Published in Proc Natl Acad Sci U S A on July 01, 1978
Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids. Proc Natl Acad Sci U S A (1995) 1.95
The nerve growth factor: thirty-five years later. EMBO J (1987) 1.88
Molecular markers of neuroendocrine development and evidence of environmental regulation. Proc Natl Acad Sci U S A (1987) 1.84
Regulation of the differentiation of PC12 pheochromocytoma cells. Environ Health Perspect (1989) 1.62
Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Mol Cell Biol (1987) 1.42
Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor. Proc Natl Acad Sci U S A (1979) 1.20
A rat gene with sequence homology to the Drosophila gene hairy is rapidly induced by growth factors known to influence neuronal differentiation. Mol Cell Biol (1993) 1.18
Signals and switches in Mammalian neural crest cell differentiation. Cold Spring Harb Perspect Biol (2013) 1.17
Human melanoma cells have both nerve growth factor and nerve growth factor-specific receptors on their cell surfaces. Proc Natl Acad Sci U S A (1979) 1.09
Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla. Stem Cells Transl Med (2012) 1.05
The effect of in vivo hydrocortisone administration on the labelling index and size of the intra- and extra-adrenal chromaffin tissue of the fetal and perinatal mouse. J Anat (1985) 1.01
Purification and partial characterization of a cholinergic neuronal differentiation factor. Proc Natl Acad Sci U S A (1985) 0.99
A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture. J Physiol (1992) 0.96
In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas. Am J Pathol (1997) 0.93
Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling. J Neuroendocrinol (2013) 0.91
Inactivation characteristics reveal two calcium currents in adult bovine chromaffin cells. J Physiol (1991) 0.91
Activity-dependent and -independent synaptic interactions during reinnervation of partially denervated rat muscle. J Physiol (1988) 0.89
The chromaffin cell: paradigm in cell, developmental and growth factor biology. J Anat (1993) 0.88
C6 glioma cell-conditioned medium induces neurite outgrowth and survival of rat chromaffin cells in vitro: comparison with the effects of nerve growth factor. Proc Natl Acad Sci U S A (1984) 0.87
Schwannoma-derived growth factor promotes the neuronal differentiation and survival of PC12 cells. J Cell Biol (1992) 0.85
Oncogene N-ras mediates selective inhibition of c-fos induction by nerve growth factor and basic fibroblast growth factor in a PC12 cell line. Mol Cell Biol (1990) 0.82
Subunit composition and role of Na+,K+-ATPases in adrenal chromaffin cells. J Physiol (2005) 0.81
Past, present and future of human chromaffin cells: role in physiology and therapeutics. Cell Mol Neurobiol (2010) 0.81
Asthma pregnancy alters postnatal development of chromaffin cells in the rat adrenal medulla. PLoS One (2011) 0.80
Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One (2014) 0.80
Sympathetic neurons and chromaffin cells share a common progenitor in the neural crest in vivo. Neural Dev (2013) 0.79
Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development. Neural Dev (2008) 0.79
Transformation of adrenal medullary chromaffin cells increases asthmatic susceptibility in pups from allergen-sensitized rats. Respir Res (2012) 0.79
Noradrenaline transport and transporter mRNA of rat chromaffin cells are controlled by dexamethasone and nerve growth factor. J Physiol (1996) 0.79
Insulin-like growth factors act synergistically with basic fibroblast growth factor and nerve growth factor to promote chromaffin cell proliferation. Proc Natl Acad Sci U S A (1994) 0.78
Prolonged survival of bovine adrenal chromaffin cells in rat cerebral ventricles. Proc Natl Acad Sci U S A (1980) 0.78
Nerve growth factor-induced endocytosis of TWIK-related acid-sensitive K⁺ 1 channels in adrenal medullary cells and PC12 cells. Pflugers Arch (2013) 0.78
Effects of ACTH and aminoglutethimide on the catecholamine content and chromaffin cell morphology of the adrenal medulla of the neonatal rat. J Anat (1993) 0.77
Kidney-tonifying recipe can repair alterations in adrenal medullary chromaffin cells in asthmatic rats. Evid Based Complement Alternat Med (2012) 0.77
Adrenal Medullary Nodules in Beckwith-Wiedemann Syndrome Resemble Extra-Adrenal Paraganglia. Endocr Pathol (1996) 0.76
The effect of unilateral adrenalectomy on transformation of adrenal medullary chromaffin cells in vivo: a potential mechanism of asthma pathogenesis. PLoS One (2012) 0.76
Nerve growth factor. Physiol Rev (1968) 9.12
The nerve growth factor: purification as a 30,000-molecular-weight protein. Proc Natl Acad Sci U S A (1969) 7.14
Surface movements during the growth of single explanted neurons. Proc Natl Acad Sci U S A (1970) 4.12
Primary cultures of dissociated sympathetic neurons. I. Establishment of long-term growth in culture and studies of differentiated properties. J Cell Biol (1973) 3.87
The nerve growth factor: its mode of action on sensory and sympathetic nerve cells. Harvey Lect (1966) 2.93
The migration and differentiation of neural crest cells. Adv Morphog (1970) 2.85
A methodological approach to rapid and sensitive monoamine histofluorescence using a modified glyoxylic acid technique: the SPG method. Histochemistry (1976) 2.03
The mechanism of the differential staining reaction for adrenaline-and noreadrenaline-storing granules in tissues fixed in glutaraldehyde. J Anat (1966) 1.65
Tyrosine hydroxylase in rat brain--cofactor requirements, regional and subcellular distribution. Biochem Pharmacol (1972) 1.49
Growth characteristics of adrenergic nerves in the adult rat. Fluorescence histochemical and 3H-noradrenaline uptake studies using tissue transplantations to the anterior chamber of the eye. Acta Physiol Scand Suppl (1970) 1.45
Comparative studies on the effect of the nerve growth factor on sympathetic ganglia and adrenal medulla in newborn rats. Brain Res (1972) 1.44
Tissue culture assay of nerve growth factor and of the specific antiserum. Exp Cell Res (1970) 1.44
Dynamics and mechanics of corticosteroid feedback at the hypothalamus and anterior pituitary gland. J Endocrinol (1977) 1.25
Selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase by nerve growth factor: comparison between adrenal medulla and sympathetic ganglia of adult and newborn rats. Brain Res (1977) 1.04
Growth characteristics of postnatal rat adrenal medulla in culture. A study correlating phase contrast, microcinematographic, histochemical, and electron microscopical observations. Cell Tissue Res (1977) 0.98
Production of nerve growth factor by the mouse adrenal medulla. Nature (1976) 0.92
Development of the adrenal medullary cells in rats with reference to synaptogenesis. Cell Tissue Res (1977) 0.90
Studies on the interactions between nerve fibres from para- and orthosympathetic ganglia and adreno-cortical and -medullary cells in joint culture. Cell Tissue Res (1977) 0.82
Early effects of nerve growth factor on adrenergic neurons: an electron microscopic morphometric study of the rat superior cervical ganglion. Cell Tissue Res (1975) 0.82
Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci U S A (1995) 5.25
Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-Hydroxydopamine. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 4.85
Physiology of nerve growth factor. Physiol Rev (1980) 4.58
Essential role for TrkB receptors in hippocampus-mediated learning. Neuron (1999) 4.20
Molecular cloning and expression of brain-derived neurotrophic factor. Nature (1989) 3.90
Purification of a new neurotrophic factor from mammalian brain. EMBO J (1982) 3.68
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev (1995) 3.41
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature (1992) 3.39
The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J (1984) 3.39
Neurotrophin-evoked rapid excitation through TrkB receptors. Nature (1999) 3.11
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat Med (1997) 2.95
The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60
Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J (1990) 2.54
Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature (1988) 2.47
Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol (1987) 2.40
Increase in tyrosine hydroxylase activity after reserpine administration. J Pharmacol Exp Ther (1969) 2.32
Disruption of the CNTF gene results in motor neuron degeneration. Nature (1993) 2.22
Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex. Proc Natl Acad Sci U S A (1992) 2.19
Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc Natl Acad Sci U S A (1983) 2.17
Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci U S A (1996) 2.10
Some pharmacological actions of the beta-adrenolytic agent Ro 3-3528 (6,7-dimethyl-alpha-[(isopropylamino) methyl]-2-benzofuranmethanol Hydrochloride). Angiologica (1967) 2.10
A role for BDNF in mechanosensation. Nat Neurosci (1998) 2.08
Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity. Neuron (2001) 2.06
Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature (1990) 2.06
An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia (1968) 1.98
Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci U S A (1997) 1.96
Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proc Natl Acad Sci U S A (1971) 1.96
Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J (1985) 1.93
Relation between the rate of stimulation and the quantity of noradrenaline liberated from sympathetic nerve endings in the isolated perfused spleen of the cat. J Physiol (1965) 1.92
Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J Cell Biol (1992) 1.87
Dual site of action of phenoxybenzamine in the cat's spleen; blockade of alpha-adrenergic receptors and inhibition of re-uptake of neurally released norepinephrine. Experientia (1964) 1.83
Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J Neurosci (1985) 1.82
Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol (2000) 1.80
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature (1990) 1.80
Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci U S A (1991) 1.79
NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res (1983) 1.77
Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor. Nature (1987) 1.76
Characterization of nerve growth factor (NGF) release from hippocampal neurons: evidence for a constitutive and an unconventional sodium-dependent regulated pathway. Eur J Neurosci (1995) 1.72
Increased tyrosine hydroxylase activity after drug-induced alteration of sympathetic transmission. Nature (1969) 1.72
Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J (1984) 1.71
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature (1993) 1.71
The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus. Neuroreport (1993) 1.70
Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages. Proc Natl Acad Sci U S A (1987) 1.70
Sensory neurons in culture: changing requirements for survival factors during embryonic development. Proc Natl Acad Sci U S A (1980) 1.69
Central adrenergic neurones and the initiation and development of experimental hypertension. Experientia (1972) 1.67
Trans-synaptic induction of adrenal tyrosine hydroxylase. J Pharmacol Exp Ther (1969) 1.67
An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues. J Neurochem (1987) 1.66
Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol (1992) 1.64
Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci (1986) 1.64
Electronmicroscopic localization of 5-hydroxydopamine (3,4,5-trihydroxy-phenyl-ethylamine), a new 'false' sympathetic transmitter. Experientia (1967) 1.61
Nerve growth factor in mouse and rat serum: correlation between bioassay and radioimmunoassay determinations. Proc Natl Acad Sci U S A (1978) 1.59
Positive feedback between acetylcholine and the neurotrophins nerve growth factor and brain-derived neurotrophic factor in the rat hippocampus. Eur J Neurosci (1994) 1.57
Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol (1985) 1.57
Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc Natl Acad Sci U S A (1997) 1.55
Potentiation by tetraethylammonium of the response of the cat spleen to postganglionic sympathetic nerve stimulation. J Pharmacol Exp Ther (1967) 1.54
Localization and actions of transforming growth factor-beta s in the embryonic nervous system. Development (1991) 1.53
Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci (1990) 1.53
Specificity of the retrograde axonal transport of nerve growth factor. Brain Res (1974) 1.52
Sympathetic neurons can produce and respond to interleukin 6. Proc Natl Acad Sci U S A (1998) 1.51
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J Cell Biol (1992) 1.51
Ciliary neurotrophic factor: pharmacokinetics and acute-phase response in rat. Ann Neurol (1994) 1.49
Purification of nerve growth factor antibodies by affinity chromatography. J Neurochem (1976) 1.49
Establishment, characterization and fibre outgrowth of isolated bovine adrenal medullary cells in long-term cultures. Neuroscience (1980) 1.48
Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons. Proc Natl Acad Sci U S A (1987) 1.47
Chemical sympathectomy of the cat with 6-hydroxydopamine. J Pharmacol Exp Ther (1969) 1.46
Basic fibroblast growth factor (bFGF) immunoreactivity is present in chromaffin granules. J Neurochem (1990) 1.45
Comparative studies on the effect of the nerve growth factor on sympathetic ganglia and adrenal medulla in newborn rats. Brain Res (1972) 1.44
Construction and properties of recombinant plasmids containing the rII genes of bacteriophage T4. Mol Gen Genet (1978) 1.43
Nerve growth factor gene expression in the developing rat brain. Science (1986) 1.41
Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons. Brain Res (1975) 1.40
Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity. J Neurobiol (1994) 1.40
Expression of a novel member of the TGF-beta superfamily, growth/differentiation factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult rat tissues. Cell Tissue Res (1999) 1.37
Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. J Neurosci (1992) 1.37
Relationship between NGF-mediated volume increase and "priming effect" in fast and slow reacting clones of PC12 pheochromocytoma cells. Role of cAMP. Exp Cell Res (1983) 1.36
Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation. Neuron (1996) 1.36
Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron (1996) 1.35
Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor. Mol Cell Neurosci (1997) 1.33
Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase Trk in activated CD4-positive T-cell clones. Proc Natl Acad Sci U S A (1993) 1.33
The physiological function of nerve growth factor in the central nervous system: comparison with the periphery. Rev Physiol Biochem Pharmacol (1987) 1.33
Adrenal tyrosine hydroxylase: compensatory increase in activity after chemical sympathectomy. Science (1969) 1.33
Production of neurotrophins by activated T cells: implications for neuroprotective autoimmunity. J Autoimmun (2000) 1.32
Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain. J Cell Biol (1991) 1.30
Mechanism of amphetamine accumulation in the isolated perfused heart of the rat. J Pharm Pharmacol (1968) 1.30
Cellular localization of nerve growth factor synthesis by in situ hybridization. EMBO J (1987) 1.28
[Research on the problem of a cholinergic link in postganglionic sympathetic transmission]. Helv Physiol Pharmacol Acta (1966) 1.28
Nerve growth factor (NGF) in the rat CNS: absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra. Brain Res (1979) 1.28
GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron (1996) 1.28
Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport. J Cell Biol (1979) 1.28
Induction of tyrosine hydroxylase in peripheral and central adrenergic neurones by cold-exposure of rats. Nature (1970) 1.27
Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts. J Biol Chem (1988) 1.27
Inhibition of trans-synaptically increased tyrosine hydroxylase activity by cycloheximide and actinomycin D. Mol Pharmacol (1969) 1.27
In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells. EMBO J (1987) 1.25
Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1). Gene (1999) 1.25
GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro. Development (1995) 1.25
Inhibition of exocytosis by intracellularly applied antibodies against a chromaffin granule-binding protein. Nature (1989) 1.25
Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos. Proc Natl Acad Sci U S A (1990) 1.24
TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity. EMBO J (1995) 1.23
Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons. Mol Cell Neurosci (1996) 1.23
New factor released by cultured glioma cells supporting survival and growth of sensory neurones. Nature (1978) 1.23