PubRank

M L Gefter

Author PubWeight™ 202.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A 1980 24.21
2 Analysis of DNA polymerases II and 3 in mutants of Escherichia coli thermosensitive for DNA synthesis. Proc Natl Acad Sci U S A 1971 7.94
3 Properties and applications of monoclonal antibodies directed against determinants of they Thy-1 locus. J Immunol 1979 7.79
4 A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases. Proc Natl Acad Sci U S A 1972 5.83
5 A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells. Somatic Cell Genet 1977 5.65
6 Structure and in vitro transcription of human globin genes. Science 1980 4.65
7 Duplicate genes for tyrosine transfer RNA in Escherichia coli. J Mol Biol 1970 4.36
8 Role modifications in tyrosine transfer RNA: a modified base affecting ribosome binding. J Mol Biol 1969 4.01
9 Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. Proc Natl Acad Sci U S A 1971 3.95
10 RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proc Natl Acad Sci U S A 1979 3.75
11 The enzymatic repair of DNA. I. Formation of circular lambda-DNA. Proc Natl Acad Sci U S A 1967 3.67
12 Efficacy of a therapeutic cocaine vaccine in rodent models. Nat Med 1996 3.11
13 RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and vivo. J Mol Biol 1979 2.86
14 Bacteriophage phi 80-induced low molecular weight RNA. Arch Biochem Biophys 1972 2.71
15 Immunological self, nonself discrimination. Science 1987 2.59
16 Base substitution in an intervening sequence of a beta+-thalassemic human globin gene. Proc Natl Acad Sci U S A 1981 2.58
17 The genetic basis of antibody production: a single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse. Eur J Immunol 1983 2.51
18 Deoxyribonucleic acid synthesis in cell-free extracts. IV. Purification and catalytic properties of deoxyribonucleic acid polymerase III. J Biol Chem 1972 2.36
19 Interaction of peptide antigens and class II major histocompatibility complex antigens. Nature 1987 2.34
20 Somatic evolution of variable region structures during an immune response. Proc Natl Acad Sci U S A 1986 2.23
21 Purification and properties of the Escherichia coli deoxyribonucleic acid-unwinding protein. Effects on deoxyribonucleic acid synthesis in vitro. J Biol Chem 1974 2.22
22 DNA replication. Annu Rev Biochem 1975 2.18
23 Enzyme-catalyzed DNA unwinding: studies on Escherichia coli rep protein. Proc Natl Acad Sci U S A 1979 2.14
24 Dual expression of lambda genes in the MOPC-315 plasmacytoma. Nature 1981 2.03
25 Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice. Proc Natl Acad Sci U S A 1980 1.96
26 DNA synthesis in cell-free extracts of a DNA polymerase-defective mutant. Biochem Biophys Res Commun 1970 1.91
27 Interactions between immunogenic peptides and MHC proteins. Annu Rev Immunol 1991 1.82
28 Evolution of antibody variable region structure during the immune response. Immunol Rev 1987 1.77
29 Monoclonal antibodies to Rhizobium meliloti and surface mutants insensitive to them. J Bacteriol 1984 1.70
30 Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells. J Immunol 1983 1.69
31 Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera. Mol Immunol 1983 1.67
32 An iron-dependent modification of several transfer RNA species in Escherichia coli. J Mol Biol 1969 1.63
33 The genetic basis of antibody production: the dominant anti-arsonate idiotype response of the strain A mouse. Eur J Immunol 1982 1.60
34 Influence of clonal selection on the expression of immunoglobulin variable region genes. Science 1984 1.57
35 Properties of the Escherichia coli in DNA binding (unwinding) protein: interaction with DNA polymerase and DNA. Proc Natl Acad Sci U S A 1974 1.54
36 Expression and rearrangement of homologous immunoglobulin VH genes in two mouse strains. Proc Natl Acad Sci U S A 1984 1.54
37 Properties of the Escherichia coli DNA-binding (unwinding) protein interaction with nucleolytic enzymes and DNA. J Mol Biol 1975 1.42
38 Effect of IFN-gamma on the immune response in vivo and on gene expression in vitro. Nature 1984 1.41
39 A DNA-binding protein induced by bacteriophage T7. Proc Natl Acad Sci U S A 1973 1.39
40 Mutant tyrosine transfer ribonucleic acids. J Mol Biol 1970 1.36
41 Immunological activity of covalently linked T-cell epitopes. Nature 1990 1.35
42 Murine MHC polymorphism and T cell specificities. Science 1989 1.34
43 Site-directed mutagenesis of an invariant amino acid residue at the variable-diversity segments junction of an antibody. Proc Natl Acad Sci U S A 1986 1.32
44 Isolation of hybridomas expressing a specific heavy chain variable region gene segment by using a screening technique that detects mRNA sequences in whole cell lysates. Proc Natl Acad Sci U S A 1984 1.30
45 Structural diversity among anti-p-azophenylarsonate monoclonal antibodies from A/J mice; comparison of Id- and Id+ sequences. Mol Immunol 1981 1.29
46 Synthesis of messenger RNA-like molecules in isolated myeloma nuclei. Nucleic Acids Res 1977 1.29
47 Regulation of immunoglobulin expression in mouse myeloma cells. Cold Spring Harb Symp Quant Biol 1977 1.28
48 Delta 2 -isopentenylpyrophosphate: transfer ribonucleic acid 2 -isopentenyltransferase from Escherichia coli. Purification and properties of the enzyme. J Biol Chem 1972 1.28
49 Restricted V-(D)-J junctional regions in the T cell response to lambda-repressor. Identification of residues critical for antigen recognition. J Immunol 1990 1.28
50 T lymphocyte response to bacteriophage lambda repressor cI protein. Recognition of the same peptide presented by Ia molecules of different haplotypes. J Immunol 1987 1.23
51 Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase II. J Biol Chem 1972 1.23
52 In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities. J Biol Chem 1975 1.22
53 Transcription of immunoglobulin heavy-chain sequences from the excluded allele. Nature 1981 1.21
54 Recurrent somatic mutations in mouse antibodies to p-azophenylarsonate increase affinity for hapten. J Immunol 1989 1.21
55 Gene conversion and the generation of antibody diversity. Annu Rev Biochem 1989 1.20
56 Identical peptides recognized by MHC class I- and II-restricted T cells. J Exp Med 1989 1.20
57 Two structurally distinct and independently regulated idiotypic families associated with the A/J response to azophenylarsonate. Eur J Immunol 1981 1.19
58 Rna synthesis in isolated nuclei processing of adenovirus serotype 2 late messenger rna precursors. J Mol Biol 1982 1.17
59 T cell receptor gene usage in the response to lambda repressor cI protein. An apparent bias in the usage of a V alpha gene element. J Exp Med 1988 1.17
60 The in vitro synthesis of 2'-omethylguanosine and 2-methylthio 6N (gamma,gamma, dimethylallyl) adenosine in transfer RNA of Escherichia coli. Biochem Biophys Res Commun 1969 1.16
61 Studies on the mechanism of enzymatic DNA elongation by Escherichia coli DNA polymerase II. J Mol Biol 1976 1.16
62 Role of modifications in tyrosine transfer RNA. II. Ribothymidylate-deficient tRNA. Arch Biochem Biophys 1973 1.16
63 Physical studies of the interaction between the Escherichia coli DNA binding protein and nucleic acids. Nucleic Acids Res 1975 1.13
64 Enzymatic reactions at termini of DNA. J Cell Physiol 1967 1.13
65 Single germline VH and V kappa genes encode predominating antibody variable regions elicited in strain A mice by immunization with p-azophenylarsonate. J Exp Med 1987 1.13
66 The molecular evolution of the immune response: idiotope-specific suppression indicates that B cells express germ-line-encoded V genes prior to antigenic stimulation. Eur J Immunol 1986 1.13
67 The association of various D elements with a single-immunoglobulin VH gene segment: influence on the expression of a major cross-reactive idiotype. J Immunol 1985 1.12
68 Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice. J Immunol 1988 1.08
69 Multiple expression of Ig lambda-chain encoding RNA species in murine plasmacytoma cells. J Immunol 1981 1.07
70 Transcription of mammalian genes in vitro. Gene Amplif Anal 1981 1.03
71 Immunodominance: intramolecular competition between T cell epitopes. J Immunol 1991 1.02
72 Control of immunoglobulin secretion in the murine plasmacytoma line MOPC 315. J Exp Med 1978 1.02
73 Enzyme-catalyzed DNA unwinding. Mechanism of action of helicase III. J Biol Chem 1979 1.01
74 Expression of a VHC kappa chimaeric protein in mouse myeloma cells. Nature 1984 0.98
75 Structural correlates of idiotypy in the arsonate system. Ann N Y Acad Sci 1983 0.97
76 Unique determinants associated with hybridoma proteins expressing a cross-reactive idiotype: frequency among individual immune sera. J Immunol 1980 0.97
77 Complete heavy and light chain variable region sequence of anti-arsonate monoclonal antibodies from BALB/c and A/J mice sharing the 36-60 idiotype are highly homologous. J Immunol 1984 0.95
78 T lymphocyte-mediated suppression of myeloma function in vitro. III. Regulation of antibody production in hybrid myeloma cells by T lymphocytes. J Exp Med 1980 0.95
79 Enzyme-catalyzed DNA unwinding. A DNA-dependent ATPase from E. coli. J Biol Chem 1979 0.93
80 Peripheral tolerance in T cell receptor-transgenic mice: evidence for T cell anergy. Eur J Immunol 1996 0.93
81 Pertussis toxin prevents the induction of peripheral T cell anergy and enhances the T cell response to an encephalitogenic peptide of myelin basic protein. J Immunol 1991 0.93
82 Regulation of immunoglobulin biosynthesis in the murine plasmacytoma MOPC 315. J Immunol 1978 0.92
83 Crystal structure of the antigen-binding fragment of the murine anti-arsonate monoclonal antibody 36-71 at 2.9-A resolution. Proc Natl Acad Sci U S A 1990 0.92
84 A deoxyribonucleic acid-binding protein induced by bacteriophage T7. Purification and properties of the protein. J Biol Chem 1974 0.91
85 Cytolytic activity of antigen-specific T cells with helper phenotype. J Immunol 1986 0.90
86 Parallel evolution of antibody variable regions by somatic processes: consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversion. J Exp Med 1990 0.90
87 Fine specificity of idiotope suppression in the A/J anti-azophenylarsonate response. J Exp Med 1983 0.89
88 Immunotherapy with T-cell-reactive peptides derived from allergens. Allergy 1994 0.88
89 Combinational diversity within variable regions bearing the predominant anti-p-azophenylarsonate idiotype of strain A mice. J Immunol 1985 0.88
90 Immunodominance: intermolecular competition between MHC class II molecules by covalently linked T cell epitopes. J Immunol 1992 0.88
91 Somatically mutated forms of a major anti-p-azophenylarsonate antibody variable region with drastically reduced affinity for p-azophenylarsonate. By-products of an antigen-driven immune response? J Exp Med 1987 0.87
92 Molecular limitations on variable-gene junctional diversity. J Immunol 1986 0.86
93 The generation of major and minor idiotype-bearing families of anti-p-azophenylarsonate antibodies; stochastic utilization of VH gene segments. J Immunol 1985 0.86
94 Enzyme-catalyzed DNA unwinding. The role of ATP in helicase III activity. J Biol Chem 1980 0.85
95 DNA polymerases II and 3 of Escherichia coli. Prog Nucleic Acid Res Mol Biol 1974 0.84
96 Peptide therapy for treatment of allergic diseases. Clin Immunol Immunopathol 1996 0.83
97 In vitro synthesis of transfer RNA. I. Purification of required components. J Biol Chem 1975 0.82
98 Crossing-over frequency in the Igh region of the mouse genome. Ann Immunol (Paris) 1984 0.81
99 Control of cellular and humoral immune responses by peptides containing T-cell epitopes. Cold Spring Harb Symp Quant Biol 1989 0.81
100 Genetic recombination in the alpha 2 domain of the E alpha chain yields an Ed molecule with altered T cell activation. Eur J Immunol 1990 0.80
101 Identification of mutant monoclonal antibodies with increased antigen binding. Proc Natl Acad Sci U S A 1988 0.79
102 Silencing of immunodominant epitopes by contiguous sequences in complex synthetic peptides. Cell Immunol 1992 0.78
103 The molecular evolution of the immune response. Immunol Today 1985 0.78
104 Analysis of immune response at the molecular level. Pharmacol Rev 1982 0.78
105 Functional and biochemical characterization of a secreted I-J(+) suppressor factor that binds to immunoglobulin. J Exp Med 1986 0.78
106 Studies on synthesis and modification of transfer RNA. Cancer Res 1971 0.78
107 Cell-free synthesis of SU + 3 tyrosyl transfer RNA: characterization of the 4S product. Arch Biochem Biophys 1973 0.78
108 Deoxyribonucleic acid polymerase 3 (Escherichia coli K12). Methods Enzymol 1974 0.77
109 Analysis of the anti-azobenzenearsonate response at the molecular level. Ann Immunol (Paris) 1984 0.75
110 Comparison of class I- and II-restricted T cell recognition of the identical peptide. Eur J Immunol 1991 0.75
111 Once-daily propranolol for hypertension. Drug Intell Clin Pharm 1984 0.75
112 Preliminary crystallographic studies of the Fab fragment of an anti-azophenylarsonate antibody. J Mol Biol 1989 0.75
113 Modulation of restricted class II T cell responses by peptides derived from self class II molecule. Eur J Immunol 1992 0.75