K J Breslauer

Author PubWeight™ 146.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Predicting DNA duplex stability from the base sequence. Proc Natl Acad Sci U S A 1986 21.73
2 Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves. Biopolymers 1987 6.96
3 Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution. Biochemistry 1982 3.76
4 Salt-dependent conformational transitions in the self-complementary deoxydodecanucleotide d(CGCAATTCGCG): evidence for hairpin formation. Biopolymers 1983 3.44
5 Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution. Biochemistry 1982 3.30
6 Thermodynamics of (dG--dC)3 double-helix formation in water and deuterium oxide. Biochemistry 1981 3.30
7 Extra adenosine stacks into the self-complementary d(CGCAGAATTCGCG) duplex in solution. Biochemistry 1982 3.02
8 Calorimetric and spectroscopic investigation of the helix-to-coil transition of a ribo-oligonucleotide: rA7U7. J Mol Biol 1975 2.84
9 Influence of loop residues on the relative stabilities of DNA hairpin structures. Proc Natl Acad Sci U S A 1988 2.37
10 Calorimetric determination of base-stacking enthalpies in double-helical DNA molecules. Biopolymers 1982 2.36
11 Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: a spectroscopic and calorimetric study. Proc Natl Acad Sci U S A 1990 2.18
12 Influence of dangling thymidine residues on the stability and structure of two DNA duplexes. Biochemistry 1988 2.16
13 A more unified picture for the thermodynamics of nucleic acid duplex melting: a characterization by calorimetric and volumetric techniques. Proc Natl Acad Sci U S A 1999 2.16
14 Influence of the oxidatively damaged adduct 8-oxodeoxyguanosine on the conformation, energetics, and thermodynamic stability of a DNA duplex. Biochemistry 1995 2.09
15 Thermodynamics and structure of a DNA tetraplex: a spectroscopic and calorimetric study of the tetramolecular complexes of d(TG3T) and d(TG3T2G3T). Proc Natl Acad Sci U S A 1992 2.03
16 Calorimetric and spectroscopic investigation of drug-DNA interactions. I. The binding of netropsin to poly d(AT). Nucleic Acids Res 1983 1.96
17 Spectroscopic and calorimetric characterizations of DNA duplexes containing 2-aminopurine. Biochemistry 1996 1.88
18 Effect of tetramethylammonium ion on the helix-to-coil transition of poly(deoxyadenylylthymidine): a nuclear magnetic resonance and calorimetric investigation. Biochemistry 1981 1.83
19 Origins of netropsin binding affinity and specificity: correlations of thermodynamic and structural data. Proc Natl Acad Sci U S A 1987 1.83
20 Tetraplex formation of a guanine-containing nonameric DNA fragment. Science 1990 1.75
21 Calorimetric and spectroscopic investigation of the helix-to-coil transition of the self-complementary deoxyribonucleotide ATGCAT. Biophys Chem 1981 1.67
22 Structure and energetics of a hexanucleotide duplex with stacked trinucleotide ends formed by the sequence d(GAATTCGCG). Biochemistry 1982 1.53
23 Thermodynamic characterization of daunomycin-DNA interactions: comparison of complete binding profiles for a series of DNA host duplexes. Biochemistry 1993 1.47
24 Thermodynamic consequences of an abasic lesion in duplex DNA are strongly dependent on base sequence. Biochemistry 1998 1.44
25 The contribution of DNA single-stranded order to the thermodynamics of duplex formation. Proc Natl Acad Sci U S A 1991 1.43
26 Melting behavior of a covalently closed, single-stranded, circular DNA. Biochemistry 1989 1.37
27 Solvent effects on the kinetics and thermodynamics of stacking in poly(cytidylic acid). Biochemistry 1981 1.36
28 Influence of abasic and anucleosidic sites on the stability, conformation, and melting behavior of a DNA duplex: correlations of thermodynamic and structural data. Proc Natl Acad Sci U S A 1989 1.31
29 Physical studies of DNA premelting equilibria in duplexes with and without homo dA.dT tracts: correlations with DNA bending. Biochemistry 1990 1.30
30 Thermodynamics of drug-DNA interactions. J Biomol Struct Dyn 1983 1.22
31 Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proc Natl Acad Sci U S A 1996 1.20
32 Binding of a hairpin polyamide in the minor groove of DNA: sequence-specific enthalpic discrimination. Proc Natl Acad Sci U S A 1996 1.18
33 Thermodynamics of an intramolecular DNA triple helix: a calorimetric and spectroscopic study of the pH and salt dependence of thermally induced structural transitions. J Mol Biol 1995 1.18
34 Characterization of the minor groove environment in a drug-DNA complex: bisbenzimide bound to the poly[d(AT)].poly[d(AT)]duplex. Proc Natl Acad Sci U S A 1988 1.16
35 Nucleic acid hybridization: triplex stability and energetics. Annu Rev Biophys Biomol Struct 1995 1.15
36 The melting behavior of a DNA junction structure: a calorimetric and spectroscopic study. Biopolymers 1987 1.14
37 Characterization by 1H NMR of glycosidic conformations in the tetramolecular complex formed by d(GGTTTTTGG). Nucleic Acids Res 1991 1.14
38 Influence of drug binding on DNA hydration: acoustic and densimetric characterizations of netropsin binding to the poly(dAdT).poly(dAdT) and poly(dA).poly(dT) duplexes and the poly(dT).poly(dA).poly(dT) triplex at 25 degrees C. Biochemistry 1994 1.12
39 Binding of actinomycin D to DNA: evidence for a nonclassical high-affinity binding mode that does not require GpC sites. Proc Natl Acad Sci U S A 1989 1.10
40 Influence of base composition, base sequence, and duplex structure on DNA hydration: apparent molar volumes and apparent molar adiabatic compressibilities of synthetic and natural DNA duplexes at 25 degrees C. Biochemistry 1994 1.08
41 The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA. Biochemistry 1999 1.07
42 Thermodynamics and premelting conformational changes of phased (dA)5 tracts. Biochemistry 1993 1.07
43 Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix. Proc Natl Acad Sci U S A 1992 1.05
44 Hydration and partial compressibility of biological compounds. Biophys Chem 1994 1.04
45 Comparative spectroscopic, calorimetric, and computational studies of nucleic acid complexes with 2',5"-versus 3',5"-phosphodiester linkages. Proc Natl Acad Sci U S A 1993 1.02
46 The thermodynamics of drug-DNA interactions: ethidium bromide and propidium iodide. J Biomol Struct Dyn 1987 1.02
47 Polyamine-linked oligonucleotides for DNA triple helix formation. Nucleic Acids Res 1993 1.01
48 A spectroscopic and calorimetric study of the melting behaviors of a "bent" and a "normal" DNA duplex: [d(GA4T4C)]2 versus [d(GT4A4C)]2. Proc Natl Acad Sci U S A 1991 1.01
49 Conformational energetics of stable and metastable states formed by DNA triplet repeat oligonucleotides: implications for triplet expansion diseases. Proc Natl Acad Sci U S A 2002 1.01
50 The hydration of globular proteins as derived from volume and compressibility measurements: cross correlating thermodynamic and structural data. J Mol Biol 1996 1.00
51 DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link on the conformational and thermodynamic properties of duplex DNA. J Mol Biol 2000 0.99
52 Volumetric characterizations of the native, molten globule and unfolded states of cytochrome c at acidic pH. J Mol Biol 1995 0.99
53 Differential scanning calorimetry of Cu,Zn-superoxide dismutase, the apoprotein, and its zinc-substituted derivatives. Biochemistry 1988 0.99
54 DNA lesions. A thermodynamic perspective. Ann N Y Acad Sci 1994 0.98
55 Calorimetry of proteins and nucleic acids. Curr Opin Struct Biol 1995 0.97
56 The thermodynamics of DNA structures that contain lesions or guanine tetrads. Curr Opin Struct Biol 1995 0.95
57 Influence of an exocyclic guanine adduct on the thermal stability, conformation, and melting thermodynamics of a DNA duplex. Biochemistry 1992 0.94
58 Berenil [1,3-bis(4'-amidinophenyl)triazene] binding to DNA duplexes and to a RNA duplex: evidence for both intercalative and minor groove binding properties. Biochemistry 1995 0.93
59 High-resolution calorimetric and optical melting profiles of DNA plasmids: resolving contributions from intrinsic melting domains and specifically designed inserts. Biopolymers 1999 0.92
60 Theoretical predictions of DNA hairpin loop conformations: correlations with thermodynamic and spectroscopic data. Biochemistry 1993 0.91
61 A calorimetric investigation of single stranded base stacking in the ribo-oligonucleotide A7. Biophys Chem 1977 0.91
62 The hydration of nucleic acid duplexes as assessed by a combination of volumetric and structural techniques. Biopolymers 1999 0.90
63 Netropsin binding to polyd(AT) X polyd(AT) and to polydA X polydT: a comparative thermodynamic study. Prog Clin Biol Res 1985 0.90
64 Ligand-induced formation of nucleic acid triple helices. Proc Natl Acad Sci U S A 1994 0.90
65 The native and the heat-induced denatured states of alpha-chymotrypsinogen A: thermodynamic and spectroscopic studies. J Mol Biol 1997 0.87
66 Thermodynamic characterization of daunomycin-DNA interactions: microcalorimetric measurements of daunomycin-DNA binding enthalpies. Biochemistry 1991 0.87
67 The impact of an exocyclic cytosine adduct on DNA duplex properties: significant thermodynamic consequences despite modest lesion-induced structural alterations. Biochemistry 1998 0.87
68 Thermodynamic analysis of biomolecules: a volumetric approach. Curr Opin Struct Biol 1998 0.87
69 Volumetric properties of nucleic acids. Biopolymers 1998 0.85
70 The impact of a bistrand abasic lesion on DNA duplex properties. Biopolymers 1996 0.85
71 Calorimetric and spectroscopic investigation of drug--DNA interactions: II. Dipyrandium binding to poly d(AT). Nucleic Acids Res 1983 0.84
72 A Monte Carlo method for generating structures of short single-stranded DNA sequences. Biopolymers 1993 0.84
73 Fluorescence energy transfer monitored competitive equilibria of nucleic acids: applications in thermodynamics and screening. Biopolymers 2002 0.84
74 Base stacking in the dinucleoside phosphate rapa. Biophys Chem 1978 0.83
75 DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles. Biochemistry 1998 0.83
76 Communication between noncontacting macromolecules. Proc Natl Acad Sci U S A 2001 0.83
77 A quantitative method for evaluating the stabilities of nucleic acids. Proc Natl Acad Sci U S A 1999 0.82
78 Vacuum ultraviolet circular dichroism of double stranded nucleic acids. Photochem Photobiol 1986 0.82
79 Relaxation kinetics of the helix-coil transition of a self-complementary ribo-oligonucleotide: A7U7. Biophys Chem 1977 0.82
80 The role of solvents in the stabilization of helical structure: the low pH ribo A8 and A10 double helices in mixed solvents. Biophys Chem 1978 0.82
81 Compressibility as a means to detect and characterize globular protein states. Proc Natl Acad Sci U S A 1996 0.82
82 Preparation and physical properties of conjugates of oligodeoxynucleotides with poly(delta)ornithine peptides. Antisense Res Dev 1993 0.81
83 A terbenzimidazole that preferentially binds and conformationally alters structurally distinct DNA duplex domains: a potential mechanism for topoisomerase I poisoning. Proc Natl Acad Sci U S A 1997 0.80
84 Stabilization of DNA triple-helix formation by appended cationic peptides. Bioconjug Chem 1997 0.80
85 Oligonucleotide-poly-L-ornithine conjugates: binding to complementary DNA and RNA. Antisense Res Dev 1993 0.80
86 Thermodynamic properties of a conformationally constrained intramolecular DNA triple helix. Biochemistry 1997 0.80
87 Counterion association with native and denatured nucleic acids: an experimental approach. J Mol Biol 2001 0.79
88 Minor groove-directed and intercalative ligand-DNA interactions in the poisoning of human DNA topoisomerase I by protoberberine analogs. Biochemistry 1997 0.79
89 Binding studies of a triple-helical peptide model of macrophage scavenger receptor to tetraplex nucleic acids. Biochemistry 1996 0.79
90 Modulation of nucleic acid structure by ligand binding: induction of a DNA.RNA.DNA hybrid triplex by DAPI intercalation. Bioorg Med Chem 1997 0.78
91 Characterizing the DNA binding modes of a topoisomerase I-poisoning terbenzimidazole: evidence for both intercalative and minor groove binding properties. Drug Des Discov 1996 0.77
92 Berenil binding to higher ordered nucleic acid structures: complexation with a DNA and RNA triple helix. Biochemistry 1995 0.77
93 Hybridization properties of oligodeoxynucleotide pairs bridged by polyarginine peptides. Nucleic Acids Res 1996 0.77
94 Tyrosine-PEG-derived poly(ether carbonate)s as new biomaterials. Part II: study of inverse temperature transitions. Biomaterials 1999 0.77
95 Spectroscopic and volumetric investigation of cytochrome c unfolding at alkaline pH: characterization of the base-induced unfolded state at 25 degrees C. FASEB J 1996 0.76
96 Effects of 3,N4-ethenodeoxycytidine on duplex stability and energetics. IARC Sci Publ 1999 0.76
97 Molecular recognition between oligopeptides and nucleic acids. Sequence specific binding of (4S)-(+)- and (4R)-(-)-dihydrokikumycin B to DNA deduced from 1H NMR, footprinting studies and thermodynamic data. J Mol Recognit 1989 0.75
98 Hydration of diglycyl tripeptides with non-polar side chains: a volumetric study. Biophys Chem 1998 0.75