Published in J Cell Biol on April 01, 1982
Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody. Proc Natl Acad Sci U S A (1983) 5.00
Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system. J Cell Biol (1988) 2.31
Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase. Mol Cell Biol (2001) 2.24
Tyrosine phosphorylation of specific proteins after mitogen stimulation of chicken embryo fibroblasts. Mol Cell Biol (1983) 1.92
Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7. Proc Natl Acad Sci U S A (1988) 1.91
Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation. Proc Natl Acad Sci U S A (1986) 1.72
Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor. J Clin Invest (1998) 1.70
Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors. J Cell Biol (1989) 1.68
Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells. J Clin Invest (1985) 1.58
Altered epidermal growth factor (EGF)-stimulated protein kinase activity in variant A431 cells with altered growth responses to EGF. Proc Natl Acad Sci U S A (1982) 1.47
High affinity epidermal growth factor receptors on the surface of A431 cells have restricted lateral diffusion. EMBO J (1984) 1.46
Expression of epidermal growth factor receptor (EGF-R) in human lung tumours. Br J Cancer (1986) 1.45
Properties of a monoclonal antibody to epidermal growth factor receptor with implications for the mechanism of action of EGF. EMBO J (1984) 1.34
Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition. J Cell Biol (1995) 1.23
Epidermal growth factor inhibits the synthesis of the nuclear protein cyclin in A431 human carcinoma cells. Proc Natl Acad Sci U S A (1984) 1.22
Thiol protease-specific inhibitor E-64 arrests human epidermoid carcinoma A431 cells at mitotic metaphase. Proc Natl Acad Sci U S A (1988) 1.18
Consumption of EGF by A431 cells: evidence for receptor recycling. J Cell Biol (1993) 1.13
Epidermal growth factor-induced selective phosphorylation of cultured rat hepatocyte 55-kD cytokeratin before filament reorganization and DNA synthesis. J Cell Biol (1989) 1.11
Down-regulation of epidermal growth factor receptor correlates with plasminogen activator activity in human A431 epidermoid carcinoma cells. Proc Natl Acad Sci U S A (1983) 1.10
Interleukin 2 inhibits in vitro growth of human T cell lines carrying retrovirus. J Exp Med (1985) 1.08
Epidermal growth factor stimulates glycogen synthase activity in cultured cells. Proc Natl Acad Sci U S A (1985) 1.02
Cell targeting with hybrid Qβ virus-like particles displaying epidermal growth factor. Chembiochem (2011) 0.97
Optical biosensor differentiates signaling of endogenous PAR1 and PAR2 in A431 cells. BMC Cell Biol (2007) 0.95
Expression and biosynthetic variation of the epidermal growth factor receptor in human hepatocellular carcinoma-derived cell lines. Mol Cell Biol (1988) 0.93
The effects of intracolonic EGF on mucosal growth and experimental carcinogenesis. Br J Cancer (1991) 0.91
Rapid uptake of tyrphostin into A431 human epidermoid cells is followed by delayed inhibition of epidermal growth factor (EGF)-stimulated EGF receptor tyrosine kinase activity. Mol Cell Biol (1991) 0.90
Oncogenic KRAS impairs EGFR antibodies' efficiency by C/EBPβ-dependent suppression of EGFR expression. Neoplasia (2012) 0.90
Recombinant human epidermal growth factor treatment of radiation-induced severe oral mucositis in patients with head and neck malignancies. Eur J Cancer Care (Engl) (2009) 0.88
Expression of oncogenes in thyroid tumours: coexpression of c-erbB2/neu and c-erbB. Br J Cancer (1988) 0.88
Induction of human NF-IL6beta by epidermal growth factor is mediated through the p38 signaling pathway and cAMP response element-binding protein activation in A431 cells. Mol Biol Cell (2005) 0.88
Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s). Br J Cancer (1997) 0.88
Changes in epidermal growth factor receptor expression and response to ligand associated with acquired tamoxifen resistance or oestrogen independence in the ZR-75-1 human breast cancer cell line. Br J Cancer (1992) 0.85
MicroRNAs are part of the regulatory network that controls EGF induced apoptosis, including elements of the JAK/STAT pathway, in A431 cells. PLoS One (2015) 0.84
Two independent mechanisms for escaping epidermal growth factor-mediated growth inhibition in epidermal growth factor receptor-hyperproducing human tumor cells. J Cell Biol (1988) 0.83
Isolation and characterization of epinectin, a novel adhesion protein for epithelial cells. J Cell Biol (1984) 0.83
Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug development. PLoS One (2014) 0.83
Epidermal-growth-factor-induced production of phosphatidylalcohols by HeLa cells and A431 cells through activation of phospholipase D. Biochem J (1992) 0.83
Anti-EGF receptor monoclonal antibodies: biological studies and potential clinical applications. Trans Am Clin Climatol Assoc (1989) 0.82
Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization. Mol Cell Proteomics (2013) 0.81
Growth control by epidermal growth factor and transforming growth factor-alpha in human lung squamous carcinoma cells. Br J Cancer (1992) 0.81
Design of a modular protein-based MRI contrast agent for targeted application. PLoS One (2013) 0.80
Nanoconjugation: A Materials Approach to Enhance Epidermal Growth Factor Induced Apoptosis. Biomater Sci (2014) 0.78
Modulation of type-IV procollagen and laminin production in A431 human squamous epidermoid carcinoma cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) and epidermal growth factor (EGF). Arch Dermatol Res (1985) 0.78
Physiological epidermal growth factor concentrations activate high affinity receptors to elicit calcium oscillations. PLoS One (2014) 0.76
Cellular uptake of radioiodine delivered by trastuzumab can be modified by the addition of epidermal growth factor. Eur J Nucl Med Mol Imaging (2005) 0.76
A Nonpolycationic Fully Proteinaceous Multiagent System for Potent Targeted Delivery of siRNA. Mol Ther Nucleic Acids (2014) 0.76
Cellular-level surgery using nano robots. J Lab Autom (2012) 0.75
Cytokinesis Failure Leading to Chromosome Instability in v-Src-Induced Oncogenesis. Int J Mol Sci (2017) 0.75
Development of an ErbB-overexpressing A-431 optical reporting tumor xenograft model to assess targeted photodynamic therapy regimens. Photochem Photobiol (2010) 0.75
The paradoxical functions of EGFR during breast cancer progression. Signal Transduct Target Ther (2017) 0.75
Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D. Oncotarget (2016) 0.75
Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases. Elife (2016) 0.75
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Role of cell shape in growth control. Nature (1978) 12.46
Epidermal growth factor. Annu Rev Biochem (1979) 11.82
Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes. J Biol Chem (1980) 7.71
Nerve growth factor receptors on human melanoma cells in culture. Proc Natl Acad Sci U S A (1977) 6.62
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc Natl Acad Sci U S A (1978) 5.91
Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431. J Cell Biol (1979) 5.62
Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. J Biol Chem (1980) 5.19
Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell (1981) 5.08
Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro. Nature (1978) 3.54
Hormone receptor topology and dynamics: morphological analysis using ferritin-labeled epidermal growth factor. Proc Natl Acad Sci U S A (1979) 3.54
Serum-free cell culture: a unifying approach. Cell (1980) 3.41
Methods for growth of cultured cells in serum-free medium. Anal Biochem (1980) 3.27
Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor. J Biol Chem (1979) 3.18
Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor. J Cell Biol (1979) 2.88
Determination of cellular shape by the extracellular matrix and its correlation with the control of cellular growth. Cancer Res (1978) 2.86
Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells. Nature (1981) 2.75
Rapid induction of morphological changes in human carcinoma cells A-431 by epidermal growth factors. J Cell Biol (1979) 2.61
Growth and maintenance of HeLa cells in serum-free medium supplemented with hormones. Proc Natl Acad Sci U S A (1978) 2.31
Inefficient internalization of receptor-bound low density lipoprotein in human carcinoma A-431 cells. J Cell Biol (1981) 1.88
Fibronectin mediates cytokinesis and growth of rat follicular cells in serum-free medium. Cell (1979) 1.62
Identification of epidermal growth factor receptors in a hyperproducing human epidermoid carcinoma cell line. J Biol Chem (1979) 1.53
Epidermal growth factor and thyrotropin-releasing hormone act similarly on a clonal pituitary cell strain. Modulation of hormone production and inhbition of cell proliferation. J Cell Biol (1980) 1.52
Rapid rounding of human epidermoid carcinoma cells A-431 induced by epidermal growth factor. J Cell Biol (1981) 1.52
Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus. J Cell Biol (1981) 1.34
Effects of a serum spreading factor on growth and morphology of cells in serum-free medium. J Supramol Struct (1980) 1.27
Production and characterization of antibody blocking epidermal growth factor:receptor interactions. Biochim Biophys Acta (1980) 1.21
Epidermal growth factor and expression of specific genes: effects on cultured rat pituitary cells are dissociable from the mitogenic response. Proc Natl Acad Sci U S A (1980) 1.21
Phosphoethanolamine as a growth factor of a mammary carcinoma cell line of rat. Proc Natl Acad Sci U S A (1979) 1.20
The growth requirements of SV40 virus transformed Balb/c-3T3 cells in serum-free monolayer culture. J Cell Physiol (1980) 1.10
Stimulation of clonal growth of normal fibroblasts with substrata coated with basic polymers. J Cell Biol (1976) 1.10
Growth and differentiation of embryonal carcinoma cell line F9 in defined media. Proc Natl Acad Sci U S A (1980) 1.02
Solubilization of membrane receptor for epidermal growth factor. Life Sci (1979) 1.01
Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines. Food Chem Toxicol (1999) 1.62
Isolation of human serum spreading factor. J Biol Chem (1983) 1.61
Extended culture of mouse embryo cells without senescence: inhibition by serum. Science (1987) 1.43
Characterization of human serum spreading factor with monoclonal antibody. Proc Natl Acad Sci U S A (1983) 1.33
Death of serum-free mouse embryo cells caused by epidermal growth factor deprivation. J Cell Biol (1991) 1.13
CNS diseases associated with varicella zoster virus and herpes simplex virus infection. Pathogenesis and current therapy. Neurol Clin (1986) 1.12
Local origin of fibroblasts deduced from sarcomas induced in chimaeras by implants of pliable disks. Nature (1971) 1.06
Stimulation of haptotaxis and migration of tumor cells by serum spreading factor. Cancer Res (1985) 1.06
Haemopoietic stem cells in the peripheral blood. Lancet (1967) 1.05
Quantitation of spreading factor in human biologic fluids. J Lab Clin Med (1984) 1.04
Continuous in vitro propagation and differentiation of cultures of the intramolluscan stages of the human parasite Schistosoma mansoni. Proc Natl Acad Sci U S A (1999) 1.04
Heparin-binding properties of human serum spreading factor. J Biol Chem (1985) 1.03
Binding of Staphylococcus aureus by human serum spreading factor in an in vitro assay. Infect Immun (1986) 1.02
Stimulation of sugar uptake and thymidine incorporation in mouse 3T3 cells by calcium phosphate and other extracellular particles. Proc Natl Acad Sci U S A (1977) 1.02
Toxicology of chloral hydrate in the mouse. Environ Health Perspect (1982) 1.02
Zebrafish (Danio rerio) p53 tumor suppressor gene: cDNA sequence and expression during embryogenesis. Mol Mar Biol Biotechnol (1997) 1.01
ES-like cell cultures derived from early zebrafish embryos. Mol Mar Biol Biotechnol (1995) 0.98
Effects of fibronectin-related peptides on cell spreading. In Vitro Cell Dev Biol (1985) 0.97
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Culture of cells from zebrafish (Brachydanio rerio) embryo and adult tissues. Cell Biol Toxicol (1992) 0.88
The effects of maleic anhydride-divinyl ether (MVE) copolymers on hepatic microsomal mixed-function oxidases and other biologic activities. J Pharmacol Exp Ther (1979) 0.87
Basic fibroblast growth factor stimulates proliferation and suppresses melanogenesis in cell cultures derived from early zebrafish embryos. Mol Mar Biol Biotechnol (1994) 0.86
Induction of hypoxia in normal and malignant tissues by changing the oxygen affinity of hemoglobin--implications for therapy. Int J Radiat Oncol Biol Phys (1986) 0.86
Selection of transformed cells in serum-free media. In Vitro Cell Dev Biol (1985) 0.86
Classical and molecular cytogenetics of the pufferfish Tetraodon nigroviridis. Chromosome Res (1999) 0.84
Culture of cells from juvenile worms of Schistosoma mansoni. J Parasitol (1993) 0.83
Axenic culture of Schistosoma mansoni sporocysts in low O2 environments. J Parasitol (2001) 0.83
Aplastic anaemia in sublethally irradiated mice given allogeneic lymph node cells. Br J Haematol (1967) 0.83
Delayed mortality after mid-lethal exposures to wholebody irradiation and its modification by treatment with syngeneic lymph-node or bone-marrow cells. Int J Radiat Biol Relat Stud Phys Chem Med (1966) 0.82
In vitro cultivation of cells from larval Schistosoma mansoni. J Parasitol (1994) 0.82
Human spreading factor: synthesis and response by HepG2 hepatoma cells in culture. J Cell Physiol (1985) 0.81
Human serum spreading factor: relationship to somatomedin B. J Clin Endocrinol Metab (1984) 0.81
Serial passage of embryonic human astrocytes in serum-free, hormone-supplemented medium. J Neurosci Res (1991) 0.80
Suppression of humoral antibody production by exposure to 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin. J Pharmacol Exp Ther (1984) 0.80
Relationship of molecular weight to antiviral and antitumor activities and toxic effects of maleic anhydride-divinyl ether (MVE) polyanions. Cancer Treat Rep (1978) 0.80
Mitogenic activity from trout embryos. Proc Natl Acad Sci U S A (1990) 0.80
Culture of cells from two life stages of Schistosoma mansoni. Cytotechnology (1997) 0.80
A biologically active thrombin cleavage product of human serum spreading factor. Biochem Biophys Res Commun (1984) 0.79
Bcl-2 inhibits cell death of serum-free mouse embryo cells caused by epidermal growth factor deprivation. Cell Biol Toxicol (1998) 0.79
Characterization of cell cultures derived from Fugu, the Japanese pufferfish. Mol Mar Biol Biotechnol (1997) 0.79
Immunotoxicological investigations in the mouse: general approach and methods. Drug Chem Toxicol (1985) 0.78
The role of lysosomes in exercise-induced hepatic protein loss. Biochem J (1982) 0.78
The relative biological effectiveness of fractionated doses of fast neutrons (42 MeVd----Be) for normal tissues in the pig. II. Late effects on cutaneous and subcutaneous tissues. Br J Radiol (1990) 0.78
Vagus nerve stimulation for intractable seizures: one year follow-up. J Neurosci Nurs (1993) 0.78
Glass-bead affinity chromatography of cell attachment and spreading-promoting factors of human serum. Anal Biochem (1984) 0.78
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Splenosis: a beneficial condition. J R Soc Med (1984) 0.75
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