Relationships among Ara-CTP pools, formation of (Ara-C)DNA, and cytotoxicity of human leukemic cells.

PubWeight™: 0.93‹?›

🔗 View Article (PMID 6587917)

Published in Blood on July 01, 1984

Authors

D Kufe, D Spriggs, E M Egan, D Munroe

Articles by these authors

Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma (1984) 3.74

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature (1999) 3.55

Interaction between ATM protein and c-Abl in response to DNA damage. Nature (1997) 2.70

RNA in human leukemic cells related to the RNA of a mouse leukemia virus (leukocytes-RNA-DNA hybridization-rauscher virus-polysomal RNA). Proc Natl Acad Sci U S A (1972) 2.55

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage. J Biol Chem (2000) 2.44

Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis. J Exp Med (1996) 2.42

The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin. J Biol Chem (2001) 2.37

Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion. J Biol Chem (1997) 2.32

Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells. Nat Med (1997) 2.31

Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin. Mol Cell Biol (1998) 2.29

Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes. J Clin Invest (1988) 2.29

Compliance with zidovudine therapy in patients infected with human immunodeficiency virus, type 1: a cross-sectional study in a municipal hospital clinic. Am J Med (1992) 2.25

Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial. IMPACT-AMI Investigators. Circulation (1997) 2.23

The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin. J Biol Chem (2001) 2.19

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90. EMBO J (2000) 2.13

Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. J Clin Invest (1991) 2.08

Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen. Proc Natl Acad Sci U S A (1988) 2.08

Medical service redesign shares the load saving 6000 bed days and improving morale. Intern Med J (2014) 2.00

Human sarcomas contain RNA related to the RNA of a mouse leukemia virus. Science (1972) 1.98

Viral-related RNA in Hodgkins' disease and other human lymphomas. Proc Natl Acad Sci U S A (1972) 1.98

Expression of the c-fms proto-oncogene during human monocytic differentiation. Nature (1985) 1.88

Prescribing patterns of nurse practitioners. Am J Nurs (1982) 1.82

Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis. Proc Natl Acad Sci U S A (1997) 1.82

MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90. Oncogene (2006) 1.75

Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene (2000) 1.72

Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation. Mol Cell Biol (1987) 1.69

Phase I trial of 3-hour infusion of paclitaxel with or without granulocyte colony-stimulating factor in patients with advanced cancer. J Clin Oncol (1994) 1.67

Preventive antitumor activity against hepatocellular carcinoma (HCC) induced by immunization with fusions of dendritic cells and HCC cells in mice. J Gastroenterol (2001) 1.62

Correlation of cytotoxicity with incorporation of ara-C into DNA. J Biol Chem (1980) 1.58

Immunohistochemical detection and significance of axillary lymph node micrometastases in breast carcinoma. A study of 97 cases. Anal Quant Cytol Histol (1993) 1.58

The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism. Mol Pharmacol (2001) 1.55

Functional interaction between DNA-PK and c-Abl in response to DNA damage. Nature (1997) 1.54

Regulation of Rad51 function by c-Abl in response to DNA damage. J Biol Chem (1998) 1.53

Expression of tumor necrosis factor receptors on human monocytes and internalization of receptor bound ligand. J Immunol (1987) 1.49

Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis. J Biol Chem (2000) 1.48

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci U S A (1997) 1.48

Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: a phase II clinical trial with a differentiation-inducing agent. Blood (1992) 1.46

Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species. J Biol Chem (2000) 1.45

Burkitt's tumors contain particles encapsulating RNA-instructed DNA polymerase and high molecular weight virus-related RNA. Proc Natl Acad Sci U S A (1973) 1.44

Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress. J Biol Chem (2000) 1.43

Role for p300 in stabilization of p53 in the response to DNA damage. J Biol Chem (1999) 1.43

Prognosis of patients treated with whole-brain radiation therapy for metastatic gestational trophoblastic disease. Gynecol Oncol (1998) 1.42

Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis. Mol Cell Biol (1998) 1.40

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage. Nature (1996) 1.39

Utility of medical ethics. Intern Med J (2003) 1.38

Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein. Cancer Res (1995) 1.37

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN. Proc Natl Acad Sci U S A (1991) 1.36

Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line. Proc Natl Acad Sci U S A (1987) 1.34

Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced apoptosis. Mol Cell Biol (2001) 1.33

Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene (1998) 1.32

Targeting of protein kinase C delta to mitochondria in the oxidative stress response. Cell Growth Differ (2001) 1.31

Enteroendocrine localization of GLP-2 receptor expression in humans and rodents. Gastroenterology (2000) 1.31

Overexpression of Bcl-XL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation. Cell Growth Differ (1995) 1.30

Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells. Proc Natl Acad Sci U S A (1998) 1.29

Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit. J Biol Chem (1997) 1.29

Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone. Genomics (1997) 1.28

Fusions of human ovarian carcinoma cells with autologous or allogeneic dendritic cells induce antitumor immunity. J Immunol (2000) 1.28

Activation of antitumor cytotoxic T lymphocytes by fusions of human dendritic cells and breast carcinoma cells. Proc Natl Acad Sci U S A (2000) 1.26

Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms. J Biol Chem (1996) 1.26

Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor. Blood (1987) 1.26

Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation. Oncogene (1998) 1.26

Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer. Oncogene (2009) 1.24

Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance. J Biol Chem (1998) 1.24

RNA related to that of a murine leukemia virus in Burkitt's tumors and nasopharyngeal carcinomas. Proc Natl Acad Sci U S A (1973) 1.23

XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage. J Biol Chem (2000) 1.22

Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine. Blood (1996) 1.22

Targeting of the c-Abl tyrosine kinase to mitochondria in the necrotic cell death response to oxidative stress. J Biol Chem (2001) 1.21

Lethality of human myeloblasts correlates with the incorporation of arabinofuranosylcytosine into DNA. Proc Natl Acad Sci U S A (1981) 1.20

A comparative study of the biologic and molecular basis of murine mammary carcinoma: a model for human breast cancer. J Natl Cancer Inst (1973) 1.19

c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine. J Biol Chem (1995) 1.19

Evidence for RNA tumor viruses in human lymphomas including Burkitt's disease. Cancer Res (1973) 1.19

Human granulocyte-macrophage colony-stimulating factor induces expression of the tumor necrosis factor gene by the U937 cell line and by normal human monocytes. J Clin Invest (1987) 1.18

Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation. J Clin Invest (1991) 1.18

Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells. J Biol Chem (1997) 1.16

Proteolytic cleavage and activation of protein kinase C [micro] by caspase-3 in the apoptotic response of cells to 1-beta -D-arabinofuranosylcytosine and other genotoxic agents. J Biol Chem (2000) 1.16

Colony-stimulating factor 1 activates protein kinase C in human monocytes. EMBO J (1990) 1.16

Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation. EMBO J (2000) 1.16

Posttranscriptional stabilization of c-fms mRNA by a labile protein during human monocytic differentiation. Mol Cell Biol (1989) 1.16

Type-specific antigenic determinants on the major external glycoprotein of high- and low-oncogenic murine mammary tumor viruses. J Virol (1977) 1.16

Immunization of ovarian cancer patients with a synthetic Lewis(y)-protein conjugate vaccine: a phase 1 trial. Int J Cancer (2000) 1.15

Transcriptional and posttranscriptional control of c-fos gene expression in human monocytes. Mol Cell Biol (1988) 1.15

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase. Curr Biol (2000) 1.14

Radiolocalization of human mammary tumors in athymic mice by a monoclonal antibody. Cancer Res (1983) 1.13

Characterization of cis-acting elements regulating transcription of the human DF3 breast carcinoma-associated antigen (MUC1) gene. Proc Natl Acad Sci U S A (1993) 1.13

Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis. J Biol Chem (1997) 1.12

Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage. Mol Cell Biol (1999) 1.12

Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation. J Biol Chem (1994) 1.11

Expression of the macrophage specific colony-stimulating factor (CSF-1) during human monocytic differentiation. Biochem Biophys Res Commun (1986) 1.10

Effect of tumor necrosis factor on GTP binding and GTPase activity in HL-60 and L929 cells. J Biol Chem (1988) 1.10

Multiple antigenic determinants on the major surface glycoprotein of murine mammary tumor viruses. Proc Natl Acad Sci U S A (1977) 1.10

Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage. Mol Cell Biol (2000) 1.09

The novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism. Cell Growth Differ (2000) 1.09

A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs). Cell Biochem Biophys (1999) 1.08

Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation. Proc Natl Acad Sci U S A (1986) 1.08

Phase I and pharmacologic study of paclitaxel administered weekly in patients with relapsed ovarian cancer. J Clin Oncol (1997) 1.07

Macrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2. EMBO J (1992) 1.06

Expression of the macrophage colony-stimulating factor and c-fms genes in human acute myeloblastic leukemia cells. J Clin Invest (1988) 1.05

Lateralized and widespread brain activation during transient blood pressure elevation revealed by magnetic resonance imaging. J Comp Neurol (2000) 1.05