Published in Proc Natl Acad Sci U S A on July 01, 1980
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc Natl Acad Sci U S A (1982) 20.55
Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci U S A (1981) 13.67
Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen. Proc Natl Acad Sci U S A (1980) 10.22
DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2. Proc Natl Acad Sci U S A (1981) 9.08
Specific 5' flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene. Proc Natl Acad Sci U S A (1981) 7.40
Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters. Mol Cell Biol (1981) 7.12
Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay. Proc Natl Acad Sci U S A (1985) 6.94
Analysis of adenovirus transforming proteins from early regions 1A and 1B with antisera to inducible fusion antigens produced in Escherichia coli. J Virol (1984) 6.73
Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res (1981) 6.63
The construction of cosmid libraries which can be used to transform eukaryotic cells. Nucleic Acids Res (1982) 5.66
Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific trans-acting components. J Virol (1985) 5.47
Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene. Mol Cell Biol (1987) 5.05
Promoter-regulatory region of the major immediate early gene of human cytomegalovirus. Proc Natl Acad Sci U S A (1984) 5.04
Structure of the promoter for chicken alpha 2 type I collagen gene. Proc Natl Acad Sci U S A (1981) 4.89
Splicing of adenovirus RNA in a cell-free transcription system. Proc Natl Acad Sci U S A (1983) 4.69
A novel method for site-directed mutagenesis: its application to an eukaryotic tRNAPro gene promoter. EMBO J (1982) 4.67
Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter. Proc Natl Acad Sci U S A (1982) 4.30
Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor. EMBO J (1984) 4.28
Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene. Proc Natl Acad Sci U S A (1985) 4.08
Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene. Proc Natl Acad Sci U S A (1985) 3.91
Fractionation and reconstitution of factors required for accurate transcription of mammalian ribosomal RNA genes: identification of a species-dependent initiation factor. Nucleic Acids Res (1982) 3.87
Alpha 4, the major regulatory protein of herpes simplex virus type 1, is stably and specifically associated with promoter-regulatory domains of alpha genes and of selected other viral genes. Proc Natl Acad Sci U S A (1986) 3.64
Specific transcription of mouse ribosomal DNA in a cell-free system that mimics control in vivo. Proc Natl Acad Sci U S A (1981) 3.57
Epstein-Barr virus gene expression in P3HR1-superinfected Raji cells. J Virol (1987) 3.56
The genome of minute virus of mice, an autonomous parvovirus, encodes two overlapping transcription units. Nucleic Acids Res (1983) 3.48
A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro. EMBO J (1987) 3.45
Synthesis of hepatitis B surface antigen in mammalian cells: expression of the entire gene and the coding region. J Virol (1983) 3.24
A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs. Proc Natl Acad Sci U S A (1989) 3.23
In vitro assembly of U1 snRNPs. EMBO J (1987) 3.18
DNA end-joining catalyzed by human cell-free extracts. Proc Natl Acad Sci U S A (1998) 3.11
Transcription occurs at a nucleoskeleton. EMBO J (1985) 3.07
Delimitation of far upstream sequences required for maximal in vitro transcription of an H2A histone gene. Proc Natl Acad Sci U S A (1982) 2.90
Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter. EMBO J (1985) 2.83
Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes. EMBO J (1983) 2.81
Transcription of hepatitis B virus by RNA polymerase II. Mol Cell Biol (1983) 2.81
Transcription and DNA sequence of the BamHI L fragment of B95-8 Epstein-Barr virus. EMBO J (1984) 2.77
Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors. EMBO J (1985) 2.70
Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence. J Virol (1988) 2.67
Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I. Mol Cell Biol (1985) 2.65
Sequences controlling in vitro transcription of SV40 promoters. EMBO J (1983) 2.65
Low molecular weight RNAs transcribed in vitro by RNA polymerase III from Alu-type dispersed repeats in Chinese hamster DNA are also found in vivo. Proc Natl Acad Sci U S A (1981) 2.60
Control region for adenovirus VA RNA transcription. Proc Natl Acad Sci U S A (1981) 2.56
Generation of single-nucleotide repair patches following excision of uracil residues from DNA. Mol Cell Biol (1992) 2.53
Species-specific rDNA transcription is due to promoter-specific binding factors. Mol Cell Biol (1984) 2.51
Is actin a transcription initiation factor for RNA polymerase B? EMBO J (1984) 2.49
Role of the mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II. Mol Cell Biol (1991) 2.45
Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer. Proc Natl Acad Sci U S A (1984) 2.44
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients. Proc Natl Acad Sci U S A (1997) 2.44
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs. EMBO J (1991) 2.38
Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs. J Virol (1989) 2.38
RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon. Mol Cell Biol (1985) 2.35
Inducible binding of a factor to the c-fos regulatory region. Proc Natl Acad Sci U S A (1987) 2.33
Construction of a modular dihydrofolate reductase cDNA gene: analysis of signals utilized for efficient expression. Mol Cell Biol (1982) 2.33
Sequences at the capped 5'-ends of polyoma virus late region mRNAs: an example of extreme terminal heterogeneity. Nucleic Acids Res (1981) 2.32
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor. Nucleic Acids Res (1984) 2.31
A T to A base substitution and small deletions in the conalbumin TATA box drastically decrease specific in vitro transcription. Nucleic Acids Res (1981) 2.31
The small subunit of transcription factor IIF recruits RNA polymerase II into the preinitiation complex. Proc Natl Acad Sci U S A (1991) 2.29
Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo. J Clin Invest (1991) 2.28
Primary processing of mammalian rRNA involves two adjacent cleavages and is not species specific. Mol Cell Biol (1987) 2.28
DNA sequence requirements for the accurate transcription of a protein-coding plastid gene in a plastid in vitro system from mustard (Sinapis alba L.). EMBO J (1984) 2.26
Purification and characterization of human DNA damage checkpoint Rad complexes. Proc Natl Acad Sci U S A (2001) 2.24
A complex control region of the mouse rRNA gene directs accurate initiation by RNA polymerase I. Mol Cell Biol (1985) 2.24
Determination of the promoter region of mouse ribosomal RNA gene by an in vitro transcription system. Proc Natl Acad Sci U S A (1984) 2.18
Analysis of transcription of the human Alu family ubiquitous repeating element by eukaryotic RNA polymerase III. Nucleic Acids Res (1981) 2.18
Substrate specificity of the dsRNA unwinding/modifying activity. EMBO J (1991) 2.18
Identification of a RNA polymerase II initiation site in the long terminal repeat of Moloney murine leukemia viral DNA. Proc Natl Acad Sci U S A (1981) 2.16
Derepression of a novel class of vaccinia virus genes upon DNA replication. EMBO J (1988) 2.13
Accurate transcription of truncated ribosomal DNA templates in a Drosophila cell-free system. Proc Natl Acad Sci U S A (1982) 2.12
RNA encoded by the IR1-U2 region of Epstein-Barr virus DNA in latently infected, growth-transformed cells. J Virol (1983) 2.12
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease. Proc Natl Acad Sci U S A (1994) 2.12
Identification of the in vivo and in vitro origin of transcription in human rDNA. Nucleic Acids Res (1982) 2.11
Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1987) 2.10
Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis. Mol Cell Biol (1986) 2.09
Adenovirus VA RNAI: a positive regulator of mRNA translation. Mol Cell Biol (1984) 2.09
Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene. Proc Natl Acad Sci U S A (1996) 2.09
Simian virus 40 major late promoter: a novel tripartite structure that includes intragenic sequences. Mol Cell Biol (1988) 2.09
Herpes simplex virus immediate early infected-cell polypeptide 4 binds to DNA and promotes transcription. Proc Natl Acad Sci U S A (1986) 2.07
Transcription of vaccinia virus early genes by a template-dependent soluble extract of purified virions. J Virol (1985) 2.05
Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products. Nucleic Acids Res (1985) 2.04
Factors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex. Mol Cell Biol (1986) 2.04
Cell cycle-dependent regulation of RNA polymerase I transcription: the nucleolar transcription factor UBF is inactive in mitosis and early G1. Proc Natl Acad Sci U S A (1999) 2.04
Effect of the 21-bp repeat upstream element on in vitro transcription from the early and late SV40 promoters. EMBO J (1984) 2.03
Transcription of minute virus of mice, an autonomous parvovirus, may be regulated by attenuation. J Virol (1984) 2.02
Tissue-specific expression of the human growth hormone gene is conferred in part by the binding of a specific trans-acting factor. EMBO J (1987) 2.02
Mitotic silencing of human rRNA synthesis: inactivation of the promoter selectivity factor SL1 by cdc2/cyclin B-mediated phosphorylation. EMBO J (1998) 2.01
In vitro transcription of a cloned mouse ribosomal RNA gene. Nucleic Acids Res (1981) 2.01
Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins. Proc Natl Acad Sci U S A (1994) 2.00
Multiple 5'-flanking regions of the human alpha-skeletal actin gene synergistically modulate muscle-specific expression. Mol Cell Biol (1987) 2.00
Isolation and characterization of the gene coding for cytosolic phosphoenolpyruvate carboxykinase (GTP) from the rat. Proc Natl Acad Sci U S A (1983) 1.99
Homologous upstream sequences near Epstein-Barr virus promoters. Proc Natl Acad Sci U S A (1983) 1.98
The mouse immunoglobulin heavy-chain enhancer: effect on transcription in vitro and binding of proteins present in HeLa and lymphoid B cell extracts. EMBO J (1986) 1.95
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts. Proc Natl Acad Sci U S A (1994) 1.94
Purification of a factor specific for the upstream element of the adenovirus-2 major late promoter. EMBO J (1986) 1.94
Simian virus 40 major late promoter: an upstream DNA sequence required for efficient in vitro transcription. Mol Cell Biol (1984) 1.94
An in vitro RNA polymerase III system from S. cerevisiae: effects of deletions and point mutations upon SUP4 gene transcription. Nucleic Acids Res (1982) 1.93
The adenovirus major late promoter TATA box and initiation site are both necessary for transcription in vitro. Nucleic Acids Res (1984) 1.91
Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A (1977) 41.76
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98
Rat insulin genes: construction of plasmids containing the coding sequences. Science (1977) 17.05
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit. Cell (1978) 9.60
Mammalian deoxyribonucleic acid-dependent ribonucleic acid polymerases. I. Purification and properties of an -amanitin-sensitive ribonucleic acid polymerase and stimulatory factors from HeLa and KB cells. J Biol Chem (1973) 8.86
Amount of viral DNA in the genome of cells transformed by adenovirus type 2. J Mol Biol (1973) 8.28
Two adenovirus mRNAs have a common 5' terminal leader sequence encoded at least 10 kb upstream from their main coding regions. Cell (1977) 6.72
The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA. Cell (1980) 5.80
The initiation sites for RNA transcription in Ad2 DNA. Cell (1977) 4.76
Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome. J Mol Biol (1978) 4.30
The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: mapping by effects of ultraviolet irradiation. Cell (1977) 4.13
Isolation and partial characterization of the multiple forms of deoxyribonucleic acid-dependent ribonucleic acid polymerase in the mouse myeloma, MOPC 315. J Biol Chem (1974) 3.84
RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proc Natl Acad Sci U S A (1979) 3.75
One predominant 5'-undecanucleotide in adenovirus 2 late messenger RNAs. Cell (1977) 3.30
Early Ad-2 transcription units: only promoter-proximal RNA continues to be made in the presence of DRB. Virology (1979) 3.06
RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and vivo. J Mol Biol (1979) 2.86
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis. Biochemistry (1973) 43.61
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell (2001) 25.86
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. I. Structure of F-prime factors. J Mol Biol (1972) 19.88
Spliced early mRNAs of simian virus 40. Proc Natl Acad Sci U S A (1978) 18.67
Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature (1986) 14.34
Spliced segments at the 5' terminus of adenovirus 2 late mRNA. Proc Natl Acad Sci U S A (1977) 14.34
The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell (1999) 13.48
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
Specific interference by ingested dsRNA. Nature (1998) 11.82
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors. J Mol Biol (1973) 11.40
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene (2001) 11.09
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell (1985) 10.06
On the role of RNA amplification in dsRNA-triggered gene silencing. Cell (2001) 9.78
DNA transformation. Methods Cell Biol (1995) 9.27
Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2. Proc Natl Acad Sci U S A (1981) 9.08
Recognition of cap structure in splicing in vitro of mRNA precursors. Cell (1984) 8.67
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (1986) 8.64
Speculations on RNA splicing. Cell (1981) 8.28
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs. Cell (1986) 8.06
Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA. Cell (1988) 8.00
Analysis of DNA polymerases II and 3 in mutants of Escherichia coli thermosensitive for DNA synthesis. Proc Natl Acad Sci U S A (1971) 7.94
Properties and applications of monoclonal antibodies directed against determinants of they Thy-1 locus. J Immunol (1979) 7.79
Cleavage of adenovirus type 2 DNA into six unique fragments by endonuclease R-RI. Proc Natl Acad Sci U S A (1973) 7.75
Splicing of messenger RNA precursors. Science (1987) 7.61
Transcription of Simian virus 40. I. Separation of the strands of SV40 DNA and hybridization of the separated strands to RNA extracted from lytically infected and transformed cells. J Mol Biol (1972) 7.49
A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Mol Cell Biol (1986) 7.49
Mechanism and regulation of mRNA polyadenylation. Genes Dev (1997) 7.48
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes. Cell (1987) 7.44
Regulation by HIV Rev depends upon recognition of splice sites. Cell (1989) 7.13
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci U S A (2001) 7.12
In vitro transcription of adenovirus. J Virol (1981) 7.06
Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors. Nature (1994) 6.97
A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell (1985) 6.27
Evolutionary fates and origins of U12-type introns. Mol Cell (1998) 6.25
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev (1988) 6.23
RNA polymerase II and the integration of nuclear events. Genes Dev (2000) 6.16
Distinct requirements for somatic and germline expression of a generally expressed Caernorhabditis elegans gene. Genetics (1997) 6.08
A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell (1990) 5.92
Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites. Science (1992) 5.87
A DNA-unwinding protein isolated from Escherichia coli: its interaction with DNA and with DNA polymerases. Proc Natl Acad Sci U S A (1972) 5.83
Human CCAAT-binding proteins have heterologous subunits. Cell (1988) 5.81
A high-efficiency HeLa cell nuclear transcription extract. DNA (1988) 5.81
Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell (1991) 5.72
A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells. Somatic Cell Genet (1977) 5.65
Transcriptional repression of eukaryotic promoters. Cell (1989) 5.60
Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. Science (1986) 5.52
Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell (1985) 5.27
Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference. Mol Cell (2000) 5.18
Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors. Science (1984) 5.11
Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene. Mol Cell Biol (1987) 5.05
The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation. Cell (1996) 4.93
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Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter. Proc Natl Acad Sci U S A (1988) 4.83
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Separation and characterization of factors mediating accurate transcription by RNA polymerase II. J Biol Chem (1982) 4.71
On the origin of RNA splicing and introns. Cell (1985) 4.70
Sequence heterogeneity in closed simian virus 40 deoxyribonucleic acid. J Virol (1972) 4.69
Splicing of adenovirus RNA in a cell-free transcription system. Proc Natl Acad Sci U S A (1983) 4.69
The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities. EMBO J (1995) 4.66
The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. EMBO J (1996) 4.65
Structure and in vitro transcription of human globin genes. Science (1980) 4.65
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Proc Natl Acad Sci U S A (1998) 4.63
Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes Dev (1989) 4.53
Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein. Cell (1983) 4.42
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element. Nature (1982) 4.42
Duplicate genes for tyrosine transfer RNA in Escherichia coli. J Mol Biol (1970) 4.36
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature (2000) 4.36
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HIV-1 Tat protein promotes formation of more-processive elongation complexes. EMBO J (1991) 4.18
Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans. Genetics (1993) 4.18
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. Genes Dev (1988) 4.14
In vitro transcription: whole-cell extract. Methods Enzymol (1983) 4.07
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Affinity chromatography of splicing complexes: U2, U5, and U4 + U6 small nuclear ribonucleoprotein particles in the spliceosome. Science (1986) 4.01
Messenger RNA splicing in vitro: an excised intervening sequence and a potential intermediate. Cell (1984) 4.00
Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. Proc Natl Acad Sci U S A (1971) 3.95
Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing. Genes Dev (1989) 3.95
An improved bacteriophage lambda vector: construction of model recombinants coding for kanamycin resistance. Gene (1977) 3.94
Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature (1988) 3.91
Cleavage maps of DNA from adenovirus types 2 and 5 by restriction endonucleases EcoRI and HpaI. Cold Spring Harb Symp Quant Biol (1975) 3.87
Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing. Genes Dev (1997) 3.87
Transcription maps of adenovirus. Methods Enzymol (1980) 3.82
A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II. Genes Dev (1988) 3.80
The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell (1989) 3.77
DNA topology and a minimal set of basal factors for transcription by RNA polymerase II. Cell (1993) 3.77
RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proc Natl Acad Sci U S A (1979) 3.75