Inhibition of thromboxane A2 biosynthesis in human platelets by burimamide.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 2044402)

Published in Br J Pharmacol on January 01, 1980

Authors

G Allan, K E Eakins, P S Kulkarni, R Levi

Articles cited by this

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol (1971) 37.53

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature (1976) 13.19

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 10.82

Drugs which inhibit prostaglandin biosynthesis. Pharmacol Rev (1974) 7.76

Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. Proc Natl Acad Sci U S A (1973) 4.43

Some chemical aspects of histamine H2-receptor antagonists. Fed Proc (1976) 3.07

Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature (1976) 2.83

Imidazole: a selective inhibitor of thromboxane synthetase. Prostaglandins (1977) 2.48

Synthesis of 6-keto-PGF1alpha by ram seminal vesicle microsomes. Prostaglandins (1977) 1.57

Application of imidazole as a selective inhibitor thromboxane synthetase in human platelets. Proc Natl Acad Sci U S A (1977) 1.56

Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition. Prostaglandins (1976) 1.56

Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes. Biochim Biophys Acta (1978) 1.37

On the inhibitory potency of imidazole and its derivatives on thromboxane synthetase. Biochem Biophys Res Commun (1978) 1.14

The pharmacology of burimamide and metiamide, two histamine H2-receptor antagonists. Fed Proc (1976) 1.07

Selective inhibition of thromboxane A2 biosynthesis in blood platelets. Nature (1977) 0.95

Biosynthesis of thromboxanes in human platelets. I. Characterization and assay of thromboxane synthetase. Biochem Biophys Res Commun (1977) 0.94

The pressor activity of burimamide: a relationship between chemical constitution and pressor activity of burimamide and related histamine H2-receptor antagonists. Agents Actions (1977) 0.89

Burimamide is a selective inhibitor of thromboxane-A biosynthesis in human platelet microsomes. Prostaglandins (1978) 0.84

Selective inhibitory actions of sodium-p-benzyl-4-[1-oxo-2-(4-chlorobenzyl)-3-phenyl propyl] phenyl phosphonate (N-0161) and indomethacin on the biosynthesis of prostaglandins and thromboxanes from arachidonic acid. Br J Pharmacol (1977) 0.78

Microsomal preparations of normal bovine iris-ciliary body generate prostacyclin-like but not thromboxane-A2-activity. Prostaglandins (1977) 0.78

Articles by these authors

Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc Natl Acad Sci U S A (1988) 3.44

NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide. Proc Natl Acad Sci U S A (1990) 3.28

Isolation of circovirus from lesions of pigs with postweaning multisystemic wasting syndrome. Can Vet J (1998) 3.19

NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo? Biochem Biophys Res Commun (1989) 3.11

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide. J Exp Med (1989) 2.99

Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis. Biochem Biophys Res Commun (1990) 2.77

International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol Rev (1997) 2.71

PMWS and porcine dermatitis nephropathy syndrome in Great Britain. Vet Rec (2000) 2.67

Chemokinetic activity of arachidonic and lipoxygenase products on leuocyctes of different species. Prostaglandins (1980) 2.59

Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs. FASEB J (1991) 2.57

Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages. Biochem Biophys Res Commun (1991) 2.26

Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa. Nature (1980) 2.24

EUR-ASSESS Project Subgroup Report on Dissemination and Impact. Int J Technol Assess Health Care (1997) 2.18

The effects of prostaglandins on the intraocular pressure of the rabbit. Br J Pharmacol (1969) 2.12

Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle. J Biol Chem (1992) 2.11

PCV-2 genotype definition and nomenclature. Vet Rec (2008) 2.04

Reproduction of lesions of postweaning multisystemic wasting syndrome in gnotobiotic piglets. J Vet Diagn Invest (1999) 1.98

Release of prostaglandins in ocular inflammation in the rabbit. Nat New Biol (1972) 1.97

Nitric oxide synthase in macula densa regulates glomerular capillary pressure. Proc Natl Acad Sci U S A (1992) 1.93

Viral wasting syndrome of swine: experimental reproduction of postweaning multisystemic wasting syndrome in gnotobiotic swine by coinfection with porcine circovirus 2 and porcine parvovirus. Vet Pathol (2000) 1.82

Quality of life and traumatic spinal cord injury. Arch Phys Med Rehabil (1998) 1.81

Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-and H2-receptor agonists and antagonists. Eur J Pharmacol (1975) 1.80

L-arginine availability determines the duration of acetylcholine-induced systemic vasodilation in vivo. Biochem Biophys Res Commun (1989) 1.76

Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine. Biochem Biophys Res Commun (1990) 1.72

Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome. N Engl J Med (1999) 1.67

Activation of the immune system is the pivotal event in the production of wasting disease in pigs infected with porcine circovirus-2 (PCV-2). Vet Pathol (2001) 1.62

Nitric oxide-stimulated guanine nucleotide exchange on p21ras. J Biol Chem (1995) 1.61

The heart as a target organ in systemic allergic reactions: comparison of cardiac analphylaxis in vivo and in vitro. Circ Res (1975) 1.55

Host cell and EBNA-2 regulation of Epstein-Barr virus latent-cycle promoter activity in B lymphocytes. J Virol (1992) 1.55

Synthesis of nitrogen oxides from L-arginine by macrophage cytosol: requirement for inducible and constitutive components. Biochem Biophys Res Commun (1989) 1.53

Paradoxical endogenous synthesis of a coronary dilating substance from arachidonate. Prostaglandins (1976) 1.52

Antagonism of some smooth muscle actions of prostaglandins by polyphloretin phosphate. Br J Pharmacol (1970) 1.49

Coinfection by porcine circoviruses and porcine parvovirus in pigs with naturally acquired postweaning multisystemic wasting syndrome. J Vet Diagn Invest (2000) 1.48

The effects of non-steroid anti-inflammatory drugs on leukocyte migration in carrageenin-induced inflammation. Eur J Pharmacol (1980) 1.48

Coronary tone modulation: formation and actions of prostaglandins, endoperoxides, and thromboxanes. Science (1977) 1.47

Increased levels of redox-active iron in follicular fluid: a possible cause of free radical-mediated infertility in beta-thalassemia major. Am J Obstet Gynecol (1996) 1.47

Spasticity after traumatic spinal cord injury: nature, severity, and location. Arch Phys Med Rehabil (1999) 1.40

Studies of the effect of recombinant human-alpha 1 interferon on experimental parainfluenza type 3 virus infections of the respiratory tract of calves. Vet Rec (1989) 1.38

Acetyl glyceryl ether phosphorylcholine (AGEPC). A putative mediator of cardiac anaphylaxis in the guinea pig. Circ Res (1984) 1.36

Novel porcine circoviruses from pigs with wasting disease syndromes. Vet Rec (1998) 1.35

Reduction of intraocular pressure by prostaglandins applied topically to the eyes of conscious rabbits. Invest Ophthalmol Vis Sci (1977) 1.32

Reproduction of postweaning multisystemic wasting syndrome (PMWS) in immunostimulated and non-immunostimulated 3-week-old piglets experimentally infected with porcine circovirus type 2 (PCV2). Vet Microbiol (2002) 1.32

Prostaglandin-like activity in ocular inflammation. Br Med J (1972) 1.29

Quantification of ocular inflammation: evaluation of polymorphonuclear leucocyte infiltration by measuring myeloperoxidase activity. Curr Eye Res (1983) 1.29

NG-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. A role for nitric oxide in the central regulation of sympathetic tone? Circ Res (1992) 1.28

Effects of exogenous and immunologically released histamine on the isolated heart: a quantitative comparison. J Pharmacol Exp Ther (1972) 1.27

Leukotrienes C4, D4 and E4: effects on human and guinea-pig cardiac preparations in vitro. J Pharmacol Exp Ther (1982) 1.26

A novel gene encoding a B-box protein within the BRCA1 region at 17q21.1. Hum Mol Genet (1994) 1.25

Nitric oxide in the regulation of blood flow and arterial pressure. Annu Rev Physiol (1995) 1.23

Histamine and cardiac arrhythmias. Circ Res (1986) 1.23

Association of lymphopenia with porcine circovirus type 2 induced postweaning multisystemic wasting syndrome (PMWS). Vet Immunol Immunopathol (2003) 1.23

Inhibition of arachidonic acid cyclo-oxygenase and lipoxygenase activities of leukocytes by indomethacin and compound BW755C. Agents Actions (1980) 1.21

Severe complications of chickenpox in hospitalised children in the UK and Ireland. Arch Dis Child (2007) 1.21

Optical transitions in artificial few-electron atoms strongly confined inside ZnO nanocrystals. Phys Rev Lett (2003) 1.20

Prostaglandin and non-prostaglandin mediated breeakdown of the blood-aqueous barrier. Exp Eye Res (1977) 1.19

Anaphylaxis in the guinea-pig isolated heart: selective inhibition by burimamide of the positive inotropic and chronotropic effects of released histamine. Br J Pharmacol (1973) 1.16

Multiple porcine circovirus 2-associated abortions and reproductive failure in a multisite swine production unit. Can Vet J (2001) 1.15

Channel currents during spontaneous action potentials in embryonic chick heart cells. The action potential patch clamp. Biophys J (1984) 1.15

A universal epitope-based influenza vaccine and its efficacy against H5N1. Vaccine (2009) 1.14

Cardiac histamine receptors. Fed Proc (1976) 1.13

An evaluation of ocular inflammation following the injection of bacterial endotoxin into the rat foot pad. Invest Ophthalmol Vis Sci (1983) 1.10

N-0164 inhibits generation of thromboxane-A2-like activity from prostaglandin endoperoxides by human platelet microsomes. Prostaglandins (1976) 1.09

Mediators of injury in neurotrauma: intracellular signal transduction and gene expression. J Neurotrauma (1995) 1.09

Myeloperoxidase activity as a quantitative marker of polymorphonuclear leukocyte accumulation into an experimental myocardial infarct--the effect of ibuprofen on infarct size and polymorphonuclear leukocyte accumulation. J Cardiovasc Pharmacol (1986) 1.08

Synthetic recombinant vaccine expressing influenza haemagglutinin epitope in Salmonella flagellin leads to partial protection in mice. Vaccine (1992) 1.07

A central nervous system action of nitric oxide in blood pressure regulation. J Pharmacol Exp Ther (1992) 1.07

Bradykinin B2-receptor activation augments norepinephrine exocytosis from cardiac sympathetic nerve endings. Mediation by autocrine/paracrine mechanisms. Circ Res (1997) 1.07

Simultaneous Ashworth measurements and electromyographic recordings in tetraplegic patients. Arch Phys Med Rehabil (1998) 1.06

Inhibition of the prostaglandin synthetase systems in ocular tissues by indomethacin. Br J Pharmacol (1974) 1.06

Pharmacological characterization of cardiac histamine receptors: sensitivity to H1-receptor antagonists. Eur J Pharmacol (1974) 1.06

"The clinical scope of porcine reproductive and respiratory syndrome virus infection has expanded since 1987": an alternative perspective. Vet Pathol (1999) 1.05

PDNS, PMWS and porcine circovirus type 2 in Scotland. Porcine dermatitis and nephropathy syndrome. Post-weaning multisystemic wasting syndrome. Vet Rec (2000) 1.04

Histamine H3-receptor signaling in the heart: possible involvement of Gi/Go proteins and N-type Ca++ channels. J Pharmacol Exp Ther (1994) 1.03

Cardiac dysfunction caused by purified human C3a anaphylatoxin. Proc Natl Acad Sci U S A (1985) 1.03

Prostaglandin antagonism by sodium p-benzyl-4-[1-oxo-2-(4-chlorobenzyl)-3-phenylpropyl]pheenyl phosphonate (N-0164). Br J Pharmacol (1976) 1.02

Antiarrhythmic properties of stereoisomers of a beta-adrenergic blocking agent (H56-28). Anesthesiology (1968) 1.02

Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro. J Pharmacol Exp Ther (1981) 1.01

Heterologous cell-cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1). J Thromb Haemost (2003) 1.01

The effect of steroidal and nonsteroidal anti-inflammatory agents on corneal re-epithelialization. Invest Ophthalmol Vis Sci (1981) 1.00

The arrhythmogenic actions of histamine on human atrial fibers. Circ Res (1981) 1.00

Selective impairment of atrioventricular conduction by 2-(2-pyridyl)-ethylamine and 2-(2-thiazolyl)-ethylamine, two histamine H1-receptor agonists. Eur J Pharmacol (1975) 0.99

Chemotactic response to some arachidonic acid lipoxygenase products in the rabbit eye. Eur J Pharmacol (1981) 0.99

Response of the medial rectus muscle of the cat to succinylcholine. Nature (1965) 0.99

Separation of primary and secondary cardiovascular events in systemic anaphylaxis. Circ Res (1977) 0.99

Modulation of monocytic cell activity and virus susceptibility during differentiation into macrophages. J Immunol (1999) 0.99

The nature of the prostaglandin-blocking activity of polyphloretin phosphate. J Pharmacol Exp Ther (1971) 0.99

Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclooxygenase-derived metabolites. Circ Res (1992) 0.99

Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina. J Am Coll Cardiol (2000) 0.98

Transplacental infection with PCV-2 associated with reproductive failure in a gilt. Vet Rec (2001) 0.98

Activation of histamine H3-receptors inhibits carrier-mediated norepinephrine release during protracted myocardial ischemia. Comparison with adenosine A1-receptors and alpha2-adrenoceptors. Circ Res (1996) 0.98

Prostaglandins and cardiac anaphylaxis. Life Sci (1976) 0.98

Thiamine deficiency in patients with B-chronic lymphocytic leukaemia: a pilot study. Postgrad Med J (2001) 0.97

Unmasking of activated histamine H3-receptors in myocardial ischemia: their role as regulators of exocytotic norepinephrine release. J Pharmacol Exp Ther (1994) 0.97

Increased intraocular pressure produced by prostaglandins E1 and E2 in the cat eye. Exp Eye Res (1970) 0.97

Acute anterior uveitis and prostaglandins. Proc R Soc Med (1973) 0.97