Published in J Exp Med on October 01, 1981
Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse. J Exp Med (1987) 1.65
Prevention of diabetes in BioBreeding/Worcester rats with monoclonal antibodies that recognize T lymphocytes or natural killer cells. J Exp Med (1986) 1.57
Two genes required for diabetes in BB rats. Evidence from cyclical intercrosses and backcrosses. J Exp Med (1984) 1.28
Type 1 diabetes in the BB rat: a polygenic disease. Diabetes (2009) 1.21
Immune dysfunction in diabetes-prone BB rats. Interleukin 2 production and other mitogen-induced responses are suppressed by activated macrophages. J Exp Med (1984) 1.10
In vivo prevention of thyroid and pancreatic autoimmunity in the BB rat by antibody to class II major histocompatibility complex gene products. Proc Natl Acad Sci U S A (1985) 1.04
Prevention of diabetes mellitus in the BB/W rat with Cyclosporin-A. Am J Pathol (1984) 1.04
The iddm4 locus segregates with diabetes susceptibility in congenic WF.iddm4 rats. Diabetes (2002) 0.98
Mechanisms of autoimmunity in insulin-dependent diabetes mellitus. Clin Exp Immunol (1988) 0.95
Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis. Am J Hum Genet (2000) 0.91
Genetic analysis of the LEW.1AR1-iddm rat: an animal model for spontaneous diabetes mellitus. Mamm Genome (2005) 0.91
A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes. Diabetes (2007) 0.87
Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes. BMC Genet (2005) 0.87
Open reading frame sequencing and structure-based alignment of polypeptides encoded by RT1-Bb, RT1-Ba, RT1-Db, and RT1-Da alleles. Immunogenetics (2004) 0.86
Major histocompatibility complex-linked diabetogenic gene of the nonobese diabetic mouse. Analysis of genomic DNA amplified by the polymerase chain reaction. J Clin Invest (1990) 0.86
Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells. J Clin Invest (1986) 0.85
Experimental autoimmune insulitis. Induction by T lymphocytes specific for a peptide of proinsulin. Am J Pathol (1995) 0.85
Identification of T cell subsets and class I and class II antigen expression in islet grafts and pancreatic islets of diabetic BioBreeding/Worcester rats. Am J Pathol (1988) 0.84
Thymic epithelial defects and predisposition to autoimmune disease in BB rats. Am J Pathol (1994) 0.83
Immunological responses of the BB rat colony in Edinburgh. Immunology (1987) 0.82
Synergistic Interaction of Hypertension and Diabetes in Promoting Kidney Injury and the Role of Endoplasmic Reticulum Stress. Hypertension (2017) 0.82
A major histocompatibility complex class II restriction for BioBreeding/Worcester diabetes-inducing T cells. J Exp Med (1995) 0.82
BB-DR/Edinburgh: a lymphopenic, non-diabetic subline of BB rats. Immunology (1993) 0.79
Liver perisinusoidal fibrosis in BB rats with or without overt diabetes. Am J Pathol (1985) 0.79
Gamma interferon prevents diabetes in the BB rat. Clin Diagn Lab Immunol (1997) 0.78
Elevated apoptosis of peripheral T lymphocytes in diabetic BB rats. Immunology (1999) 0.78
The complete sequence of the MHC class II chain RT.1D alpha u of the diabetic BB rat: mRNA levels of RT1.D alpha in lymphocytes. Nucleic Acids Res (1987) 0.78
Diabetes mellitus in the BB/W rat. Insulitis in pancreatic islet grafts after transplantation in diabetic recipients. Am J Pathol (1986) 0.76
Complementary DNA sequences encoding the rat MHC class II RT1-Bu and RT1-Du alpha and beta chains. Immunogenetics (2003) 0.75
Type I Interferon Is a Catastrophic Feature of the Diabetic Islet Microenvironment. Front Endocrinol (Lausanne) (2017) 0.75
An orthologous non-MHC locus in rats and mice is linked to CD4(+) and CD8(+) T-cell proportion. Genes Immun (2017) 0.75
THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY. Biochem J (1963) 61.56
Coated charcoal immunoassay of insulin. J Clin Endocrinol Metab (1965) 14.95
Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes (1965) 6.00
Aldehyde-fuchsin: a new stain for elastic tissue. Am J Clin Pathol (1950) 4.27
A silver nitrate stain for alpha-2 cells in human pancreatic islets. Acta Soc Med Ups (1968) 3.93
Quantitative studies on the mixed lymphocyte interaction in rats. I. Conditions and parameters of response. J Exp Med (1967) 3.20
The spontaneously diabetic Wistar rat. Metabolic and morphologic studies. Diabetes (1977) 2.70
The spontaneously diabetic Wistar rat (the "BB" rat). Studies prior to and during development of the overt syndrome. Diabetologia (1978) 1.79
Studies of the HLA system and insulin-dependent diabetes mellitus. Diabetes Care (1980) 1.63
Animal model of human disease. Diabetes mellitus. Am J Pathol (1980) 0.97
Membrane properties and functional activity of lymphocytes from cyclophosphamide-pretreated rats. J Immunol (1974) 0.94
Human pancreatic islets in culture: effects of supplementing the medium with homologous and heterologous serum. Science (1976) 0.92
The case for allowing kidney sales. International Forum for Transplant Ethics. Lancet (1998) 5.25
The case for "presumed consent" in organ donation. International Forum for Transplant Ethics. Lancet (1998) 4.99
Should organs from patients in permanent vegetative state be used for transplantation? International Forum for Transplant Ethics. Lancet (1997) 4.04
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nat Genet (1997) 3.62
Solitary maxillary central incisor and short stature. J Pediatr (1977) 2.41
Myofibroblasts from diverse pathologic settings are heterogeneous in their content of actin isoforms and intermediate filament proteins. Lab Invest (1989) 2.30
A controlled trial of hydrocortisone therapy in infants with respiratory distress syndrome. Pediatrics (1972) 1.93
Pathogenesis of a local graft versus host reaction: immunogenicity of circulating host leukocytes. Science (1968) 1.69
Absence of collagen deficiency in familial cerebral aneurysms. J Neurosurg (1989) 1.63
Increased vascular permeability in pancreas of diabetic rats: detection with high resolution protein A-gold cytochemistry. Diabetologia (1992) 1.60
Molecular differential pathology of rhabdomyosarcoma. Genes Chromosomes Cancer (1989) 1.59
Renal transplantation in the inbred rat. 3. A study of heterologous anti-thymocyte sera. J Exp Med (1967) 1.57
Immunologic dysfunction in patients with classic hemophilia receiving lyophilized factor VIII concentrates and cryoprecipitate. Can Med Assoc J (1983) 1.52
Renal transplantation in the inbred rat. IX. Hematopoietic origin of an immunogenic stimulus of rejection. Transplantation (1969) 1.49
Different rates of conversion to IDDM in siblings of type 1 diabetic children: the Montreal family study. Diabetes Res Clin Pract (1993) 1.39
Effects of initial ischemia/reperfusion injury on the transplanted kidney. Transplantation (1997) 1.38
Prolonged rupture of membranes associated with a decreased incidence of respiratory distress syndrome. Pediatrics (1974) 1.38
Enzyme replacement therapy by renal allotransplantation in Fabry's disease. N Engl J Med (1972) 1.38
Spontaneous diabetes mellitus syndrome in the rat. II. T lymphopenia and its association with clinical disease and pancreatic lymphocytic infiltration. J Immunol (1983) 1.33
Dendritic cell-lymphoid cell aggregation and major histocompatibility antigen expression during rat cardiac allograft rejection. J Exp Med (1986) 1.32
Live and learn: patient education delays the need to initiate renal replacement therapy in end-stage renal disease. J Nerv Ment Dis (1993) 1.28
Reduction of immunogenicity of human cadaver renal allografts by donor pretreatment. Transplant Proc (1973) 1.24
The emotional impact of end-stage renal disease: importance of patients' perception of intrusiveness and control. Int J Psychiatry Med (1984) 1.23
Renal transplantation in the inbred rat. I. Morphologic, immunologic, and functional alterations during acute rejection. Transplantation (1967) 1.22
Human renal allografts. Interpretation of morphologic and immunohistochemical observations. Am J Pathol (1968) 1.19
An immunosupressive site of action of heterologous antilymphocyte serum. Lancet (1967) 1.17
Renal transplantation in the inbred rat. II. An immunohistochemical study of acute allograft rejection. Am J Pathol (1968) 1.14
Effect of sodium balance on intrarenal distribution of blood flow in normal man. J Appl Physiol (1970) 1.13
Immune dysfunction in diabetes-prone BB rats. Interleukin 2 production and other mitogen-induced responses are suppressed by activated macrophages. J Exp Med (1984) 1.10
Dynamic time course studies of the spontaneously diabetic BB Wistar rat. III. Light-microscopic and ultrastructural observations of pancreatic islets of Langerhans. Am J Pathol (1982) 1.10
Plasma growth hormone and insulin responses in short children. Am J Dis Child (1969) 1.08
Total parenteral nutrition in malnourished infants with intractable diarrhea. Can Med Assoc J (1977) 1.06
Metabolic aspects of the Beckwith-Wiedemann syndrome. J Pediatr (1973) 1.06
Incidence of IDDM in Montreal by ethnic group and by social class and comparisons with ethnic groups living elsewhere. Diabetes (1988) 1.05
Impact of renal transplantation on uremic cardiomyopathy. Transplantation (1995) 1.04
Incidence of respiratory distress syndrome following antenatal betamethasone: role of sex, type of delivery, and prolonged rupture of membranes. Pediatrics (1981) 1.03
Polygenic nature of spontaneous diabetes in the rat. Permissive MHC haplotype and presence of the lymphopenic trait of the BB rat are not sufficient to produce susceptibility. Diabetes (1992) 1.01
Malignant lymphoma in spontaneously diabetic rats. N Engl J Med (1979) 1.01
Peripheral total parenteral nutrition for premature infants with the respiratory distress syndrome: a controlled study. J Pediatr (1978) 1.00
The impact of renal transplantation on the course of hepatitis B liver disease. Transplantation (1985) 1.00
Genetics of acute rejection of rat cardiac allografts and a model of hyperacute rejection. Transplantation (1974) 1.00
Epidemiologic survey of juvenile-onset diabetes in Montreal. Diabetes (1979) 1.00
The antenatal use of betamethasone in the prevention of respiratory distress syndrome: a controlled double-blind study. Pediatrics (1979) 0.99
Spontaneous diabetes mellitus syndrome in the rat. IV. Immunogenetic interactions of MHC and non-MHC components of the syndrome. Metabolism (1983) 0.99
Nonessential role of neutrophils as mediators of hyperacute cardiac allograft rejection in the rat. Lab Invest (1976) 0.98
Clinicopathologic study of cutaneous melanoma of the head and neck. Am J Surg (1972) 0.97
Animal model of human disease. Diabetes mellitus. Am J Pathol (1980) 0.97
Renal transplantation in the inbred rat. 13. Modification of rejection by active immunization with bone marrow cells. Transplantation (1970) 0.97
The effect of anticomplementary cobra venom factor on hyperacute rat cardiac allograft rejection. Lab Invest (1978) 0.96
Histologic, ultrastructural and hormonal characterization of a pituitary tumor secreting both HGH and prolactin. J Clin Endocrinol Metab (1973) 0.96
Renal transplantation in the inbred rat. IV. Alterations in the microvasculature in acute unmodified rejection. Transplantation (1968) 0.96
Nephritis induced by antilymphocyte serum. An electron microscopic and immunohistochemical study. Transplantation (1969) 0.96
A controlled sequential morphologic study of hyperacute cardiac allograft rejection in the rat. Lab Invest (1975) 0.96
Depressed T cells following neonatal steroid treatment. Pediatrics (1981) 0.95
Evidence for complement-induced endothelial injury in vivo: a comparative ultrastructural tracer study in a controlled model of hyperacute rat cardiac allograft rejection. Am J Pathol (1982) 0.95
Membrane properties and functional activity of lymphocytes from cyclophosphamide-pretreated rats. J Immunol (1974) 0.94
Metabolic effects of exchange transfusion. II. Delayed hypoglycemia following exchange transfusion with citrated blood. J Pediatr (1971) 0.94
HNK-1+ (Leu-7) and other lymphocyte subsets in long-term survivors with renal allotransplants. Transplantation (1985) 0.94
Bacille Calmette-Guérin vaccination and incidence of IDDM in Montreal, Canada. Diabetes Care (1997) 0.93
Renal transplantation (second of two parts). N Engl J Med (1979) 0.93
Immunosuppression and rehabilitation following cadaveric renal transplantation. New developments. Urology (1973) 0.93
Augmentation of proliferation of human mixed lymphocyte culture by human alpha-fetoprotein. J Immunol (1977) 0.92
Human pancreatic islets in culture: effects of supplementing the medium with homologous and heterologous serum. Science (1976) 0.92
A simplified method for the quantitation of in vitro leucocyte culture. Int Arch Allergy Appl Immunol (1968) 0.92
Renal transplantation in the inbred rat. XIV. Mechanism of the modified rejection produced by bone marrow cell pretreatment. Transplantation (1970) 0.92
Two-color immunofluorescence and flow cytometry analysis of lymphocytes in long-term renal allotransplant recipients: identification of a major Leu-7+/Leu-3+ subpopulation. J Immunol (1985) 0.92
The syndrome of multiple aucosal neuromas and medullary thyroid carcinoma in childhood. Importance of recognition of the phenotype for the early detection of malignancy. J Pediatr (1975) 0.91
Insulin-dependent diabetes mellitus is associated with genes that map to the right of the class I RT1.A locus of the major histocompatibility complex of the rat. Diabetes (1986) 0.91
Treatment with heterologous anithymus sera: nephritis associated with modification of renal allograft rejection and the immune status of the host to the foreign protein. Transplantation (1967) 0.91
Renal transplantation in the inbred rat. XV. An assay study of three immunosuppressive drugs. Transplantation (1970) 0.90
Imprinted and genotype-specific expression of genes at the IDDM2 locus in pancreas and leucocytes. J Autoimmun (1996) 0.90
Metabolic effects of exchange transfusions. I. Effect of citrated and of heparinized blood on glucose, nonesterified fatty acids, 2-(4 hydroxybenzeneazo) benzoic acid binding, and insulin. J Pediatr (1971) 0.90
Left ventricular hypertrophy in end-stage renal disease. Nephron (1988) 0.90
Ultradian growth hormone rhythm in the rat: effects of feeding, hyperglycemia, and insulin-induced hypoglycemia. Endocrinology (1976) 0.89
Parental imprinting effect at the INS-IGF2 diabetes susceptibility locus. Diabetologia (1995) 0.89
Measurement of plasma cortisol in children and adults: a comparison of the double isotope derivative assay, competitive protein-binding analysis and the modified competitive protein-binding analysis. J Clin Endocrinol Metab (1970) 0.89
Immunologic and genetic studies of diabetes in the BB rat. Crit Rev Immunol (1989) 0.89
A controlled serial ultrastructural tracer study of first-set cardiac allograft rejection in the rat. Evidence that the microvascular endothelium is the primary target of graft destruction. Am J Pathol (1983) 0.89
The clinical and pathological course of hepatitis B liver disease in renal transplant recipients. Transplantation (1984) 0.88
Hyperbilirubinaemia and idiopathic hypopituitarism in the newborn period. Acta Paediatr Scand (1979) 0.88
Peyer's patch cells. Absence of graft-versus-host reactivity in mice and rats. Lab Invest (1972) 0.87
IDDM in BB rats. Enhanced MHC class I heavy-chain gene expression in pancreatic islets. Diabetes (1988) 0.87
Renal transplantation in the inbred rat. VI. Electron microscopic study of the mononuclear cells accumulating in rejecting renal allografts. Transplantation (1971) 0.87
A study of the relationship of virus-like particles and Australia antigen in liver. Hum Pathol (1974) 0.87
Fluorescence activated cell sorter analysis of lymphocytes following renal allotransplantation. Transplant Proc (1981) 0.87
Renal transplantation in the inbred rat. XI. Reduction of allograft immunogenicity by cytotoxic drug pretreatment of donors. Transplantation (1969) 0.87
Chronic hepatitis in end-stage renal disease: comparison of HBsAg-negative and HBsAg-positive patients. Kidney Int (1985) 0.87
Hepatitis B disease in dialysis and transplant patients. Further epidemiologic and serologic studies. Transplantation (1987) 0.86
Pancreatic cellular infiltrates in autoimmune-prone New Zealand Black mice. Diabetologia (1984) 0.86
Improvement in cadaveric renal transplant survival. Arch Surg (1973) 0.86
Transplantation and home hemodialysis: their cost-effectiveness. J Chronic Dis (1985) 0.86
Prognostic factors in cutaneous melanoma of the head and neck. Am J Pathol (1973) 0.86
Renal transplantation in the inbred rat. VII. Ultrastructure of the glomerulus during acute renal allograft rejection. Transplantation (1971) 0.86