Published in Biochemistry on March 01, 1983
GAT1 (GABA:Na+:Cl-) cotransport function. Steady state studies in giant Xenopus oocyte membrane patches. J Gen Physiol (1999) 1.41
GAT1 (GABA:Na+:Cl-) cotransport function. Kinetic studies in giant Xenopus oocyte membrane patches. J Gen Physiol (1999) 1.31
An intermediate state of the gamma-aminobutyric acid transporter GAT1 revealed by simultaneous voltage clamp and fluorescence. J Gen Physiol (2000) 1.25
Mutations in the GABA Transporter SLC6A1 Cause Epilepsy with Myoclonic-Atonic Seizures. Am J Hum Genet (2015) 1.09
Sodium-dependent GABA-induced currents in GAT1-transfected HeLa cells. J Physiol (1996) 1.05
Bioenergetics of neurotransmitter transport. J Bioenerg Biomembr (1998) 0.99
Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1. J Physiol (2002) 0.94
Novel properties of a mouse gamma-aminobutyric acid transporter (GAT4). J Membr Biol (2005) 0.88
Microseconds simulations reveal a new sodium-binding site and the mechanism of sodium-coupled substrate uptake by LeuT. J Biol Chem (2014) 0.88
Ezrin mediates tethering of the gamma-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain. Biophys J (2009) 0.86
Structure, function, and plasticity of GABA transporters. Front Cell Neurosci (2014) 0.86
Two pharmacologically distinct sodium- and chloride-coupled high-affinity gamma-aminobutyric acid transporters are present in plasma membrane vesicles and reconstituted preparations from rat brain. Proc Natl Acad Sci U S A (1990) 0.86
The gamma-aminobutyric acid transporter and its interaction with taurine in the apical membrane of the bovine retinal pigment epithelium. Biochem J (1992) 0.84
Elucidating conformational changes in the gamma-aminobutyric acid transporter-1. J Biol Chem (2009) 0.82
Sodium ion-dependent transporters for neurotransmitters: a review of recent developments. Biochem J (1994) 0.78
GATMD: γ-aminobutyric acid transporter mutagenesis database. Database (Oxford) (2010) 0.78
Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue. J Membr Biol (2012) 0.77
Inhibitors of the gamma-aminobutyric acid transporter 1 (GAT1) do not reveal a channel mode of conduction. Neurochem Int (2009) 0.77
Cloning and expression of a rat brain L-glutamate transporter. Nature (1992) 3.14
Cloning and expression of a rat brain GABA transporter. Science (1990) 3.08
Use of neomycin in the isolation of mutants blocked in energy conservation in Escherichia coli. J Bacteriol (1972) 2.00
Active transport of L-glutamate by membrane vesicles isolated from rat brain. Biochemistry (1978) 1.98
Mutation of an amino acid residue influencing potassium coupling in the glutamate transporter GLT-1 induces obligate exchange. J Biol Chem (1997) 1.96
Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter. J Biol Chem (2000) 1.90
Binding order of substrates to the sodium and potassium ion coupled L-glutamic acid transporter from rat brain. Biochemistry (1982) 1.88
Ion binding and permeation at the GABA transporter GAT1. J Neurosci (1996) 1.82
An [Na+ + K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes. Neuroscience (1992) 1.70
Energy conservation in membranes of mutants of Escherichia coli defective in oxidative phosphorylation. Biochim Biophys Acta (1973) 1.64
Biotinylation of single cysteine mutants of the glutamate transporter GLT-1 from rat brain reveals its unusual topology. Neuron (1998) 1.62
Purification and properties of the proton-translocating adenosine triphosphatase complex of bovine heart mitochondria. J Biol Chem (1976) 1.53
The accessibility of a novel reentrant loop of the glutamate transporter GLT-1 is restricted by its substrate. J Biol Chem (2000) 1.46
Crosslinking of the receptors for immunoglobulin E depolarizes the plasma membrane of rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1983) 1.41
Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition. J Biol Chem (1997) 1.32
gamma-Aminobutyric acid transport in reconstituted preparations from rat brain: coupled sodium and chloride fluxes. Biochemistry (1988) 1.30
Coupled, but not uncoupled, fluxes in a neuronal glutamate transporter can be activated by lithium ions. J Biol Chem (2001) 1.27
Glutamate 404 is involved in the substrate discrimination of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain. J Biol Chem (1995) 1.26
Expression of a cloned gamma-aminobutyric acid transporter in mammalian cells. Biochemistry (1992) 1.25
Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter. Proc Natl Acad Sci U S A (1999) 1.25
Molecular determinant of ion selectivity of a (Na+ + K+)-coupled rat brain glutamate transporter. Proc Natl Acad Sci U S A (1998) 1.25
Purification and reconstitution of the sodium- and potassium-coupled glutamate transport glycoprotein from rat brain. Biochemistry (1990) 1.24
Mutation of arginine 44 of GAT-1, a (Na(+) + Cl(-))-coupled gamma-aminobutyric acid transporter from rat brain, impairs net flux but not exchange. J Biol Chem (2000) 1.23
Counterflow of L-glutamate in plasma membrane vesicles and reconstituted preparations from rat brain. Biochemistry (1990) 1.23
Light-dependent proton and rubidium translocation in membrane vesicles from Halobacterium halobium. Biochem Biophys Res Commun (1975) 1.23
Oxidative phosphorylation in mutants of Escherichia coli defective in energy transduction. Biochim Biophys Acta (1972) 1.19
Initial characterization of the calcium channel activated by the cross-linking of the receptors for immunoglobulin E. J Biol Chem (1984) 1.17
Only one of the charged amino acids located in the transmembrane alpha-helices of the gamma-aminobutyric acid transporter (subtype A) is essential for its activity. J Biol Chem (1993) 1.17
Cysteine scanning of the surroundings of an alkali-ion binding site of the glutamate transporter GLT-1 reveals a conformationally sensitive residue. J Biol Chem (1998) 1.16
Localization of the glutamate transporter GLT-1 in rat and macaque monkey retinae. Neurosci Lett (1994) 1.13
Differentiation between mutants of Escherichia coli K defective in oxidative phosphorylation. Biochim Biophys Acta (1975) 1.12
Identification of tryptophan residues critical for the function and targeting of the gamma-aminobutyric acid transporter (subtype A). J Biol Chem (1994) 1.12
Purification and identification of the functional sodium- and chloride-coupled gamma-aminobutyric acid transport glycoprotein from rat brain. J Biol Chem (1986) 1.08
Purification and properties of Mg2+-Ca2+ adenosinetriphosphatase from Escherichia coli. Proc Natl Acad Sci U S A (1974) 1.07
The reactivity of the gamma-aminobutyric acid transporter GAT-1 toward sulfhydryl reagents is conformationally sensitive. Identification of a major target residue. J Biol Chem (1999) 1.07
Active transport of gamma-aminobutyric acid by membrane vesicles isolated from rat brain. Biochemistry (1978) 1.07
Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J Biol Chem (1993) 1.03
The membrane topology of GAT-1, a (Na+ + Cl-)-coupled gamma-aminobutyric acid transporter from rat brain. J Biol Chem (1997) 1.01
Ultrastructural immunocytochemical observations on the localization, metabolism and transport of glutamate in normal and ischemic brain tissue. Prog Brain Res (1992) 1.00
The role of a transmembrane pH gradient in 5-hydroxy tryptamine uptake by synaptic vesicles from rat brain. FEBS Lett (1979) 1.00
Role of a transmembrane pH gradient in epinephrine transport by chromaffin granule membrane vesicles. Proc Natl Acad Sci U S A (1978) 0.99
Active transport in mutants of Escherichia coli with alterations in the membrane ATPase complex. FEBS Lett (1973) 0.98
Bioenergetics of neurotransmitter transport. Biochim Biophys Acta (1983) 0.98
Efflux and exchange of gamma-aminobutyric acid and nipecotic acid catalysed by synaptic plasma membrane vesicles isolated from immature rat brain. Biochim Biophys Acta (1983) 0.94
Immunocytochemical localization of the GABA transporter in rat brain. J Neurosci (1990) 0.94
Histidine 326 is critical for the function of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain. J Biol Chem (1994) 0.94
Cholesterol is required for the reconstruction of the sodium- and chloride-coupled, gamma-aminobutyric acid transporter from rat brain. J Biol Chem (1990) 0.93
Reconstitution and purification of the sodium- and chloride-coupled gamma-aminobutyric acid transporter from rat brain. J Biol Chem (1985) 0.93
Preparation and characterization of homogeneous coupling factor 6 from bovine heart mitochondria. Biochem Biophys Res Commun (1976) 0.91
Glutamate-101 is critical for the function of the sodium and chloride-coupled GABA transporter GAT-1. FEBS Lett (1995) 0.91
Reserpine as a competitive and reversible inhibitor of the catecholamine transporter of bovine chromaffin granules. FEBS Lett (1979) 0.91
Engineered Zn(2+) switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents. J Biol Chem (2001) 0.90
Electrogenic transport of biogenic amines in chromaffin granule membrane vesicles. FEBS Lett (1980) 0.89
Neither amino nor carboxyl termini are required for function of the sodium- and chloride-coupled gamma-aminobutyric acid transporter from rat brain. J Biol Chem (1992) 0.85
Functional asymmetry of the amine transporter from chromaffin granules. J Biol Chem (1983) 0.84
Identification of domains of a cloned rat brain GABA transporter which are not required for its functional expression. FEBS Lett (1993) 0.84
Partial purification of the sodium- and potassium-coupled L-glutamate transport glycoprotein from rat brain. Biochim Biophys Acta (1988) 0.83
Solubilization and reconstitution of the L-glutamic acid transporter from rat brain. FEBS Lett (1978) 0.83
Solubilization and reconstitution of the catecholamine transporter from bovine chromaffin granules. Biochemistry (1979) 0.82
Low-affinity gamma-aminobutyric acid transport in rat brain. Biochemistry (1989) 0.81
A monoclonal antibody against a Na(+)-L-glutamate cotransporter from rat brain. J Biol Chem (1992) 0.79
Comparative analysis of sodium-dependent L-glutamate transport of synaptosomal and astroglial membrane vesicles from mouse cortex. FEBS Lett (1992) 0.79
Modulation of neurotransmitter transport by the activity of the action potential sodium ion channel in membrane vesicles from rat brain. Biochemistry (1980) 0.79
Neuronal and glial gamma-aminobutyric acid+ transporters are distinct proteins. FEBS Lett (1992) 0.78
Efflux of L-glutamate by synaptic plasma membrane vesicles isolated from rat brain. Biochemistry (1982) 0.78
Purification and reconstitution of the phosphate transporter from bovine heart mitochondria. Biochem Biophys Res Commun (1977) 0.78
Active transport of L-proline by membrane vesicles isolated from rat brain. Biochim Biophys Acta (1980) 0.78
Hippocampal gamma-aminobutyric acid and benzodiazepine receptors after early phenobarbital exposure. Brain Res Dev Brain Res (1993) 0.77
Efflux of gamma-aminobutyric acid by synaptic plasma membrane vesicles isolated from rat brain. Biochemistry (1981) 0.77
Transport of 5-hydroxytryptamine in membrane vesicles from rat basophilic leukemia cells. Biochim Biophys Acta (1985) 0.77
Solubilisation and reconstitution of the gamma-aminobutyric acid transporter from rat brain. FEBS Lett (1978) 0.77
Amino acid sequence of bovine heart coupling factor 6. Proc Natl Acad Sci U S A (1984) 0.76
Structural and functional studies on the sodium- and chloride-coupled gamma-aminobutyric acid transporter: deglycosylation and limited proteolysis. Biochemistry (1989) 0.76
Reconstitution and partial purification of the sodium and chloride-coupled glycine transporter from rat spinal cord. Biochim Biophys Acta (1989) 0.75
Thrombin-induced degranulation of cultured bone marrow-derived mast cells: effect on calcium uptake. Immunology (1985) 0.75
Ion-coupled neurotransmitter transport across the synaptic plasma membrane. Ann N Y Acad Sci (1985) 0.75
Active transport of biogenic amines in chromaffin granule membrane vesicles. Monogr Neural Sci (1980) 0.75
The substrates of a sodium- and chloride-coupled gamma-aminobutyric acid transporter protect multiple sites throughout the protein against proteolytic cleavage. Biochemistry (1993) 0.75
Stimulation of adenine nucleotide translocation in reconstituted vesicles by phosphate and the phosphate transporter. Biochem Biophys Res Commun (1977) 0.75