Published in Cold Spring Harb Symp Quant Biol on January 01, 1980
Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. Proc Natl Acad Sci U S A (1987) 7.38
Extreme instability of myc mRNA in normal and transformed human cells. Proc Natl Acad Sci U S A (1984) 5.09
Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection. Mol Cell Biol (1983) 4.15
Chinese hamster polyadenylated messenger ribonucleic acid: relationship to non-polyadenylated sequences and relative conservation during messenger ribonucleic acid processing. Mol Cell Biol (1981) 2.00
Herpes simplex virus-induced changes in cellular and adenovirus RNA metabolism in an adenovirus type 5-transformed human cell line. J Virol (1982) 1.90
Control of adenovirus early gene expression: posttranscriptional control mediated by both viral and cellular gene products. Mol Cell Biol (1981) 1.68
Involvement of the 5'-leader sequence in coupling the stability of a human H3 histone mRNA with DNA replication. Proc Natl Acad Sci U S A (1986) 1.47
Cycloheximide stimulates early adenovirus transcription if early gene expression is allowed before treatment. J Virol (1983) 1.43
Isolation of a cDNA clone for mouse urinary proteins: age- and sex-related expression of mouse urinary protein genes is transcriptionally controlled. Proc Natl Acad Sci U S A (1981) 1.37
Regulation of early adenovirus gene expression. Microbiol Rev (1987) 1.34
Latent and viral replicative transcription in vivo from the BamHI K fragment of Epstein-Barr virus DNA. J Virol (1985) 1.29
Ability of nonpermissive mouse cells to express a simian virus 40 late function(s). J Virol (1981) 1.21
Induced heat shock mRNAs escape the nucleocytoplasmic transport block in adenovirus-infected HeLa cells. Mol Cell Biol (1987) 1.19
Expression of adenovirus-2 early region 4: assignment of the early region 4 polypeptides to their respective mRNAs, using in vitro translation. J Virol (1982) 1.15
Effects of adeno-associated virus on adenovirus replication and gene expression during coinfection. J Virol (2006) 1.05
Shuffling adenovirus promoters: a viral recombinant with early region 1A under late transcriptional control. EMBO J (1983) 1.00
Control of adenovirus gene expression: cellular gene products restrict expression of adenovirus host range mutants in nonpermissive cells. J Virol (1983) 0.99
Stabilities and interrelations of multiple species of human adenovirus type 5 early region 1 proteins in infected and transformed cells. J Virol (1985) 0.93
Functional analysis of the adenovirus type 5 DNA-binding protein: site-directed mutants which are defective for adeno-associated virus helper activity. J Virol (1986) 0.87
Sequence arrangement and protein coding capacity of the adenovirus type 2 "i" leader. J Virol (1983) 0.86
Stat3 as an oncogene. Cell (1999) 17.39
Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol (2002) 15.33
Predicting the clinical status of human breast cancer by using gene expression profiles. Proc Natl Acad Sci U S A (2001) 13.30
POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNA. Proc Natl Acad Sci U S A (1963) 12.17
Evidence for virus-specific noncapsid proteins in poliovirus-infected HeLa cells. Proc Natl Acad Sci U S A (1965) 11.84
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science (1994) 11.33
An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA. Proc Natl Acad Sci U S A (1971) 11.01
Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res (1985) 10.76
Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA. Science (1971) 10.54
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell (1995) 10.16
The E2F transcription factor is a cellular target for the RB protein. Cell (1991) 9.62
Variety in the level of gene control in eukaryotic cells. Nature (1982) 9.61
Mechanism of activation of early viral transcription by the adenovirus E1A gene product. Cell (1981) 9.38
Transcriptional control in the production of liver-specific mRNAs. Cell (1981) 9.35
The well-built clinical question: a key to evidence-based decisions. ACP J Club (1995) 8.57
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem (1995) 8.52
Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature (1993) 6.84
Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product. Cell (1982) 6.78
Internists' attitudes about clinical practice guidelines. Ann Intern Med (1994) 6.55
More informative abstracts of articles describing clinical practice guidelines. Ann Intern Med (1993) 6.54
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev (2000) 6.54
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science (1993) 6.44
The role of STATs in transcriptional control and their impact on cellular function. Oncogene (2000) 6.42
Identification of a cellular transcription factor involved in E1A trans-activation. Cell (1986) 6.36
Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicing. Cell (1978) 6.36
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev (1990) 6.33
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol Cell Biol (1995) 6.26
The pathway of eukaryotic mRNA formation. Annu Rev Biochem (1983) 6.16
Ribonucleic acids from animal cells. Bacteriol Rev (1968) 6.13
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science (1992) 6.09
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev (1988) 6.08
Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element. Cell (1983) 5.91
Aspects of the synthesis of poliovirus RNA and the formation of virus particles. Virology (1966) 5.85
Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A (1997) 5.83
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell (1994) 5.79
The primary transcription unit of the mouse beta-major globin gene. Cell (1981) 5.75
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev (1992) 5.73
Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science (1992) 5.71
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci U S A (1992) 5.50
Extreme instability of myc mRNA in normal and transformed human cells. Proc Natl Acad Sci U S A (1984) 5.09
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. Genes Dev (1989) 5.09
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol Cell Biol (2001) 5.03
Selection and preliminary characterization of temperature-sensitive mutants of type 5 adenovirus. J Virol (1972) 4.96
Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev (1994) 4.93
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science (1995) 4.90
Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses. Proc Natl Acad Sci U S A (1986) 4.89
Requirement of a downstream sequence for generation of a poly(A) addition site. Cell (1984) 4.87
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet (1996) 4.84
Transcriptional induction of two genes in human cells by beta interferon. Proc Natl Acad Sci U S A (1984) 4.84
Rapidly labeled HeLa cell nuclear RNA. I. Identification by zone sedimentation of a heterogeneous fraction separate from ribosomal precursor RNA. J Mol Biol (1966) 4.83
Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues. Nucleic Acids Res (1984) 4.79
Common control of the heat shock gene and early adenovirus genes: evidence for a cellular E1A-like activity. Mol Cell Biol (1984) 4.76
The initiation sites for RNA transcription in Ad2 DNA. Cell (1977) 4.76
Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control. Proc Natl Acad Sci U S A (1987) 4.68
A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science (1993) 4.65
Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci U S A (1987) 4.61
Identification of the membrane protein and "core" protein of Sindbis virus. Proc Natl Acad Sci U S A (1968) 4.52
Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication. Proc Natl Acad Sci U S A (1971) 4.48
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes. Mol Cell Biol (1989) 4.47
Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing. Nature (1981) 4.46
Characterization of a new low molecular weight RNA in HeLa cell ribosomes. J Mol Biol (1968) 4.44
Sindbis virus infection of chick and hamster cells: synthesis of virus-specific proteins. Virology (1969) 4.38
The E2F1-3 transcription factors are essential for cellular proliferation. Nature (2001) 4.37
The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations. J Cell Biol (1989) 4.36
Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways. EMBO J (1993) 4.35
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27
Screening for breast cancer. Br Med J (1976) 4.23
Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection. Mol Cell Biol (1983) 4.15
The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: mapping by effects of ultraviolet irradiation. Cell (1977) 4.13
ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains. Proc Natl Acad Sci U S A (1990) 4.11
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev (1995) 4.11
Stat3 activation is required for cellular transformation by v-src. Mol Cell Biol (1998) 4.09
A transcriptional hierarchy involved in mammalian cell-type specification. Nature (1992) 4.08
Biogenesis of mRNA: genetic regulation in mammalian cells. Science (1973) 4.01
Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev (1991) 4.01
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell (1991) 3.98
Regulation of the cyclin E gene by transcription factor E2F1. Proc Natl Acad Sci U S A (1995) 3.95
Evidence that all messenger RNA molecules (except histone messenger RNA) contain Poly (A) sequences and that the Poly(A) has a nuclear function. J Mol Biol (1972) 3.93
Intracellular uncoating of type 5 adenovirus deoxyribonucleic acid. J Virol (1967) 3.92
Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation. Cell (1988) 3.91
Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol (1992) 3.90
Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell (1998) 3.79
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation. Cell (1990) 3.77
Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev (1994) 3.76
The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. Proc Natl Acad Sci U S A (1992) 3.74
Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature (1993) 3.73
The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell (1994) 3.71
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor. Proc Natl Acad Sci U S A (1989) 3.67
Definition and mapping of adenovirus 2 nuclear transcription. Methods Enzymol (1980) 3.67
Production of mRNA in Chinese hamster cells: relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences. Cell (1979) 3.67
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell (1992) 3.64
Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction. J Biol Chem (1986) 3.63
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc Natl Acad Sci U S A (1996) 3.62
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol (1995) 3.55
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev (1990) 3.50
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev (1998) 3.48