microdialysis probes. Life Sci 2000 0.75
202 Effects of endothelin-1 on circulating adhesion molecules in man. Eur J Clin Invest 1997 0.75
203 Studies on the effect of two angiotensin-converting enzyme inhibitors, captopril and cilazapril, on platelet and vascular prostaglandin metabolism in vivo. Naunyn Schmiedebergs Arch Pharmacol 1992 0.75
204 Effects of nitric oxide on platelet activation during plateletpheresis and in vivo tracking of biotinylated platelets in humans. Transfusion 1999 0.75
205 Effects of neuropeptide Y and vasoactive intestinal peptide on human venous smooth muscle in vivo. Naunyn Schmiedebergs Arch Pharmacol 1994 0.75
206 Phase-I study of intraperitoneal mitoxantrone--clinical and pharmacokinetic evaluation. Onkologie 1987 0.75
207 In vivo study of the effect of exogenous estradiol on alpha-adrenoceptor responsiveness of human veins. J Cardiovasc Pharmacol 1994 0.75
208 Isolated growth hormone deficiency after severe head trauma. J Endocrinol Invest 1988 0.75
209 [Accidental ingestion of corrosives by children (author's transl)]. Padiatr Padol 1981 0.75
210 Heparin lowers plasma levels of activated factor VII. Br J Haematol 1999 0.75
211 Effects of nitroglycerin and sodium nitroprusside on endexpiratory concentrations of nitric oxide in healthy humans. Life Sci 1998 0.75
212 Coupling of mitoxantrone to poly(I).poly(C) reduces absorption after intraperitoneal administration. Chemotherapy 1987 0.75
213 Effect of cianopramine, a tricyclic antidepressant, on platelet serotonin uptake and peripheral adrenergic function. Clin Pharmacol Ther 1984 0.75
214 Poly(I).poly(C), a potential drug carrier for the antitumor agent mitoxantrone: in vitro drug binding study. Cancer Chemother Pharmacol 1987 0.75
215 N-ras oncogene expression changes the growth characteristics of human melanoma in two independent SCID-hu mouse models. Int J Cancer 1996 0.75
216 Penetration of capecitabine and its metabolites into malignant and healthy tissue of patients with advanced breast cancer. Int J Clin Pharmacol Ther 2002 0.75
217 Escalating dose regimen of intraperitoneal mitoxantrone: phase I study--clinical and pharmacokinetic evaluation. Eur J Cancer Clin Oncol 1988 0.75
218 Effects of sodium nitroprusside on hemodialysis-induced platelet activation. Kidney Int 1999 0.75
219 Effect of ritanserin, a 5-hydroxytryptamine2-receptor antagonist, on platelet function and thrombin generation at the site of plug formation in vivo. Clin Pharmacol Ther 1990 0.75
220 Bioequivalence between two furosemide-spironolactone formulations: a pharmacokinetic and pharmacodynamic approach. Curr Med Res Opin 1991 0.75
221 Delayed effect of desmopressin on circulating neutrophils and monocytes. Br J Haematol 1996 0.75
222 Effect of diclofensine, a novel antidepressant, on peripheral adrenergic function. Clin Pharmacol Ther 1986 0.75
223 Hypolipidaemic activity of a novel acyclic ansamycin derivative. Synthesis and pharmacokinetic and pharmacodynamic studies in rodents. Arzneimittelforschung 1992 0.75
224 Cisplatin-induced renal effects and thromboxane A2 receptor blockade. Eur J Clin Invest 1997 0.75
225 Accidental ingestion of NaF tablets by children--report of a poison control center and one case. Int J Clin Pharmacol Ther Toxicol 1982 0.75