Published in Circ Res on November 01, 1981
Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions. Proc Natl Acad Sci U S A (1987) 5.12
Membrane current through adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells. J Physiol (1985) 1.71
The regulation of ATP-sensitive K+ channel activity in intact and permeabilized rat ventricular myocytes. J Physiol (1990) 1.36
Origin of the potassium and voltage dependence of the cardiac inwardly rectifying K-current (IK1). Biophys J (1992) 1.13
Na,K pump stimulation by intracellular Na in isolated, intact sheep cardiac Purkinje fibers. J Gen Physiol (1988) 1.10
Internal and external K+ help gate the inward rectifier. Biophys J (1989) 1.07
Intracellular sodium-calcium dissociation in early contractile failure in hypoxic ferret papillary muscles. J Physiol (1987) 0.98
Relation of sodium pump inhibition to positive inotropy at low concentrations of ouabain in rat heart muscle. J Physiol (1985) 0.96
The basis for the membrane potential of quiescent cells of the canine coronary sinus. J Physiol (1983) 0.90
The effect of leakage on micro-electrode measurements of intracellular sodium activity in crab muscle fibres. J Physiol (1984) 0.87
Patterns of cellular injury in myocardial ischemia determined by monoclonal antimyosin. Proc Natl Acad Sci U S A (1983) 0.82
Decrease in the transmembrane sodium activity gradient in ferret papillary muscle as a prerequisite to the calcium paradox. J Clin Invest (1988) 0.80
Intracellular potassium activity in guinea pig papillary muscle during prolonged hypoxia. J Clin Invest (1982) 0.78
CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med (2006) 22.76
The cost effectiveness of combination antiretroviral therapy for HIV disease. N Engl J Med (2001) 5.89
Lidocaine block of cardiac sodium channels. J Gen Physiol (1983) 5.13
Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trial. Ann Intern Med (2008) 3.68
Use of genotypic resistance testing to guide hiv therapy: clinical impact and cost-effectiveness. Ann Intern Med (2001) 2.47
Depletion and accumulation of potassium in the extracellular clefts of cardiac Purkinje fibers during voltage clamp hyperpolarization and depolarization. Pflugers Arch (1977) 2.36
The potassium current underlying delayed rectification in cat ventricular muscle. J Physiol (1978) 2.24
Simple sequence repeats in Escherichia coli: abundance, distribution, composition, and polymorphism. Genome Res (2000) 2.24
Calcium conductance and tension in mammalian ventricular muscle. Pflugers Arch (1975) 2.17
Increase in intracellular sodium ion activity during stimulation in mammalian cardiac muscle. Circ Res (1982) 2.14
Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels. J Gen Physiol (2000) 2.09
Tetrodotoxin block of sodium channels in rabbit Purkinje fibers. Interactions between toxin binding and channel gating. J Gen Physiol (1981) 2.07
Functional expression of Drosophila para sodium channels. Modulation by the membrane protein TipE and toxin pharmacology. J Gen Physiol (1997) 1.99
Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition. Gene Ther (2008) 1.94
Voltage-dependent properties of macroscopic and elementary calcium channel currents in guinea pig ventricular myocytes. Pflugers Arch (1986) 1.93
Activation of Drosophila sodium channels promotes modification by deltamethrin. Reductions in affinity caused by knock-down resistance mutations. J Gen Physiol (2000) 1.88
On the mechanism of the negative inotropic effect of acetylcholine. Pflugers Arch (1976) 1.66
Properties and regulation of calcium channels in muscle cells. Rev Physiol Biochem Pharmacol (1990) 1.63
Metabolism and the electrical activity of anoxic ventricular muscle. J Physiol (1973) 1.62
Using gadolinium to identify stretch-activated channels: technical considerations. Am J Physiol (1998) 1.62
A liquid ion-exchanger alternative to KCl for filling intracellular reference microelectrodes. Pflugers Arch (1981) 1.61
Regulation of cellular infiltration into tissue engineering scaffolds composed of submicron diameter fibrils produced by electrospinning. Acta Biomater (2005) 1.60
Secondary cytoreduction for ovarian cancer following cisplatin therapy. J Clin Oncol (1993) 1.57
Heterogeneity of the action potential in isolated rat ventricular myocytes and tissue. Circ Res (1983) 1.56
Membrane currents in cat myocardium: separation of inward and outward components. J Physiol (1978) 1.53
Rilpivirine versus efavirenz in HIV-1-infected subjects receiving emtricitabine/tenofovir DF: pooled 96-week data from ECHO and THRIVE Studies. HIV Clin Trials (2013) 1.53
The second-look operation improves survival in suboptimally debulked stage III ovarian cancer patients. Int J Gynecol Cancer (2005) 1.46
Maximal upstroke velocity as an index of available sodium conductance. Comparison of maximal upstroke velocity and voltage clamp measurements of sodium current in rabbit Purkinje fibers. Circ Res (1984) 1.46
Ion levels and membrane potential in chick heart tissue and cultured cells. J Gen Physiol (1973) 1.43
Stimulation by superantigen. Nature (1991) 1.41
A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent. Circ Res (1985) 1.39
Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. Proc Natl Acad Sci U S A (2000) 1.35
Improved therapy with cisplatin regimens for patients with ovarian carcinoma (FIGO Stages III and IV) as measured by surgical end-staging (second-look operation). Am J Obstet Gynecol (1983) 1.33
Cat ventricular muscle treated with D600: characteristics of calcium channel block and unblock. J Physiol (1984) 1.30
Peripheral nerve involvement in Hunter syndrome (mucopolysaccharidosis II). Arch Neurol (1976) 1.30
Current-voltage relations in ventricular muscle preparations from different species. Pflugers Arch (1978) 1.27
Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials. Advanced Ovarian Cancer Trialists' Group. Br J Cancer (1998) 1.27
Regulation of cellular volume in rabbit ventricular myocytes: bumetanide, chlorothiazide, and ouabain. Am J Physiol (1991) 1.26
Epidemiology of lead poisoning. A comparison between urban and rural children. JAMA (1973) 1.26
Temperature-induced transitory and steady-state changes in the calcium current of guinea pig ventricular myocytes. Pflugers Arch (1985) 1.22
Potential mechanisms of endogenous retroviral-mediated genomic instability in human cancer. Semin Cancer Biol (2010) 1.18
On the mechanism of slow calcium channel block in heart. Pflugers Arch (1980) 1.18
Development of sensitivity to tetrodotoxin in beating chick embryo hearts, single cells, and aggregates. Science (1972) 1.17
Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. Gene Ther (2009) 1.17
Isoproterenol directly stimulates the Na+-K+ pump in isolated cardiac myocytes. Am J Physiol (1986) 1.17
Ventricular action potentials, ventricular extracellular potentials, and the ECG of guinea pig. Circ Res (1985) 1.16
Myelopathy in mucopolysaccharidosis type II (Hunter syndrome). Ann Neurol (1980) 1.16
Retroviral rebound syndrome after cessation of suppressive antiretroviral therapy in three patients with chronic HIV infection. Ann Intern Med (2000) 1.13
The slow inward calcium current in the heart. Annu Rev Physiol (1982) 1.13
Calcium channel block and recovery from block in mammalian ventricular muscle treated with organic channel inhibitors. Pflugers Arch (1982) 1.12
Improved chemotherapy for ovarian cancer with cis-diamminedichloroplatinum and adriamycin. Cancer (1981) 1.10
Potential and K+ activity in skinned muscle fibers. Evidence against a simple Donnan equilibrium. Biophys J (1984) 1.10
Membrane currents and tension in cat ventricular muscle treated with cardiac glycosides. Circ Res (1975) 1.08
On the mechanism underlying the action of D-600 on slow inward current and tension in mammalian myocardium. Circ Res (1977) 1.06
K+, Na+, and Cl- activities in ventricular myocytes isolated from rabbit heart. Am J Physiol (1986) 1.05
An improved liquid ion exchanger for chloride ion-selective microelectrodes. Am J Physiol (1981) 1.05
Endometrial histopathology in 700 patients treated with tamoxifen for breast cancer. Gynecol Oncol (2000) 1.04
Current fluctuations and oscillations in smooth muscle cells from hog carotid artery. Role of the sarcoplasmic reticulum. Circ Res (1989) 1.04
Nimodipine block of calcium channels in rat vascular smooth muscle cell lines. Exceptionally high-affinity binding in A7r5 and A10 cells. J Gen Physiol (1989) 1.04
Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-peptide tetramers to TCR. J Immunol (2001) 1.03
Isolation of single atrial and ventricular cells from the human heart. Can Med Assoc J (1982) 1.02
Prevention of myocardial intracellular edema induced by St. Thomas' Hospital cardioplegic solution. J Mol Cell Cardiol (1991) 1.02
Whole-cell calcium current in guinea-pig ventricular myocytes dialysed with guanine nucleotides. J Physiol (1990) 1.01
Elevation of serum CA 125 prior to diagnosis of an epithelial ovarian carcinoma. Gynecol Oncol (1985) 1.01
A comparison of the antiemetic effects of droperidol and prochlorperazine in chemotheray with cis-platinum. Gynecol Oncol (1980) 1.01
Maintenance of resting potential in anoxic guinea pig ventricular muscle: electrogenic sodium pumping. Science (1971) 1.00
Primary prophylaxis for Pneumocystis carinii pneumonia in HIV-infected people with CD4 counts below 200/mm3: a cost-effectiveness analysis. J Acquir Immune Defic Syndr (1991) 1.00
Intracellular chloride activity in mammalian ventricular muscle. Am J Physiol (1981) 1.00
Nodulisporic acid opens insect glutamate-gated chloride channels: identification of a new high affinity modulator. Biochemistry (2000) 0.99
Single cells from adult mammalian heart: isolation procedure and preliminary electrophysiological studies. Can J Physiol Pharmacol (1981) 0.99
Depletion and accumulation of potassium in the extracellular clefts of cardiac Purkinje fibers during voltage clamp hyperpolarization and depolarization: experiments in sodium-free bathing media. J Gen Physiol (1977) 0.98
Action potentials, ionic currents and cell water in guinea pig ventricular preparations exposed to dimethyl sulfoxide. J Pharmacol Exp Ther (1995) 0.97
Placental and fetal involvement by maternal malignancy: a report of rectal carcinoma and review of the literature. Am J Obstet Gynecol (1973) 0.97
Anoxia-recovery cycle in ventricular muscle: action potential duration, contractility and ATP content. Pflugers Arch (1971) 0.97
The effect of 2,4-dinitrophenol on electrical and mechanical activity, metabolism and ion movements in guinea-pig ventricular muscle. Br J Pharmacol (1972) 0.96
Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland. Recent Prog Horm Res (1996) 0.96
Modulation of cardiac Na(+) current by gadolinium, a blocker of stretch-induced arrhythmias. Am J Physiol Heart Circ Physiol (2001) 0.95
Tetrodotoxin sensitivity of cultured embryonic heart cells depends on cell interactions. J Cell Biol (1973) 0.95
Electrical activity in embryonic heart cell aggregates. Developmental aspects. Pflugers Arch (1975) 0.95
Kinetic evidence distinguishing volume-sensitive chloride current from other types in guinea-pig ventricular myocytes. J Physiol (1996) 0.94
The inhibition of receptor-mediated and voltage-dependent calcium entry by the antiproliferative L-651,582. J Biol Chem (1991) 0.94
Modulation of rabbit ventricular cell volume and Na+/K+/2Cl- cotransport by cGMP and atrial natriuretic factor. J Gen Physiol (1992) 0.94
DNP-induced dissipation of ATP in anoxic ventricular muscle. J Physiol (1973) 0.93
Dictyostelium discoideum mutants with temperature-sensitive defects in endocytosis. J Cell Biol (1994) 0.93
External potassium and baby hamster kidney cells: intracellular ions, ATP, growth, DNA synthesis and membrane potential. Dev Biol (1972) 0.93
L-type Ca2+ current in guinea pig ventricular myocytes treated with modulators of tyrosine phosphorylation. Am J Physiol (1999) 0.93
Membrane conductance measurements in cat ventricular muscle. J Mol Cell Cardiol (1978) 0.93
Membrane-delimited stimulation of heart cell calcium current by beta-adrenergic signal-transducing Gs protein. Am J Physiol (1990) 0.92
Multiple effects of ouabain on BHK cells. Exp Cell Res (1972) 0.91
Swelling-activated chloride current is persistently activated in ventricular myocytes from dogs with tachycardia-induced congestive heart failure. Circ Res (1999) 0.91
Intra- and extracellular potassium activities, acetylcholine and resting potential in guinea pig atria. Circ Res (1984) 0.91
Activation of cardiac chloride conductance by the tyrosine kinase inhibitor, genistein. Br J Pharmacol (1996) 0.91
Voltage-gated calcium currents have two opposing effects on the secretion of aldosterone. Am J Physiol (1995) 0.91
WIN 17317-3, a new high-affinity probe for voltage-gated sodium channels. Biochemistry (1999) 0.90
Existence of a transient outward K(+) current in guinea pig cardiac myocytes. Am J Physiol Heart Circ Physiol (2000) 0.90
Treatment of advanced ovarian cancer with cis=dichlorodiammineplatinum(II): poor-risk patients with intensive prior therapy. Cancer Treat Rep (1978) 0.90
Adenosinetriphosphate partition in cardiac muscle with respect to transmembrane electrical activity. Pflugers Arch (1971) 0.90
cGMP and atrial natriuretic factor regulate cell volume of rabbit atrial myocytes. Circ Res (1995) 0.90
Sodium currents in segments of human heart cells. Science (1983) 0.90