Published in Toxicol Appl Pharmacol on April 01, 1981
Toxicological characterization of phthalic Acid. Toxicol Res (2011) 0.76
Chemically induced urolithiasis in weanling rats. Am J Pathol (1982) 0.75
A critical review of the literature on hydrogen sulfide toxicity. Crit Rev Toxicol (1984) 3.57
The resolution of some steps of the reactions of lactate dehydrogenase with its substrates. Biochem J (1968) 1.62
The developmental toxicity of bisphenol A in rats and mice. Fundam Appl Toxicol (1987) 1.57
O4-ethyldeoxythymidine, but not O6-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine. Proc Natl Acad Sci U S A (1984) 1.54
Reproductive toxicity of sulfamethazine in Swiss CD-1 mice during continuous breeding. Fundam Appl Toxicol (1992) 1.39
A critical review of the literature on acrolein toxicity. Crit Rev Toxicol (1985) 1.31
The developmental toxicity of ethylene glycol in rats and mice. Toxicol Appl Pharmacol (1985) 1.27
Comparative morphometry of the nasal cavity in rats and mice. J Anat (1982) 1.27
A critical review of the literature on carbon disulfide toxicity. Crit Rev Toxicol (1983) 1.24
Dinitrotoluene: acute toxicity, oncogenicity, genotoxicity, and metabolism. Crit Rev Toxicol (1984) 1.21
Formaldehyde (CH2O) concentrations in the blood of humans and Fischer-344 rats exposed to CH2O under controlled conditions. Am Ind Hyg Assoc J (1985) 1.20
Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: pharmacokinetics, rat-to-monkey interspecies scaling, and extrapolation to man. Fundam Appl Toxicol (1991) 1.15
Differentiation between metabolic incorporation and covalent binding in the labeling of macromolecules in the rat nasal mucosa and bone marrow by inhaled [14C]- and [3H]formaldehyde. Toxicol Appl Pharmacol (1984) 1.14
Statistical theory of cooperative binding to proteins. The Hill equation and the binding potential. J Am Chem Soc (1971) 1.12
Differences between the promoting activities of the peroxisome proliferator WY-14,643 and phenobarbital in rat liver. Cancer Res (1989) 1.11
Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium. Fundam Appl Toxicol (1991) 1.08
Serum gamma glutamyl transferase as a specific indicator of bile duct lesions in the rat liver. Am J Pathol (1984) 1.08
Ultrastructural characterization of the nasal respiratory epithelium in the rat. Am J Anat (1984) 1.01
Perspectives on the mechanism of action of the splenic toxicity of aniline and structurally-related compounds. Food Chem Toxicol (1987) 1.00
The induction of bladder stones by terephthalic acid, dimethyl terephthalate, and melamine (2,4,6-triamino-s-triazine) and its relevance to risk assessment. Regul Toxicol Pharmacol (1985) 1.00
alpha-Naphthylisothiocyanate induced alterations in hepatic drug metabolizing enzymes and liver morphology: implications concerning anticarcinogenesis. Carcinogenesis (1981) 0.99
A general derivation of the binding potential. J Mol Biol (1970) 0.98
Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans? Regul Toxicol Pharmacol (1998) 0.98
Carcinogenicity of inhaled benzene in CBA mice. Fundam Appl Toxicol (1993) 0.97
Carcinogenicity and toxicity of inhaled nitrobenzene in B6C3F1 mice and F344 and CD rats. Fundam Appl Toxicol (1994) 0.96
Potential role of alpha-2 mu-globulin, protein droplet accumulation, and cell replication in the renal carcinogenicity of rats exposed to trichloroethylene, perchloroethylene, and pentachloroethane. Toxicol Appl Pharmacol (1988) 0.95
A review of adverse pregnancy outcomes and formaldehyde exposure in human and animal studies. Regul Toxicol Pharmacol (2001) 0.95
p53 gene mutation in thyroid carcinoma. Cancer Lett (1996) 0.93
Evaluation of genotoxicity, pathological lesions, and cell proliferation in livers of rats and mice treated with furan. Environ Mol Mutagen (1992) 0.93
Mitogenic stimulation of hepatocellular proliferation in rodents following 1,4-dichlorobenzene administration. Carcinogenesis (1992) 0.92
Effects of formaldehyde exposure on the extractability of DNA from proteins in the rat nasal mucosa. Toxicol Appl Pharmacol (1983) 0.92
Myelolipomas of the liver in a domestic cat. J Am Vet Med Assoc (1971) 0.92
Determination of formaldehyde in biological tissues by gas chromatography/mass spectrometry. Biomed Mass Spectrom (1982) 0.90
Ultrastructures of atypical acinar cell nodules in rat pancreas induced by 4-hydroxyaminoquinoline-1-oxide. Lab Invest (1976) 0.89
Formaldehyde concentrations in the blood of rhesus monkeys after inhalation exposure. Food Chem Toxicol (1988) 0.89
Eumycotic mycetoma in a dog caused by Allescheria boydii. J Am Vet Med Assoc (1970) 0.89
Correlation of O4-ethyldeoxythymidine accumulation, hepatic initiation and hepatocellular carcinoma induction in rats continuously administered diethylnitrosamine. Carcinogenesis (1986) 0.88
Dinitrotoluene isomer-specific hepatocarcinogenesis in F344 rats. J Natl Cancer Inst (1987) 0.88
Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643. Carcinogenesis (1989) 0.87
Effect of size on portal circulation of hepatic nodules from carcinogen-treated rats. Cancer Res (1983) 0.87
Comparison of hepatic carcinogen initiation-promotion systems. Carcinogenesis (1982) 0.86
Lysine residues 162 and 340 are involved in the catalysis and coenzyme binding of NADP(+)-dependent malic enzyme from pigeon. Biochem Biophys Res Commun (2000) 0.86
Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator WY-14,643 in rat liver. Carcinogenesis (1991) 0.86
Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation. Am J Pathol (1989) 0.85
Biochemical and morphologic studies of heterogeneous lobe responses in hepatocarcinogenesis. Carcinogenesis (1986) 0.85
Development of hepatic lesions in male Fischer-344 rats fed AIN-76A purified diet. Toxicol Appl Pharmacol (1982) 0.85
beta-Naphthylisothiocyanate-induced alterations in hepatic drug metabolism and liver morphology. Toxicol Appl Pharmacol (1981) 0.85
Non-linear biological responses to formaldehyde and their implications for carcinogenic risk assessment. Carcinogenesis (1983) 0.84
Quantification of renal uric acid synthesis in the rat. Am J Physiol (1980) 0.84
Effects of methapyrilene on rat hepatic xenobiotic metabolizing enzymes and liver morphology. Fundam Appl Toxicol (1985) 0.84
Developmental toxicity evaluation of methyl tertiary-butyl ether (MTBE) by inhalation in mice and rabbits. J Appl Toxicol (1997) 0.84
Ultrastructural evaluation of acute nasal toxicity in the rat respiratory epithelium in response to formaldehyde gas. Fundam Appl Toxicol (1986) 0.83
Effect on the expression of c-met, c-myc and PPAR-alpha in liver and liver tumors from rats chronically exposed to the hepatocarcinogenic peroxisome proliferator WY-14,643. Carcinogenesis (1996) 0.83
Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation. Biochim Biophys Acta (1992) 0.83
Dose-related effects of the hepatocarcinogen, Wy-14,643, on peroxisomes and cell replication. Fundam Appl Toxicol (1992) 0.83
Relationship between hepatocyte necrosis, proliferation, and initiation induced by diethylnitrosamine in the male F344 rat. Fundam Appl Toxicol (1993) 0.83
Lack of genotoxic activity of di(2-ethylhexyl)phthalate (DEHP) in rat and human hepatocytes. Carcinogenesis (1984) 0.82
Microcirculation in periportal and pericentral regions of lobule in perfused rat liver. Am J Physiol (1985) 0.82
Covalent binding of inhaled formaldehyde to DNA in the nasal mucosa of Fischer 344 rats: analysis of formaldehyde and DNA by high-performance liquid chromatography and provisional pharmacokinetic interpretation. Fundam Appl Toxicol (1989) 0.82
Decreased extractability of DNA from proteins in the rat nasal mucosa after acetaldehyde exposure. Fundam Appl Toxicol (1986) 0.82
Oxidation of formaldehyde and acetaldehyde by NAD+-dependent dehydrogenases in rat nasal mucosal homogenates. Biochem Pharmacol (1984) 0.82
Effects of lactational administration of acrylamide on rat dams and offspring. Reprod Toxicol (2000) 0.81
Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643. Carcinogenesis (1994) 0.81
Two-generation reproductive toxicity study of methyl tertiary-butyl ether (MTBE) in rats. J Appl Toxicol (1997) 0.81
Guidelines for measuring chemically induced cell proliferation in specific rodent target organs. Prog Clin Biol Res (1991) 0.81
Trypan blue uptake as a new method to investigate hepatotoxicity in periportal and pericentral regions of the liver lobule: studies with allyl alcohol in the perfused liver. J Pharmacol Exp Ther (1984) 0.81
Chemically induced cell proliferation in carcinogenesis. IARC Sci Publ (1992) 0.81
Contrasting hepatocytic peroxisome proliferation, lipofuscin accumulation and cell turnover for the hepatocarcinogens Wy-14,643 and clofibric acid. Carcinogenesis (1992) 0.81
Mouse liver carcinogenesis: mechanisms and relevance. Fundam Appl Toxicol (1991) 0.80
Histochemical localization of formaldehyde dehydrogenase in the rat. Toxicol Appl Pharmacol (1990) 0.80
A stable isotope method for measurement of thymidine incorporation into DNA. Cell Tissue Kinet (1977) 0.80
Inhibition of dimethylnitrosamine-induced strand breaks in liver DNA and liver cell necrosis by diethyldithiocarbamate. J Natl Cancer Inst (1977) 0.80
Effect of regeneration and hyperplasia on levels of DNA base oxidation in rat liver. Cancer Lett (1993) 0.80
The reproductive and developmental toxicity of the antifungal drug Nyotran (liposomal nystatin) in rats and rabbits. Toxicol Sci (2000) 0.80
Inter-laboratory control data for reproductive endpoints required in the OPPTS 870.3800/OECD 416 reproduction and fertility test. Birth Defects Res B Dev Reprod Toxicol (2009) 0.80
Effect of peroxisome proliferator carcinogens on unscheduled DNA synthesis in rat hepatocytes determined by autoradiography. Cancer Lett (1986) 0.79
Pancreatic acinar cell damage induced by 4-nitroquinoline-1-oxide and 4-hydroxyaminoquinoline-1-oxide. J Natl Cancer Inst (1974) 0.79
Dichloromethane metabolism to formaldehyde and reaction of formaldehyde with nucleic acids in hepatocytes of rodents and humans with and without glutathione S-transferase T1 and M1 genes. Fundam Appl Toxicol (1997) 0.79
The nongenotoxic hepatocarcinogen Wy-14,643 is an uncoupler of oxidative phosphorylation in vivo. Toxicol Appl Pharmacol (1993) 0.79
Perinatal toxicity and metabolism of n-hexane in Fischer-344 rats after inhalation exposure during gestation. Toxicol Appl Pharmacol (1979) 0.79
p53 gene mutation in cerebral primitive neuroectodermal tumor in Taiwan. Cancer Lett (1996) 0.79
Chemically induced cell proliferation in liver carcinogenesis. Prog Clin Biol Res (1991) 0.79
Surface topography and distribution of cell types in the rat nasal respiratory epithelium: scanning electron microscopic observations. Am J Anat (1984) 0.79
The protective effects of diethyldithiocarbamate and cycloheximide on the multiple hepatic lesions induced by carbon tetrachloride in the rat. Toxicol Appl Pharmacol (1978) 0.79
Microcirculation of hepatic nodules from diethylnitrosamine-treated rats. Cancer Res (1985) 0.79
Quantitative evaluation of hepatic foci of cellular alteration occurring spontaneously in Fischer-344 rats. Fundam Appl Toxicol (1985) 0.79
Depletion of nasal mucosal glutathione by acrolein and enhancement of formaldehyde-induced DNA-protein cross-linking by simultaneous exposure to acrolein. Arch Toxicol (1985) 0.79
Dinitrotoluene structure-dependent initiation of hepatocytes in vivo. Carcinogenesis (1983) 0.79
Two-year inhalation exposure of female and male B6C3F1 mice and F344 rats to chlorine gas induces lesions confined to the nose. Fundam Appl Toxicol (1995) 0.79
TGF alpha differentially expressed in liver foci induced by diethylnitrosamine initiation and peroxisome proliferator promotion. Carcinogenesis (1995) 0.79
Chlorinated hydrocarbon-induced peroxisomal enzyme activity in relation to species and organ carcinogenicity. Toxicol Appl Pharmacol (1987) 0.78
Promotion of hepatocellular foci in female rats by chenodeoxycholic acid. Carcinogenesis (1991) 0.78
Failure of the peroxisome proliferator WY-14,643 to induce unscheduled DNA synthesis in rat hepatocytes following in vivo treatment. Carcinogenesis (1988) 0.78
Carcinogen treatment increases glutathione hydrolysis by gamma-glutamyl transpeptidase. Carcinogenesis (1987) 0.78
Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice. Fundam Appl Toxicol (1995) 0.78
Retrospective assessment of liver cell proliferation via PCNA: a comparison with tritiated thymidine. Cancer Lett (1994) 0.78