PubRank

S W Cushman

Author PubWeight™ 139.65‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane. J Biol Chem 1980 6.80
2 Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity. J Biol Chem 1981 3.28
3 Studies of human adipose tissue. Adipose cell size and number in nonobese and obese patients. J Clin Invest 1973 3.21
4 Insulin-stimulated translocation of glucose transporters in the isolated rat adipose cells: characterization of subcellular fractions. Biochim Biophys Acta 1983 2.88
5 Hormonal regulation of mammalian glucose transport. Annu Rev Biochem 1986 2.84
6 Cell surface labeling of glucose transporter isoform GLUT4 by bis-mannose photolabel. Correlation with stimulation of glucose transport in rat adipose cells by insulin and phorbol ester. J Biol Chem 1990 2.84
7 Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis. Diabetologia 2007 2.71
8 Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action. J Biol Chem 1993 2.41
9 Mechanism of insulin action on glucose transport in the isolated rat adipose cell. Enhancement of the number of functional transport systems. J Biol Chem 1978 1.99
10 Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. J Clin Invest 1989 1.89
11 Analysis of GLUT4 distribution in whole skeletal muscle fibers: identification of distinct storage compartments that are recruited by insulin and muscle contractions. J Cell Biol 1998 1.83
12 Glucose deprivation and hexose transporter polypeptides of murine fibroblasts. J Biol Chem 1986 1.81
13 Inflammation in subcutaneous adipose tissue: relationship to adipose cell size. Diabetologia 2009 1.70
14 Determinations of adipose cell size and number in suspensions of isolated rat and human adipose cells. J Lipid Res 1978 1.67
15 Insulin-stimulated GLUT4 glucose transporter recycling. A problem in membrane protein subcellular trafficking through multiple pools. J Biol Chem 1994 1.67
16 Structure-function relationships in the adipose cell. I. Ultrastructure of the isolated adipose cell. J Cell Biol 1970 1.58
17 Expression of auxilin or AP180 inhibits endocytosis by mislocalizing clathrin: evidence for formation of nascent pits containing AP1 or AP2 but not clathrin. J Cell Sci 2001 1.57
18 Mechanism of insulin-resistant glucose transport activity in the enlarged adipose cell of the aged, obese rat. J Clin Invest 1982 1.51
19 Potential mechanism of the stimulatory action of insulin on insulin-like growth factor II binding to the isolated rat adipose cell. Apparent redistribution of receptors cycling between a large intracellular pool and the plasma membrane. J Biol Chem 1984 1.51
20 Demonstration of insulin-responsive trafficking of GLUT4 and vpTR in fibroblasts. J Cell Sci 2000 1.48
21 A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems. J Clin Invest 1981 1.47
22 Detection of the rat adipose cell glucose transporter with antibody against the human red cell glucose transporter. Biochem Biophys Res Commun 1982 1.46
23 Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte. cAMP-independent effects of lipolytic and antilipolytic agents. J Biol Chem 1987 1.42
24 Pioglitazone increases the proportion of small cells in human abdominal subcutaneous adipose tissue. Obesity (Silver Spring) 2009 1.39
25 Development of an intracellular pool of glucose transporters in 3T3-L1 cells. J Biol Chem 1992 1.37
26 Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells. Mol Cell Biol 1995 1.36
27 Divergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. Alterations in both glucose transporter number and intrinsic activity. J Clin Invest 1988 1.32
28 Insulin-stimulated glucose transport in rat adipose cells. Modulation of transporter intrinsic activity by isoproterenol and adenosine. J Biol Chem 1986 1.32
29 Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin. J Biol Chem 1998 1.30
30 Activity and phosphorylation state of glucose transporters in plasma membranes from insulin-, isoproterenol-, and phorbol ester-treated rat adipose cells. J Biol Chem 1987 1.29
31 Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4. Proc Natl Acad Sci U S A 1994 1.29
32 Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression. J Clin Invest 1991 1.28
33 Mechanism for markedly hyperresponsive insulin-stimulated glucose transport activity in adipose cells from insulin-treated streptozotocin diabetic rats. Evidence for increased glucose transporter intrinsic activity. J Biol Chem 1987 1.27
34 Qualitative and quantitative comparison of glucose transport activity and glucose transporter concentration in plasma membranes from basal and insulin-stimulated rat adipose cells. Biochem J 1988 1.27
35 Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells. J Biol Chem 1994 1.26
36 Immunocytochemical evidence that GLUT4 resides in a specialized translocation post-endosomal VAMP2-positive compartment in rat adipose cells in the absence of insulin. J Histochem Cytochem 1997 1.24
37 Insulin stimulates both leptin secretion and production by rat white adipose tissue. Endocrinology 1997 1.22
38 Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine. Biochem J 1992 1.21
39 Insulin-regulated trafficking of dual-labeled glucose transporter 4 in primary rat adipose cells. Biochem Biophys Res Commun 2001 1.19
40 Immunoelectron microscopic evidence that GLUT4 translocation explains the stimulation of glucose transport in isolated rat white adipose cells. J Cell Sci 2000 1.18
41 Structure-function relationships in the adipose cell. II. Pinocytosis and factors influencing its activity in the isolated adipose cell. J Cell Biol 1970 1.14
42 Transfection of DNA into isolated rat adipose cells by electroporation: evaluation of promoter activity in transfected adipose cells which are highly responsive to insulin after one day in culture. Biochem Biophys Res Commun 1993 1.14
43 A possible mechanism of insulin resistance in the rat adipose cell with high-fat/low-carbohydrate feeding. Depletion of intracellular glucose transport systems. Diabetes 1982 1.13
44 Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women. Diabetologia 2008 1.12
45 Role of insulin receptor substrate-1 and pp60 in the regulation of insulin-induced glucose transport and GLUT4 translocation in primary adipocytes. J Biol Chem 1997 1.11
46 GLUT4 overexpression in db/db mice dose-dependently ameliorates diabetes but is not a lifelong cure. Diabetes 2001 1.09
47 Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein. Biochem J 1996 1.09
48 Targeting of GLUT6 (formerly GLUT9) and GLUT8 in rat adipose cells. Biochem J 2001 1.08
49 Biochemical and functional heterogeneity of rat adipocyte glucose transporters. J Biol Chem 1986 1.08
50 Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin-responsive cells. Bioessays 1994 1.08
51 Insulin stimulation of glucose transport activity in rat skeletal muscle: increase in cell surface GLUT4 as assessed by photolabelling. Biochem J 1994 1.08
52 Calorie restriction increases cell surface GLUT-4 in insulin-stimulated skeletal muscle. Am J Physiol 1998 1.05
53 Morphological effects of wortmannin on the endosomal system and GLUT4-containing compartments in rat adipose cells. J Cell Sci 1997 1.05
54 Vp165 and GLUT4 share similar vesicle pools along their trafficking pathways in rat adipose cells. FEBS Lett 1997 1.04
55 Insulinomimetic effect on glucose transport by epidermal growth factor when combined with a major histocompatibility complex class I-derived peptide. J Biol Chem 1993 1.04
56 Regulation of glucose utilization in adipose cells and muscle after long-term experimental hyperinsulinemia in rats. J Clin Invest 1985 1.03
57 Subcellular translocation of glucose transporters: role in insulin action and its perturbation in altered metabolic states. Diabetes Metab Rev 1985 1.02
58 Subcutaneous adipose cell size and distribution: relationship to insulin resistance and body fat. Obesity (Silver Spring) 2013 1.00
59 Cell-associated fatty acid levels and energy-requiring processes in mouse adipocytes. Am J Physiol 1974 1.00
60 Dexamethasone inhibits insulin-stimulated recruitment of GLUT4 to the cell surface in rat skeletal muscle. Metabolism 1998 1.00
61 Regulation of glucose transporter-specific mRNA levels in rat adipose cells with fasting and refeeding. Implications for in vivo control of glucose transporter number. J Clin Invest 1989 0.99
62 Immunohistochemical localization of facilitated-diffusion glucose transporters in rat pancreatic islets. Tissue Cell 1996 0.99
63 Glucose transport and GLUT4 protein distribution in skeletal muscle of GLUT4 transgenic mice. Biochem J 1996 0.98
64 Glucose transport and cell surface GLUT-4 protein in skeletal muscle of the obese Zucker rat. Am J Physiol 1996 0.98
65 Glucose metabolism and the response to insulin by human adipose tissue in spontaneous and experimental obesity. Effects of dietary composition and adipose cell size. J Clin Invest 1974 0.97
66 Phosphorylation state of the GLUT4 isoform of the glucose transporter in subfractions of the rat adipose cell: effects of insulin, adenosine, and isoproterenol. Proc Natl Acad Sci U S A 1991 0.96
67 Effects of noradrenaline on the cell-surface glucose transporters in cultured brown adipocytes: novel mechanism for selective activation of GLUT1 glucose transporters. Biochem J 1998 0.96
68 Insulin-induced internalization of the insulin receptor in the isolated rat adipose cell. Detection of the internalized 138-kilodalton receptor subunit using a photoaffinity 125I-insulin. J Biol Chem 1983 0.95
69 Intracellular glucose concentration in small and large rat adipose cells. Am J Physiol 1980 0.95
70 Glucose transport in isolated rat adipocytes with measurements of L-arabinose uptake. Am J Physiol 1978 0.94
71 Inhibition of internalization of glucose transporters and IGF-II receptors. Mechanism of action of MHC class I-derived peptides which augment the insulin response in rat adipose cells. J Biol Chem 1993 0.94
72 Structure-function relationships in the adipose cell. 3. Effects of bovine serum albumin on the metabolism of glucose and the release of nonesterified fatty acids and glycerol by the isolated adipose cell. J Cell Biol 1970 0.93
73 Exercise training reverses insulin resistance in muscle by enhanced recruitment of GLUT-4 to the cell surface. Am J Physiol 1997 0.93
74 Overexpression of the glucose transporter GLUT4 in adipose cells interferes with insulin-stimulated translocation. FEBS Lett 1999 0.93
75 Mechanism for enhanced glucose transport response to insulin in adipose cells from chronically hyperinsulinemic rats. Increased translocation of glucose transporters from an enlarged intracellular pool. J Clin Invest 1987 0.92
76 SNAP-23 participates in SNARE complex assembly in rat adipose cells. Biochem J 1999 0.92
77 Effects of dietary composition on glucose metabolism in rat adipose cells. Am J Physiol 1981 0.91
78 Identification and characterization of the rat adipocyte glucose transporter by photoaffinity crosslinking. FEBS Lett 1983 0.91
79 Role of protein kinase C in the regulation of glucose transport in the rat adipose cell. Translocation of glucose transporters without stimulation of glucose transport activity. J Biol Chem 1991 0.90
80 Proposed mechanism of insulin-resistant glucose transport in the isolated guinea pig adipocyte. Small intracellular pool of glucose transporters. J Biol Chem 1983 0.90
81 Effects of exercise training on glucose transport and cell surface GLUT-4 in isolated rat epitrochlearis muscle. Am J Physiol 1997 0.90
82 Glucose transporter localization in rat skeletal muscle. Autoradiographic study using ATB-[2-3H]BMPA photolabel. FEBS Lett 1994 0.89
83 1-[N, O-bis-(5-isoquinolinesulphonyl)-N-methyl-L-tyrosyl]-4- phenylpiperazine (KN-62), an inhibitor of calcium-dependent camodulin protein kinase II, inhibits both insulin- and hypoxia-stimulated glucose transport in skeletal muscle. Biochem J 1999 0.89
84 Characterization of the stimulatory action of insulin on insulin-like growth factor II binding to rat adipose cells. Differences in the mechanism of insulin action on insulin-like growth factor II receptors and glucose transporters. J Biol Chem 1988 0.89
85 Insulin-induced translocation of intracellular glucose transporters in the isolated rat adipose cell. Fed Proc 1984 0.88
86 Regulation of cell surface GLUT4 in skeletal muscle of transgenic mice. Biochem J 1997 0.86
87 The effects of insulin on the level and activity of the GLUT4 present in human adipose cells. Diabetologia 1995 0.86
88 Role of SNARE's in the GLUT4 translocation response to insulin in adipose cells and muscle. J Basic Clin Physiol Pharmacol 1998 0.85
89 Transient enhancement of GLUT-4 levels in rat epitrochlearis muscle after exercise training. J Appl Physiol (1985) 2000 0.85
90 Insulin-induced internalization of the insulin receptor in the isolated rat adipose cell. Detection of both major receptor subunits following their biosynthetic labeling in culture. Diabetes 1984 0.85
91 Insulin-induced subcellular redistribution of insulin-like growth factor II receptors in the rat adipose cell. Counterregulatory effects of isoproterenol, adenosine, and cAMP analogues. J Biol Chem 1988 0.83
92 Alterations in glucose metabolism and its stimulation by insulin in isolated adipose cells during the development of genetic obesity in the Zucker fatty rat. Metabolism 1978 0.83
93 Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells. Biochem Biophys Res Commun 1996 0.83
94 Hormonal regulation of glucose transport in a brown adipose cell preparation isolated from rats that shows a large response to insulin. Biochem J 1996 0.83
95 Cholera and pertussis toxins modify regulation of glucose transport activity in rat adipose cells: evidence for mediation of a cAMP-independent process by G-proteins. Cell Signal 1992 0.83
96 Mechanism of hypoxia-stimulated glucose transport in rat skeletal muscle: potential role of glycogen. Am J Physiol 1998 0.83
97 Characterisation of insulin-resistant phenotype of cultured rat primary adipose cells. Diabetologia 2007 0.82
98 Subcellular distribution and phosphorylation state of insulin receptors from insulin- and isoproterenol-treated rat adipose cells. Cell Signal 1991 0.82
99 GLUT4 trafficking in insulin-stimulated rat adipose cells: evidence that heterotrimeric GTP-binding proteins regulate the fusion of docked GLUT4-containing vesicles. Biochem J 1999 0.81
100 Adipose cell size-function relationships: insulin binding and degradation. Am J Physiol 1981 0.81
101 Mechanism of insulin's stimulatory action on glucose transport in the isolated rat adipose cell. Soc Gen Physiol Ser 1985 0.80
102 The export of major histocompatibility complex class I molecules from the endoplasmic reticulum of rat brown adipose cells is acutely stimulated by insulin. Mol Biol Cell 2001 0.79
103 Comparison of body weight and adipose tissue in male C57Bl/6J mice fed diets with and without trans fatty acids. Lipids 1994 0.79
104 Regulation of the GLUT1 glucose transporter in cultured myocytes: total number and subcellular distribution as determined by photoaffinity labelling. Biochem J 1994 0.79
105 Cell-associated nonesterified fatty acid levels and their alteration during lipolysis in the isolated mouse adipose cell. J Lipid Res 1973 0.78
106 Acute effects of cycloheximide on the translocation of glucose transporters in rat adipose cells. J Biol Chem 1989 0.78
107 Short-term exercise enhances insulin-stimulated GLUT-4 translocation and glucose transport in adipose cells. J Appl Physiol (1985) 1998 0.78
108 Insulin stimulates hormone-sensitive cyclic GMP-inhibited cyclic nucleotide phosphodiesterase in rat brown adipose cells. FEBS Lett 1995 0.77
109 Unique subcellular distribution of five annexins in resting and insulin-stimulated rat adipose cells. Biochem Biophys Res Commun 1996 0.77
110 Effects of fluorescein isothiocyanate on insulin actions in rat adipocytes. Arch Biochem Biophys 1992 0.77
111 Rab 3D in rat adipose cells and its overexpression in genetic obesity (Zucker fatty rat). Biochem J 1997 0.77
112 Integral membrane protein translocations in the mechanism of insulin action. Biochem Soc Symp 1985 0.76
113 Insulin, amino acid metabolism and lipolysis in isolated fat-cells. Biochem J 1971 0.75
114 Body composition, adipocyte size, free fatty acid concentration, and glucose tolerance in children of diabetic pregnancies. Diabetes 1986 0.75
115 Low density lipoprotein receptors in rat adipose cells: subcellular localization and regulation by insulin. J Lipid Res 1994 0.75
116 Pinocytic activity in the isolated adipose cell. Horm Metab Res 1970 0.75
117 Thyroid hormone increases the partitioning of glucose transporters to the plasma membrane in ARL 15 cells. Am J Physiol 1995 0.75
118 Cell biology of insulin's stimulatory action on glucose transport and its perturbation in altered metabolic states. Ann N Y Acad Sci 1986 0.75
119 Hormonal regulation of glucose transport in rat adipose cells. Biochem Soc Trans 1990 0.75
120 Do adipocytes contain high affinity sulfonylurea receptors. Endocrinology 1994 0.75
121 Mechanism of insulin-resistance in the adipose cell in the aging-rat model of obesity. Biochem Soc Trans 1981 0.75
122 Absence of an early effect of glucocorticoids on nonesterified fatty acid accumulation in isolated rat thymus cells. J Steroid Biochem 1980 0.75
123 A biological activity of the A-chain of insulin and the inactivity of a synthetic analogue containing an intact intrachain disulfide bridge. Biochem Biophys Res Commun 1967 0.75