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U Otten

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol 2000 1.80
2 An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues. J Neurochem 1987 1.66
3 Sympathetic neurons can produce and respond to interleukin 6. Proc Natl Acad Sci U S A 1998 1.51
4 Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci U S A 1978 1.50
5 Nerve growth factor gene expression in the developing rat brain. Science 1986 1.41
6 Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase Trk in activated CD4-positive T-cell clones. Proc Natl Acad Sci U S A 1993 1.33
7 Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunity. J Autoimmun 2000 1.32
8 Nerve growth factor (NGF) in the rat CNS: absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra. Brain Res 1979 1.28
9 Nerve growth factor-mediated selective induction of ornithine decarboxylase in rat pheochromocytoma; a cyclic AMP-independent process. FEBS Lett 1978 1.19
10 Multiple sclerosis patients express increased levels of beta-nerve growth factor in cerebrospinal fluid. Neurosci Lett 1992 1.19
11 Inflammatory signals induce neurotrophin expression in human microglial cells. J Neurochem 1998 1.18
12 Dopamine, norepinephrine and serotonin production by an intestinal carcinoid tumor. Cancer 1980 1.16
13 Role of interleukin-6 and soluble IL-6 receptor in region-specific induction of astrocytic differentiation and neurotrophin expression. Glia 1999 1.12
14 Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors. Eur J Neurosci 1999 1.11
15 Interleukin-1 beta and tumor necrosis factor-alpha synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes. Neurosci Lett 1990 1.05
16 Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development. Brain Res 1994 1.05
17 Selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase by nerve growth factor: comparison between adrenal medulla and sympathetic ganglia of adult and newborn rats. Brain Res 1977 1.04
18 Increased levels of NGF in sera of systemic lupus erythematosus patients. Neuroreport 1993 1.03
19 Requirement of nerve growth factor for development of substance P-containing sensory neurones. Nature 1980 0.98
20 Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels. FEBS Lett 1986 0.97
21 Anti-inflammatory activity of nerve growth factor in experimental autoimmune encephalomyelitis: inhibition of monocyte transendothelial migration. Eur J Immunol 2001 0.96
22 Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia. Brain Res 1978 0.96
23 Biochemical and anatomical effects of antibodies against nerve growth factor on developing rat sensory ganglia. Proc Natl Acad Sci U S A 1984 0.95
24 Developmental regulation of nerve growth factor and its receptor in the rat caudate-putamen. Neuron 1989 0.95
25 Expression of functional trk protooncogene in human monocytes. Proc Natl Acad Sci U S A 1993 0.95
26 Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease. Neurosci Lett 1998 0.94
27 Effect of glucocorticoids on nerve growth factor-mediated enzyme induction in organ cultures of rat sympathetic ganglia: enchanced response and reduced time requirement to initiate enzyme induction. J Neurochem 1977 0.94
28 Shape changes induced by biologically active peptides and nerve growth factor in blood platelets of rabbits. Br J Pharmacol 1981 0.94
29 NF-kappaB modulates lipopolysaccharide-induced microglial nerve growth factor expression. Glia 1998 0.93
30 Identification of interleukin-6 (IL-6)-expressing neurons in the cerebellum and hippocampus of normal adult rats. Neurosci Lett 1994 0.93
31 Expression of functional trk tyrosine kinase receptors after T cell activation. J Immunol 1994 0.91
32 Interleukin-6 (IL-6) and its soluble receptor support survival of sensory neurons. J Neurosci Res 1999 0.90
33 Stimulation of the pituitary-adrenocortical axis by nerve growth factor. Nature 1979 0.89
34 Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a-receptors. Neurosci Lett 1997 0.89
35 Interleukin-6 (IL-6) and soluble forms of IL-6 receptors are not altered in cerebrospinal fluid of Alzheimer's disease patients. Neurosci Lett 1997 0.89
36 GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats. Neuropharmacology 2000 0.89
37 Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum. Neurosci Lett 1994 0.88
38 Nerve growth factor antagonizes the neurotoxic action of capsaicin on primary sensory neurones. Nature 1983 0.87
39 Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression. Mol Psychiatry 2000 0.87
40 Heterogeneity of human neuroblastoma cell lines in their proliferative responses to basic FGF, NGF, and EGF: correlation with expression of growth factors and growth factor receptors. J Neurosci Res 1995 0.86
41 Selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase in sympathetic ganglia in organ culture: role of glucocorticoids as modulators. Mol Pharmacol 1976 0.86
42 Modulatory role of glucocorticoids on NGF-mediated enzyme induction in organ cultures of sympathetic ganglia. Brain Res 1976 0.86
43 Beta-amyloid modulates tyrosine kinase B receptor expression in SHSY5Y neuroblastoma cells: influence of the antioxidant melatonin. Neuroscience 2003 0.86
44 Location of an isoproterenol-responsive cyclic AMP pool in adrenergic nerve cell bodies and its relationship to tyrosine 3-monooxygenase induction. Proc Natl Acad Sci U S A 1974 0.86
45 Epidermal growth factor content of submandibular glands is increased in rats with experimentally induced gastric lesions. Scand J Gastroenterol 1988 0.86
46 Nerve growth factor-mediated induction of tyrosine hydroxylase in rat superior cervical ganglia in vitro. J Biol Chem 1978 0.86
47 Expression of interleukin-6 receptor (IL-6R) and gp130 mRNA in PC12 cells and sympathetic neurons: modulation by tumor necrosis factor alpha (TNF-alpha). Brain Res 1996 0.85
48 Activation of gp130 by IL-6/soluble IL-6 receptor induces neuronal differentiation. Eur J Neurosci 1997 0.85
49 GABA(B) receptor expression and cellular localization in gerbil hippocampus after transient global ischemia. Neurosci Lett 2005 0.84
50 Nerve growth factor induces plasma extravasation in rat skin. Eur J Pharmacol 1984 0.84
51 Relationship between the rate of axoplasmic transport and subcellular distribution of enzymes involved in the synthesis of norepinephrine. J Neurochem 1973 0.84
52 Nerve growth factor (NGF) regulates tachykinin gene expression and biosynthesis in rat sensory neurons during early postnatal development. Neuropeptides 1993 0.84
53 Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus. Neurosci Lett 1993 0.84
54 Increased CSF levels of nerve growth factor in patients with Alzheimer's disease. Neurology 2000 0.83
55 Nerve growth factor as a mediator of information between effector organs and innervating neurons. Symp Soc Dev Biol 1978 0.83
56 Immunization of adult rats against 2.5 S NGF: effects on the peripheral sympathetic nervous system. Brain Res 1979 0.83
57 Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease. Eur Neurol 2000 0.83
58 Age-dependent time course of cerebral brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 in APP23 transgenic mice. J Neurosci Res 2008 0.82
59 Effects of antibodies against nerve growth factor on the postnatal development of substance P-containing sensory neurons. Neurosci Lett 1982 0.82
60 Nerve growth factor expression in the developing hippocampus isolated in vitro. Dev Biol 1990 0.82
61 Immunosympathectomy: lack of evidence for a complement-mediated cytotoxic mechanism. Brain Res 1980 0.81
62 Circadian rhythm of tyrosine hydroxylase induction by short-term cold stress: modulatory action of glucocorticoids in newborn and adult rats. Proc Natl Acad Sci U S A 1975 0.81
63 Mechanisms of tyrosine hydroxylase and dopamine beta-hydroxylase induction in organ cultures of rat sympathetic ganglia by potassium depolarization and cholinomimetics. Naunyn Schmiedebergs Arch Pharmacol 1976 0.81
64 Alterations in neurotrophins and neurotrophin receptors in Alzheimer's disease. J Neural Transm Suppl 2000 0.81
65 Biosynthesis and release of tachykinins from rat sensory neurons in culture. J Neurosci Res 1991 0.81
66 Organ culture of the rat adrenal medulla: a model system for the study of trans-synaptic enzyme induction. J Neurochem 1975 0.81
67 Fimbria-fornix lesion increases nerve growth factor content in adult rat septum and hippocampus. Neurosci Lett 1986 0.80
68 Postnatal expression of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) mRNAs in rat sympathetic and sensory ganglia. Brain Res 1996 0.80
69 Biological importance of the retrograde axonal transport of nerve growth factor in sensory neurons. Proc Natl Acad Sci U S A 1981 0.80
70 Neurotrophin expression modulated by glucocorticoids and oestrogen in immortalized hippocampal neurons. Brain Res Mol Brain Res 1995 0.80
71 Permissive action of glucocorticoids in induction of tyrosine hydroxylase by nerve growth factor in a pheochromocytoma cell line. Brain Res 1980 0.79
72 Correlation between substance P content of primary sensory neurones and pain sensitivity in rats exposed to antibodies to nerve growth factor. Eur J Pharmacol 1982 0.79
73 Nerve growth factor from the venom of the Chinese cobra Naja naja atra: purification and description of non-neuronal activities. Toxicon 1995 0.79
74 Interleukin-1 beta and tumor necrosis factor-alpha synergistically stimulate nerve growth factor synthesis in rat mesangial cells. Am J Physiol 1991 0.79
75 Modulation of mRNA expression of the neurotrophins of the nerve growth factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. I. Expression of nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin 4 mRNA. Exp Brain Res 1998 0.79
76 Axoplasmic transport of enzymes involved in the synthesis of noradrenaline: relationship between the rate of transport and subcellular distribution. Brain Res 1973 0.78
77 Molecular events in trans-synaptic regulation of the synthesis of macromolecules. Essays Neurochem Neuropharmacol 1977 0.78
78 The role of sodium influx mediated by nicotinic receptors as an initial event in trans-synaptic induction of tyrosine hydroxylase in adrenergic neurons. Naunyn Schmiedebergs Arch Pharmacol 1980 0.78
79 NGF: not just for neurons. Cell Biol Int 1995 0.78
80 On the role of RNA synthesis in the selective induction of tyrosine hydroxylase by nerve growth factor. Brain Res 1978 0.78
81 Effects of perinatal hypo- and hyperthyroidism on the levels of nerve growth factor and its low-affinity receptor in cerebellum. Brain Res Dev Brain Res 1993 0.78
82 Interleukin-6 and interleukin-6 receptor mRNA expression in rat central nervous system. Ann N Y Acad Sci 1995 0.78
83 Effect of hypophysectomy on cAMP changes in rat adrenal medulla evoked by catecholamines and carbamylcholine. Naunyn Schmiedebergs Arch Pharmacol 1975 0.78
84 Proteolytic cleavage of inducible nitric oxide synthase (iNOS) by calpain I. Biochim Biophys Acta 2001 0.78
85 Expression of GABA(A) receptors by reactive astrocytes in explant and primary cultures of rat CNS. Int J Dev Neurosci 1997 0.78
86 Expression of interleukin-6 (IL-6) and IL-6 receptor mRNAs in rat adrenal medulla. Neurosci Lett 1995 0.78
87 Postnatal ontogeny of the neurotrophin receptors trk and trkB mRNA in rat sensory and sympathetic ganglia. Neurosci Lett 1994 0.77
88 Axotomy-induced c-JUN expression in young medial septal neurons is regulated by nerve growth factor. Neuroscience 1998 0.77
89 Effects of pre- and postnatal administration of antibodies to nerve growth factor on the morphological and biochemical development of the rat adrenal medulla: a reinvestigation. Brain Res 1986 0.77
90 Nerve growth factor increases in adult rat brain after hypoxic injury. Neurosci Lett 1989 0.77
91 Mechanism of action and possible sites of synthesis of nerve growth factor. Prog Brain Res 1979 0.77
92 Effect of bilateral decortication on nerve growth factor content in basal nucleus and neostriatum of adult rat brain. Brain Res 1988 0.77
93 Glucocorticoids, neurotrophins and neurodegeneration. J Steroid Biochem Mol Biol 1995 0.77
94 Developmental neurotrophin expression in slice cultures of rat hippocampus. Neurosci Lett 1993 0.77
95 Neuronotrophic factors released by C6 glioma cells. J Neurochem 1988 0.77
96 Modulatory role of platelet-derived growth factor on cytokine-induced nerve growth factor synthesis in rat glomerular mesangial cells. Biochem J 1995 0.77
97 Expression of interleukin-6 and its receptor in the sciatic nerve and cultured Schwann cells: relation to 18-kD fibroblast growth factor-2. Brain Res 2000 0.77
98 Role of nerve growth factor in the development of peptide-containing primary afferent neurons. Monogr Neural Sci 1983 0.77
99 Oxidative stress modulates tyrosine kinase receptor A and p75 receptor (low-affinity nerve growth factor receptor) expression in SHSY5Y neuroblastoma cells. Neurol Clin Neurophysiol 2002 0.76
100 Long-term cultivation of cryopreserved human fetal brain cells in a chemically defined medium. J Neurosci Methods 1989 0.76
101 Spreading depression induces c-fos-like immunoreactivity and NGF mRNA in the rat cerebral cortex. Brain Res 1993 0.76
102 Role of cyclic nucleotides in NGF-mediated induction of tyrosine hydroxylase in rat sympathetic ganglia and adrenal medulla. Brain Res 1978 0.76
103 Acidic FGF induces NGF and its mRNA in the injured neocortex of adult animals. Brain Res Mol Brain Res 1995 0.76
104 Stimulation of the pituitary-adrenocortical axis and induction of tyrosine hydroxylase by nerve growth factor are not dependent on mouse submaxillary gland isorenin. Brain Res 1981 0.76
105 Expression of low-affinity NGF receptor and trkB mRNA in human SH-SY5Y neuroblastoma cells. FEBS Lett 1993 0.76
106 Labelling of Schwann and satellite cells by [3H]dexamethasone in a rat sympathetic ganglion and sciatic nerve. Neuroscience 1981 0.75
107 [Aggressiveness of the rat following combined treatment with monomaime oxidase inhibitors and other psychotropic drugs, especially thymoleptics]. Naunyn Schmiedebergs Arch Pharmakol 1969 0.75
108 [Clogestone acetate, a new orally effective progestagen]. Arch Gynakol 1970 0.75
109 Possible role of cytochrome P450 in inactivation of testosterone in immortalized hippocampal neurons. Brain Res 1997 0.75
110 Synthesis, subcellular distribution and turnover of dopamine beta-hydroxylase in organ cultures of sympathetic ganglia and adrenal medullae. J Neurochem 1976 0.75
111 Influence of phenytoin on cytoskeletal organization and cell viability of immortalized mouse hippocampal neurons. Brain Res 1993 0.75
112 Modulation of mRNA expression of the neurotrophins of the nerve-growth-factor family and their receptors in the septum and hippocampus of rats after transient postnatal thyroxine treatment. II. Effects on p75 and trk receptor expression. Exp Brain Res 1999 0.75
113 Nerve growth factor increases substance P, cholecystokinin and vasoactive intestinal polypeptide immunoreactivities in primary sensory neurones of newborn rats. Neurosci Lett 1982 0.75
114 [Off. Gesundh.-Wes. 50 (1988) 670-677, "Legal-social observations on prostitution in relation to AIDS and AIDS-complex by E. Quambusch]. Offentl Gesundheitswes 1989 0.75
115 Proceedings: Circadian rhythm of tyrosine hydroxylase induction by short-term cold stress. Naunyn Schmiedebergs Arch Pharmacol 1975 0.75
116 [Family-suited living]. Offentl Gesundheitswes 1984 0.75
117 Increased synthesis of dopamine beta-hydroxylase in cultured rat adrenal medullae after in vivo administration of reserpine. J Neurochem 1976 0.75
118 Lack of correlation between changes in cyclic nucleotides and subsequent induction of tyrosine hydroxylase in rat adrenal medulla. Naunyn Schmiedebergs Arch Pharmacol 1976 0.75
119 Sympathectomy inhibits growth of a murine plasmacytoma tumor. J Auton Nerv Syst 1985 0.75
120 Glucocorticoid modulation of neurotrophin expression in immortalized mouse hippocampal neurons. Neurosci Lett 1993 0.75
121 Evidence against a causal relationship between increase in c-AMP and induction of tyrosine hydroxylase in the rat adrenal medulla. Naunyn Schmiedebergs Arch Pharmacol 1974 0.75
122 Short- and long-term effects of vinblastine on the rat adrenal medulla. An ultrastructural and biochemical study. Cell Tissue Res 1979 0.75
123 Expression of the cholecystokinin gene in rat hippocampal interneurons is independent of extrinsic input. Neurosci Lett 1994 0.75
124 Cholinergic but not monoaminergic denervation increases nerve growth factor content in the adult rat hippocampus and cerebral cortex. Naunyn Schmiedebergs Arch Pharmacol 1986 0.75
125 [Vaccination project for vocational students]. Gesundheitswesen 1997 0.75
126 Expression of neurotrophins and the low-affinity NGF receptor in septal and hippocampal reaggregate cultures: local physiologic effects of NGF synthesized in the septal region. Brain Res Dev Brain Res 1992 0.75
127 Substance P modulates the release of locally synthesized nerve growth factor from rat saphenous nerve neuroma. Naunyn Schmiedebergs Arch Pharmacol 1987 0.75
128 Time course of the elevation of nerve growth factor (NGF) content in the hippocampus and septum following lesions of the septohippocampal pathway in rats. Brain Res 1986 0.75
129 [Aggression-inducing combinations of psychotomimetic drugs]. Naunyn Schmiedebergs Arch Pharmakol 1969 0.75
130 [Nerve growth factor-induced axon growth and its antagonism with dexamethasone: in vitro studies on adrenal medulla cells]. Verh Anat Ges 1978 0.75
131 Biochemical effects of nerve growth factor and its antibody on the vas defferens and the adrenal medulla. Neurosci Lett 1978 0.75
132 Studies of gangliosides in diverse nerve cell cultures. Adv Exp Med Biol 1984 0.75
133 Measurement of human nerve growth factor binding sites in brain and in peripheral tissues by a specific immunoprecipitation assay. Naunyn Schmiedebergs Arch Pharmacol 1990 0.75
134 [Microtubules, catecholamines and enzymes of catecholamine synthesis in adrenal chromaffin cells following treatment with vinblastine (demonstration)]. Verh Anat Ges 1978 0.75
135 Endogenous opioid peptides. Bull Soc Sci Med Grand Duche Luxemb 1981 0.75