Published in Nature on March 06, 1980
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts. Proc Natl Acad Sci U S A (1981) 1.62
Regulation of human fibroblast growth rate by both noncycling cell fraction transition probability is shown by growth in 5-bromodeoxyuridine followed by Hoechst 33258 flow cytometry. Proc Natl Acad Sci U S A (1983) 1.11
Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance. Mol Cell Biol (1981) 1.10
Analyses of bromodeoxyuridine-associated sister chromatid exchanges (SCEs) in Bloom syndrome based on cell fusion: single and twin SCEs in endoreduplication. Proc Natl Acad Sci U S A (1983) 0.97
Thymidine-induced mutations in mammalian cells: sequence specificity and implications for mutagenesis in vivo. Proc Natl Acad Sci U S A (1992) 0.91
Aphidicolin-resistant mutants of mouse lymphoma L5178Y cells with a high incidence of spontaneous sister chromatid exchanges. Genetics (1986) 0.79
Sensitivity of lymphocytes from patients with systemic lupus erythematosus to the induction of sister chromatid exchanges by alkylating agents and bromodeoxyuridine. Ann Rheum Dis (1987) 0.77
Fra(10)(q25): the BrdU effect is substitution-dependent. Am J Hum Genet (1985) 0.75
Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion. Proc Natl Acad Sci U S A (1985) 5.50
Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization. Science (1985) 5.23
Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol. Somatic Cell Genet (1976) 5.05
Regional localization on the human X of DNA segments cloned from flow sorted chromosomes. Nucleic Acids Res (1982) 4.67
Automatic measurement of sister chromatid exchange frequency. J Histochem Cytochem (1977) 4.24
Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy. Nature (1986) 4.13
Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell (1983) 4.13
Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes. Proc Natl Acad Sci U S A (1973) 3.76
Isolation of molecular probes associated with the chromosome 15 instability in the Prader-Willi syndrome. Proc Natl Acad Sci U S A (1986) 3.54
The effect of hexose on chloramphenicol sensitivity and resistance in Chinese hamster cells. J Cell Physiol (1979) 3.33
Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion. Am J Med Genet (1989) 3.22
Isolation of human chromosome 13-specific DNA sequences cloned from flow sorted chromosomes and potentially linked to the retinoblastoma locus. Cancer Genet Cytogenet (1984) 3.17
Spectral studies on 33258 Hoechst and related bisbenzimidazole dyes useful for fluorescent detection of deoxyribonucleic acid synthesis. J Histochem Cytochem (1976) 2.84
Localization of sister chromatid exchanges in human chromosomes. Science (1974) 2.50
Polyethylene glycol-induced mammalian cell hybridization: effect of polyethylene glycol molecular weight and concentration. Somatic Cell Genet (1976) 2.46
Regulation of pigment synthesis in mammalian cells, as studied by somatic hybridization. Proc Natl Acad Sci U S A (1966) 2.36
Total substitution of bromodeoxyuridine for thymidine in the DNA of a bromodeoxyuridine-dependent cell line. Proc Natl Acad Sci U S A (1974) 2.24
Isolation of fetal DNA from nucleated erythrocytes in maternal blood. Proc Natl Acad Sci U S A (1990) 2.15
Restriction fragment length polymorphisms within proximal 15q and their use in molecular cytogenetics and the Prader-Willi syndrome. Am J Med Genet (1989) 2.00
Coamplification and coexpression of human tissue-type plasminogen activator and murine dihydrofolate reductase sequences in Chinese hamster ovary cells. Mol Cell Biol (1985) 1.97
Analysis of deoxyribonucleic acid replication in human X chromosomes by fluorescence microscopy. Am J Hum Genet (1976) 1.90
Herpes simplex virus as a source of thymidine kinase for thymidine kinase-deficient mouse cells: suppression and reactivation of the viral enzyme. Proc Natl Acad Sci U S A (1973) 1.87
Accurate and superaccurate gene mapping. Am J Hum Genet (1985) 1.85
Elimination of mitochondrial elements and improved viability in hybrid cells. Somatic Cell Genet (1981) 1.78
High spontaneous mutation frequency in shuttle vector sequences recovered from mammalian cellular DNA. Mol Cell Biol (1984) 1.73
BrdU-33258 Hoechst analysis of DNA replication in human lymphocytes with supernumerary or structurally abnormal X chromosomes. Chromosoma (1976) 1.66
Clinical heterogeneity associated with deletions in the long arm of chromosome 15: report of 3 new cases and their possible genetic significance. Am J Med Genet (1987) 1.62
Stimulated human phagocytes produce cytogenetic changes in cultured mammalian cells. N Engl J Med (1983) 1.62
Sister chromatid exchanges, indices of human chromosome damage and repair: detection by fluorescence and induction by mitomycin C. Proc Natl Acad Sci U S A (1974) 1.59
The interrelationships and stability of Coulter S-determined blood indices. J Clin Pathol (1973) 1.57
5-Azacytidine-induced reactivation of a herpes simplex thymidine kinase gene. Science (1982) 1.56
Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia. Proc Natl Acad Sci U S A (1975) 1.55
Localization of DNA sequences in region Xp21 of the human X chromosome: search for molecular markers close to the Duchenne muscular dystrophy locus. Am J Hum Genet (1985) 1.52
Microfluorometric analysis of deoxyribonucleic acid replication kinetics and sister chromatid exchanges in human chromosomes. J Histochem Cytochem (1974) 1.49
Molecular detection and differentiation of deletions in band 13q14 in human retinoblastoma. Cancer Genet Cytogenet (1986) 1.47
Identification and isolation of transcribed human X chromosome DNA sequences. Nucleic Acids Res (1983) 1.45
Bromodeoxyuridine dependence--a new mutation in mammalian cells. Proc Natl Acad Sci U S A (1973) 1.41
Physical mapping of drug resistance mutations defines an active center of the herpes simplex virus DNA polymerase enzyme. J Virol (1981) 1.40
Gene expression in somatic cell hybrids. Annu Rev Genet (1974) 1.37
The amyloid beta protein gene is not duplicated in brains from patients with Alzheimer's disease. Science (1987) 1.35
Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences. Mol Cell Biol (1983) 1.35
Regulation of specific functions of glial cells in somatic hybrids. II. Control of inducibility of glycerol-3-phosphate dehydrogenase. Proc Natl Acad Sci U S A (1970) 1.34
Thermolysin: a zinc metalloenzyme. Biochem Biophys Res Commun (1969) 1.32
Sister chromatid exchange formation. Annu Rev Genet (1981) 1.32
Cloning and analysis of reverse transcript P160 genomes of Abelson murine leukemia virus. J Virol (1983) 1.30
Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA. Proc Natl Acad Sci U S A (1978) 1.28
Cell fusion and intramembrane particle distribution in polyethylene glycol-resistant cells. J Cell Biol (1983) 1.27
Optical studies of the interaction of 33258 Hoechst with DNA, chromatin, and metaphase chromosomes. Chromosoma (1975) 1.27
Moderately repeated DNA sequences specific for the short arm of the human Y chromosome are present in XX males and reduced in copy number in an XY female. Nucleic Acids Res (1986) 1.26
Sequence analysis of spontaneous mutations in a shuttle vector gene integrated into mammalian chromosomal DNA. Proc Natl Acad Sci U S A (1987) 1.26
Isolation of mouse x-chromosome specific DNA from an x-enriched lambda phage library derived from flow sorted chromosomes. Cytometry (1982) 1.24
Differential amplification, assembly, and relocation of multiple DNA sequences in human neuroblastomas and neuroblastoma cell lines. Proc Natl Acad Sci U S A (1985) 1.23
Induction of mammalian somatic cell hybridization by polyethylene glycol. Methods Cell Biol (1977) 1.23
Analysis of sister chromatid exchange formation in vivo in mouse spermatogonia as a new test system for environmental mutagens. Nature (1976) 1.23
Late replication in an X-autosome translocation in the mouse: correlation with genetic inactivation and evidence for selective effects during embryogenesis. Proc Natl Acad Sci U S A (1979) 1.21
The 35 kd pulmonary surfactant-associated protein is encoded on chromosome 10. Hum Genet (1987) 1.21
Surveyor substrates: energy-transfer gauges of active center topography during catalysis. Proc Natl Acad Sci U S A (1970) 1.20
Construction of a chromosome 16-enriched phage library and characterization of several DNA segments from 16p. Hum Genet (1987) 1.18
Fluorescence analysis of late DNA replication in human metaphase chromosomes. Somatic Cell Genet (1975) 1.18
Membrane alterations and other morphological features associated with polyethylene glycol-induced cell fusion. J Cell Sci (1979) 1.15
Flow cytometric characterization of the response of Fanconi's anemia cells to mitomycin C treatment. Cytometry (1982) 1.15
Spectral properties of cobalt carboxypeptidase. The effects of substrates and inhibitors. Biochemistry (1971) 1.15
Protein-nucleic acid interactions. II. Oligopeptide-polyribonucleotide binding studies. Biochemistry (1967) 1.14
5-Bromodeoxyuridine-dependent increase in sister chromatid exchange formation in Bloom's syndrome is associated with reduction in topoisomerase II activity. Exp Cell Res (1987) 1.14
Regulation of malanin synthesis in mammalian cells: effect of gene dosage on the expression of differentiation. Proc Natl Acad Sci U S A (1972) 1.13
High resolution analysis of the timing of replication of specific DNA sequences during S phase of mammalian cells. Nucleic Acids Res (1983) 1.11
Flow cytometric analysis of bromodeoxyuridine-substituted cells stained with 33258 Hoechst. J Histochem Cytochem (1977) 1.11
Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance. Mol Cell Biol (1981) 1.10
High spontaneous mutation frequency of BPV shuttle vector. Somat Cell Mol Genet (1985) 1.10
Characterising and correcting batch variation in an automated direct infusion mass spectrometry (DIMS) metabolomics workflow. Anal Bioanal Chem (2013) 1.08
Isolation of DNA sequences on human chromosome 21 by application of a recombination-based assay to DNA from flow-sorted chromosomes. Hum Genet (1988) 1.08
A simplified technique for in vivo analysis of sister-chromatid exchanges using 5-bromodeoxyuridine tablets. Cytogenet Cell Genet (1977) 1.08
Fluorescence analysis of late DNA replication in mouse metaphase chromosomes using BUdR and 33258 Hoechst. Exp Cell Res (1976) 1.07
Protein-nucleic acid interactions. 3. Cation effect on binding strength and specificity. Biochemistry (1967) 1.06
Efficient recovery and sequencing of mutant genes from mammalian chromosomal DNA. Proc Natl Acad Sci U S A (1986) 1.06
Y-190, a DNA probe for the sensitive detection of Y-derived marker chromosomes and mosaicism. Hum Genet (1987) 1.06
Patterns of late replication in X chromosomes of human lymphoid cells. Cancer Genet Cytogenet (1981) 1.05
Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by thymidine and suppressed by deoxycytidine. Nature (1978) 1.04
Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by purine deoxyribonucleosides. Somatic Cell Genet (1979) 1.03
Distance measurements at the active site of carboxypeptidase A during catalysis. Biochemistry (1972) 1.03
Sister chromatid exchange analysis. Am J Hum Genet (1980) 1.02
Regulation of gene expression in somatic cell hybrids: a review. In Vitro (1974) 1.01
Detection of DNA synthesis in interphase nuclei by fluorescence microscopy. J Cell Biol (1974) 1.01
Flow sorting of the mouse Cattanach X chromosome, T (X; 7) 1 Ct, in an active or inactive state. Cytogenet Cell Genet (1981) 0.99
Microfluorometric detection of asymmetry in the centromeric region of mouse chromosomes. Exp Cell Res (1974) 0.99
Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. J Histochem Cytochem (1975) 0.98
Centric fusion, satellite DNA, and DNA polarity in mouse chromosomes. Science (1974) 0.98
Malignancy of somatic cell hybrids. Nature (1969) 0.98
Construction of a human X-chromosome-enriched phage library which facilitates analysis of specific loci. Gene (1985) 0.97
DNA base sequence changes induced by ethyl methanesulfonate in a chromosomally integrated shuttle vector gene in mouse cells. Somat Cell Mol Genet (1987) 0.97
Sister-chromatid exchanges: a report of the GENE-TOX program. Mutat Res (1981) 0.97
Anaerobic metabolism at thermal extremes: a metabolomic test of the oxygen limitation hypothesis in an aquatic insect. Integr Comp Biol (2013) 0.96
Deoxycytidine reverses the suppression of pigmentation caused by 5-BrdUrd without changing the amount of 5-BrdUrd in DNA. Cell (1977) 0.96
Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia. Mutat Res (1989) 0.96