Published in Thromb Res Suppl on January 01, 1983
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The Burlington randomized trial of the nurse practitioner. N Engl J Med (1974) 17.02
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Increased absenteeism from work after detection and labeling of hypertensive patients. N Engl J Med (1978) 9.29
The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure. Can Med Assoc J (1985) 8.06
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Controversy in counting and attributing events in clinical trials. N Engl J Med (1979) 7.25
Randomised clinical trial of strategies for improving medication compliance in primary hypertension. Lancet (1975) 7.22
Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med (1995) 6.86
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Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers. Proc Natl Acad Sci U S A (1996) 5.51
Users' guides to the medical literature. IX. A method for grading health care recommendations. Evidence-Based Medicine Working Group. JAMA (1995) 5.28
Problems in the handling of clinical and research evidence by medical practitioners. Arch Intern Med (1983) 5.16
A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism. N Engl J Med (1999) 5.14
A randomized trial of continuing medical education. N Engl J Med (1982) 4.95
Improvement of medication compliance in uncontrolled hypertension. Lancet (1976) 4.84
Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost (2000) 4.81
A comparison of low-molecular-weight heparin administered primarily at home with unfractionated heparin administered in the hospital for proximal deep-vein thrombosis. N Engl J Med (1996) 4.70
Determining optimal therapy--randomized trials in individual patients. N Engl J Med (1986) 4.49
Effect of encouragement on walking test performance. Thorax (1984) 4.44
The Burlington randomized trial of the nurse practitioner: health outcomes of patients. Ann Intern Med (1974) 4.37
Canadian implantable defibrillator study (CIDS) : a randomized trial of the implantable cardioverter defibrillator against amiodarone. Circulation (2000) 4.12
Subcutaneous fondaparinux versus intravenous unfractionated heparin in the initial treatment of pulmonary embolism. N Engl J Med (2003) 3.94
A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement. N Engl J Med (1993) 3.67
The utility of different health states as perceived by the general public. J Chronic Dis (1978) 3.65
Double-blind randomised trial of a very-low-dose warfarin for prevention of thromboembolism in stage IV breast cancer. Lancet (1994) 3.51
Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes. J Cell Biol (1986) 3.51
Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomised controlled trial. Lancet (2000) 3.50
An empirical demonstration of Berkson's bias. J Chronic Dis (1978) 3.48
Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset. Science (1984) 3.47
Effect of bromhexine on ventilatory capacity in patients with a variety of chest diseases. Lancet (1969) 3.34
Effects of physiologic pacing versus ventricular pacing on the risk of stroke and death due to cardiovascular causes. Canadian Trial of Physiologic Pacing Investigators. N Engl J Med (2000) 3.32
The North American Symptomatic Carotid Endarterectomy Trial : surgical results in 1415 patients. Stroke (1999) 3.31
Can simple clinical measurements detect patient noncompliance? Hypertension (1981) 3.29
Diagnosis and treatment of chronic arterial insufficiency of the lower extremities: a critical review. Circulation (1996) 3.23
Different intensities of oral anticoagulant therapy in the treatment of proximal-vein thrombosis. N Engl J Med (1982) 3.16
Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest (1986) 3.16
p53 is associated with cellular microtubules and is transported to the nucleus by dynein. Nat Cell Biol (2000) 3.05
Does a mailed continuing education program improve physician performance? Results of a randomized trial in antihypertensive care. JAMA (1986) 3.04
A randomized trial of a family physician intervention for smoking cessation. JAMA (1988) 3.03
Choosing the best research design for each question. BMJ (1998) 3.03
Continuous intravenous heparin compared with intermittent subcutaneous heparin in the initial treatment of proximal-vein thrombosis. N Engl J Med (1986) 3.00
Aspirin, sulfinpyrazone, or both in unstable angina. Results of a Canadian multicenter trial. N Engl J Med (1985) 2.99
The measurement iterative loop: a framework for the critical appraisal of need, benefits and costs of health interventions. J Chronic Dis (1985) 2.96
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Warfarin sodium versus low-dose heparin in the long-term treatment of venous thrombosis. N Engl J Med (1979) 2.91
Do the facts and figures warrant a 10-fold increase in the performance of carotid endarterectomy on asymptomatic patients? Neurology (1996) 2.89
Significance testing to establish equivalence between treatments, with special reference to data in the form of 2X2 tables. Biometrics (1977) 2.87
Quality-of-care appraisal in primary care: a quantitative method. Ann Intern Med (1975) 2.87
Rules of evidence and clinical recommendations on the use of antithrombotic agents. Chest (1992) 2.81
Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations. Genes Chromosomes Cancer (2000) 2.73
Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam Consultation on Meta-Analysis. J Clin Epidemiol (1995) 2.73
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Prognostic importance of myocardial ischemia detected by ambulatory monitoring early after acute myocardial infarction. N Engl J Med (1996) 2.69
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Clinical recommendations using levels of evidence for antithrombotic agents. Chest (1995) 2.52
Identification of Plasmodium falciparum histidine-rich protein 2 in the plasma of humans with malaria. J Clin Microbiol (1991) 2.49
Use of a clinical model for safe management of patients with suspected pulmonary embolism. Ann Intern Med (1998) 2.49
Comparative analysis of the Plasmodium falciparum histidine-rich proteins HRP-I, HRP-II and HRP-III in malaria parasites of diverse origin. Parasitology (1987) 2.45
The North American Vasovagal Pacemaker Study (VPS). A randomized trial of permanent cardiac pacing for the prevention of vasovagal syncope. J Am Coll Cardiol (1999) 2.44
Randomised comparison of two intensities of oral anticoagulant therapy after tissue heart valve replacement. Lancet (1988) 2.44
Using research findings in clinical practice. BMJ (1998) 2.40
The rational clinical examination. Does this patient have a clinically important carotid bruit? JAMA (1993) 2.38
The rational clinical examination. Does this patient have splenomegaly? JAMA (1993) 2.38
Hypertension in a family practice. Can Med Assoc J (1977) 2.36
Incidence of recurrent thromboembolic and bleeding complications among patients with venous thromboembolism in relation to both malignancy and achieved international normalized ratio: a retrospective analysis. J Clin Oncol (2000) 2.35
Ultrasonographic screening before hospital discharge for deep venous thrombosis after arthroplasty: the post-arthroplasty screening study. A randomized, controlled trial. Ann Intern Med (1997) 2.28