Published in Cancer Res on April 01, 1982
On the mechanisms of induction of cancer-protective enzymes: a unifying proposal. Proc Natl Acad Sci U S A (1985) 2.19
Role of cytochrome P-450 and related enzymes in the pulmonary metabolism of xenobiotics. Environ Health Perspect (1984) 0.80
Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor. Hum Exp Toxicol (1996) 3.53
Wildtype Kras2 can inhibit lung carcinogenesis in mice. Nat Genet (2001) 3.27
A major lung cancer susceptibility locus maps to chromosome 6q23-25. Am J Hum Genet (2004) 3.05
A functional polymorphism of toll-like receptor 4 is not associated with likelihood or severity of meningococcal disease. J Infect Dis (2001) 2.27
Mechanism of action of beta-adrenergic receptor blocking agents in angina pectoris: comparison of action of propranolol with dexpropranolol and practolol. Br Med J (1969) 2.11
Giant left atrium as a cause of dysphagia. Ann Intern Med (1966) 2.10
Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist. Gastroenterology (1994) 2.05
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment. Science (1987) 2.03
The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypes. Osteoarthritis Cartilage (2006) 2.01
Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis. Ann Rheum Dis (2008) 2.01
Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse. Proc Natl Acad Sci U S A (1989) 1.95
A multi-site study using high-resolution HLA genotyping by next generation sequencing. Tissue Antigens (2011) 1.81
Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F1 mouse. Proc Natl Acad Sci U S A (1986) 1.60
Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res (1990) 1.57
Genetic variants in IL15 associate with progression of joint destruction in rheumatoid arthritis: a multicohort study. Ann Rheum Dis (2012) 1.56
Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study. Biochemistry (1994) 1.50
Comparison of breathing comfort during weaning with two ventilatory modes. Am J Respir Crit Care Med (1994) 1.47
Activating mutations of the c-Ha-ras protooncogene in chemically induced hepatomas of the male B6C3 F1 mouse. Proc Natl Acad Sci U S A (1986) 1.47
Implication of nonlinear kinetics on risk estimation in carcinogenesis. Science (1983) 1.45
The posteroanterior chest radiograph in depressed sternum. Clin Radiol (1989) 1.43
Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the A/J mouse. Cancer Res (1992) 1.42
Sarcoidosis in Caucasians, Blacks and Asians in London. Br J Dis Chest (1985) 1.40
The use of pharmacokinetics as an interpretive and predictive tool in chemical toxicology testing and risk assessment: a position paper on the appropriate use of pharmacokinetics in chemical toxicology. Regul Toxicol Pharmacol (1994) 1.39
Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogene in lung tumors from A/J mice treated with nitrosamines. Cancer Res (1989) 1.38
Conformationally defined neurotransmitter analogues. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer. J Med Chem (1991) 1.35
Simulation of the solution structure of the H-ras p21-GTP complex. Biochemistry (1992) 1.30
Atrioventricular and ventriculoatrial excitation in Wolff-Parkinson-White syndrome (type B). Temporary ablation at surgery. Circulation (1967) 1.28
Frequency of the Bcl-2/IgH rearrangement in normal individuals: implications for the monitoring of disease in patients with follicular lymphoma. J Clin Oncol (2001) 1.28
Prostaglandin removal and metabolism by isolated perfused rat lung. Prostaglandins (1976) 1.26
Alleviation of sleep maintenance insomnia with timed exposure to bright light. J Am Geriatr Soc (1993) 1.23
Accumulation of amines in the isolated perfused rabbit lung. J Pharmacol Exp Ther (1974) 1.23
A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat. Drug Metab Dispos (1977) 1.17
Effect on forearm arteries and veins of attenuation of the cardiac response to leg exercise. Clin Sci (1968) 1.17
Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma. Ann Oncol (2011) 1.15
Activation of the K-ras protooncogene in lung tumors from rats and mice chronically exposed to tetranitromethane. Cancer Res (1987) 1.15
Spinal sonography and magnetic resonance imaging in patients with repaired myelomeningocele: comparison of modalities. J Ultrasound Med (1999) 1.14
Xenobiotic accumulation and metabolism by isolated perfused rabbit lungs. J Pharmacol Exp Ther (1973) 1.14
Fractures on the chest radiograph in detection of alcoholic liver disease. Br Med J (Clin Res Ed) (1983) 1.13
A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population. Genes Immun (2011) 1.12
A prospective controlled study of diagnostic imaging for acute shin splints. Med Sci Sports Exerc (1998) 1.11
Autoantibodies in rheumatoid arthritis: a review. Biomed Pharmacother (2006) 1.10
Powassan virus: persistence of virus activity during 1966. Can Med Assoc J (1967) 1.09
Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review. BMC Cancer (2006) 1.09
Linkage analysis and the inheritance of arches in a Habbanite isolate. Am J Hum Genet (1979) 1.09
Characterization of p53 mutations in methylene chloride-induced lung tumors from B6C3F1 mice. Carcinogenesis (1993) 1.09
The distribution and excretion of 2,4,5,2',5'-pentachlorobiphenyl in the rat. Drug Metab Dispos (1975) 1.09
Fluoroscopy-guided sacroiliac joint injections. Radiology (2000) 1.08
A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin. Cancer Res (2000) 1.07
Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status. Arthritis Rheum (2007) 1.07
Perfusion lung scanning in obliterative pulmonary hypertension. Br Heart J (1973) 1.06
Toll-like receptors: their role in allergy and non-allergic inflammatory disease. Clin Exp Allergy (2002) 1.06
ADPase activity of isolated perfused rat lung. Life Sci (1978) 1.06
Expression and activity of ADAMTS-5 in synovium. Eur J Biochem (2001) 1.05
Activated protooncogenes in human lung tumors from smokers. Proc Natl Acad Sci U S A (1991) 1.05
Formation and persistence of benzo(a)pyrene metabolite-DNA adducts. Environ Health Perspect (1985) 1.05
Intravascular lipoma of the superior vena cava: CT features. J Comput Assist Tomogr (1994) 1.05
Effect of chlorination on the distribution and excretion of polychlorinated biphenyls. Drug Metab Dispos (1976) 1.03
Molecular dynamics simulation of HIV-1 protease in a crystalline environment and in solution. Biochemistry (1993) 1.03
Allelotype analysis of mouse lung carcinomas reveals frequent allelic losses on chromosome 4 and an association between allelic imbalances on chromosome 6 and K-ras activation. Cancer Res (1994) 1.03
The incidence of bacteremia following oral prophylaxis on pediatric patients. Oral Surg Oral Med Oral Pathol (1974) 1.02
Comparison of pulmonary O6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains. Mol Carcinog (1993) 1.01
Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse. Carcinogenesis (1991) 1.01
The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility. Proc Natl Acad Sci U S A (1994) 1.00
Mutational activation of the cellular Harvey ras oncogene in rat esophageal papillomas induced by methylbenzylnitrosamine. Cancer Res (1990) 1.00
Powassan virus: vernal spread during 1965. Can Med Assoc J (1966) 1.00
Use of stereoscopic x-ray pairs for measurements of airway length and diameter in situ. Br J Radiol (1972) 1.00
Articular hypermobility is a protective factor for hand osteoarthritis. Arthritis Rheum (2004) 0.99
Interaction between serotonin and efferent vagus nerves in dog lungs. J Appl Physiol Respir Environ Exerc Physiol (1978) 0.98
The radiology of aseptic cavitation in pulmonary infarction. Clin Radiol (1986) 0.98
Detection of activated proto-oncogenes in N-nitrosodiethylamine-induced liver tumors: a comparison between B6C3F1 mice and Fischer 344 rats. Carcinogenesis (1988) 0.97
Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride. Carcinogenesis (1993) 0.97
Allyl isothiocyanate: comparative disposition in rats and mice. Toxicol Appl Pharmacol (1984) 0.97
Proliferative lesions of the mouse lung: progression studies in strain A mice. Exp Lung Res (1991) 0.96
Chest radiography compared to laboratory markers in the detection of alcoholic liver disease. J R Coll Physicians Lond (1983) 0.96
No independent association between a tumor necrosis factor-alpha promotor region polymorphism and insulin-dependent diabetes mellitus. Eur J Immunol (1993) 0.96
Cell selective alkylation of DNA in rat lung following low dose exposure to the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res (1987) 0.96
Genetic influences modulating the radiological severity of rheumatoid arthritis. Ann Rheum Dis (2010) 0.96
Bone contusions of the posterior lip of the medial tibial plateau (contrecoup injury) and associated internal derangements of the knee at MR imaging. Radiology (1999) 0.95
Clearance of recombinant tissue factor pathway inhibitor (TFPI) in rabbits. Thromb Haemost (1992) 0.95
A biologically important single nucleotide polymorphism within the toll-like receptor-4 gene is not associated with rheumatoid arthritis. Clin Exp Rheumatol (2003) 0.95
A susceptibility region for myasthenia gravis extending into the HLA-class I sector telomeric to HLA-C. Hum Immunol (1999) 0.94
Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene. Cancer Res (1997) 0.94
A gain of function polymorphism in the interleukin 6 receptor influences RA susceptibility. Ann Rheum Dis (2009) 0.94
Comparison of the pharmacokinetics of several polychlorinated biphenyls in mouse, rat, dog, and monkey by means of a physiological pharmacokinetic model. Drug Metab Dispos (1985) 0.94
Optimization of cryopreservation procedures for rat and human hepatocytes. Xenobiotica (1989) 0.94
Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors. Carcinogenesis (1993) 0.94
Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). J Magn Reson Imaging (2000) 0.93
Role of Clara cells and type II cells in the development of pulmonary tumors in rats and mice following exposure to a tobacco-specific nitrosamine. Exp Lung Res (1991) 0.93
Effect of varying exposure regimens on methylene chloride-induced lung and liver tumors in female B6C3F1 mice. Carcinogenesis (1993) 0.92
Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine. Carcinogenesis (1992) 0.92
Inhalation exposure to a hepatocarcinogenic concentration of methylene chloride does not induce sustained replicative DNA synthesis in hepatocytes of female B6C3F1 mice. Carcinogenesis (1993) 0.92
Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging. J Magn Reson Imaging (2000) 0.92
An evaluation of the carcinogenic potential of the herbicide alachlor to man. Hum Exp Toxicol (1999) 0.91
Notch4, a non-HLA gene in the MHC is strongly associated with the most severe form of alopecia areata. Hum Genet (2003) 0.91
Toll-like receptor (TLR) 4 polymorphisms and COPD. Thorax (2004) 0.91
Chain length dependency of fatty acid and carbamate binding to serum albumin. Biochem Pharmacol (1982) 0.90
Rapid progression of fibrosing alveolitis and thyrotoxicosis after antithymocyte globulin therapy for aplastic anemia. Ann Hematol (1995) 0.90
Structural requirements for, and the effects of chemicals on, the rat pulmonary inactivation of prostaglandins. Prostaglandins (1977) 0.90