Published in Mol Gen Genet on January 01, 1983
Nucleotide sequence and transcriptional analysis of the redD locus of Streptomyces coelicolor A3(2). J Bacteriol (1990) 1.92
Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius. J Bacteriol (1992) 1.91
Characterization of the pathway-specific positive transcriptional regulator for actinorhodin biosynthesis in Streptomyces coelicolor A3(2) as a DNA-binding protein. J Bacteriol (1999) 1.68
bldA dependence of undecylprodigiosin production in Streptomyces coelicolor A3(2) involves a pathway-specific regulatory cascade. J Bacteriol (1997) 1.65
Construction and application of a promoter-probe plasmid that allows chromogenic identification in Streptomyces lividans. J Bacteriol (1985) 1.42
Gene organization and structure of the Streptomyces lividans gal operon. J Bacteriol (1988) 1.36
Cloning genes for the biosynthesis of a macrolide antibiotic. Proc Natl Acad Sci U S A (1987) 1.35
abaA, a new pleiotropic regulatory locus for antibiotic production in Streptomyces coelicolor. J Bacteriol (1992) 1.31
Efficient plasmid transformation of Streptomyces ambofaciens and Streptomyces fradiae protoplasts. J Bacteriol (1985) 1.27
Transcriptional regulation of bialaphos biosynthesis in Streptomyces hygroscopicus. J Bacteriol (1987) 1.26
The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster. J Bacteriol (1999) 1.16
The level of a transcript required for production of a Streptomyces coelicolor antibiotic is conditionally dependent on a tRNA gene. J Bacteriol (1990) 1.08
Streptomyces coelicolor A3(2) lacks a genomic island present in the chromosome of Streptomyces lividans 66. Appl Environ Microbiol (2004) 0.99
Streptomyces cloning: useful recombinant DNA systems and a summation of cloned genes. Antimicrob Agents Chemother (1988) 0.95
Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways. J Ind Microbiol Biotechnol (2013) 0.95
A silent ABC transporter isolated from Streptomyces rochei F20 induces multidrug resistance. J Bacteriol (1998) 0.87
Genome sequence of the cycloprodigiosin-producing bacterial strain Pseudoalteromonas rubra ATCC 29570(T). J Bacteriol (2012) 0.84
Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3(2). BMC Syst Biol (2012) 0.80
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature (2002) 19.35
Cloning and expression of the tyrosinase gene from Streptomyces antibioticus in Streptomyces lividans. J Gen Microbiol (1983) 6.44
Plasmids, recombination and chromosome mapping in Streptomyces lividans 66. J Gen Microbiol (1983) 5.06
pIJ101, a multi-copy broad host-range Streptomyces plasmid: functional analysis and development of DNA cloning vectors. Mol Gen Genet (1982) 5.02
A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome. Mol Microbiol (1996) 4.81
Genetic analysis and genome structure in Streptomyces coelicolor. Bacteriol Rev (1967) 4.78
Genetic studies with bacterial protoplasts. Annu Rev Microbiol (1981) 4.05
Gene cloning in Streptomyces. Curr Top Microbiol Immunol (1982) 3.95
Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host. Nature (1984) 3.61
DNA cloning in Streptomyces: resistance genes from antibiotic-producing species. Nature (1980) 3.36
The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces. Cell (1991) 3.32
Transformation of plasmid DNA into Streptomyces at high frequency. Nature (1978) 3.27
Engineered biosynthesis of novel polyketides. Science (1993) 3.16
Cloning of antibiotic resistance and nutritional genes in streptomycetes. J Bacteriol (1982) 3.06
Mutangenesis by N-methyl-N'-nitro-N-nitrosoguanidine (NTG) in Streptomyces coelicolor. Mutat Res (1970) 2.88
Physical analysis of antibiotic-resistance genes from Streptomyces and their use in vector construction. Gene (1982) 2.81
Chromosomal recombination and mapping in Rhizobium leguminosarum. Nature (1976) 2.78
Nucleotide sequence, transcription and deduced function of a gene involved in polyketide antibiotic synthesis in Streptomyces coelicolor. Gene (1988) 2.68
Physical and genetic characterisation of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2). Mol Gen Genet (1986) 2.61
Advances in Streptomyces coelicolor genetics. Bacteriol Rev (1973) 2.57
Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits. Nature (1995) 2.56
The Streptomyces plasmid SCP2*: its functional analysis and development into useful cloning vectors. Gene (1985) 2.46
The chromosomal DNA of Streptomyces lividans 66 is linear. Mol Microbiol (1993) 2.34
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22. EMBO J (1989) 2.30
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin. J Biol Chem (1992) 2.21
Genetic recombination through protoplast fusion in Streptomyces. Nature (1977) 2.14
Genetics of actinorhodin biosynthesis by Streptomyces coelicolor A3(2). J Gen Microbiol (1979) 2.13
Production of actinorhodin-related "blue pigments" by Streptomyces coelicolor A3(2). J Bacteriol (1996) 2.07
Production of 'hybrid' antibiotics by genetic engineering. Nature (1985) 2.04
Nucleotide sequence and transcriptional analysis of the redD locus of Streptomyces coelicolor A3(2). J Bacteriol (1990) 1.92
Excision of chromosomal DNA sequences from Streptomyces coelicolor forms a novel family of plasmids detectable in Streptomyces lividans. Mol Gen Genet (1981) 1.88
A combined genetic and physical map of the Streptomyces coelicolor A3(2) chromosome. J Bacteriol (1992) 1.85
Site-specific degradation of Streptomyces lividans DNA during electrophoresis in buffers contaminated with ferrous iron. Nucleic Acids Res (1988) 1.83
Identification of the antibiotic determined by the SCP1 plasmid of Streptomyces coelicolor A3(2). J Gen Microbiol (1976) 1.81
Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli. 3. Repression of enzymes of arginine biosynthesis in arginyl-tRNA synthetase mutants. J Mol Biol (1968) 1.80
Bacterial protoplast fusion: recombination in fused protoplasts of Streptomyces coelicolor. Mol Gen Genet (1978) 1.79
Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans. Genetics (2000) 1.75
Biochemical characterization of resistance determinants cloned from antibiotic-producing streptomycetes. J Bacteriol (1982) 1.70
Genetic and biochemical characterization of the red gene cluster of Streptomyces coelicolor A3(2). J Gen Microbiol (1985) 1.68
A pigmented mycelial antibiotic in Streptomyces coelicolor: control by a chromosomal gene cluster. J Gen Microbiol (1980) 1.65
Isolation of covalently closed circular deoxyribonucleic acid from Streptomyces coelicolor A3(2). J Bacteriol (1975) 1.63
Septation during sporulation in Streptomyces coelicolor. J Gen Microbiol (1970) 1.61
Mutants of Streptomyces coelicolor defective in sporulation. J Gen Microbiol (1970) 1.59
Increasing incidence of Barrett's oesophagus: education, enthusiasm, or epidemiology? Lancet (1997) 1.57
Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase. Proc Natl Acad Sci U S A (1994) 1.54
Organisation and functions of the actVA region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor. Mol Gen Genet (1991) 1.47
Genetic determination of methylenomycin synthesis by the SCP1 plasmid of Streptomyces coelicolor A3(2). J Gen Microbiol (1977) 1.46
Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis. FEMS Microbiol Lett (1999) 1.45
DNA sequence and functions of the actVI region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor A3(2). J Biol Chem (1994) 1.41
Actinorhodin is a chromosomally-determined antibiotic in Streptomyces coelicolar A3(2). J Gen Microbiol (1976) 1.40
Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2). Biochemistry (1997) 1.35
Cloning and expression of Mycobacterium bovis BCG DNA in "Streptomyces lividans". J Bacteriol (1986) 1.35
The linkage map of Streptomyces rimosus. J Gen Microbiol (1971) 1.34
Plasmid and phage vectors for gene cloning and analysis in Streptomyces. Methods Enzymol (1987) 1.34
Integrated DNA sequences in three streptomycetes form related autonomous plasmids after transfer to Streptomyces lividans. Plasmid (1984) 1.34
Targeted gene replacements in a Streptomyces polyketide synthase gene cluster: role for the acyl carrier protein. Mol Microbiol (1992) 1.33
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin. Gene (1994) 1.31
abaA, a new pleiotropic regulatory locus for antibiotic production in Streptomyces coelicolor. J Bacteriol (1992) 1.31
Genetic manipulation of Streptomyces: integrating vectors and gene replacement. Methods Enzymol (1991) 1.31
Discovery of an insertion sequence, IS116, from Streptomyces clavuligerus and its relatedness to other transposable elements from actinomycetes. J Gen Microbiol (1990) 1.30
Cloning and expression in a heterologous host of the complete set of genes for biosynthesis of the Streptomyces coelicolor antibiotic undecylprodigiosin. Gene (1990) 1.30
Activity of a Streptomyces transcriptional terminator in Escherichia coli. Nucleic Acids Res (1987) 1.27
A new channel-forming antibiotic from Streptomyces coelicolor A3(2) which requires calcium for its activity. J Gen Microbiol (1983) 1.27
Genetics of antibiotic production. Bacteriol Rev (1977) 1.27
Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins. J Bacteriol (1993) 1.27
The conjugative plasmid SLP2 of Streptomyces lividans is a 50 kb linear molecule. Mol Microbiol (1993) 1.26
Cloning and expression of a puromycin N-acetyl transferase gene from Streptomyces alboniger in Streptomyces lividans and Escherichia coli. Gene (1985) 1.26
Ectopic expression of the Streptomyces coelicolor whiE genes for polyketide spore pigment synthesis and their interaction with the act genes for actinorhodin biosynthesis. Microbiology (1995) 1.26
Plasmid-determined antibiotic synthesis and resistance in Streptomyces coelicolor. Nature (1975) 1.25
The Rhizobium--legume symbiosis. Proc R Soc Lond B Biol Sci (1979) 1.25
Transcriptional organization and regulation of an antibiotic export complex in the producing Streptomyces culture. Mol Gen Genet (1991) 1.24
Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant. J Bacteriol (1995) 1.23
Structural and functional analysis of the mini-circle, a transposable element of Streptomyces coelicolor A3(2). Mol Microbiol (1989) 1.23
"Strong incompatibility" between derivatives of the Streptomyces multi-copy plasmid pIJ101. Mol Gen Genet (1988) 1.21
Molecular cloning and expression of the phenoxazinone synthase gene from Streptomyces antibioticus. J Biol Chem (1984) 1.20
Identification of a flavin:NADH oxidoreductase involved in the biosynthesis of actinorhodin. Purification and characterization of the recombinant enzyme. J Biol Chem (1995) 1.20
Characterisation of actI-homologous DNA encoding polyketide synthase genes from the monensin producer Streptomyces cinnamonensis. Mol Gen Genet (1992) 1.20
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22: sequence analysis and expression in a heterologous host. Chem Biol (1998) 1.20
Engineered biosynthesis of novel polyketides: evidence for temporal, but not regiospecific, control of cyclization of an aromatic polyketide precursor. Chem Biol (1994) 1.19
Biosynthesis of the antibiotic actinorhodin. Analysis of blocked mutants of Streptomyces coelicolor. J Antibiot (Tokyo) (1987) 1.18
A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp. J Bacteriol (1992) 1.18
A new kind of fertility variant in Streptomyces coelicolor. Genetics (1969) 1.16
Functional replacement of genes for individual polyketide synthase components in Streptomyces coelicolor A3(2) by heterologous genes from a different polyketide pathway. J Bacteriol (1992) 1.16
A plasmid of Streptomyces coelicolor carrying a chromosomal locus and its inter-specific transfer. J Gen Microbiol (1973) 1.14
Relationships between fatty acid and polyketide synthases from Streptomyces coelicolor A3(2): characterization of the fatty acid synthase acyl carrier protein. J Bacteriol (1996) 1.13
Beta-ketoacyl acyl carrier protein synthase III (FabH) is essential for fatty acid biosynthesis in Streptomyces coelicolor A3(2). J Bacteriol (2001) 1.13
Extrachromosomally determined antibiotic production. Annu Rev Microbiol (1978) 1.12
CDA is a new chromosomally-determined antibiotic from Streptomyces coelicolor A3(2). J Gen Microbiol (1983) 1.12
Properties of in vitro recombinant derivatives of pJV1, a multi-copy plasmid from Streptomyces phaeochromogenes. J Gen Microbiol (1986) 1.11
A 2.6 kb DNA sequence of Streptomyces coelicolor A3(2) which functions as a transposable element. Mol Gen Genet (1986) 1.10
Genetic control of fertility in Streptomyces coelicolor A3(2): the IF fertility type. J Gen Microbiol (1970) 1.09
Polyketide synthase acyl carrier proteins from Streptomyces: expression in Escherichia coli, purification and partial characterisation. Biochim Biophys Acta (1995) 1.09
Cloning of large DNA fragments, which hybridize with actinorhodin biosynthesis genes, from kalafungin and nanaomycin A methyl ester producers and identification of genes for kalafungin biosynthesis of the kalafungin producer. J Antibiot (Tokyo) (1991) 1.09
Chloramphenicol acetylation in Streptomyces. J Gen Microbiol (1976) 1.08
Expression of a Streptomyces plasmid promoter in Escherichia coli. Gene (1986) 1.07
Nucleotide sequence of the chloramphenicol acetyltransferase gene of Streptomyces acrimycini. Gene (1989) 1.06
Production of new hybrid antibiotics, mederrhodins A and B, by a genetically engineered strain. Antimicrob Agents Chemother (1986) 1.06
Structure, function and engineering of Bacillus thuringiensis toxins. Genet Eng (N Y) (1995) 1.05
Factors affecting recombinant frequency in protoplast fusions of Streptomyces coelicolor. J Gen Microbiol (1979) 1.04