Published in J Bacteriol on August 01, 1983
Biosynthesis and metabolism of arginine in bacteria. Microbiol Rev (1986) 5.79
Alanine dehydrogenase (ald) is required for normal sporulation in Bacillus subtilis. J Bacteriol (1993) 1.54
Cloning and sequencing of the major intracellular serine protease gene of Bacillus subtilis. J Bacteriol (1986) 1.39
Activation of intracellular serine proteinase in Bacillus subtilis cells during sporulation. J Bacteriol (1986) 1.08
Energy and calcium ion dependence of proteolysis during sporulation of Bacillus subtilis cells. J Bacteriol (1990) 1.04
Purification, characterization, and physiological function of Bacillus subtilis ornithine transcarbamylase. J Bacteriol (1983) 0.99
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An improved scintillation cocktail of high-solubilizing power. Anal Biochem (1973) 4.39
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Effects of mutational loss of specific intracellular proteases on the sporulation of Bacillus subtilis. J Bacteriol (1973) 1.91
Sporulation of tricarboxylic acid cycle mutants of Bacillus subtilis. J Bacteriol (1972) 1.87
The inactivation of microbial enzymes in vivo. Annu Rev Microbiol (1977) 1.80
Inactivation of aspartic transcarbamylase in sporulating Bacillus subtilis: demonstration of a requirement for metabolic energy. J Bacteriol (1973) 1.58
Immunochemical studies of the inactivation of aspartate transcarbamylase by stationary phase Bacillus subtilis cells. Evidence for selective, energy-dependent degradation. J Biol Chem (1978) 1.46
Oxygen-dependent inactivation of glutamine phosphoribosylpyrophosphate amidotransferase in stationary-phase cultures of Bacillus subtilis. J Bacteriol (1975) 1.37
Characterization of a thermosensitive sporulation mutant of Bacillus subtilis affected in the structural gene of an intracellular protease. Eur J Biochem (1979) 1.24
Intracellular serine protease from Bacillus subtilis. Structural comparison with extracellular serine proteases-subtilisins. Biochem Biophys Res Commun (1977) 1.23
Proteolysis in bacterial sporulation. Curr Top Cell Regul (1980) 1.10
Synthesis and inactivation of carbamyl phosphate synthetase isozymes of Bacillus subtilis during growth and sporulation. J Bacteriol (1979) 1.02
Purification, characterization, and physiological function of Bacillus subtilis ornithine transcarbamylase. J Bacteriol (1983) 0.99
Intracellular serine proteinase of Bacillus subtilis strain Marburg 168. Comparison with the homologous enzyme from Bacillus subtilis strain A-50. Biochem J (1979) 0.97
Degradation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase in vivo. J Biol Chem (1983) 0.97
Regulation of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster by an autogenous transcriptional attenuation mechanism. J Bacteriol (1994) 2.17
Phosphoribosylpyrophosphate synthetase of Escherichia coli. Properties of the purified enzyme and primary structure of the prs gene. J Biol Chem (1986) 2.07
Functional organization and nucleotide sequence of the Bacillus subtilis pyrimidine biosynthetic operon. J Biol Chem (1991) 1.96
Structure of the allosteric regulatory enzyme of purine biosynthesis. Science (1994) 1.81
The inactivation of microbial enzymes in vivo. Annu Rev Microbiol (1977) 1.80
Inactivation of aspartic transcarbamylase in sporulating Bacillus subtilis: demonstration of a requirement for metabolic energy. J Bacteriol (1973) 1.58
Roles of the three transcriptional attenuators of the Bacillus subtilis pyrimidine biosynthetic operon in the regulation of its expression. J Bacteriol (1995) 1.54
Function of RNA secondary structures in transcriptional attenuation of the Bacillus subtilis pyr operon. Proc Natl Acad Sci U S A (1996) 1.47
Immunochemical studies of the inactivation of aspartate transcarbamylase by stationary phase Bacillus subtilis cells. Evidence for selective, energy-dependent degradation. J Biol Chem (1978) 1.46
Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium. J Biol Chem (1969) 1.41
Oxygen-dependent inactivation of glutamine phosphoribosylpyrophosphate amidotransferase in stationary-phase cultures of Bacillus subtilis. J Bacteriol (1975) 1.37
Cloning of the Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase gene in Escherichia coli. Nucleotide sequence determination and properties of the plasmid-encoded enzyme. J Biol Chem (1983) 1.35
Effects of glucose and nitrogen source on the levels of proteinases, peptidases, and proteinase inhibitors in yeast. Biochim Biophys Acta (1977) 1.34
Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR. Nucleic Acids Res (2001) 1.32
Nutritional regulation of degradation of aspartate transcarbamylase and of bulk protein in exponentially growing Bacillus subtilis cells. J Bacteriol (1983) 1.32
Purification and properties of phosphoribosyl-diphosphate synthetase from Bacillus subtilis. Eur J Biochem (1990) 1.30
Adaptation of an enzyme to regulatory function: structure of Bacillus subtilis PyrR, a pyr RNA-binding attenuation protein and uracil phosphoribosyltransferase. Structure (1998) 1.27
The genetic and functional basis of purine nucleotide feedback-resistant phosphoribosylpyrophosphate synthetase superactivity. J Clin Invest (1995) 1.27
Effects of medium quality on the expression of human interleukin-2 at high cell density in fermentor cultures of Escherichia coli K-12. Appl Environ Microbiol (1990) 1.25
Expression of recombinant human hemoglobin in Escherichia coli. Methods Enzymol (1994) 1.24
Transcriptional attenuation of the Bacillus subtilis pyr operon by the PyrR regulatory protein and uridine nucleotides in vitro. J Bacteriol (1996) 1.24
Characterization of pyrimidine-repressible and arginine-repressible carbamyl phosphate synthetases from Bacillus subtilis. J Bacteriol (1979) 1.23
Cloning and structure of the Bacillus subtilis aspartate transcarbamylase gene (pyrB). J Biol Chem (1986) 1.22
Aspartokinase III, a new isozyme in Bacillus subtilis 168. J Bacteriol (1990) 1.19
Regulation and mechanism of phosphoribosylpyrophosphate synthetase: repression by end products. J Bacteriol (1971) 1.18
Characterization of cis-acting mutations in the first attenuator region of the Bacillus subtilis pyr operon that are defective in pyrimidine-mediated regulation of expression. J Bacteriol (1996) 1.16
Aspartate transcarbamylase synthesis ceases prior to inactivation of the enzyme in Bacillus subtilis. J Bacteriol (1978) 1.15
Purification and characterization of Bacillus subtilis PyrR, a bifunctional pyr mRNA-binding attenuation protein/uracil phosphoribosyltransferase. J Biol Chem (1998) 1.13
Regulation and mechanism of phosphoribosylpyrophosphate synthetase. V. Inhibition by end products and regulation by adenosine diphosphate. J Biol Chem (1973) 1.12
Proteolysis in bacterial sporulation. Curr Top Cell Regul (1980) 1.10
Mechanism of the synergistic end-product regulation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase by nucleotides. Biochemistry (1997) 1.10
Regulation of Salmonella phosphoribosylpyrophosphate synthetase activity in vivo. Deductions from pool measurements. J Biol Chem (1977) 1.09
Purification and characterization of the DeoR repressor of Bacillus subtilis. J Bacteriol (2000) 1.07
Purification and properties of Bacillus subtilis aspartate transcarbamylase. J Biol Chem (1975) 1.06
Studies of the quaternary structure and the chemical properties of phosphoribosylpyrophosphate synthetase from Salmonella typhimurium. J Biol Chem (1975) 1.06
Structure of the gene encoding phosphoribosylpyrophosphate synthetase (prsA) in Salmonella typhimurium. J Bacteriol (1988) 1.05
Characterization of the hemA-prs region of the Escherichia coli and Salmonella typhimurium chromosomes: identification of two open reading frames and implications for prs expression. J Gen Microbiol (1993) 1.03
Binding of the substrates and the allosteric inhibitor adenosine 5'-diphosphate to phosphoribosylpyrophosphate synthetase from Salmonella typhimurium. J Biol Chem (1982) 1.03
Reaction of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase with oxygen: chemistry and regulation by ligands. Biochemistry (1981) 1.03
Regulation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase inactivation in vivo. J Bacteriol (1983) 1.03
Regulation of transcription of the Bacillus subtilis pyrG gene, encoding cytidine triphosphate synthetase. J Bacteriol (2001) 1.02
Synthesis and inactivation of carbamyl phosphate synthetase isozymes of Bacillus subtilis during growth and sporulation. J Bacteriol (1979) 1.02
Oxygen-dependent inactivation of glutamine phosphoribosylpyrophosphate amidotransferase in vitro inactivation. J Bacteriol (1975) 1.01
Characterization of the Escherichia coli prsA1-encoded mutant phosphoribosylpyrophosphate synthetase identifies a divalent cation-nucleotide binding site. J Biol Chem (1989) 1.01
Regulation and mechanism of phosphoribosylpyrophosphate synthetase. 3. Kinetic studies of the reaction mechanism. J Biol Chem (1971) 1.01
Coordinate synthesis of the enzymes of pyrimidine biosynthesis in Bacillus subtilis. J Bacteriol (1982) 1.00
Phosphoribosylpyrophosphate synthetase (ribose-5-phosphate pyrophosphokinase) from Salmonella typhimurium. Methods Enzymol (1978) 0.99
Purification, characterization, and physiological function of Bacillus subtilis ornithine transcarbamylase. J Bacteriol (1983) 0.99
The Enterococcus faecalis pyr operon is regulated by autogenous transcriptional attenuation at a single site in the 5' leader. J Bacteriol (1999) 0.99
Involvement of the stringent response in degradation of glutamine phosphoribosylpyrophosphate amidotransferase in Bacillus subtilis. J Bacteriol (1983) 0.97
Improved expression of human interleukin-2 in high-cell-density fermentor cultures of Escherichia coli K-12 by a phosphotransacetylase mutant. Appl Environ Microbiol (1990) 0.97
Degradation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase in vivo. J Biol Chem (1983) 0.97
Specific repression of phosphoribosylpyrophosphate synthetase by uridine compounds in Salmonella typhimurium. J Bacteriol (1972) 0.96
Regulation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase activity by end products. J Biol Chem (1979) 0.96
The defective phosphoribosyl diphosphate synthase in a temperature-sensitive prs-2 mutant of Escherichia coli is compensated by increased enzyme synthesis. Microbiology (1996) 0.96
Evidence that the iron-sulfur cluster of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase determines stability of the enzyme to degradation in vivo. J Biol Chem (1989) 0.96
Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 gene. J Biol Chem (1993) 0.95
Overexpression, purification, and characterization of recombinant human 5-phosphoribosyl-1-pyrophosphate synthetase isozymes I and II. J Biol Chem (1993) 0.95
Structure of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster. J Bacteriol (1987) 0.95
Evidence for substrate stabilization in regulation of the degradation of Bacillus subtilis aspartate transcarbamylase in vivo. Arch Biochem Biophys (1995) 0.95
Oxidation-reduction properties of the iron-sulfur cluster in Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase. J Biol Chem (1983) 0.94
Apparent inactivation of inosine 5'-monophosphate dehydrogenase in sporulating Bacillus subtilis Is an artifact of in vitro proteolysis. J Bacteriol (1975) 0.94
Evidence that the Bacillus subtilis pyrimidine regulatory protein PyrR acts by binding to pyr mRNA at three sites in vivo. J Bacteriol (1996) 0.93
Involvement of the stringent response in regulation of protein degradation in Bacillus subtilis. Curr Top Cell Regul (1985) 0.93
Purification and properties of glutamine phosphoribosylpyrophosphate amidotransferase from Bacillus subtilis. Biochemistry (1981) 0.93
Mutant strains of Salmonella typhimurium with defective phosphoribosylpyrophosphate synthetase activity. J Gen Microbiol (1982) 0.91
Mutations in Bacillus subtilis PyrR, the pyr regulatory protein, with defects in regulation by pyrimidines. FEMS Microbiol Lett (1996) 0.89
Evidence for a tetranuclear iron-sulfur center in glutamine phosphoribosylpyrophosphate amidotransferase from Bacillus subtilis. J Biol Chem (1980) 0.89
Identification of a novel gene of pyrimidine nucleotide biosynthesis, pyrDII, that is required for dihydroorotate dehydrogenase activity in Bacillus subtilis. J Bacteriol (1996) 0.88
Inhibition of human 5-phosphoribosyl-1-pyrophosphate synthetase by 4-amino-8-(beta-D-ribofuranosylamino)-pyrimido[5,4-d]pyrimidine-5'- monophosphate: evidence for interaction at the ADP allosteric site. Mol Pharmacol (1995) 0.87
Chemical modification of Salmonella typhimurium phosphoribosylpyrophosphate synthetase with 5'-(p-fluorosulfonylbenzoyl)adenosine. Identification of an active site histidine. J Biol Chem (1990) 0.87
Intracellular serine protease 1 of Bacillus subtilis is formed in vivo as an unprocessed, active protease in stationary cells. J Bacteriol (1990) 0.87
The degA gene product accelerates degradation of Bacillus subtilis phosphoribosylpyrophosphate amidotransferase in Escherichia coli. J Bacteriol (1993) 0.87
The glutamine-utilizing site of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase. J Biol Chem (1983) 0.86
Oxygen-18 studies of the mechanism of pyrophosphoryl group transfer catalyzed by phosphoribosylpyrophosphate synthetase. Arch Biochem Biophys (1975) 0.86
Glutamine phosphoribosylpyrophosphate amidotransferase from Bacillus subtilis. A novel iron-sulfur protein. J Biol Chem (1977) 0.85
Hydrogen transfer between substrates and deoxyadenosylcobalamin in the glutamate mutase reaction. J Biol Chem (1969) 0.85
Spectroscopic characterization of the iron-sulfur cluster in Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase. J Biol Chem (1989) 0.84
Aspartate transcarbamylase from Bacillus subtilis. Methods Enzymol (1985) 0.84
Enzymatic activity and - 32 P labeling of fluorescent derivatives of cytidine triphosphate and adenosine triphosphate. J Am Chem Soc (1973) 0.84
prsB is an allele of the Salmonella typhimurium prsA gene: characterization of a mutant phosphoribosylpyrophosphate synthetase. J Bacteriol (1991) 0.84
Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme. Biochem Med (1974) 0.83
Purification and characterization of component S of glutamate mutase. J Biol Chem (1967) 0.83
Conformation of MgATP bound to 5-phospho-alpha-D-ribose 1-diphosphate synthetase by two-dimensional transferred nuclear Overhauser effect spectroscopy. Eur J Biochem (1995) 0.82
Stereochemistry of the glutamate mutase reaction. J Biol Chem (1966) 0.81
Regulation and mechanism of phosphoribosylpyrophosphate synthetase. II. Excchange reactions catalyzed by the enzyme. J Biol Chem (1970) 0.80
Aspartokinase II from Bacillus subtilis is degraded in response to nutrient limitation. J Biol Chem (1990) 0.80
Stimulation of enzyme synthesis by sublethal concentrations of chloramphenicol is not mediated by ribonucleotide pools. Antimicrob Agents Chemother (1975) 0.80
Mechanism of phosphoribosylpyrophosphate synthetase: evidence for an enzyme-pyrophosphate intermediate. Biochem Biophys Res Commun (1968) 0.80
In vitro stabilization of 6-methylsalicylic acid synthetase from Penicillium urticae. Can J Microbiol (1988) 0.80
Biochemical characterization of the heteromeric Bacillus subtilis dihydroorotate dehydrogenase and its isolated subunits. Arch Biochem Biophys (1999) 0.79
Evidence against formation of a pyrophosphoryl enzyme intermediate in the phosphoribosylpyrophosphate synthetase reaction. J Biol Chem (1974) 0.79
Inactivation of Salmonella phosphoribosylpyrophosphate synthetase by oxidation of a specific sulfhydryl group with potassium permanganate. J Biol Chem (1975) 0.79
Structure of the divalent cation.nucleotide complex at the active site of phosphoribosylpyrophosphate synthetase. J Biol Chem (1980) 0.78
Studies of the stereochemistry and of the role of metal ions in the mechanism of phosphoribosylpyrophosphate synthetase from Salmonella typhimurium. J Biol Chem (1978) 0.78
Point mutations in PRPS1, the gene encoding the PRPP synthetase (PRS) 1 isoform, underlie X-linked PRS superactivity associated with purine nucleotide inhibitor-resistance. Adv Exp Med Biol (1994) 0.78
Sulfhydryl chemistry of Salmonella typhimurium phosphoribosylpyrophosphate synthetase: identification of two classes of cysteinyl residues. Arch Biochem Biophys (1990) 0.76
Degradation of aspartate transcarbamylase in Bacillus subtilis is deficient in rel mutants but is not mediated by guanosine polyphosphates. J Bacteriol (1984) 0.76
Kinetic and magnetic resonance studies of the interaction of the Cr-ATP complex with phosphoribosylpyrophosphate synthetase from Salmonella typhimurium. Arch Biochem Biophys (1979) 0.75