Published in Pharmacol Ther on January 01, 1981
Species differences in nucleoside transport. A study of uridine transport and nitrobenzylthioinosine binding by mammalian erythrocytes. Biochem J (1982) 1.26
Adenosinergic modulation of respiratory neurones and hypoxic responses in the anaesthetized cat. J Physiol (1995) 1.11
Adenosine formation and release from neonatal-rat heart cells in culture. Biochem J (1985) 1.08
The kinetics of dissociation of the inhibitor of nucleoside transport, nitrobenzylthioinosine, from the high-affinity binding sites of cultured hamster cells. Biochem J (1983) 1.02
Nucleoside transport in human erythrocytes. A simple carrier with directional symmetry in fresh cells, but with directional asymmetry in cells from outdated blood. Biochem J (1983) 0.99
ABC transporters and their role in nucleoside and nucleotide drug resistance. Biochem Pharmacol (2012) 0.98
Combination therapy of schistosomiasis by tubercidin and nitrobenzylthioinosine 5'-monophosphate. Proc Natl Acad Sci U S A (1983) 0.94
Purification of the human erythrocyte nucleoside transporter by immunoaffinity chromatography. Biochem J (1988) 0.92
Kinetics of nitrobenzylthioinosine binding to the human erythrocyte nucleoside transporter. Biochem J (1983) 0.91
Nucleoside transport in Walker 256 rat carcinosarcoma and S49 mouse lymphoma cells. Differences in sensitivity to nitrobenzylthioinosine and thiol reagents. Biochem J (1985) 0.90
Prevention of tubercidin host toxicity by nitrobenzylthioinosine 5'-monophosphate for the treatment of schistosomiasis. Antimicrob Agents Chemother (1989) 0.89
Photoaffinity labelling of nucleoside-transport proteins in plasma membranes isolated from rat and guinea-pig liver. Biochem J (1984) 0.88
Membrane transport influences the rate of accumulation of cytosine arabinoside in human leukemia cells. J Clin Invest (1987) 0.87
Transport and metabolism of adenosine in the perfused guinea-pig placenta. J Physiol (1988) 0.83
Solubilization and reconstitution of a nucleoside-transport system from Ehrlich ascites-tumour cells. Biochem J (1989) 0.83
Modulation of the equilibrative nucleoside transporter by inhibitors of DNA synthesis. Br J Cancer (1995) 0.82
Proteolytic cleavage of [3H]nitrobenzylthioinosine-labelled nucleoside transporter in human erythrocytes. Biochem J (1985) 0.80
Dipyridamole potentiates the in vitro activity of MTA (LY231514) by inhibition of thymidine transport. Br J Cancer (2000) 0.80
Trans-stimulation and trans-inhibition of uridine efflux from human erythrocytes by permeant nucleosides. Biochem J (1986) 0.79
[3H]dipyridamole binding to nucleoside transporters from guinea-pig and rat lung. Biochem J (1986) 0.78
Differential uptake of [3H]guanosine by nucleoside transporter subtypes in Ehrlich ascites tumour cells. Biochem J (1992) 0.76
Residual nitrobenzylthioinosine-resistant nucleoside transport in a transport mutant (AE1) of S49 murine T-lymphoma cells. Mol Cell Biol (1987) 0.75
Modulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnancies. J Physiol (2001) 0.75
Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. Nat Med (1997) 2.61
Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines. Cancer Res (1998) 2.32
A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine. Cancer Res (1974) 2.14
Mediated transport of nucleosides in human erythrocytes. Specific binding of the inhibitor nitrobenzylthioinosine to nucleoside transport sites in the erythrocyte membrane. Biochim Biophys Acta (1974) 2.00
Nucleoside transporters: molecular biology and implications for therapeutic development. Mol Med Today (1999) 1.58
Inhibitors of nucleoside transport. A structure-activity study using human erythrocytes. J Med Chem (1975) 1.52
Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins. Xenobiotica (2008) 1.48
Nucleoside transport. I. A mediated process in human erythrocytes. Can J Biochem (1971) 1.45
Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). J Biol Chem (2000) 1.44
Specificity of adenosine uptake into the heart and inhibition by dipyridamole. Eur J Pharmacol (1970) 1.42
Emerging transporters of clinical importance: an update from the International Transporter Consortium. Clin Pharmacol Ther (2013) 1.42
The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. Mol Membr Biol (2001) 1.40
Nitrobenzylthionionosine binding sites in the erythrocyte membrane. Biochim Biophys Acta (1976) 1.39
Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants. J Biol Chem (1972) 1.38
Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein. J Biol Chem (1994) 1.35
A common basis for inhibition of nucleoside transport by dipyridamole and nitrobenzylthioinosine? Mol Pharmacol (1980) 1.29
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters. J Natl Cancer Inst (1999) 1.27
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy. Biochem J (2000) 1.26
Species differences in nucleoside transport. A study of uridine transport and nitrobenzylthioinosine binding by mammalian erythrocytes. Biochem J (1982) 1.26
Nucleoside transport. II. Inhibition by p-nitrobenzylthioguanosine and related compounds. Can J Biochem (1971) 1.25
Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues. J Biol Chem (1997) 1.25
Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs. J Biol Chem (2001) 1.24
Urapidil and some analogues with hypotensive properties show high affinities for 5-hydroxytryptamine (5-HT) binding sites of the 5-HT1A subtype and for alpha 1-adrenoceptor binding sites. Naunyn Schmiedebergs Arch Pharmacol (1987) 1.23
Inhibition of adenosine uptake in human erythrocytes by adenosine-5'-carboxamides, xylosyladenine, dipyridamole, hexobendine, and p-nitrobenzylthioguanosine. Biochem Pharmacol (1978) 1.18
Species differences in action and elimination of adenosine after dipyridamole and hexobendine. Eur J Pharmacol (1971) 1.17
Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta. Biochem J (1997) 1.17
Transport of nucleosides. Ann N Y Acad Sci (1975) 1.17
Photoaffinity labeling of the human erythrocyte nucleoside transporter by N6-(p-Azidobenzyl)adenosine and nitrobenzylthioinosine. Evidence that the transporter is a band 4.5 polypeptide. J Biol Chem (1983) 1.15
Cytosine arabinoside influx and nucleoside transport sites in acute leukemia. J Clin Invest (1982) 1.15
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1). Am J Physiol (1997) 1.15
Absence of binding sites for the transport inhibitor nitrobenzylthioinosine on nucleoside transport-deficient mouse lymphoma cells. Biochim Biophys Acta (1981) 1.14
Inhibitors of nucleoside and nucleotide metabolism. Cancer Chemother Rep 2 (1972) 1.12
Binding of the nucleoside transport inhibitor 4-nitrobenzylthioinosine to erythrocyte membranes. Can J Biochem (1973) 1.11
Nucleoside transport and its significance for anticancer drug resistance. Drug Resist Updat (1998) 1.10
Initial rate kinetics of the transport of adenosine and 4-amino-7-(beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine (tubercidin) in cultured cells. Cancer Res (1982) 1.10
Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine. Mol Membr Biol (1999) 1.08
Binding of the nucleoside transport inhibitor nitrobenzylthioinosine to HeLa cells. Mol Pharmacol (1977) 1.07
Mediated transport of nucleosides by human erythrocytes. Specificity toward purine nucleosides as permeants. Biochim Biophys Acta (1973) 1.07
Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs. J Biol Chem (1998) 1.06
Adenosine uptake by erythrocytes of man, rat and guinea-pig and its inhibition by hexobendine and dipyridamole. Biochem Pharmacol (1975) 1.04
Physical properties of human polynucleotide kinase: hydrodynamic and spectroscopic studies. Biochemistry (2001) 1.03
Transport of antiviral 3'-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes. Mol Membr Biol (2001) 1.02
Mouse transporter protein, a membrane protein that regulates cellular multidrug resistance, is localized to lysosomes. Cancer Res (1999) 1.02
Distinction between inhibition of purine nucleotide synthesis and the delayed cytotoxic reaction of 6-mercaptopurine. Cancer Res (1974) 1.02
The kinetics of dissociation of the inhibitor of nucleoside transport, nitrobenzylthioinosine, from the high-affinity binding sites of cultured hamster cells. Biochem J (1983) 1.02
Molecular identification of the equilibrative NBMPR-sensitive (es) nucleoside transporter and demonstration of an equilibrative NBMPR-insensitive (ei) transport activity in human erythroleukemia (K562) cells. Neuropharmacology (1997) 1.00
Inward fluxes of adenosine in erythrocytes and cultured cells measured by a quenched-flow method. Biochem J (1984) 1.00
Distinct regional distribution of human equilibrative nucleoside transporter proteins 1 and 2 (hENT1 and hENT2) in the central nervous system. Neuropharmacology (2001) 0.99
Reconstitution studies of the human erythrocyte nucleoside transporter. J Biol Chem (1985) 0.99
Inhibition of uridine uptake in HeLa cells by nitrobenzylthioinosine and related compounds. Mol Pharmacol (1977) 0.99
Nucleoside transport in human erythrocytes. A simple carrier with directional symmetry in fresh cells, but with directional asymmetry in cells from outdated blood. Biochem J (1983) 0.99
Decreased feedback inhibition in a 6-(methylmercapto)purine ribonucleoside-resistant tumor. Cancer Res (1967) 0.99
Fluctuations in nucleoside uptake and binding of the inhibitor of nucleoside transport, nitrobenzylthioinosine, during the replication cycle of HeLa cells. Cancer Res (1979) 0.98
Distribution of equilibrative, nitrobenzylthioinosine-sensitive nucleoside transporters (ENT1) in brain. J Neurochem (1999) 0.97
Inhibition by nitrobenzylthioinosine of adenosine uptake by asynchronous HeLa cells. Mol Pharmacol (1977) 0.97
Use of 4-nitrobenzylthioinosine in the measurement of rates of nucleoside transport in human erythrocytes. Can J Biochem (1972) 0.96
Identification of a novel membrane transporter associated with intracellular membranes by phenotypic complementation in the yeast Saccharomyces cerevisiae. J Biol Chem (1996) 0.96
Inhibition of thymidine uptake in asynchronous HeLa cells by nitrobenzylthioinosine. Exp Cell Res (1977) 0.95
Sodium-dependent, concentrative nucleoside transport in cultured intestinal epithelial cells. Biochem Biophys Res Commun (1986) 0.95
Stage-specific alteration of nucleoside membrane permeability and nitrobenzylthioinosine insensitivity in Plasmodium falciparum infected erythrocytes. Mol Biochem Parasitol (1988) 0.95
Expression of sodium-linked nucleoside transport activity in monolayer cultures of IEC-6 intestinal epithelial cells. J Biol Chem (1990) 0.95
Subcellular distribution and membrane topology of the mammalian concentrative Na+-nucleoside cotransporter rCNT1. J Biol Chem (2001) 0.95
Multidrug transporter P-glycoprotein 170 as a differentiation antigen on normal human lymphocytes and thymocytes: modulation with differentiation stage and during aging. Am J Hematol (1995) 0.94
Differential activity of vincristine and vinblastine against cultured cells. Cancer Res (1984) 0.94
Calcium gradient-dependent and calcium gradient-independent phosphorylation of sarcoplasmic reticulum by orthophosphate. The role of magnesium. Eur J Biochem (1978) 0.93
Parasite-induced processes for adenosine permeation in mouse erythrocytes infected with the malarial parasite Plasmodium yoelii. Biochem J (1990) 0.93
Demonstration of equilibrative nucleoside transporters (hENT1 and hENT2) in nuclear envelopes of cultured human choriocarcinoma (BeWo) cells by functional reconstitution in proteoliposomes. J Biol Chem (1998) 0.92
Inhibitors of inosinate dehydrogenase activity in Ehrlich ascites tumor cells in vitro. Biochem Pharmacol (1974) 0.92
Manipulation of toxicity and tissue distribution of tubercidin in mice by nitrobenzylthioinosine 5'-monophosphate. Biochem Pharmacol (1982) 0.92
Nucleoside transport and metabolism in erythrocytes from the Yucatan miniature pig. Evidence that inosine functions as an in vivo energy substrate. Biochim Biophys Acta (1985) 0.92
[Inhibition of adenosine uptake and stimulation of its effect on isolated hearts of warm-blooded animals by coronary active substances]. Arzneimittelforschung (1969) 0.91
Benzodiazepine inhibition of site-specific binding of nitrobenzylthioinosine, an inhibitor of adenosine transport. Life Sci (1981) 0.91
Binding of nitrobenzylthioinosine to high-affinity sites on the nucleoside-transport mechanism of HeLa cells. Biochem J (1981) 0.90
Distribution of mRNA encoding a nitrobenzylthioinosine-insensitive nucleoside transporter (ENT2) in rat brain. Brain Res Mol Brain Res (1999) 0.90
Improved antitumor effects in 3'-branched homologues of 2'-deoxythioguanosine. Synthesis and evaluation of thioguanine nucleosides of 2,3-dideoxy-3-(hydroxymethyl)-D-erythro-pentofuranose. J Med Chem (1979) 0.90