Published in Infect Immun on June 01, 1982
Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family. J Bacteriol (1995) 5.99
Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosa. J Bacteriol (1999) 2.72
Loss of virulence associated with absence of flagellum in an isogenic mutant of Pseudomonas aeruginosa in the burned-mouse model. Infect Immun (1982) 2.48
Role of lipopolysaccharide in virulence of Pseudomonas aeruginosa. Infect Immun (1984) 2.39
Characterization of Pseudomonas cepacia isolates from patients with cystic fibrosis. J Clin Microbiol (1984) 2.23
Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections. Infect Immun (1997) 2.11
Evaluation of Pseudomonas aeruginosa exotoxin A and elastase as virulence factors in acute lung infection. Infect Immun (1983) 2.06
Correlation of elastase production by some strains of Aspergillus fumigatus with ability to cause pulmonary invasive aspergillosis in mice. Infect Immun (1984) 1.97
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Protection against Pseudomonas aeruginosa infection in a murine burn wound sepsis model by passive transfer of antitoxin A, antielastase, and antilipopolysaccharide. Infect Immun (1983) 1.79
Avirulence and altered physiological properties of cystic fibrosis strains of Pseudomonas aeruginosa. Infect Immun (1985) 1.74
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70
Inhibition of Pseudomonas aeruginosa exoenzyme expression by subinhibitory antibiotic concentrations. Antimicrob Agents Chemother (1989) 1.69
Longitudinal study of immune response to Pseudomonas aeruginosa antigens in cystic fibrosis. Infect Immun (1983) 1.68
Phenotypic comparison of Pseudomonas aeruginosa strains isolated from a variety of clinical sites. J Clin Microbiol (1986) 1.60
Specific cleavage of human type III and IV collagens by Pseudomonas aeruginosa elastase. Infect Immun (1986) 1.55
The accessory genome of Pseudomonas aeruginosa. Microbiol Mol Biol Rev (2010) 1.53
Molecular functions of syndecan-1 in disease. Matrix Biol (2011) 1.47
Passive protection against Pseudomonas aeruginosa infection in an experimental leukopenic mouse model. Infect Immun (1983) 1.45
Phenotypic conversion of Pseudomonas aeruginosa in cystic fibrosis. J Clin Microbiol (1990) 1.44
Production of elastase, exotoxin A, and alkaline protease in sputa during pulmonary exacerbation of cystic fibrosis in patients chronically infected by Pseudomonas aeruginosa. J Clin Microbiol (1995) 1.40
Pseudomonas aeruginosa exoproteases inhibit human neutrophil chemiluminescence. Infect Immun (1984) 1.37
Interaction of Pseudomonas aeruginosa alkaline protease and elastase with human polymorphonuclear leukocytes in vitro. Infect Immun (1984) 1.34
Genome-wide study of Pseudomonas aeruginosa outer membrane protein immunogenicity using self-assembling protein microarrays. Infect Immun (2009) 1.30
Characterization of phospholipase C from Pseudomonas aeruginosa as a potent inflammatory agent. Infect Immun (1990) 1.27
Regulation of Vibrio anguillarum empA metalloprotease expression and its role in virulence. Appl Environ Microbiol (2004) 1.20
Pseudomonas aeruginosa alkaline protease degrades human gamma interferon and inhibits its bioactivity. Infect Immun (1988) 1.18
Surface characteristics of Pseudomonas aeruginosa grown in a chamber implant model in mice and rats. Infect Immun (1989) 1.15
Effect of chemotactins released by Staphylococcus aureus and Pseudomonas aeruginosa on the murine respiratory tract. Infect Immun (1985) 1.14
Outer membrane protein F preparation of Pseudomonas aeruginosa as a vaccine against chronic pulmonary infection with heterologous immunotype strains in a rat model. Infect Immun (1988) 1.14
In vitro evidence that human airway lysozyme is cleaved and inactivated by Pseudomonas aeruginosa elastase and not by human leukocyte elastase. Infect Immun (1985) 1.10
A substitution at His-120 in the LasA protease of Pseudomonas aeruginosa blocks enzymatic activity without affecting propeptide processing or extracellular secretion. J Bacteriol (1996) 1.09
Immunization with Pseudomonas aeruginosa vaccines and adjuvant can modulate the type of inflammatory response subsequent to infection. Infect Immun (1994) 1.07
Pulmonary clearance and inflammatory response in C3H/HeJ mice after intranasal exposure to Pseudomonas spp. Appl Environ Microbiol (1993) 1.01
Selective inhibition of the accumulation of extracellular proteases of Pseudomonas aeruginosa by gentamicin and tobramycin. Antimicrob Agents Chemother (1985) 0.99
Comparative in vitro exoenzyme-suppressing activities of azithromycin and other macrolide antibiotics against Pseudomonas aeruginosa. Antimicrob Agents Chemother (1994) 0.99
Inhibitory and stimulatory effects of Pseudomonas aeruginosa pyocyanine on human T and B lymphocytes and human monocytes. Infect Immun (1990) 0.99
Inhibition of human lymphocyte proliferation and cleavage of interleukin-2 by Pseudomonas aeruginosa proteases. Infect Immun (1988) 0.94
Functionally distinct monoclonal antibodies reactive with enzymatically active and binding domains of Pseudomonas aeruginosa toxin A. Infect Immun (1986) 0.93
Characterization of elastase-deficient clinical isolates of Pseudomonas aeruginosa. Infect Immun (1996) 0.92
Effects of Pseudomonas aeruginosa elastase on alveolar epithelial permeability in guinea pigs. Infect Immun (1990) 0.90
Elastolytic activity among staphylococci. J Clin Microbiol (1986) 0.89
Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase. Chem Commun (Camb) (2013) 0.88
Virulence determinants in Pseudomonas aeruginosa strains from urinary tract infections. Epidemiol Infect (1992) 0.87
Pseudomonas aeruginosa PA1006, which plays a role in molybdenum homeostasis, is required for nitrate utilization, biofilm formation, and virulence. PLoS One (2013) 0.87
3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB. ACS Med Chem Lett (2012) 0.85
Disruption of respiratory cilia by proteases including those of Pseudomonas aeruginosa. Infect Immun (1986) 0.82
Prevalence of Pseudomonas aeruginosa and Acinetobacter spp. in subgingival biofilm and saliva of subjects with chronic periodontal infection. Braz J Microbiol (2014) 0.81
Dual-function vaccine for Pseudomonas aeruginosa: characterization of chimeric exotoxin A-pilin protein. Infect Immun (2001) 0.80
Tetradecyltrimethylammonium inhibits Pseudomonas aeruginosa hemolytic phospholipase C induced by choline. Curr Microbiol (2007) 0.78
Elastase Activity in Aspergillus fumigatus Can Arise by Random, Spontaneous Mutations. Int J Evol Biol (2010) 0.77
Mechanism of fibroblast inflammatory responses to Pseudomonas aeruginosa elastase. Microbiology (2014) 0.76
Isolation and characterization of a transposon-induced cytotoxin-deficient mutant of Pseudomonas aeruginosa. Infect Immun (1991) 0.75
Genome-Wide Analysis of Oceanimonas sp. GK1 Isolated from Gavkhouni Wetland (Iran) Demonstrates Presence of Genes for Virulence and Pathogenicity. Cell J (2015) 0.75
Proteolytic cleavage of a C-terminal prosequence, leading to autoprocessing at the N Terminus, activates leucine aminopeptidase from Pseudomonas aeruginosa. J Biol Chem (2009) 0.75
Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes. Int J Mol Sci (2017) 0.75
Genome-Wide Survey of Pseudomonas aeruginosa PA14 Reveals a Role for the Glyoxylate Pathway and Extracellular Proteases in the Utilization of Mucin. Infect Immun (2017) 0.75
Chromosomal genetics of Pseudomonas. Microbiol Rev (1979) 13.65
Isolation and characterization of Pseudomonas aeruginosa PAO mutant that produces altered elastase. J Bacteriol (1980) 5.74
Extracellular toxins of Pseudomonas aeruginosa. J Infect Dis (1974) 5.17
A rat model of chronic respiratory infection with Pseudomonas aeruginosa. Am Rev Respir Dis (1979) 4.27
Toxin A-deficient mutants of Pseudomonas aeruginosa PA103: isolation and characterization. Infect Immun (1980) 3.95
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Passive protection by antitoxin in experimental Pseudomonas aeruginosa burn infections. Infect Immun (1977) 3.25
Toxin inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A. Methods Enzymol (1979) 3.10
Incidence of exotoxin production by Pseudomonas species. Infect Immun (1977) 3.08
Neutralizing antibody to Pseudomonas aeruginosa exotoxin in human sera: evidence for in vivo toxin production during infection. Infect Immun (1976) 2.69
Antibodies to proteases and exotoxin A of Pseudomonas aeruginosa in patients with cystic fibrosis: Demonstration by radioimmunoassay. J Infect Dis (1978) 2.60
Purification and properties of a protease with elastase activity from Pseudomonas aeruginosa. J Gen Microbiol (1977) 2.41
Exotoxin production by clinical isolates of pseudomonas aeruginosa. Infect Immun (1977) 2.38
Corneal infections in mice with toxin A and elastase mutants of Pseudomonas aeruginosa. J Infect Dis (1980) 2.29
Exotoxins of Pseudomonas aeruginosa. 3. Characteristics of antitoxin A. J Infect Dis (1973) 2.12
Pneumonia in an intensive care unit. A 30-month experience. Arch Intern Med (1974) 2.05
Evidence for the role of toxin A in the pathogenesis of infection with Pseudomonas aeruginosa in humans. J Infect Dis (1980) 1.90
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Comparative toxicities of diphtherial toxin and Pseudomonas aeruginosa exotoxin A: evidence for different cell receptors. J Gen Microbiol (1978) 1.52
Isolation and characterization of a Pseudomonas aeruginosa mutant producing a nontoxic, immunologically crossreactive toxin A protein. Proc Natl Acad Sci U S A (1980) 1.50
Inhibitory effect of cystic fibrosis serum on pseudomonas phagocytosis by rabbit and human alveolar macrophages. Pediatr Res (1979) 1.36
Production of alkaline protease by Pseudomonas aeruginosa. J Clin Microbiol (1980) 1.12
Cystic fibrosis: the ciliary inhibitor is a small polypeptide associated with immunoglobulin G. Biochem Biophys Res Commun (1975) 0.84
The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science (1998) 19.92
Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc Natl Acad Sci U S A (1994) 11.44
Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication. Science (1993) 10.85
Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression. J Bacteriol (1991) 9.89
NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,. Proc Natl Acad Sci U S A (1975) 9.15
Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells. Cell (1984) 8.32
A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1995) 7.66
Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J Bacteriol (1997) 7.51
Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol (1997) 6.74
Role of pili in adherence of Pseudomonas aeruginosa to mammalian buccal epithelial cells. Infect Immun (1980) 6.19
Bacterial quorum sensing in pathogenic relationships. Infect Immun (2000) 5.92
Isolation and characterization of Pseudomonas aeruginosa PAO mutant that produces altered elastase. J Bacteriol (1980) 5.74
Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1999) 5.58
Burkholderia thailandensis sp. nov., a Burkholderia pseudomallei-like species. Int J Syst Bacteriol (1998) 5.34
alpha-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences. Nature (1985) 5.30
LasR of Pseudomonas aeruginosa is a transcriptional activator of the alkaline protease gene (apr) and an enhancer of exotoxin A expression. Infect Immun (1993) 4.90
Transformation of Pseudomonas aeruginosa by electroporation. Nucleic Acids Res (1989) 4.75
Cell-to-cell signaling and Pseudomonas aeruginosa infections. Emerg Infect Dis (1999) 4.75
Codon usage in Pseudomonas aeruginosa. Nucleic Acids Res (1988) 4.58
Influence of iron on yields of extracellular products in Pseudomonas aeruginosa cultures. J Bacteriol (1979) 4.43
Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals. J Bacteriol (1999) 4.42
A more sensitive plate assay for detection of protease production by Pseudomanas aeruginosa. J Clin Microbiol (1979) 4.30
Efflux-mediated aminoglycoside and macrolide resistance in Burkholderia pseudomallei. Antimicrob Agents Chemother (1999) 4.29
A rat model of chronic respiratory infection with Pseudomonas aeruginosa. Am Rev Respir Dis (1979) 4.27
Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection. Infect Immun (1996) 4.08
Effect of iron on yields of exotoxin A in cultures of Pseudomonas aeruginosa PA-103. Infect Immun (1978) 4.01
Toxin A-deficient mutants of Pseudomonas aeruginosa PA103: isolation and characterization. Infect Immun (1980) 3.95
Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy. J Bacteriol (1995) 3.91
Isolation of cDNA clones for the human complement protein factor B, a class III major histocompatibility complex gene product. Proc Natl Acad Sci U S A (1982) 3.89
Pseudomonas aeruginosa exoenzyme S: an adenosine diphosphate ribosyltransferase distinct from toxin A. Proc Natl Acad Sci U S A (1978) 3.84
Molecular characterization and nucleotide sequence of the Pseudomonas aeruginosa elastase structural gene. J Bacteriol (1988) 3.83
Characterization and use of a DNA probe as an epidemiological marker for Pseudomonas aeruginosa. J Infect Dis (1987) 3.79
Pseudomonas aeruginosa LasA: a second elastase under the transcriptional control of lasR. Mol Microbiol (1991) 3.73
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Intracellular survival of Burkholderia pseudomallei. Infect Immun (1996) 3.56
Role of fibronectin in the prevention of adherence of Pseudomonas aeruginosa to buccal cells. J Infect Dis (1981) 3.51
Passive protection by antitoxin in experimental Pseudomonas aeruginosa burn infections. Infect Immun (1977) 3.25
Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa. J Bacteriol (1994) 3.24
Role of adherence in the pathogenesis of Pseudomonas aeruginosa lung infection in cystic fibrosis patients. Infect Immun (1980) 3.23
Safety and characterization of the immune response engendered by two combined measles, mumps and rubella vaccines. Vaccine (1998) 3.22
The contribution of exoproducts to virulence of Pseudomonas aeruginosa. Can J Microbiol (1985) 3.21
Mechanism of action of Pseudomonas aeruginosa exotoxin Aiadenosine diphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo. Infect Immun (1977) 3.17
Vfr controls quorum sensing in Pseudomonas aeruginosa. J Bacteriol (1997) 3.10
Toxin inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A. Methods Enzymol (1979) 3.10
Incidence of exotoxin production by Pseudomonas species. Infect Immun (1977) 3.08
Isolation and characterization of transposon-induced mutants of Pseudomonas aeruginosa deficient in production of exoenzyme S. Infect Immun (1984) 3.01
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Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide. Mol Microbiol (1999) 2.95
Functional analysis of the Pseudomonas aeruginosa autoinducer PAI. J Bacteriol (1996) 2.78
Detection of bacterial virulence genes by subtractive hybridization: identification of capsular polysaccharide of Burkholderia pseudomallei as a major virulence determinant. Infect Immun (2001) 2.76
Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosa. J Bacteriol (1999) 2.72
Association of respiratory tract colonization with adherence of gram-negative bacilli to epithelial cells. J Infect Dis (1979) 2.70
Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature (1984) 2.69
Characterization of Burkholderia pseudomallei and Burkholderia pseudomallei-like strains. Epidemiol Infect (1997) 2.69
Contribution of quorum sensing to the virulence of Pseudomonas aeruginosa in burn wound infections. Infect Immun (1999) 2.67
The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol (2000) 2.62
The chain of command in Pseudomonas quorum sensing. Trends Microbiol (1997) 2.56
Polyphosphate kinase is essential for biofilm development, quorum sensing, and virulence of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2000) 2.52
Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant. Microb Pathog (2001) 2.52
The type II O-antigenic polysaccharide moiety of Burkholderia pseudomallei lipopolysaccharide is required for serum resistance and virulence. Mol Microbiol (1998) 2.46
Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection. Infect Immun (2000) 2.40
Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme S synthesis in Pseudomonas aeruginosa. J Bacteriol (1991) 2.39
Role of lipopolysaccharide in virulence of Pseudomonas aeruginosa. Infect Immun (1984) 2.39
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Molecular map of the murine S region. Proc Natl Acad Sci U S A (1983) 2.24
Characterization of Pseudomonas cepacia isolates from patients with cystic fibrosis. J Clin Microbiol (1984) 2.23
Expression in Escherichia coli and function of Pseudomonas aeruginosa outer membrane porin protein F. J Bacteriol (1986) 2.15
RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa. J Bacteriol (1999) 2.14
Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections. Infect Immun (1997) 2.11
Isolation and characterization of alkaline protease-deficient mutants of Pseudomonas aeruginosa in vitro and in a mouse eye model. Infect Immun (1984) 2.11
Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of twitching motility. J Bacteriol (1999) 2.09
Oral Salmonella typhimurium vaccine expressing circumsporozoite protein protects against malaria. Science (1988) 2.09
Evaluation of Pseudomonas aeruginosa exotoxin A and elastase as virulence factors in acute lung infection. Infect Immun (1983) 2.06
Several GTP-binding proteins, including p21c-H-ras, are preferred substrates of Pseudomonas aeruginosa exoenzyme S. J Biol Chem (1989) 2.00
Multidrug efflux pumps: expression patterns and contribution to antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother (2001) 1.96
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Production of exoenzyme S during Pseudomonas aeruginosa infections of burned mice. Infect Immun (1979) 1.86
Identification of a cytotoxin produced by Legionella pneumophila. Infect Immun (1980) 1.83
Use of a cDNA clone for the fourth component of human complement (C4) for analysis of a genetic deficiency of C4 in guinea pig. Proc Natl Acad Sci U S A (1983) 1.82
Demonstration of an iron-siderophore-binding protein in the outer membrane of Pseudomonas aeruginosa. Infect Immun (1983) 1.82
Cloning of cDNA sequences of human adenosine deaminase. Proc Natl Acad Sci U S A (1983) 1.81
Protection against Pseudomonas aeruginosa infection in a murine burn wound sepsis model by passive transfer of antitoxin A, antielastase, and antilipopolysaccharide. Infect Immun (1983) 1.79
Contribution of exoenzyme S to the virulence of Pseudomonas aeruginosa. Antibiot Chemother (1971) (1985) 1.78
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