Published in Cancer on December 15, 1980
Tamoxifen as the first targeted long-term adjuvant therapy for breast cancer. Endocr Relat Cancer (2014) 0.90
Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications. Breast Cancer Res Treat (1983) 0.82
Adjuvant endocrine therapy, cytotoxic chemotherapy, and immunotherapy in stage-II breast cancer: five-year results. Breast Cancer Res Treat (1983) 0.75
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (1987) 49.88
Detection of hepatitis C viral sequences in non-A, non-B hepatitis. Lancet (1990) 8.56
Crystal structure of cyclin-dependent kinase 2. Nature (1993) 5.21
Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation. Science (1998) 4.74
Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. Virology (1991) 4.47
Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst (1993) 4.45
Psychometric scores and persistence of irritable bowel after infectious diarrhoea. Lancet (1996) 4.23
Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15. EMBO J (1992) 4.21
New insights to the MLL recombinome of acute leukemias. Leukemia (2009) 4.07
Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer Res (1977) 4.02
Cathepsin D and prognosis in breast cancer. N Engl J Med (1990) 3.43
Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts. Cell (1994) 3.42
The value of estrogen and progesterone receptors in the treatment of breast cancer. Cancer (1980) 3.34
Prediction of relapse or survival in patients with node-negative breast cancer by DNA flow cytometry. N Engl J Med (1989) 3.21
Estrogen control of progesterone receptor in human breast cancer. Correlation with nuclear processing of estrogen receptor. J Biol Chem (1978) 3.05
HER-2/neu oncogene protein and prognosis in breast cancer. J Clin Oncol (1989) 2.96
A purified Drosophila septin complex forms filaments and exhibits GTPase activity. J Cell Biol (1996) 2.76
A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J Immunol (1998) 2.74
Work loads and practice patterns of general surgeons in the United States, 1995-1997: a report from the American Board of Surgery. Ann Surg (1999) 2.58
Actin dynamics in vivo. Curr Opin Cell Biol (1997) 2.58
The natural history and management of radiation induced injury of the gastrointestinal tract. Ann Surg (1969) 2.56
The MLL recombinome of acute leukemias in 2013. Leukemia (2013) 2.55
Phytoestrogen interaction with estrogen receptors in human breast cancer cells. Endocrinology (1978) 2.42
Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data. Leukemia (2007) 2.40
The optimal timing of mastectomy: low tide or high tide? Ann Intern Med (1991) 2.40
Vagus nerve stimulation therapy for partial-onset seizures: a randomized active-control trial. Neurology (1998) 2.32
BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer. Am J Hum Genet (2000) 2.31
Studies on the mechanism of steroid hormone regulation of synthesis of specific proteins. Recent Prog Horm Res (1969) 2.31
PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro. Proc Natl Acad Sci U S A (1994) 2.29
Predicting response to endocrine therapy in human breast cancer: a hypothesis. Science (1975) 2.29
Breast cancer prognostic factors: evaluation guidelines. J Natl Cancer Inst (1991) 2.29
Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen. Endocrinology (1978) 2.25
Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction. Methods (2000) 2.16
Prolactin-dependent rat mammary cancer: a model for man? Trans Assoc Am Physicians (1969) 2.15
Nucleation time: a key factor in the pathogenesis of cholesterol gallstone disease. Gastroenterology (1979) 2.15
HER-2/neu amplification predicts poor survival in node-positive breast cancer. Cancer Res (1990) 2.14
Survival from first recurrence: relative importance of prognostic factors in 1,015 breast cancer patients. J Clin Oncol (1987) 2.12
The natural history of splenic infarction. Surgery (1986) 2.11
Is "idiopathic" edema idiopathic? Lancet (1979) 2.11
Current status of estrogen and progesterone receptors in breast cancer. Cancer (1977) 2.10
Overexpression of HER-2/neu and its relationship with other prognostic factors change during the progression of in situ to invasive breast cancer. Hum Pathol (1992) 2.05
Early events in hepatitis C virus infection of chimpanzees. Proc Natl Acad Sci U S A (1990) 2.04
Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation. Am J Respir Cell Mol Biol (1997) 2.02
Processing of laminin-5 and its functional consequences: role of plasmin and tissue-type plasminogen activator. J Cell Biol (1998) 2.00
Ploidy, proliferative activity and prognosis. DNA flow cytometry of solid tumors. Cancer (1990) 2.00
Biological and clinical implications of heat shock protein 27,000 (Hsp27): a review. J Natl Cancer Inst (1993) 1.99
Hormone receptors: their role in predicting prognosis and response to endocrine therapy. Semin Oncol (1978) 1.99
Scatchard plots: common errors in correction and interpretation. Steroids (1975) 1.98
Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications. J Natl Cancer Inst (1993) 1.95
Monoclonal antibodies against three major glycoproteins of varicella-zoster virus. Infect Immun (1983) 1.95
Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res (1991) 1.92
The annual injury of 15,000,000 children: a limited study of childhood accidental injury and death. J Trauma (1966) 1.89
Steroid receptor analyses of nine human breast cancer cell lines. Cancer Res (1978) 1.87
Breast cancer survival and perioperative blood transfusion. Surgery (1989) 1.85
Correlations between estrogen receptor, progesterone receptor, and patient characteristics in human breast cancer. J Clin Oncol (1984) 1.84
Intermediate filaments and the initiation of desmosome assembly. J Cell Biol (1985) 1.84
Dynamic aspects of the supramolecular organization of intermediate filament networks in cultured epidermal cells. Cell Motil (1982) 1.83
The alpha3 laminin subunit, alpha6beta4 and alpha3beta1 integrin coordinately regulate wound healing in cultured epithelial cells and in the skin. J Cell Sci (1999) 1.82
Trauma is a recurrent disease. Surgery (1993) 1.82
Progesterone receptors as a prognostic factor in Stage II breast cancer. N Engl J Med (1983) 1.79
Prognostic significance of progesterone receptor levels in estrogen receptor-positive patients with metastatic breast cancer treated with tamoxifen: results of a prospective Southwest Oncology Group study. J Clin Oncol (1992) 1.76
DNA flow cytometry and prognostic factors in 1331 frozen breast cancer specimens. Cancer (1988) 1.75
The relationship between intermediate filaments and microfilaments before and during the formation of desmosomes and adherens-type junctions in mouse epidermal keratinocytes. J Cell Biol (1987) 1.74
Why do so many prognostic factors fail to pan out? Breast Cancer Res Treat (1992) 1.74
MCF-7; a human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors. Steroids (1975) 1.72
Pleural empyema in children. Ann Thorac Surg (1970) 1.71
Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB J (1996) 1.70
The matrix secreted by 804G cells contains laminin-related components that participate in hemidesmosome assembly in vitro. J Cell Sci (1993) 1.70
Interaction of BP180 (type XVII collagen) and alpha6 integrin is necessary for stabilization of hemidesmosome structure. J Invest Dermatol (1998) 1.69
Current status of estrogen receptors in human breast cancer. Cancer (1975) 1.66
Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing. J Biol Chem (1978) 1.66
Partial mastectomy for carcinoma of the breast. Surg Gynecol Obstet (1973) 1.63
Evaluation of enzyme-linked immunoassay for serological diagnosis of cysticercosis. J Clin Microbiol (1995) 1.61
Botulinum toxin--a possible new treatment for axillary hyperhidrosis. Clin Exp Dermatol (1996) 1.60
Rapid evolution and selection inferred from the transcriptomes of sympatric crater lake cichlid fishes. Mol Ecol (2010) 1.55
HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma. J Clin Oncol (1992) 1.55
Estrogen receptor, progesterone receptor, and HER-2/neu protein in breast cancers from pregnant patients. Cancer (1993) 1.54
Monoclonal antibody identification and characterization of a Mr 43,000 membrane glycoprotein associated with human breast cancer. Cancer Res (1986) 1.53
Multiple estrogen receptor assays in human breast cancer. Cancer Res (1983) 1.52
Improved sensitivity in the measurement of estrogen receptor in human breast cancer. J Clin Endocrinol Metab (1973) 1.51
The MLL recombinome of acute leukemias. Leukemia (2006) 1.51
Insulin-like growth factor-I receptors are overexpressed and predict a low risk in human breast cancer. Cancer Res (1993) 1.51
Immunochemical characterization of three components of the hemidesmosome and their expression in cultured epithelial cells. J Cell Biol (1989) 1.50
Varicella-zoster virus-specific gp140: a highly immunogenic and disulfide-linked structural glycoprotein. Virology (1984) 1.49
Disappearance rates of endogenous luteinizing hormone and chorionic gonadotropin in man. J Clin Endocrinol Metab (1968) 1.48
Effect of exercise and recovery on muscle protein synthesis in human subjects. Am J Physiol (1990) 1.48
Suicidal ideation and suicide attempts among patients with panic disorder: a survey of two outpatient clinics. Am J Psychiatry (1992) 1.47
Surface relocation of alpha 6 beta 4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing. J Cell Biol (1991) 1.47
Laminin-5 and hemidesmosomes: role of the alpha 3 chain subunit in hemidesmosome stability and assembly. J Cell Sci (1996) 1.45
Cytoplasmic domain of the 180-kD bullous pemphigoid antigen, a hemidesmosomal component: molecular and cell biologic characterization. J Invest Dermatol (1992) 1.44
Adjuvant therapy of node-negative breast cancer. N Engl J Med (1989) 1.43
Hormones in breast cancer: update 1978. Metabolism (1978) 1.43
Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer. Am J Hum Genet (1997) 1.42