Published in Biochemistry on October 14, 1980
DNA structure and perturbation by drug binding. Biochem J (1987) 1.41
DNA fragment conformations IV - Helix-coil transition and conformation of d-CCATGG in aqueous solution by 1H-NMR spectroscopy. Nucleic Acids Res (1982) 1.01
Hydrogen bonding, overlap geometry, and sequence specificity in anthracycline antitumor antibiotic.DNA complexes in solution. Proc Natl Acad Sci U S A (1981) 0.95
Prediction of 1H NMR chemical shifts of DNA oligomers. Nucleic Acids Res (1983) 0.78
1H-NMR study of the interaction of daunomycin with B-DNA helices of methylated oligodeoxynucleotides. Nucleic Acids Res (1984) 0.78
Exposed protein on the intact human erythrocyte. Biochemistry (1971) 4.56
Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to "integrin". J Biol Chem (1987) 3.87
The arrangement of proteins in the human erythrocyte membrane. Biochem Biophys Res Commun (1970) 3.54
Pregnant teenagers' knowledge and use of emergency contraception. BMJ (1995) 3.51
Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis. J Biol Chem (1977) 3.19
Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function. Nature (1999) 2.71
Identification of membrane proteins mediating the interaction of human platelets. J Cell Biol (1980) 2.65
The formation of cis-3-nonenal, trans-2-nonenal and hexanal from linoleic acid hydroperoxide isomers by a hydroperoxide cleavage enzyme system in cucumber (Cucumis sativus) fruits. Biochim Biophys Acta (1976) 2.48
Platelet membrane defects in Glanzmann's thrombasthenia. Evidence for decreased amounts of two major glycoproteins. J Clin Invest (1977) 2.43
Effect of trypsin on the exposed polypeptides and glycoproteins in the human platelet membrane. Biochemistry (1972) 2.41
Effects of adrenaline on human blood platelets. J Physiol (1967) 2.38
Platelet glycoproteins IIb and IIIa: evidence for a family of immunologically and structurally related glycoproteins in mammalian cells. Proc Natl Acad Sci U S A (1986) 2.30
Role of an inhibitory pyrimidine element and polypyrimidine tract binding protein in repression of a regulated alpha-tropomyosin exon. RNA (1998) 2.18
Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex. J Biol Chem (1982) 2.10
Ca2+-mediated association of glycoprotein G (thrombinsensitive protein, thrombospondin) with human platelets. J Biol Chem (1980) 2.08
Biochemical studies of two patients with the gray platelet syndrome. Selective deficiency of platelet alpha granules. J Clin Invest (1980) 2.01
Human and bovine endothelial cells synthesize membrane proteins similar to human platelet glycoproteins IIb and IIIa. J Biol Chem (1985) 2.00
Ca2+-dependent protease in human platelets. Specific cleavage of platelet polypeptides in the presence of added Ca2+. J Biol Chem (1977) 1.99
Comparison of cDNA-derived protein sequences of the human fibronectin and vitronectin receptor alpha-subunits and platelet glycoprotein IIb. Biochemistry (1987) 1.99
The release of nucleotides, 5-hydroxytryptamine and enzymes from human blood platelets during aggregation. J Physiol (1968) 1.97
Inhibition of actin polymerization in blood platelets by cytochalasins. Nature (1981) 1.92
Smooth muscle-specific switching of alpha-tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon. EMBO J (1994) 1.91
Nuclear magnetic resonance spectroscopy of amino acids, peptides, and proteins. Adv Protein Chem (1970) 1.89
Molecular defects in interactions of platelets with the vessel wall. N Engl J Med (1984) 1.78
Calcium-dependent proteolysis occurs during platelet aggregation. J Biol Chem (1983) 1.74
Outside-in integrin signal transduction. Alpha IIb beta 3-(GP IIb IIIa) tyrosine phosphorylation induced by platelet aggregation. J Biol Chem (1996) 1.70
Platelet membrane glycoproteins implicated in ristocetin-induced aggregation. Studies of the proteins on platelets from patients with Bernard-Soulier syndrome and von Willebrand's disease. J Clin Invest (1976) 1.67
Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix. J Biol Chem (1987) 1.65
Identification of two proteins (actin-binding protein and P235) that are hydrolyzed by endogenous Ca2+-dependent protease during platelet aggregation. J Biol Chem (1985) 1.59
Changes in the cytoskeletal structure of human platelets following thrombin activation. J Biol Chem (1981) 1.58
Calcium regulation of the platelet membrane glycoprotein IIb-IIIa complex. J Biol Chem (1985) 1.56
Thrombin-induced platelet aggregation is mediated by a platelet plasma membrane-bound lectin. Science (1978) 1.55
Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa. J Biol Chem (1993) 1.53
Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms. J Biol Chem (1993) 1.53
Atopic eczema and the home environment. Br J Dermatol (2001) 1.52
The mechanism of action of ribonuclease. Proc Natl Acad Sci U S A (1969) 1.51
Lipoxygenase from potato tubers. Partial purification and properties of an enzyme that specifically oxygenates the 9-position of linoleic acid. Biochem J (1971) 1.49
The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering. J Cell Biol (1987) 1.47
Structure of human platelet membrane glycoproteins IIb and IIIa as determined by electron microscopy. J Biol Chem (1985) 1.47
Binding of flexible ligands to macromolecules. Nature (1975) 1.45
Role of phosphorylation in mediating the association of myosin with the cytoskeletal structures of human platelets. J Biol Chem (1982) 1.44
Spectrin is associated with membrane-bound actin filaments in platelets and is hydrolyzed by the Ca2+-dependent protease during platelet activation. Blood (1987) 1.43
Platelet membrane glycoproteins: functions in cellular interactions. Annu Rev Cell Biol (1990) 1.42
Correction for light absorption in fluorescence studies of protein-ligand interactions. Anal Biochem (1983) 1.40
Influence of globin structure on the state of the heme. II. Allosteric transitions in methemoglobin. Biochemistry (1974) 1.40
Influences on the ethical beliefs of graduate students concerning research. Sci Eng Ethics (2001) 1.37
Policy issues in the private health sector: examples from long-term care in the U.K. Soc Sci Med (1996) 1.36
Barbourin. A GPIIb-IIIa-specific integrin antagonist from the venom of Sistrurus m. barbouri. J Biol Chem (1991) 1.36
Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in platelets. Blood (1999) 1.35
Mobility of polypeptide chain in the pyruvate dehydrogenase complex revealed by proton NMR. Nature (1981) 1.35
Teenage pregnancy: a comparative study of teenagers choosing termination of pregnancy or antenatal care. J R Soc Med (1995) 1.35
Tyrosine phosphorylation of the beta3 cytoplasmic domain mediates integrin-cytoskeletal interactions. J Biol Chem (1998) 1.34
The catalytic mechanism of cytochrome P450 BM3 involves a 6 A movement of the bound substrate on reduction. Nat Struct Biol (1996) 1.32
A method for purifying the platelet membrane glycoprotein IIb-IIIa complex. Anal Biochem (1985) 1.30
Actin filament content and organization in unstimulated platelets. J Cell Biol (1984) 1.28
The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme. Proc Natl Acad Sci U S A (1996) 1.26
Another source of cellulase. Nature (1969) 1.26
Identification of shc as the primary protein binding to the tyrosine-phosphorylated beta 3 subunit of alpha IIbbeta 3 during outside-in integrin platelet signaling. J Biol Chem (2000) 1.25
Purification and preliminary physicochemical characterization of human platelet membrane glycoprotein V. J Biol Chem (1981) 1.24
Large-scale purification and characterization of dihydrofolate reductase from a methotrexate-resistant strain of Lactobacillus casei. Biochem J (1976) 1.24
Protein-ligand interactions: exchange processes and determination of ligand conformation and protein-ligand contacts. Methods Enzymol (1994) 1.22
Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide. J Biol Chem (1991) 1.22
Reconstitution of the purified platelet fibrinogen receptor. Fibrinogen binding properties of the glycoprotein IIb-IIIa complex. J Biol Chem (1985) 1.22
Direct measurement of the pK values of an alkaline Bohr group in human hemoglobin. Proc Natl Acad Sci U S A (1973) 1.21
Nuclear magnetic resonance studies of the structure and binding sites of enzymes. 8. Inhibitor binding to ribonuclease. J Mol Biol (1969) 1.21
Structure revision of the antibiotic echinomycin. J Am Chem Soc (1975) 1.21
Platelet membrane glycoprotein IIb-IIIa complex incorporated into phospholipid vesicles. Preparation and morphology. J Biol Chem (1985) 1.19
Limited proteolysis and proton n.m.r. spectroscopy of the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli. Biochem J (1981) 1.18
Solution structures of nisin A and its two major degradation products determined by n.m.r. Biochem J (1992) 1.16
Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem (1987) 1.16
Organization of the cytoskeleton in resting, discoid platelets: preservation of actin filaments by a modified fixation that prevents osmium damage. J Cell Biol (1985) 1.16
Polymerization and organization of actin filaments within platelets. Semin Hematol (1983) 1.16
Characterization of covalent adriamycin-DNA adducts. Proc Natl Acad Sci U S A (1998) 1.16
Thrombin substrates and the proteolytic site of thrombin action on human-platelet plasma membranes. Biochim Biophys Acta (1974) 1.15
Molecular differences of exposed surface proteins on thrombasthenic platelet plasma membranes. Nature (1975) 1.13
Stopped-flow kinetic studies of flavin reduction in human cytochrome P450 reductase and its component domains. Biochemistry (2001) 1.13
Platelet plasma membrane glycoproteins. Identification of a proteolytic substrate for thrombin. Biochem Biophys Res Commun (1977) 1.13
The solution structure of the bovine S100B protein dimer in the calcium-free state. Structure (1996) 1.12
The enzymic conversion of linoleic acid into 9-(nona-1',3'-dienoxy)non-8-enoic acid, a novel unsaturated ether derivative isolated from homogenates of Solanum tuberosum tubers. Biochem J (1972) 1.12
Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. J Biol Chem (2001) 1.12
Conformational studies of oxytocin and lysine vasopressin in aqueous solution using high resolution NMR spectroscopy. Nat New Biol (1971) 1.11
cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins. J Biol Chem (1991) 1.11
Role of transmembrane pH gradient and membrane binding in nisin pore formation. J Bacteriol (1997) 1.11
Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 A resolution. Protein Sci (1999) 1.10
An evaluation of membrane glycoproteins in platelet adhesion and aggregation. Prog Hemost Thromb (1980) 1.10
Fibrinogen binding to human platelet plasma membranes. Identification of two steps requiring divalent cations. J Biol Chem (1983) 1.10
Molecular analysis of the regulation of nisin immunity. Microbiology (1996) 1.10
Structure-activity relationships in the peptide antibiotic nisin: antibacterial activity of fragments of nisin. FEBS Lett (1996) 1.08
A model for human cytochrome P450 2D6 based on homology modeling and NMR studies of substrate binding. Biochemistry (1996) 1.08
Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI. J Mol Biol (2001) 1.08
Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells. J Cell Biol (1991) 1.07
Platelet plasma membrane lectin activity. Biochem Biophys Res Commun (1977) 1.07
Calcium cation regulation of glycoprotein IIb-IIIa complex formation in platelet plasma membranes. J Biol Chem (1983) 1.07
Fibronectin-binding properties of the purified platelet glycoprotein IIb-IIIa complex. J Biol Chem (1986) 1.07
Aging trends--Singapore. J Cross Cult Gerontol (1995) 1.07
Increased thrombin responsiveness in platelets from mice lacking glycoprotein V. Proc Natl Acad Sci U S A (1999) 1.06
A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm. Structure (1997) 1.06
A kinetic study of wild-type and mutant dihydrofolate reductases from Lactobacillus casei. Biochemistry (1989) 1.06
Effectiveness of manipulative physiotherapy for the treatment of a neurogenic cervicobrachial pain syndrome: a single case study -- experimental design. Man Ther (2002) 1.05
alpha-Actinin deficiency in thrombasthenia: possible identity of alpha-actinin and glycoprotein III. Am J Pathol (1979) 1.05