Published in J Exp Med on May 01, 1982
Polyclonal B cell activation, circulating immune complexes and autoimmunity in human american visceral leishmaniasis. Clin Exp Immunol (1984) 2.13
Induction of murine autoimmune disease by chronic polyclonal B cell activation. J Exp Med (1983) 2.06
Normal mice express idiotypes related to autoantibody idiotypes of lupus mice. Proc Natl Acad Sci U S A (1983) 1.50
Autoimmune disease and malignant lymphoma associated with host-versus-graft disease in mice. Clin Exp Immunol (1985) 0.99
Presence of shared idiotypes in serum and immune complexes in patients with IgA nephropathy. Clin Exp Immunol (1987) 0.87
IgA mesangial deposits in C3H/HeJ mice after oral immunization with ferritin or bovine serum albumin. Clin Exp Immunol (1986) 0.83
Isolation and analysis of nephritic-producing immune complexes in Plasmodium berghei-infected mice. J Natl Med Assoc (1995) 0.80
An idiotope-specific autoantibody in SLE. Clin Exp Immunol (1988) 0.77
In vivo modulation of polyclonal activation of lymphocytes by SOAz, a cyclophosphazene derived drug. Prevention of murine glomerulonephritis induced by chronic injections of lipopolysaccharide. Clin Exp Immunol (1985) 0.77
Characterization of circulating idiotypes containing immune complexes and their presence in the glomerular mesangium in patients with IgA nephropathy. Clin Exp Immunol (1989) 0.77
Characterization of immune complexes in acute lymphoblastic leukaemia. Clin Exp Immunol (1983) 0.75
Solubilization of immune complex deposits by native 7S IgG molecules in lupus glomerulonephritis--a possible antigen excess effect on rheumatoid factor-IgG complexes. Clin Exp Immunol (1984) 0.75
Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry (1965) 96.68
A method of trace iodination of proteins for immunologic studies. Int Arch Allergy Appl Immunol (1966) 43.66
The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Biochem J (1973) 22.93
Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. J Biol Chem (1970) 19.51
Towards a network theory of the immune system. Ann Immunol (Paris) (1974) 16.43
Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med (1968) 8.91
Immunoglobulin-producing tumors and myeloma proteins of mice. Physiol Rev (1972) 4.63
Affinity labeling of a phosphorylcholine binding mouse myeloma protein. Biochemistry (1972) 4.26
Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease. J Immunol (1978) 3.78
The pathogenesis of glomerulonephritis. Am J Med (1968) 3.61
In situ immune complex formation and glomerular injury. Kidney Int (1980) 3.52
Solid-phase enzyme immunoassay or radioimmunoassay for the detection of immune complexes based on their recognition by conglutinin: conglutinin-binding test. A comparative study with 125I-labelled Clq binding and Raji-cell RIA tests. Clin Exp Immunol (1977) 3.27
Affinity labeling of a mouse myeloma protein which binds nitrophenyl ligands. Kinetics of labeling and isolation of a labeled peptide. Biochemistry (1970) 2.88
Possible role of a B-cell mitogen in hypergammaglobulinaemia in malaria and trypanosomiasis. Lancet (1974) 2.83
Most IgM-producing cells in the mouse secrete auto-antibodies (rheumatoid factor). Nature (1978) 2.59
Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes. J Exp Med (1977) 2.58
C1g precipitins in the sera of patients with systemic lupus erythematosus and other hypocomplementemic states: characterization of high and low molecular weight types. J Exp Med (1971) 2.43
Release of DNA in circulating blood and induction of anti-DNA antibodies after injection of bacterial lipopolysaccharides. J Exp Med (1974) 2.34
Network theory in autoimmunity. In vitro suppression of serum anti-DNA antibody binding to DNA by anti-idiotypic antibody in systemic lupus erythematosus. J Clin Invest (1981) 2.24
Clonal nature of the immune response to phosphorylcholine. II. Idiotypic specificity and binding characteristics of anti-phosphorylcholine antibodies. J Immunol (1974) 1.95
Antigen quantitation in experimental immune complex glomerulonephritis. I. Acute serum sickness. J Immunol (1970) 1.93
Autoimmune response to DNA, red blood cells, and thymocyte antigens in association with polyclonal antibody synthesis during experimental African trypanosomiasis. J Immunol (1979) 1.60
Antiidiotypic activity in the IgM fractions of mixed cryoglobulins. J Immunol (1980) 1.55
Purification of bovine conglutinin using pepsin digestion. Mol Immunol (1981) 1.15
The natural occurence of circulating idiotype--anti-idiotype complexes during a secondary immune response to phosphorylcholine. Clin Immunol Immunopathol (1980) 1.09
Simultaneous induction of an idiotype, corresponding anti-idiotypic antibodies, and immune complexes during African trypanosomiasis in mice. J Immunol (1982) 1.08
Phosphorylcholine-binding hybridoma proteins of normal and idiotypically suppressed BALB/c mice I. Characterization and idiotypic analysis. Eur J Immunol (1980) 1.02
Immune complex detection in glomerular diseases. Nephron (1979) 0.95
What are circulating immune complexes doing in glomerulonephritis? N Engl J Med (1981) 0.90
Pathogenesis of the glomerulonephritis of NZB/W mice. J Exp Med (1968) 8.91
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science (1987) 7.01
Tumor necrosis factor and disease severity in children with falciparum malaria. N Engl J Med (1989) 6.79
Circulating and intra-articular immune complexes in patients with rheumatoid arthritis. Correlation of 125I-Clq binding activity with clinical and biological features of the disease. J Clin Invest (1976) 5.96
Circulating immune complexes in the serum in systemic lupus erythematosus and in carriers of hepatitis B antigen. Quantitation by binding to radiolabeled C1q. J Clin Invest (1974) 5.81
Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura. N Engl J Med (1988) 4.69
Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J Exp Med (1993) 4.30
Detection of antibodies and soluble antigen-antibody complexes by precipitation with polyethylene glycol. J Immunol (1973) 4.28
Diaphragm function and alveolar hypoventilation. Q J Med (1976) 3.94
Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study. BMJ (2000) 3.45
Solid-phase enzyme immunoassay or radioimmunoassay for the detection of immune complexes based on their recognition by conglutinin: conglutinin-binding test. A comparative study with 125I-labelled Clq binding and Raji-cell RIA tests. Clin Exp Immunol (1977) 3.27
An IgG-Fc receptor induced in cytomegalovirus-infected human fibroblasts. J Immunol (1976) 3.14
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc Natl Acad Sci U S A (1989) 3.03
Complement breakdown products in plasma from patients with systemic lupus erythematosus and patients with membranoproliferative or other glomerulonephritis. J Clin Invest (1975) 2.97
Brief report: clonal proliferation of type 2 helper T cells in a man with the hypereosinophilic syndrome. N Engl J Med (1994) 2.96
L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol (1986) 2.79
Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia. Clin Infect Dis (1998) 2.78
Induction of thromboses within renal grafts by high-dose prophylactic OKT3. Lancet (1992) 2.66
Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes. J Exp Med (1977) 2.58
Deficient IL-12(p35) gene expression by dendritic cells derived from neonatal monocytes. J Immunol (2001) 2.56
Spleen cell cytokine secretion in Mycobacterium bovis BCG-infected mice. Infect Immun (1992) 2.50
Determination of anti-DNA antibodies by a modified 125I-labelled DNA-binding test. Elimination of non-specific binding of DNA to non-immunoglobulin basic proteins by using an anionic detergent. Clin Exp Immunol (1976) 2.50
Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha, and interferon-gamma in the serum of patients with septic shock. Swiss-Dutch J5 Immunoglobulin Study Group. J Infect Dis (1990) 2.36
Fluorouracil and recombinant alfa-2a-interferon: an active regimen against advanced colorectal carcinoma. J Clin Oncol (1989) 2.36
Release of DNA in circulating blood and induction of anti-DNA antibodies after injection of bacterial lipopolysaccharides. J Exp Med (1974) 2.34
Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunol Rev (1989) 2.22
Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum (1997) 2.21
A phase 1/2 clinical trial of enzyme replacement in fabry disease: pharmacokinetic, substrate clearance, and safety studies. Am J Hum Genet (2001) 2.13
Polyclonal B cell activation, circulating immune complexes and autoimmunity in human american visceral leishmaniasis. Clin Exp Immunol (1984) 2.13
Antibodies to common leukocyte antigen p220 influence human T cell proliferation by modifying IL 2 receptor expression. J Immunol (1985) 2.11
A simplified measurement of respiratory resistance by forced oscillation. J Appl Physiol (1970) 2.11
Inhibition of P. falciparum growth in human erythrocytes by monoclonal antibodies. Nature (1981) 2.05
Interleukin-10 production during septicaemia. Lancet (1994) 2.05
Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. Hepatology (1998) 2.04
Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes. Eur J Immunol (1994) 2.04
Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8. Mol Cell (2001) 2.02
Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J Exp Med (1994) 2.01
Validity of performance scales for disability assessment in multiple sclerosis. Mult Scler (2007) 1.99
Circulating complement breakdown products in patients with rheumatoid arthritis. Correlation between plasma C3d, circulating immune complexes, and clinical activity. J Clin Invest (1977) 1.97
Neonatal bacillus Calmette-Guérin vaccination induces adult-like IFN-gamma production by CD4+ T lymphocytes. Eur J Immunol (2001) 1.96
Endogenous IL-10 protects mice from death during septic peritonitis. J Immunol (1995) 1.94
A scanning electron microscopic comparison of a high volume final flush with several irrigating solutions: Part 3. J Endod (1983) 1.94
Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting. Eur J Immunol (1996) 1.92
Interleukin-10 controls interferon-gamma and tumor necrosis factor production during experimental endotoxemia. Eur J Immunol (1994) 1.92
Spontaneous secretion of interferon gamma and interleukin 4 by human intraepithelial and lamina propria gut lymphocytes. Gut (1998) 1.88
Interleukin-10 impairs host defense in murine pneumococcal pneumonia. J Infect Dis (1996) 1.88
Comparison of the immune responsiveness of NZB and NZB X NZW F1 hybrid mice with that of other strains of mice. J Exp Med (1969) 1.87
Basophil activation tests for the diagnosis of food allergy in children. Clin Exp Allergy (2009) 1.83
Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate. Cancer Res (1991) 1.79
Alloreactive cloned T cell lines. VI. Multiple lymphokine activities secreted by helper and cytolytic cloned T lymphocytes. J Immunol (1982) 1.78
Investigation of the increased incidence of gonorrhoea diagnosed in genitourinary medicine clinics in England, 1994-6. Sex Transm Infect (2000) 1.78
Interleukin-10 modulates susceptibility in experimental cerebral malaria. Immunology (1997) 1.73
The antibody response in mice to carrier-free synthetic polymers of Plasmodium falciparum circumsporozoite repetitive epitope is I-Ab-restricted: possible implications for malaria vaccines. J Immunol (1986) 1.71
Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol (1998) 1.70
Detection of blood chimerism after lung and heart-lung transplantation. The superiority of nested as compared with standard polymerase chain reaction amplification. Transplantation (1994) 1.69
Adolescents are not adults: developmental considerations in alcohol users. Alcohol Clin Exp Res (2000) 1.69
Failure to detect circulating DNA--anti-DNA complexes by four radioimmunological methods in patients with systemic lupus erythematosus. Clin Exp Immunol (1977) 1.66
Immune complexes and complement hypercatabolism in patients with leprosy. Clin Exp Immunol (1976) 1.66
Human cytokine responses to cardiac transplantation and coronary artery bypass grafting. J Thorac Cardiovasc Surg (1996) 1.63
Autoimmune response to DNA, red blood cells, and thymocyte antigens in association with polyclonal antibody synthesis during experimental African trypanosomiasis. J Immunol (1979) 1.60
Genesis of antinuclear antibody in NZB-W mice: role of genetic factors and of viral infections. Clin Exp Immunol (1970) 1.59
Toxicology and pharmacology of the chemical warfare agent sulfur mustard. Pharmacol Rev (1996) 1.59
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SDS-PAGE analysis of M. leprae protein antigens reacting with antibodies from sera from lepromatous patients and infected armadillos. Clin Exp Immunol (1982) 1.56
Antibodies to the repetitive epitope of Plasmodium falciparum circumsporozoite protein in a rural Tanzanian community: a longitudinal study of 132 children. Am J Trop Med Hyg (1987) 1.55
Immune complexes in serum and in cerebrospinal fluid in African trypanosomiasis. Correlation with polyclonal B cell activation and with intracerebral immunoglobulin synthesis. J Clin Invest (1981) 1.55
Does 111indium-platelet deposition predict patency in prosthetic arterial grafts? Br J Surg (1983) 1.55
Autoimmunity after induction of neonatal tolerance to alloantigens: role of B cell chimerism and F1 donor B cell activation. J Immunol (1986) 1.54
Vaccination against typhoid fever: present status. Bull World Health Organ (1994) 1.52
Intranasal midazolam as a treatment of autonomic crisis in patients with familial dysautonomia. Pediatr Neurol (2000) 1.52
An improved microfluorimeter for measuring brightness of fluorescent antibody reactions. J Histochem Cytochem (1967) 1.51
Abnormal T-cell phenotype in familial erythrophagocytic lymphohistiocytosis. Lancet (1993) 1.51
Transfusion-transmitted malaria in Canada. CMAJ (2001) 1.51
Release of tumor necrosis factor, interleukin-2, and gamma-interferon in serum after injection of OKT3 monoclonal antibody in kidney transplant recipients. Transplantation (1989) 1.50
T cell-mediated immune responses in human newborns: ready to learn? Clin Exp Immunol (2005) 1.50
Remission and immune reconstitution after T-cell-depleted stem-cell transplantation for rheumatoid arthritis. Lancet (1998) 1.49
Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia. J Exp Med (1990) 1.48
Detection of anti-glomerular basement membrane antibodies by radioimmunological technique. Clinical application in human nephropathies. J Clin Invest (1974) 1.48
Effector functions of circumsporozoite peptide-primed CD4+ T cell clones against Plasmodium yoelii liver stages. J Immunol (1993) 1.48
Evaluation of a fluorescent antibody test for amebiasis using two widely differing ameba strains as antigen. Am J Trop Med Hyg (1966) 1.46
The global impact of the Chernobyl reactor accident. Science (1988) 1.44
Clonal Th2 lymphocytes in patients with the idiopathic hypereosinophilic syndrome. Br J Haematol (2000) 1.44
TH2 activated cells prevent experimental autoimmune uveoretinitis, a TH1-dependent autoimmune disease. Eur J Immunol (1993) 1.44
Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood dendritic cells. Eur J Immunol (1995) 1.43
IgG3 is the major source of cryoglobulins in mice. J Immunol (1989) 1.42
Low dose low osmolar intravenous urography. Clin Radiol (1987) 1.40
Bulging fontanelle in febrile infants: is lumbar puncture mandatory? Arch Dis Child (2009) 1.39
The assessment of diaphragm function. Medicine (Baltimore) (1977) 1.39
Effect of coadministration of a nutritional supplement on ciprofloxacin absorption. Am J Hosp Pharm (1994) 1.39
Universal leucocyte-depletion of blood components: cell concentrates and plasma. Vox Sang (2001) 1.39
Recent advances in pathogenesis and management of hypereosinophilic syndromes. Allergy (2004) 1.38
Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice. J Immunol (1994) 1.37
Interleukin 10 prevents necrosis in murine experimental acute pancreatitis. Gastroenterology (1995) 1.37
Elective repair of groin hernias in the elderly. Br J Surg (1987) 1.36