Published in Cancer Res on June 01, 1977
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy. Clin Cancer Res (2013) 2.00
Pharmacokinetic and pharmacodynamic analysis of 5-aza-2'-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy. Clin Epigenetics (2013) 1.30
Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposon. PLoS Genet (2006) 1.28
CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors. Leukemia (2011) 1.25
p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia. Leukemia (2011) 1.09
A phase I trial of cisplatin plus decitabine, a new DNA-hypomethylating agent, in patients with advanced solid tumors and a follow-up early phase II evaluation in patients with inoperable non-small cell lung cancer. Invest New Drugs (2000) 1.07
Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine. Blood (2011) 1.02
p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies. Semin Oncol (2012) 0.97
Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia. Br J Cancer (1988) 0.92
High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects. Oncotarget (2012) 0.89
A pilot study of subcutaneous decitabine in β-thalassemia intermedia. Blood (2011) 0.88
Pharmacokinetics and Pharmacodynamics with Extended Dosing of CC-486 in Patients with Hematologic Malignancies. PLoS One (2015) 0.77
Ex vivo expansion of human mobilized peripheral blood stem cells using epigenetic modifiers. Transfusion (2014) 0.76
Efficacy and safety of extended dosing schedules of CC-486 (oral azacitidine) in patients with lower-risk myelodysplastic syndromes. Leukemia (2015) 0.75
Subchronic oral toxicity study of decitabine in combination with tetrahydrouridine in CD-1 mice. Int J Toxicol (2014) 0.75
Mycobacterium tuberculosis invades and replicates within type II alveolar cells. Infect Immun (1996) 3.11
Training impulsive children to talk to themselves: a means of developing self-control. J Abnorm Psychol (1971) 3.08
A randomized, double-blind comparative trial evaluating the safety of liposomal amphotericin B versus amphotericin B lipid complex in the empirical treatment of febrile neutropenia. L Amph/ABLC Collaborative Study Group. Clin Infect Dis (2000) 2.63
Functional-anatomic correlates of object priming in humans revealed by rapid presentation event-related fMRI. Neuron (1998) 2.61
The developmental control of operant motor responding by verbal operants. J Exp Child Psychol (1969) 2.45
Partial purification and properties of two forms of deoxyribonucleic acid polymerase from calf thymus. J Biol Chem (1973) 2.31
Effect of cytosine arabinoside 5'-triphosphate on mammalian DNA polymerase. Biochem Biophys Res Commun (1969) 2.16
CAPILLARY PERMEABILITY IN RELATION TO ACUTE ANOXIA AND TO VENOUS OXYGEN SATURATION. J Clin Invest (1947) 2.03
Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells. Cancer Res (1976) 1.70
Cryptococcal disease presenting as cellulitis. Clin Infect Dis (1992) 1.63
Reducing tobacco consumption in California: Proposition 99 seems to work. JAMA (1991) 1.55
A model for the chemotherapy of acute leukemia with 1-beta-D-arabinofuranosylcytosine. Cancer Res (1974) 1.48
Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin. Biochem Biophys Res Commun (1977) 1.40
Measuring variability in early child language: don't shoot the messenger. Child Dev (2000) 1.39
Incorporation of 5-Aza-2'-deoxycytidine-5'-triphosphate into DNA. Interactions with mammalian DNA polymerase alpha and DNA methylase. Mol Pharmacol (1983) 1.37
Striatal volume loss in HD as measured by MRI and the influence of CAG repeat. Neurology (2001) 1.33
THE EFFECTS OF CONTINUOUS PRESSURE BREATHING ON KIDNEY FUNCTION. J Clin Invest (1947) 1.30
Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside. Biochem Pharmacol (1983) 1.24
Inhibition of DNA methylation in L1210 leukemic cells by 5-aza-2'-deoxycytidine as a possible mechanism of chemotherapeutic action. Cancer Res (1983) 1.19
Exposure to low oxygen tension and increased osmolarity enhance the ability of Mycobacterium avium to enter intestinal epithelial (HT-29) cells. Infect Immun (1997) 1.17
Granulocytosis associated with tumor cell production of colony-stimulating activity. Blood (1983) 1.16
Kinetic studies on 2',2'-difluorodeoxycytidine (Gemcitabine) with purified human deoxycytidine kinase and cytidine deaminase. Biochem Pharmacol (1993) 1.15
Phase I study on 5-aza-2'-deoxycytidine in children with acute leukemia. Leuk Res (1981) 1.15
Interaction of Mycobacterium avium with human monocyte-derived dendritic cells. Infect Immun (2000) 1.10
Reflection-impulsivity and verbal control of motor behavior. Child Dev (1969) 1.10
Molecular, cellular and animal pharmacology of 5-aza-2'-deoxycytidine. Pharmacol Ther (1985) 1.08
fMRI of sensitization to angry faces. Neuroimage (2005) 1.07
Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase. Cancer Chemother Pharmacol (1992) 1.07
Clinical trial on 5-aza-2'-deoxycytidine in patients with acute leukemia. Pharmacol Ther (1985) 1.07
Mammalian deoxynucleoside kinase. I. Deoxycytidine kinase: purification, properties, and kinetic studies with cytosine arabinoside. J Biol Chem (1968) 1.06
Polyethylene intrauterine contraceptive device. Endometrial changes following long-term use. JAMA (1970) 1.06
Cognitive deficits in a genetic mouse model of the most common biochemical cause of human mental retardation. J Neurosci (1999) 1.05
Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Ann Intern Med (1984) 1.04
Comparison of the antileukemic activity of 5-AZA-2'-deoxycytidine, 1-beta-D-arabinofuranosylcytosine and 5-azacytidine against L1210 leukemia. Leuk Res (1984) 1.04
Mycobacterium avium invades the intestinal mucosa primarily by interacting with enterocytes. Infect Immun (2001) 1.04
Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells. Cancer Chemother Pharmacol (2001) 1.03
Plasma and cerebrospinal fluid pharmacokinetics of 5-Aza-2'-deoxycytidine in rabbits and dogs. Cancer Res (1983) 1.03
Kinetic and template studies with 1- -D-arabinofuranosylcytosine 5'-triphosphate and mammalian deoxyribonucleic acid polymerase. Mol Pharmacol (1972) 1.03
Mycobacterium avium enters intestinal epithelial cells through the apical membrane, but not by the basolateral surface, activates small GTPase Rho and, once within epithelial cells, expresses an invasive phenotype. Cell Microbiol (2000) 1.02
DNA methylation of retinoic acid receptor beta in breast cancer and possible therapeutic role of 5-aza-2'-deoxycytidine. Anticancer Drugs (1999) 1.01
Studies on a new mechanism of resistance of L5178Y murine leukemia cells to cytosine arabinoside. Biochim Biophys Acta (1968) 1.01
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells. Anticancer Drugs (1998) 1.00
Mammalian deoxynucleoside kinases. II. Deoxyadenosine kinase: purification and properties. J Biol Chem (1971) 0.99
Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2'-deoxycytidine. Leuk Res (1985) 0.97
Kinetics of phosphorylation of 5-aza-2'-deoxyycytidine by deoxycytidine kinase. Biochem Pharmacol (1979) 0.97
Long-term survival in rhinocerebral mucormycosis. Case report. J Neurosurg (1998) 0.96
Studies on the biochemistry of mitochondria and cell morphology in the neonatal swine hepatocyte. J Cell Biol (1972) 0.96
Role of complement receptors in uptake of Mycobacterium avium by macrophages in vivo: evidence from studies using CD18-deficient mice. Infect Immun (1999) 0.95
Cell cycle effects and cellular pharmacology of 5-aza-2'-deoxycytidine. Cancer Chemother Pharmacol (1984) 0.95
Lung-sparing surgery after penetrating trauma using tractotomy, partial lobectomy, and pneumonorrhaphy. Arch Surg (1999) 0.95
High-performance liquid chromatographic analysis of chemical stability of 5-aza-2'-deoxycytidine. J Pharm Sci (1981) 0.94
Pulmonary rapidly adapting receptors reflexly increase airway secretion in dogs. J Appl Physiol (1985) (1989) 0.93
Expression of voltage-gated calcium channel subunits in rat dorsal root ganglion neurons. Neurosci Lett (2001) 0.93
Drug resistance to 5-aza-2'-deoxycytidine, 2',2'-difluorodeoxycytidine, and cytosine arabinoside conferred by retroviral-mediated transfer of human cytidine deaminase cDNA into murine cells. Cancer Chemother Pharmacol (1998) 0.93
Homing markers for atherosclerosis: applications for drug delivery, gene delivery and vascular imaging. FEBS Lett (2001) 0.93
Cross-validation of the Delirium Rating Scale in older patients. J Am Geriatr Soc (1996) 0.92
LL-E19085 alpha, a novel antibiotic from Micromonospora citrea: taxonomy, fermentation and biological activity. J Antibiot (Tokyo) (1989) 0.92
Alteration in membrane protein band 3 associated with accelerated erythrocyte aging. Proc Natl Acad Sci U S A (1989) 0.90
Human cytidine deaminase: purification of enzyme, cloning, and expression of its complementary DNA. Cancer Res (1994) 0.90
Mesenchymal-epithelial interactions in the bladder. World J Urol (1996) 0.90
High rate of maternal vitamin B12 deficiency nearly a decade after Canadian folic acid flour fortification. QJM (2008) 0.88
Simaomicin (LL-D42067), a novel antibiotic from Actinomadura madurae. I. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo) (1990) 0.87
Studies on the origin of amniotic fluid lipids. I. Normal composition. Am J Obstet Gynecol (1968) 0.87
Overregularization in English plural and past tense inflectional morphology: a response to Marcus (1995). J Child Lang (1997) 0.87
Activation of the retinoic acid receptor beta gene by 5-aza-2'-deoxycytidine in human DLD-1 colon carcinoma cells. Anticancer Drugs (1997) 0.86
Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent. J Med Chem (1989) 0.85
Selection against small males in utero: a test of the Wells hypothesis. Hum Reprod (2012) 0.85
Kinetic studies on phosphorylation of 5-azacytidine with the purified uridine-cytidine kinase from calf thymus. Cancer Res (1974) 0.85
Multiple pancreatic pseudocyst disease. Ann Surg (1984) 0.85
Hapten-sandwich labeling. I. A general procedure for simultaneous labeling of multiple cell surface antigens for fluorescence and electron microscopy. J Exp Med (1974) 0.85
Caesarean splenectomy for spontaneous rupture of splenic artery aneurysm at 34 weeks gestation with survival of the mother and the preterm fetus. J Obstet Gynaecol (2006) 0.84
Eye tracking disorder in schizophrenia is characterized by specific ocular motor defects and is associated with the deficit syndrome. Biol Psychiatry (1997) 0.84
Sample preparation for the determination of 5-aza-2'-deoxycytidine in plasma by high-performance liquid chromatography. J Chromatogr (1985) 0.83
Studies on the phosphorylation of cytosine arabinoside in mammalian cells. Mol Pharmacol (1971) 0.83
Effects of 5-aza-2'-deoxycytidine on survival and cell cycle progression of L1210 leukemia cells. Leuk Res (1986) 0.83
Antileukemic activity of 5-aza-2'-deoxycytidine and cytarabine against intracerebral L1210 murine leukemia. Cancer Treat Rep (1984) 0.83
Practice patterns in the diagnosis and treatment of erectile dysfunction among family practice physicians. Urology (2001) 0.83
Esophageal and duodenal atresia in a fetus with Down's syndrome: prenatal sonographic features. Ultrasound Obstet Gynecol (1996) 0.83
Reye's syndrome in twins. J Pediatr (1970) 0.82
Effect of DNA polymerase on nuclei from different phases of cell cycle. Eur J Biochem (1974) 0.82
Dexamethasone in the treatment of obstetric cholestasis: a case series. J Obstet Gynaecol (2006) 0.81
Membrane channel protein abnormalities and autoantibodies in neurological disease. Brain Res Bull (1990) 0.81
Comparison of the induction of apoptosis in human leukemic cell lines by 2',2'-difluorodeoxycytidine (gemcitabine) and cytosine arabinoside. Leuk Res (1995) 0.81
Mammalian deoxynucleoside kinases. IV. Deoxythymidine kinase: purification, properties, and kinetic studies. J Biol Chem (1971) 0.81
Membrane protein band 3 alteration associated with neurologic disease and tissue-reactive antibodies. Exp Clin Immunogenet (1990) 0.81
Autoantibodies to band 3 during aging and disease and aging interventions. Ann N Y Acad Sci (1994) 0.81
Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene. Cancer Gene Ther (2001) 0.81
Presurgical serum albumin levels predict survival time from glioblastoma multiforme. J Neurooncol (1999) 0.81
Mammalian deoxynucleoside kinases. 3. Deoxyadenosine kinase: inhibition by nucleotides and kinetic studies. J Biol Chem (1971) 0.81
Comparison of antineoplastic activity of 2',2'-difluorodeoxycytidine and cytosine arabinoside against human myeloid and lymphoid leukemic cells. Anticancer Drugs (1991) 0.80
Toxicology in mice of the antileukemic agent 5-aza-2'-deoxycytidine. Drug Chem Toxicol (1981) 0.80
Risk factors in local surgical procedures for diabetic gangrene. Surg Gynecol Obstet (1976) 0.80
5-aza-2'-deoxycytidine therapy in patients with acute leukemia inhibits DNA methylation. Leuk Res (1984) 0.80
Environment and waiting behaviors in emergency waiting areas. Child Health Care (1985) 0.80
Inelastic demand for alcohol in rats. Psychopharmacology (Berl) (1999) 0.80
Interaction of retinoic acid and vitamin D3 analogs on HL-60 myeloid leukemic cells. Leuk Res (1993) 0.80
Streptozocin-induced neuropathy is associated with altered expression of voltage-gated calcium channel subunit mRNAs in rat dorsal root ganglion neurones. Biochem Biophys Res Commun (2001) 0.80
Cleavage of intracellular hepatitis C RNA in the virus core protein coding region by deoxyribozymes. J Viral Hepat (2006) 0.80
Creatine ingestion increases anaerobic capacity and maximum accumulated oxygen deficit. Can J Appl Physiol (1997) 0.80
Effect of nortestosterone decanoate on red cell 2,3 diphosphoglycerate and hematocrit in hemodialysis patients. Clin Pharmacol Ther (1975) 0.80