Published in Br J Pharmacol on July 01, 1981
Antagonism of the thromboxane-sensitive contractile systems of the rabbit aorta, dog saphenous vein and guinea-pig trachea. Br J Pharmacol (1982) 2.10
Prostaglandin E receptor subtypes in smooth muscle: agonist activities of stable prostacyclin analogues. Br J Pharmacol (1986) 1.98
Characterization of prostanoid relaxant/inhibitory receptors (psi) using a highly selective agonist, TR4979. Br J Pharmacol (1986) 1.92
Further characterization of the 5-HT receptor mediating vascular relaxation and elevation of cyclic AMP in porcine isolated vena cava. Br J Pharmacol (1989) 1.39
Thromboxane-induced phosphatidate formation in human platelets. Relationship to receptor occupancy and to changes in cytosolic free calcium. Biochem J (1984) 1.39
Effects of prostaglandins and thromboxane analogues on bullock and dog iris sphincter preparations. Br J Pharmacol (1982) 1.33
Influence of the vascular endothelium on agonist-induced contractions and relaxations in rat aorta. Br J Pharmacol (1986) 1.26
Prostanoid-induced contraction of human bronchial smooth muscle is mediated by TP-receptors. Br J Pharmacol (1989) 1.20
The action of prostanoid receptor agonists and antagonists on smooth muscle and platelets. Br J Pharmacol (1988) 1.16
Evaluation of the bronchodilator properties of Ro 31-6930, a novel potassium channel opener, in the guinea-pig. Br J Pharmacol (1990) 1.15
Function, mechanism and evolution of the moubatin-clade of soft tick lipocalins. Insect Biochem Mol Biol (2008) 1.11
Prostaglandin D2 interacts at thromboxane receptor-sites on guinea-pig platelets. Br J Pharmacol (1986) 1.05
Characterization of prostanoid receptors mediating contraction of the gastric fundus and ileum: studies using mice deficient in prostanoid receptors. Br J Pharmacol (2000) 1.04
Responsiveness of platelets and coronary arteries from different species to synthetic thromboxane and prostaglandin endoperoxide analogues. Br J Pharmacol (1983) 1.03
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Characterization of prostanoid receptors mediating actions of the isoprostanes, 8-iso-PGE(2) and 8-iso-PGF(2alpha), in some isolated smooth muscle preparations. Br J Pharmacol (2000) 0.96
BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro. Br J Pharmacol (1991) 0.95
Role of endoperoxides in arachidonic acid-induced vasoconstriction in the isolated perfused kidney of the rat. Br J Pharmacol (1989) 0.93
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Effect of platelet agonists on airway reactivity and intrathoracic platelet accumulation. Br J Pharmacol (1987) 0.92
Bradykinin-induced vasoconstriction of rat mesenteric arteries precontracted with noradrenaline. Br J Pharmacol (1990) 0.91
Aggregating platelets contract isolated canine pulmonary arteries by releasing 5-hydroxytryptamine. J Clin Invest (1984) 0.90
Regulation of thromboxane receptor activation in human platelets. Proc Natl Acad Sci U S A (1989) 0.88
Characterization of the prostanoid receptor profile of enprostil and isomers in smooth muscle and platelets in vitro. Br J Pharmacol (1989) 0.88
Localisation of thromboxane A2 receptors and the corresponding mRNAs in human eye tissue. Br J Ophthalmol (1994) 0.87
Effects of endogenous and synthetic prostanoids, the thromboxane A2 receptor agonist U-46619 and arachidonic acid on [3H]-noradrenaline release and vascular tone in rat isolated kidney. Br J Pharmacol (1989) 0.86
Protein kinase G regulates the basal tension and plays a major role in nitrovasodilator-induced relaxation of porcine coronary veins. Br J Pharmacol (2007) 0.85
Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets. Biochem J (2006) 0.83
Pharmacological effects of (+/-)-11-deoxy, 16-phenoxy-prostaglandin E1 derivatives in the cardiovascular system. Br J Pharmacol (1985) 0.83
Thromboxane receptor signaling is required for fibronectin-induced matrix metalloproteinase 9 production by human and murine macrophages and is attenuated by the Arhgef1 molecule. J Biol Chem (2011) 0.83
Arachidonic acid metabolites follow the preferential course of cyclooxygenase pathway for the basal tone in the internal anal sphincter. Am J Physiol Gastrointest Liver Physiol (2009) 0.81
Effect of the specific thromboxane receptor blocking drug AH23848 in patients with angina pectoris. Br Heart J (1986) 0.81
Binding of thromboxane A2/prostaglandin H2 agonists to human platelets. Br J Pharmacol (1987) 0.81
Evidence for human thromboxane receptor heterogeneity using a novel series of 9,11-cyclic carbonate derivatives of prostaglandin F2 alpha. Br J Pharmacol (1996) 0.80
The effects of the stable thromboxane A2-mimetic, U46619, on gastric mucosal damage and gastric non-parietal secretion in the rat. Br J Pharmacol (1987) 0.80
Nature of extracellular signal that triggers RhoA/ROCK activation for the basal internal anal sphincter tone in humans. Am J Physiol Gastrointest Liver Physiol (2015) 0.80
Heterogeneity in relaxation of different sized porcine coronary arteries to nitrovasodilators: role of PKG and MYPT1. Pflugers Arch (2011) 0.80
Pharmacological characterization of prostanoid receptors mediating vasoconstriction in human umbilical vein. Br J Pharmacol (2003) 0.80
Liver kinase B1 is required for thromboxane receptor-dependent nuclear factor-κB activation and inflammatory responses. Arterioscler Thromb Vasc Biol (2013) 0.79
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NP-184[2-(5-methyl-2-furyl) benzimidazole], a novel orally active antithrombotic agent with dual antiplatelet and anticoagulant activities. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.77
Effect of an inhaled thromboxane mimetic (U46619) on in vivo pulmonary resistance and airway hyperresponsiveness in dogs. J Physiol (1992) 0.77
Mediation of bradykinin-induced contraction in canine veins via thromboxane/prostaglandin endoperoxide receptor activation. Br J Pharmacol (1990) 0.77
Involvement of thromboxane a(2) in the modulation of pacemaker activity of interstitial cells of cajal of mouse intestine. Korean J Physiol Pharmacol (2008) 0.77
Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. Br J Pharmacol (2010) 0.77
Effects of vasoactive intestinal polypeptide on antigen-induced bronchoconstriction and thromboxane release in guinea-pig lung. Br J Pharmacol (1993) 0.77
IgE-dependent activation of alveolar macrophages augments neurally mediated contraction of small airways. Br J Pharmacol (1991) 0.77
Investigation of the contributions of nitric oxide and prostaglandins to the actions of endothelins and sarafotoxin 6c in rat isolated perfused lungs. Br J Pharmacol (1996) 0.77
Nitric oxide limits the eicosanoid-dependent bronchoconstriction and hypotension induced by endothelin-1 in the guinea-pig. Br J Pharmacol (1999) 0.77
Hemoglobin infusion does not alter murine pulmonary vascular tone. Nitric Oxide (2013) 0.76
Selective inhibition of thromboxane B2 accumulation and metabolism in perfused guinea-pig lung. Br J Pharmacol (1983) 0.76
Proceedings of the British Pharmacological Society. University of Southampton, 17th-19th July 1985. Abstracts. Br J Pharmacol (1985) 0.75
Sir David Jack: an extraordinary drug discoverer and developer. Br J Clin Pharmacol (2013) 0.75
A study of the capacity of various eicosanoids to stimulate skeletal muscle formation in chicken embryos. J Anat (1991) 0.75
Individual variations of prostanoid agonist responses in rabbit aorta: evidence for the independent regulation of prostanoid receptor subtypes. Br J Pharmacol (1987) 0.75
Classification of prostaglandin receptors based on coupling to signal transduction systems. Biochem J (1989) 0.75
Proceedings of the British Pharmacological Society. Nottingham, 7th-9th September 1988. Abstracts. Br J Pharmacol (1988) 0.75
Proceedings of the British Pharmacological Society, University of Cambridge, 6th-8th April, 1983. Abstracts. Br J Pharmacol (1983) 0.75
Proceedings of the British Pharmacological Society. Leeds, 12th-14th July 1989. Abstracts. Br J Pharmacol (1989) 0.75
A sensitive method for the assay of 5-hydroxytryptamine. Br J Pharmacol Chemother (1957) 17.22
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 10.82
THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD. Br J Pharmacol Chemother (1964) 9.77
Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs. J Pharmacol Exp Ther (1953) 8.48
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci U S A (1974) 7.00
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Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. Proc Natl Acad Sci U S A (1973) 4.43
Receptors for 5-hydroxytryptamine and noradrenaline in rabbit isolated ear artery and aorta. Br J Pharmacol (1976) 3.95
The cat lung strip as an in vitro preparation of peripheral airways: a comparison of beta-adrenoceptor agonists, autacoids and anaphylactic challenge on the lung strip and trachea. Br J Pharmacol (1976) 3.04
Evidence for nonadrenergic inhibitory nerves in the guinea pig trachealis muscle. Am J Physiol (1973) 2.91
Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid. Prostaglandins (1977) 2.67
Imidazole: a selective inhibitor of thromboxane synthetase. Prostaglandins (1977) 2.48
A COMPARISON OF THE ACTIONS OF PROSTAGLANDINS F2-ALPHA AND E1 ON SMOOTH MUSCLE. Br J Pharmacol Chemother (1965) 2.22
The effects of prostagladin endoperoxides and thromboxane A2 on strips of rabbit coeliac artery and certain other smooth muscle preparations [proceedings]. Br J Pharmacol (1976) 2.06
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Thromboxane A2: effects on airway and vascular smooth muscle. Prostaglandins (1977) 1.82
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Some biological effects of prostaglandin endoperoxide analogs. Life Sci (1976) 1.40
Prostaglandins H1 and H2. Convenient biochemical synthesis and isolation. Further biological and spectroscopic characterization. Prostaglandins (1977) 1.40
U-46619, a selective thromboxane A2-like agonist? [proceedings]. Br J Pharmacol (1980) 1.28
The effects of uptake1 on alpha-adrenoceptor antagonist potency in dog saphenous vein. Br J Pharmacol (1978) 1.19
Activity of prostaglandin E, F, A and B on sphincter, dilator and ciliary muscle preparations of the cat eye. Prostaglandins (1975) 1.10
The cat isolated trachea, a useful preparation for the study of the smooth muscle relaxant action of prostaglandins [proceedings]. Br J Pharmacol (1979) 1.01
9,11-epoxyiminoprosta-5,13-dienoic acid is a thromboxane A2 antagonist in human platelets. Nature (1978) 1.00
Trimethoquinol is a potent prostaglandin endoperoxide antagonist [proceedings]. Br J Pharmacol (1978) 0.86
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Pharmacology of AH 5158; a drug which blocks both - and -adrenoceptors. Br J Pharmacol (1972) 4.53
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Receptors for 5-hydroxytryptamine and noradrenaline in rabbit isolated ear artery and aorta. Br J Pharmacol (1976) 3.95
Salbutamol: a new, selective beta-adrenoceptive receptor stimulant. Br J Pharmacol (1969) 3.86
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Studies on the characterisation of prostanoid receptors: a proposed classification. Prostaglandins (1982) 2.73
A new preparation of the isolated intact trachea of the guinea-pig. J Pharm Pharmacol (1970) 2.58
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GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro. Br J Pharmacol (1989) 2.39
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Comparison of the bronchodilator and cardiovascular actions of salbutamol, isoprenaline and orciprenaline in guinea-pigs and dogs. Br J Pharmacol (1971) 2.27
An immunochemical characterization of the phytochrome destruction reaction. Biochim Biophys Acta (1974) 2.20
A comparison of 5-hydroxytryptamine receptors mediating contraction in rabbit aorta and dog saphenous vein: evidence for different receptor types obtained by use of selective agonists and antagonists. Br J Pharmacol (1985) 2.06
Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction. Biochemistry (1999) 2.04
Reversible redistribution of phytochrome within the cell upon conversion to its physiologically active form. Proc Natl Acad Sci U S A (1975) 2.01
A non-adrenergic inhibitory nervous pathway in guinea-pig trachea. Br J Pharmacol (1974) 1.97
The inducement of tone and its inhibition in isolated tracheal muscle. J Pharm Pharmacol (1971) 1.95
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Evidence for two types of excitatory receptor for 5-hydroxytryptamine in dog isolated vasculature. Br J Pharmacol (1980) 1.86
AH6809, a prostaglandin DP-receptor blocking drug on human platelets. Br J Pharmacol (1988) 1.82
Electrophysiological properties of P2X-purinoceptors in rat superior cervical, nodose and guinea-pig coeliac neurones. J Physiol (1995) 1.79
Effects of some purine derivatives on the guinea-pig trachea and their interaction with drugs that block adenosine uptake. Br J Pharmacol (1976) 1.77
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Combined alpha- and beta-adrenoceptor blocking drug AH 5158: further studies on alpha-adrenoceptor blockade in anaesthetized animals. Br J Pharmacol (1975) 1.72
Two types of excitatory receptor for 5-hydroxytryptamine in dog vasculature? [proceedings]. Br J Pharmacol (1977) 1.67
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Expression and characterization of recombinant rat Acyl-CoA synthetases 1, 4, and 5. Selective inhibition by triacsin C and thiazolidinediones. J Biol Chem (2001) 1.64
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Electron microscopic localization of phytochrome in plants using an indirect antibody-labeling method. J Histochem Cytochem (1974) 1.47
Acute nociception mediated by hindpaw P2X receptor activation in the rat. Br J Pharmacol (1997) 1.46
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Renal disease in type I glycogen storage disease. N Engl J Med (1988) 1.45
International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. IX. Recommendations on terms and symbols in quantitative pharmacology. Pharmacol Rev (1995) 1.45
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A method for quantitating platelet aggregation and analyzing drug-receptor interactions on platelets in whole blood in vitro. J Pharmacol Methods (1981) 1.39
Further characterization of the 5-HT receptor mediating vascular relaxation and elevation of cyclic AMP in porcine isolated vena cava. Br J Pharmacol (1989) 1.39
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New evidence with selective agonists and antagonists for the subclassification of PGE2-sensitive (EP) receptors. Adv Prostaglandin Thromboxane Leukot Res (1987) 1.35
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Pharmacological characterization of ATP- and LPS-induced IL-1beta release in human monocytes. Br J Pharmacol (1999) 1.34
A comparison of the beta-adrenoreceptor stimulant properties of isoprenaline, with those of orciprenaline, salbutamol, soterenol and trimetoquinol on isolated atria and trachea of the guinea pig. J Pharm Pharmacol (1970) 1.34
The donation and transplantation of kidneys: should the law be changed? J Med Ethics (1979) 1.32
5-HT1-like receptors mediate 5-hydroxytryptamine-induced contraction of human isolated basilar artery. Br J Pharmacol (1989) 1.31
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Contractile and relaxant actions of prostaglandins on guinea-pig isolated trachea. Br J Pharmacol (1980) 1.25