R A Somerville

Author PubWeight™ 34.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Abnormal fibrils from scrapie-infected brain. Acta Neuropathol 1981 5.35
2 Infection-specific particle from the unconventional slow virus diseases. Science 1984 2.34
3 Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques. Acta Neuropathol 1983 2.23
4 Scrapie-associated fibrils in Creutzfeldt-Jakob disease. Nature 1984 2.11
5 Biochemical typing of scrapie strains. Nature 1997 1.59
6 Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy. J Virol Methods 1989 1.38
7 Partial copurification of scrapie-associated fibrils and scrapie infectivity. Intervirology 1986 1.10
8 Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie. J Gen Virol 1994 0.99
9 Altered scrapie infectivity estimates by titration and incubation period in the presence of detergents. J Gen Virol 1983 0.99
10 Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice. J Gen Virol 1992 0.93
11 Straining the prion hypothesis. Nature 1998 0.91
12 Scrapie associated fibrils in the diagnosis of scrapie in sheep. Vet Rec 1987 0.89
13 Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy. J Gen Virol 1996 0.87
14 Immunodetection of a disease specific PrP fraction in scrapie-affected sheep and BSE-affected cattle. Vet Rec 1992 0.87
15 Ultrastructural links between scrapie and Alzheimer's disease. Lancet 1985 0.83
16 Sensitivity of scrapie infectivity to detergents and 2-mercaptoethanol. Intervirology 1980 0.83
17 Distribution of a bovine spongiform encephalopathy-derived agent over ion-exchange chromatography used in the preparation of concentrates of fibrinogen and factor VIII. Vox Sang 2004 0.81
18 Ubiquitin conjugate immunoreactivity in the brains of scrapie infected mice. J Pathol 1990 0.81
19 Bovine spongiform encephalopathy in sheep? Rev Sci Tech 2003 0.80
20 Changes in a protein-nucleic acid complex from synaptic plasma membrane of scrapie-infected mouse brain. Biochem Soc Trans 1976 0.79
21 Prion protein: detection in 'spiked' anaerobic sludge and degradation experiments under anaerobic conditions. Water Sci Technol 2006 0.79
22 Inactivation of the BSE agent by the heat and pressure process for manufacturing gelatine. Vet Rec 2005 0.79
23 Is there more to TSE diseases than PrP? Trends Microbiol 2000 0.79
24 Studies on the removal of a bovine spongiform encephalopathy-derived agent by processes used in the manufacture of human immunoglobulin. Vox Sang 2002 0.78
25 Decreased high-affinity binding of [3H]muscimol to cerebral synaptic membranes of scrapie-infected mice. J Neurochem 1984 0.77
26 Relative efficiency of transmitting bovine spongiform encephalopathy to RIII mice by the oral route. Vet Rec 2001 0.77
27 Infectivity in the blood of mice with a BSE-derived agent. J Hosp Infect 2000 0.76
28 Limited efficacy of steam sterilization to inactivate vCJD infectivity. J Hosp Infect 2011 0.76
29 Brain glutamate decarboxylase and cholinergic enzyme activities in scrapie. J Neurol Sci 1985 0.76
30 The effects of detergents on the composition of postsynaptic densities. J Neurochem 1984 0.75
31 Prions. A challenge to Science, Medicine and the Public Health System. Br J Biomed Sci 2004 0.75
32 Risk of escape of prions in gaseous emissions from on-farm digestion vessels. Vet Rec 2010 0.75
33 Nucleic acids associated with detergent-treated synaptosomal plasma membranes from normal and scrapie-infected mouse brain. Biochem Soc Trans 1976 0.75
34 Inactivation of BSE infectivity on chips of bone by autoclaving during the manufacture of gelatine. Vet Rec 2006 0.75
35 Inactivation of transmissible spongiform encephalopathy agents during the manufacture of dicalcium phosphate from bone. Vet Rec 2006 0.75