PubRank

R R Reddel

Author PubWeight™ 109.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 1997 6.55
2 Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 1995 6.03
3 Telomere maintenance by recombination in human cells. Nat Genet 2000 5.14
4 Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body. Cancer Res 1999 4.24
5 Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. Hum Mol Genet 1997 3.56
6 Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme. Lancet 2003 2.26
7 Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells. Mol Cell Biol 2001 1.99
8 The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit. Hum Mol Genet 1997 1.97
9 Establishment and characterization of SV40 T-antigen immortalized human esophageal epithelial cells. Cancer Res 1991 1.88
10 Telomere dynamics and telomerase activity in in vitro immortalised human cells. Eur J Cancer 1997 1.87
11 Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts. Mol Cell Biol 1995 1.85
12 Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function. Cancer Res 2000 1.70
13 Human bronchial epithelial cells with integrated SV40 virus T antigen genes retain the ability to undergo squamous differentiation. Differentiation 1988 1.64
14 The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity. Neoplasia 2001 1.60
15 SV40-induced immortalization of human cells. Crit Rev Oncog 1994 1.51
16 Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma. Am J Pathol 1989 1.51
17 Tamoxifen induces accumulation of MCF 7 human mammary carcinoma cells in the G0/G1 phase of the cell cycle. Eur J Cancer Clin Oncol 1983 1.49
18 Telomere length dynamics in telomerase-positive immortal human cell populations. Exp Cell Res 1998 1.47
19 Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells. Cancer Res 1998 1.45
20 Telomere maintenance mechanisms and cellular immortalization. Curr Opin Genet Dev 1999 1.43
21 Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member. J Biol Chem 1998 1.43
22 Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference. Oncogene 2007 1.42
23 Strontium phosphate transfection of human cells in primary culture: stable expression of the simian virus 40 large-T-antigen gene in primary human bronchial epithelial cells. Mol Cell Biol 1987 1.39
24 Differential sensitivity of human breast cancer cell lines to the growth-inhibitory effects of tamoxifen. Cancer Res 1985 1.37
25 Ototoxicity in patients receiving cisplatin: importance of dose and method of drug administration. Cancer Treat Rep 1982 1.37
26 Mammalian stanniocalcins and cancer. Endocr Relat Cancer 2003 1.35
27 Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids. Oncogene 1999 1.34
28 Methylation of the human telomerase gene CpG island. Cancer Res 2000 1.31
29 A novel human cDNA highly homologous to the fish hormone stanniocalcin. Mol Cell Endocrinol 1995 1.30
30 Comparison of production of transforming growth factor-beta and platelet-derived growth factor by normal human mesothelial cells and mesothelioma cell lines. Cancer Res 1987 1.30
31 Characteristics of tumor cell bioactivity in oncogenic osteomalacia. Mol Cell Endocrinol 1996 1.25
32 Stanniocalcin 1 and 2 are secreted as phosphoproteins from human fibrosarcoma cells. Biochem J 2000 1.10
33 Correction of the copper transport defect of Menkes patient fibroblasts by expression of the Menkes and Wilson ATPases. J Biol Chem 1998 1.10
34 Assignment of SV40-immortalized cells to more than one complementation group for immortalization. Exp Cell Res 1993 1.10
35 p16(INK4a) and the control of cellular proliferative life span. Carcinogenesis 1999 1.08
36 Malignant transformation of NIH3T3 cells by overexpression of mot-2 protein. Oncogene 1998 1.03
37 Effects of biologically active metabolites of tamoxifen on the proliferation kinetics of MCF-7 human breast cancer cells in vitro. Cancer Res 1983 1.02
38 Germ-line splicing mutation of the p53 gene in a cancer-prone family. Cell Growth Differ 1992 1.01
39 A highly expressed 81 kDa protein in immortalized mouse fibroblast: its proliferative function and identity with ezrin. Oncogene 1996 1.00
40 Identification of a second stanniocalcin cDNA in mouse and human: stanniocalcin 2. Mol Cell Endocrinol 1998 0.98
41 Effects of oestrogens on cell proliferation and cell cycle kinetics. A hypothesis on the cell cycle effects of antioestrogens. Eur J Cancer Clin Oncol 1983 0.97
42 Neoplastic transformation of a human bronchial epithelial cell line by a recombinant retrovirus encoding viral Harvey ras. Mol Carcinog 1988 0.97
43 Factors affecting the sensitivity of T-47D human breast cancer cells to tamoxifen. Cancer Res 1984 0.96
44 In vitro transformation of Li-Fraumeni syndrome fibroblasts by SV40 large T antigen mutants. Oncogene 1994 0.95
45 Association of extended in vitro proliferative potential with loss of p16INK4 expression. Oncogene 1996 0.95
46 Stanniocalcin-1 acts in a negative feedback loop in the prosurvival ERK1/2 signaling pathway during oxidative stress. Oncogene 2009 0.95
47 An N-terminal region of mot-2 binds to p53 in vitro. Neoplasia 2001 0.95
48 Finite life span of hybrids formed by fusion of different simian virus 40-immortalized human cell lines. J Virol 1992 0.94
49 HPV-16 E6 and E7 genes, like SV40 early region genes, are insufficient for immortalization of human mesothelial and bronchial epithelial cells. Exp Cell Res 1994 0.94
50 Correlation between complementation group for immortality and the cellular distribution of mortalin. Exp Cell Res 1995 0.93
51 Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway. J Biol Chem 2001 0.90
52 Involvement of RB-1, p53, p16INK4 and telomerase in immortalisation of human cells. Oncogene 1995 0.90
53 Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression. Exp Cell Res 2001 0.90
54 Transformation of human neonatal prostate epithelial cells by strontium phosphate transfection with a plasmid containing SV40 early region genes. Cancer Res 1989 0.89
55 Similar simian virus 40-induced immortalization frequency of fibroblasts and epithelial cells from human large airways. Cell Mol Biol Res 1993 0.88
56 Normal telomere maintenance in immortal ataxia telangiectasia cell lines. Mutat Res 1997 0.87
57 Identification of a 55-kDa ezrin-related protein that induces cytoskeletal changes and localizes to the nucleolus. Exp Cell Res 1999 0.86
58 Downregulation of metallothionein-IIA expression occurs at immortalization. Oncogene 1999 0.86
59 Molecular cloning and characterization of mouse stanniocalcin cDNA. Mol Cell Endocrinol 1996 0.86
60 The distribution of stanniocalcin 1 protein in fetal mouse tissues suggests a role in bone and muscle development. J Endocrinol 2000 0.85
61 Invasive and metastatic potential of a v-Ha-ras-transformed human bronchial epithelial cell line. J Natl Cancer Inst 1989 0.85
62 Inhibition of SV40 large T antigen induced apoptosis by small T antigen. Oncogene 1999 0.85
63 Tamoxifen stimulation of human breast cancer cell proliferation in vitro: a possible model for tamoxifen tumour flare. Eur J Cancer Clin Oncol 1984 0.85
64 Control of growth and squamous differentiation in normal human bronchial epithelial cells by chemical and biological modifiers and transferred genes. Environ Health Perspect 1989 0.84
65 Human mesothelioma cells and asbestos-exposed mesothelial cells are selectively resistant to amosite toxicity: a possible mechanism for tumor promotion by asbestos. Carcinogenesis 1992 0.84
66 Structurally and functionally distinct mouse hsp70 family members Mot-1 and Mot-2 proteins are encoded by two alleles. DNA Res 2000 0.83
67 Constructing immortalized human cell lines. Curr Opin Biotechnol 1999 0.81
68 Cloning and characterization of a novel gene, striamin, that interacts with the tumor suppressor protein p53. J Biol Chem 1999 0.80
69 Stanniocalcin 1 is important for poststroke functionality, but dispensable for ischemic tolerance. Neuroscience 2012 0.80
70 Upregulation of survivin during immortalization of nontransformed human fibroblasts transduced with telomerase reverse transcriptase. Oncogene 2009 0.79
71 Transcriptional inactivation of p53 by deletions and single amino acid changes in mouse mot-1 protein. Biochem Biophys Res Commun 2000 0.79
72 Effects of exogenous wild-type p53 on a human lung carcinoma cell line with endogenous wild-type p53. Exp Cell Res 1992 0.79
73 Cell cycle effects of iron depletion on T-47D human breast cancer cells. Exp Cell Res 1985 0.79
74 Genetic changes associated with immortalization. A review. Biochemistry (Mosc) 1997 0.79
75 Replicative cultures of adult human and rhesus monkey liver epithelial cells. Cancer Detect Prev 1989 0.78
76 Expression and localisation of stanniocalcin 1 in rat bladder, kidney and ovary. Electrophoresis 1999 0.78
77 Telomeres and cell division potential. Prog Mol Subcell Biol 2000 0.78
78 Differential display of mRNA. Mol Biotechnol 1998 0.77
79 Surgery in patients with advanced germ cell malignancy following a clinical partial response to chemotherapy. J Surg Oncol 1983 0.76
80 Genetic differences between the pancytosolic and perinuclear forms of murine mortalin. Exp Cell Res 1996 0.76
81 N-desmethyltamoxifen inhibits growth of MCF 7 human mammary carcinoma cells in vitro. Eur J Cancer Clin Oncol 1983 0.76
82 Chromosomal changes and progressive tumorigenesis of human bronchial epithelial cell lines. Cancer Genet Cytogenet 1996 0.75
83 Reassessment of immortalization complementation group D. Exp Gerontol 1998 0.75
84 Human stanniocalcin (STC): genomic structure, chromosomal localization, and the presence of CAG trinucleotide repeats. Genomics 1998 0.75
85 Identification of a novel human mitochondrial D-loop RNA species which exhibits upregulated expression following cellular immortalization. Biochem Biophys Res Commun 2000 0.75
86 An effective elimination of false positives isolated from differential display of mRNAs. Mol Biotechnol 1996 0.75
87 Induction of anchorage independent growth and serum resistance in immortalized human bronchial epithelial cells by alteration of the cytoskeleton. Cell Mol Biol Res 1994 0.75