Published in Cell on August 01, 1980
Histone mRNA concentrations are regulated at the level of transcription and mRNA degradation. Proc Natl Acad Sci U S A (1983) 4.46
Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system. Mol Cell Biol (1988) 3.96
Coordinate regulation of multiple histone mRNAs during the cell cycle in HeLa cells. Nucleic Acids Res (1983) 3.35
Regulation of histone mRNA production and stability in serum-stimulated mouse 3T6 fibroblasts. Mol Cell Biol (1983) 3.13
Cell cycle regulation of mouse H3 histone mRNA metabolism. Mol Cell Biol (1984) 2.97
Rapid reversible changes in the rate of histone gene transcription and histone mRNA levels in mouse myeloma cells. Mol Cell Biol (1984) 2.48
Analysis of histone gene expression during the cell cycle in HeLa cells by using cloned human histone genes. Proc Natl Acad Sci U S A (1982) 2.28
Inhibition of protein synthesis stabilizes histone mRNA. Mol Cell Biol (1984) 2.14
Distinct transcription factors bind specifically to two regions of the human histone H4 promoter. Proc Natl Acad Sci U S A (1986) 1.71
Cell cycle stage-specific accumulation of mRNAs encoding tubulin and other polypeptides in Chlamydomonas. Proc Natl Acad Sci U S A (1982) 1.43
Autogenous regulation of histone mRNA decay by histone proteins in a cell-free system. Mol Cell Biol (1987) 1.21
Influence of DNA synthesis inhibition on the coordinate expression of core human histone genes during S phase. Nucleic Acids Res (1983) 1.21
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Isolation of a clone containing human histone genes. Nucleic Acids Res (1981) 1.08
Structure and organization of the chicken H2B histone gene family. Nucleic Acids Res (1987) 1.08
Effect of adenovirus infection on expression of human histone genes. Mol Cell Biol (1984) 0.95
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Biosynthesis and posttranslational acetylation of histones during spherulation of Physarum polycephalum. Nucleic Acids Res (1986) 0.85
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Asynchronous appearance of newly synthesized histone H1 subfractions in HeLa chromatin. J Cell Biol (1981) 0.77
Rate of somatic mutation in immunoglobulin production by mouse myeloma cells. Proc Natl Acad Sci U S A (1971) 3.83
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels. Nature (1997) 2.86
Molecular cloning and expression of the mouse ornithine decarboxylase gene. Proc Natl Acad Sci U S A (1984) 2.83
Cloning of mouse myeloma cells and detection of rare variants. J Cell Physiol (1972) 2.63
Mutations causing charge alterations in regulatory subunits of the cAMP-dependent protein kinase of cultured S49 lymphoma cells. Cell (1977) 2.20
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Inhibition of protein synthesis stabilizes histone mRNA. Mol Cell Biol (1984) 2.14
Prevention of rapid intracellular degradation of ODC by a carboxyl-terminal truncation. Science (1989) 2.07
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Mutations in immunoglobulin-producing mouse myeloma cells. Science (1973) 1.94
Immunoglobulin production: method for quantitatively detecting variant myeloma cells. Science (1970) 1.81
Selection of a variant lymphoma cell deficient in adenylate cyclase. Science (1975) 1.76
Degradation of ornithine decarboxylase: exposure of the C-terminal target by a polyamine-inducible inhibitory protein. Mol Cell Biol (1993) 1.75
Cloning and sequencing of the ornithine decarboxylase gene from Trypanosoma brucei. Implications for enzyme turnover and selective difluoromethylornithine inhibition. J Biol Chem (1987) 1.61
Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme. Mol Cell Biol (1992) 1.57
Cyclic AMP-dependent protein kinase: pivotal role in regulation of enzyme induction and growth. Science (1975) 1.51
Suppression of immunoglobulin synthesis by cellular hybridization. Nat New Biol (1971) 1.50
Mouse ornithine decarboxylase gene: cloning, structure, and expression. Proc Natl Acad Sci U S A (1988) 1.46
Ubiquitin-free routes into the proteasome. Cell Mol Life Sci (2004) 1.45
Somatic genetic analysis of cyclic AMP action: selection of unresponsive mutants. J Cell Physiol (1975) 1.44
Two-dimensional gel analysis of cyclic AMP effects in cultured S49 mouse lymphoma cells: protein modifications, inductions and repressions. Cell (1979) 1.44
Trypanosome ornithine decarboxylase is stable because it lacks sequences found in the carboxyl terminus of the mouse enzyme which target the latter for intracellular degradation. J Biol Chem (1990) 1.43
Mouse ornithine decarboxylase. Complete amino acid sequence deduced from cDNA. J Biol Chem (1985) 1.42
High-risk human papillomavirus E6 protein has two distinct binding sites within p53, of which only one determines degradation. J Virol (1996) 1.42
Agonist-specific refractoriness induced by isoproterenol. Studies with mutant cells. J Biol Chem (1976) 1.39
A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells. Proc Natl Acad Sci U S A (1975) 1.36
The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats. J Pharmacol Exp Ther (2004) 1.35
Multiple mechanisms are responsible for altered expression of ornithine decarboxylase in overproducing variant cells. Mol Cell Biol (1986) 1.34
A mouse lymphoma cell mutant whose major protein product is ornithine decarboxylase. J Biol Chem (1983) 1.33
Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases. Structure (1999) 1.31
Polyamine-mediated regulation of mouse ornithine decarboxylase is posttranslational. Mol Cell Biol (1989) 1.30
Structural elements of ornithine decarboxylase required for intracellular degradation and polyamine-dependent regulation. Mol Cell Biol (1992) 1.30
Ornithine decarboxylase in difluoromethylornithine-resistant mouse lymphoma cells. Two-dimensional gel analysis of synthesis and turnover. J Biol Chem (1983) 1.28
Kinase-negative mutants of S49 mouse lymphoma cells carry a trans-dominant mutation affecting expression of cAMP-dependent protein kinase. Cell (1978) 1.27
Increased histone mRNA levels during inhibition of protein synthesis. Biochem Biophys Res Commun (1983) 1.22
Nerve growth factor rapidly induces ornithine decarboxylase mRNA in PC12 rat pheochromocytoma cells. Proc Natl Acad Sci U S A (1985) 1.20
Cyclic AMP, a nonessential regulator of the cell cycle. Proc Natl Acad Sci U S A (1975) 1.18
Resolution of basic cellular proteins including histone variants by two-dimensional gel electrophoresis: evaluation of lysine to arginine ratios and phosphorylation. Anal Biochem (1980) 1.17
Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMP. Proc Natl Acad Sci U S A (1977) 1.12
Altered adenosine cyclic 3',5'-monophosphate synthesis and degradation by C-6 astrocytoma cells following prolonged exposure to norepinephrine. Mol Pharmacol (1976) 1.12
Antizyme2 is a negative regulator of ornithine decarboxylase and polyamine transport. J Biol Chem (1999) 1.11
Regulation of mouse ornithine decarboxylase activity by cell growth, serum and tetradecanoyl phorbol acetate is governed primarily by sequences within the coding region of the gene. Nucleic Acids Res (1989) 1.09
Degradation of ornithine decarboxylase by the mammalian and yeast 26S proteasome complexes requires all the components of the protease. Eur J Biochem (1995) 1.09
Genetic analysis of cyclic AMP in a mammalian cell. Adv Cyclic Nucleotide Res (1975) 1.09
Somatic genetic analysis of cyclic AMP action: characterization of unresponsive mutants. J Cell Physiol (1975) 1.07
Cyclic AMP-induced cytolysis in S49 cells: selection of an unresponsive "deathless" mutant. Cell (1977) 1.06
Distinct domains of antizyme required for binding and proteolysis of ornithine decarboxylase. Mol Cell Biol (1994) 1.04
Trypanosoma brucei ornithine decarboxylase: enzyme purification, characterization, and expression in Escherichia coli. J Biol Chem (1988) 1.03
The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics? Psychopharmacology (Berl) (2001) 1.02
Dominant negative mutants of ornithine decarboxylase. J Biol Chem (1992) 1.01
Complementation of a polyamine-deficient Escherichia coli mutant by expression of mouse ornithine decarboxylase. Mol Cell Biol (1987) 1.01
Regulated degradation of yeast ornithine decarboxylase. J Biol Chem (1999) 0.99
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Localization of TIMP in cycling mouse hair. Development (1991) 0.97
Expression and post-transcriptional regulation of ornithine decarboxylase during early Xenopus development. Eur J Biochem (1991) 0.96
Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells. J Cell Biol (1983) 0.96
Molecular mechanisms of cyclic AMP action: a genetic approach. Recent Prog Horm Res (1976) 0.95
Identification of a region of p53 that confers lability. J Biol Chem (1996) 0.93
The N terminus of antizyme promotes degradation of heterologous proteins. J Biol Chem (1996) 0.90
Cholera toxin can catalyze ADP-ribosylation of cytoskeletal proteins. J Cell Biol (1981) 0.88
Complementation analysis of hormone-sensitive adenylate cyclase. Nature (1978) 0.88
Identification by direct photoaffinity labeling of an altered phosphodiesterase in a mutant S49 lymphoma cell. J Biol Chem (1983) 0.88
Cultured S49 mouse T lymphoma cells. Methods Enzymol (1987) 0.88
Mechanism of lymphoma cell death induced by cyclic AMP. Am J Pathol (1975) 0.87
Norepinephrine-dependent protein phosphorylation in intact C-6 glioma cells. Analysis by two-dimensional gel electrophoresis. Mol Pharmacol (1980) 0.87
Studies of cyclic AMP action using mutant tissue culture cells. In Vitro (1978) 0.86
alpha5 subunit in Trypanosoma brucei proteasome can self-assemble to form a cylinder of four stacked heptamer rings. Biochem J (1999) 0.86
Platelet-derived growth factor does not induce c-fos in NIH 3T3 cells expressing the EJ-ras oncogene. Mol Cell Biol (1988) 0.85
The ornithine decarboxylase gene of Caenorhabditis elegans: cloning, mapping and mutagenesis. Genetics (1995) 0.85
Regulation of phosphodiesterase and ornithine decarboxylase by cAMP is cell cycle independent. J Cell Physiol (1979) 0.85
Revertants of an S49 cell mutant that expresses altered cyclic AMP-dependent protein kinase. Mol Cell Biol (1982) 0.85
Revertants of a trans-dominant S49 mouse lymphoma mutant that affects expression of cAMP-dependent protein kinase. Cell (1983) 0.85
Isolation and characterization of S49 lymphoma cells deficient in beta-adrenergic receptors: relation of receptor number to activation of adenylate cyclase. Mol Pharmacol (1979) 0.85
Quantitative forward-mutation specificity of mono-functional alkylating agents, ICR-191, and aflatoxin B1 in mouse lymphoma cells. Mutat Res (1982) 0.85
Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs. Mol Pharmacol (1992) 0.84
Developmental effect of polyamine depletion in Caenorhabditis elegans. Biochem J (1998) 0.84
An Mr = 52,000 peptide can mediate effects on cholera toxin on adenylate cyclase in intact cells. Mol Pharmacol (1981) 0.84
Variations in the synthesis and assembly of immunoglobulins by mouse myeloma cells: a genetic and biochemical analysis. J Cell Physiol (1970) 0.83
A homolog of mammalian antizyme is present in fission yeast Schizosaccharomyces pombe but not detected in budding yeast Saccharomyces cerevisiae. Bioinformatics (2000) 0.83
Cell cycle specific inhibitors. Pharmacol Ther (1989) 0.82
Regulation of S49 lymphoma cell growth by cyclic adenosine 3':5'-monophosphate. Cancer Res (1978) 0.82
Coexpression of mutant and wild type protein kinase in lymphoma cells resistant to dibutyryl cyclic AMP. J Cell Physiol (1977) 0.82
Synthesis and biological activity of spirocyclic benzopyran imidazolone potassium channel openers. J Med Chem (1993) 0.81
Multiple active conformers of mouse ornithine decarboxylase. Biochem J (1993) 0.81
Mechanism of 2-aminopurine mutagenesis in mouse T-lymphosarcoma cells. Mol Cell Biol (1982) 0.79
Rat antizyme inhibits the activity but does not promote the degradation of mouse ornithine decarboxylase in Trypanosoma brucei. J Biol Chem (1995) 0.79
Linkage genetics of mouse ornithine decarboxylase (Odc). Genomics (1989) 0.79
Reversion of an S49 cell cyclic AMP-dependent protein kinase structural gene mutant occurs primarily by functional elimination of mutant gene expression. Mol Cell Biol (1983) 0.78
Subunit interaction in cyclic AMP-dependent protein kinase of mutant lymphoma cells. Proc Natl Acad Sci U S A (1977) 0.77
Growth regulation of S49 lymphoma cells: analysis of cAMP responsiveness and polyamine metabolism. Adv Cyclic Nucleotide Res (1981) 0.77
A functional mouse ornithine decarboxylase gene (Odc) maps to chromosome 12: further evidence of homoeology between mouse chromosome 12 and the short arm of human chromosome 2. Cytogenet Cell Genet (1988) 0.77
Papaverine, a potent inhibitor of respiration in C-6 astrocytoma cells. Mol Pharmacol (1974) 0.77
Independent mechanisms of cyclic AMP and glucocorticoid action. Nature (1977) 0.76
Separation and purification of S49 mouse lymphoma histones by reversed-phase high-performance liquid chromatography. Anal Biochem (1987) 0.76
Crystallization of a mammalian ornithine decarboxylase. Proteins (1996) 0.76
The regulation of immunoglobulin synthesis and assembly. Ann N Y Acad Sci (1971) 0.76
P388 leukaemia cells resistant to the anthracycline menogaril lack multidrug resistant phenotype. Br J Cancer (1990) 0.75