Vitamin K-dependent carboxylase: increased activity in a hypoprothrombinemia state.

PubWeight™: 0.78‹?›

🔗 View Article (PMID 742892)

Published in Arch Biochem Biophys on December 01, 1978

Authors

D V Shah, J W Suttie

Articles by these authors

Vitamin K-dependent formation of gamma-carboxyglutamic acid. Annu Rev Biochem (1977) 2.10

Vitamin K-dependent carboxylase. Annu Rev Biochem (1985) 1.74

A new carboxylation reaction. The vitamin K-dependent incorporation of H-14-CO3- into prothrombin. J Biol Chem (1975) 1.71

Mechanism of action of vitamin K: synthesis of gamma-carboxyglutamic acid. CRC Crit Rev Biochem (1980) 1.68

A new vitamin K-dependent protein. A phospholipid-binding zymogen of a serine esterase. J Biol Chem (1976) 1.64

Mechanism of coumarin action: significance of vitamin K epoxide reductase inhibition. Biochemistry (1978) 1.63

Prothrombin structure, activation, and biosynthesis. Physiol Rev (1977) 1.61

Vitamin K-dependent carboxylase. Requirements of the rat liver microsomal enzyme system. J Biol Chem (1976) 1.53

Dietary intake and adequacy of vitamin K. J Nutr (1998) 1.52

Vitamin K requirement and warfarin tolerance in the hamster. Proc Soc Exp Biol Med (1975) 1.39

Echinaforce and other Echinacea fresh plant preparations in the treatment of the common cold. A randomized, placebo controlled, double-blind clinical trial. Phytomedicine (1999) 1.30

Vitamin K-dependent carboxylase. Control of enzyme activity by the "propeptide" region of factor X. J Biol Chem (1987) 1.28

The mode of action of vitamin K. Isolation of a peptide containing the vitamin K-dependent portion of prothrombin. Proc Natl Acad Sci U S A (1973) 1.26

The purification and properties of an abnormal prothrombin protein produced by dicumarol-treated cows. A comparison to normal prothrombin. J Biol Chem (1972) 1.26

Mode of action of vitamin K. Calcium binding properties of bovine prothrombin. Biochemistry (1972) 1.22

Vitamin K-dependent carboxylase. Solubilization and properties. J Biol Chem (1976) 1.20

Vitamin K-dependent carboxylase. Development of a peptide substrate. J Biol Chem (1976) 1.20

Vitamin K status of lactating mothers, human milk, and breast-feeding infants. Pediatrics (1991) 1.17

Evidence that warfarin anticoagulant action involves two distinct reductase activities. J Biol Chem (1982) 1.15

Effect of a short period of fluoride ingestion on dental fluorosis in cattle. Am J Vet Res (1971) 1.15

Vitamin K-dependent carboxylase. Stoichiometry of carboxylation and vitamin K 2,3-epoxide formation. J Biol Chem (1981) 1.10

Vitamin K-dependent carboxylase: requirements for carboxylation of soluble peptide and substrate specificity. Biochem Biophys Res Commun (1979) 1.09

Association of congenital deficiency of multiple vitamin K-dependent coagulation factors and the phenotype of the warfarin embryopathy: clues to the mechanism of teratogenicity of coumarin derivatives. Am J Hum Genet (1987) 1.08

Vitamin K-dependent carboxylase: utilization of decarboxylated bone Gla protein and matrix Gla protein as substrates. Biochim Biophys Acta (1991) 1.07

The functional significance of vitamin K action. Difference in phospholipid binding between normal and abnormal prothrombin. J Biol Chem (1975) 1.07

Conversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteria. J Nutr (1998) 1.05

Vitamin K nutrition and osteoporosis. J Nutr (1995) 1.05

Effect of dietary fluoride on the pattern of food intake in the rat and the development of a programmed pellet dispenser. J Nutr (1968) 1.04

Mechanism of action of vitamin K: demonstration of a liver precursor of prothrombin. Science (1973) 1.00

Warfarin metabolism and vitamin K requirement in the warfarin-resistant rat. Am J Physiol (1969) 0.99

Vitamin K dependent carboxylase: subcellular location of the carboxylase and enzymes involved in vitamin K metabolism in rat liver. Biochemistry (1980) 0.98

Mechanism of coumarin action: sensitivity of vitamin K metabolizing enzymes of normal and warfarin-resistant rat liver. Biochemistry (1982) 0.97

Inhibition of vitamin K-dependent carboxylase in vitro by cefamandole and its structural analogs. J Infect Dis (1983) 0.96

Mechanism of action of vitamin K: evidence for the conversion of a precursor protein to prothrombin in the rat. Proc Natl Acad Sci U S A (1971) 0.96

Vitamin K supplementation reduces serum concentrations of under-gamma-carboxylated osteocalcin in healthy young and elderly adults. Am J Clin Nutr (2000) 0.96

Vitamin K and gamma-carboxyglutamate biosynthesis. Vitam Horm (1977) 0.95

Relationship between vitamin K-dependent carboxylation and vitamin K epoxidation. Fed Proc (1978) 0.94

Recent advances in hepatic vitamin K metabolism and function. Hepatology (1987) 0.94

The vitamin K dependent, in vitro production of prothrombin. Biochem Biophys Res Commun (1974) 0.93

Vitamin K-dependent carboxylase: evidence for a hydroperoxide intermediate in the reaction. Proc Natl Acad Sci U S A (1978) 0.93

Relationship of dithiothreitol-dependent microsomal vitamin K quinone and vitamin K epoxide reductases inhibition of epoxide reduction by vitamin K quinone. Biochim Biophys Acta (1984) 0.93

Purification of an apparent rat liver prothrombin precursor: characterization and comparison to normal rat prothrombin. Biochemistry (1975) 0.93

Vitamin K-dependent carboxylase: purification of the rat liver microsomal enzyme. Arch Biochem Biophys (1980) 0.93

Solubilization and characterization of vitamin K epoxide reductase from normal and warfarin-resistant rat liver microsomes. Arch Biochem Biophys (1984) 0.92

Vitamin K-dependent carboxylase: structural requirements for propeptide activation. Biochim Biophys Acta (1990) 0.92

Assessment of vitamin K status in human subjects administered "minidose" warfarin. Am J Clin Nutr (1996) 0.90

Vitamin K-dependent carboxylase. Demonstration of a vitamin K- and O2-dependent exchange of 3H from 3H2O into glutamic acid residues. J Biol Chem (1983) 0.90

Vitamin K-dependent carboxylation and vitamin K epoxidation. Evidence that the warfarin-sensitive microsomal NAD(P)H dehydrogenase reduces vitamin K1 in these reactions. Biochem J (1981) 0.89

Mechanism of the abnormal vitamin K-dependent gamma-carboxylation process in human hepatocellular carcinomas. Cancer (1994) 0.89

The carbohydrate of bovine prothrombin. Partial structural determination demonstrating the presence of -galactose residues. J Biol Chem (1972) 0.89

Vitamin K epoxidase: properties and relationship to prothrombin synthesis. Biochemistry (1977) 0.89

Vitamin K deficiency from dietary vitamin K restriction in humans. Am J Clin Nutr (1988) 0.89

Effect of N-methyl-thiotetrazole on rat liver microsomal vitamin K-dependent carboxylation. Biochem Pharmacol (1986) 0.88

Recent developments in understanding the mechanism of vitamin K and vitamin K-antagonist drug action and the consequences of vitamin K action in blood coagulation. Prog Hematol (1977) 0.88

Purification and identification of bovine liver gamma-carboxylase. Proc Natl Acad Sci U S A (1992) 0.87

Vitamin K epoxidase: dependence of epoxidase activity on substrates of the vitamin K-dependent carboxylation reaction. FEBS Lett (1980) 0.87

Improving the vitamin K status of breastfeeding infants with maternal vitamin K supplements. Pediatrics (1997) 0.87

Vitamin K dependent in vitro production of prothrombin. Biochemistry (1982) 0.87

Conversion of 14C-labeled geranylgeranyl pyrophosphate to phytoene by a soluble tomato plastid enzyme system. Arch Biochem Biophys (1968) 0.87

Effects of a vitamin K-deficient diet and antibiotics in normal human volunteers. J Lab Clin Med (1987) 0.86

Plasma abnormal prothrombin and microsomal prothrombin precursor in various species (38492). Proc Soc Exp Biol Med (1975) 0.86

Intake, serum concentrations, and urinary excretion of manganese by adult males. Am J Clin Nutr (1990) 0.86

Vitamin K-dependent carboxylase: partial purification of the enzyme by antibody affinity techniques. Thromb Res (1989) 0.85

Report of Workshop on expression of vitamin K-dependent proteins in bacterial and mammalian cells, Madison, Wisconsin, USA, April 1986. Thromb Res (1986) 0.85

Hereditary deficiency of all vitamin K-dependent procoagulants and anticoagulants. Br J Haematol (1990) 0.85

Rat prothrombin: purification, characterization, and activation. Arch Biochem Biophys (1976) 0.85

Electron probe microanalysis of fluorotic bovine teeth. Am J Vet Res (1978) 0.84

Vitamin K status of premature infants: implications for current recommendations. Pediatrics (2001) 0.84

The effect of cycloheximide administration on vitamin K-stimulated prothrombin formation. Arch Biochem Biophys (1970) 0.84

Comparative metabolism and requirement of vitamin K in chicks and rats. J Nutr (1992) 0.84

Comparison of phylloquinone bioavailability from food sources or a supplement in human subjects. J Nutr (1999) 0.84

Clinical profile of diseases causing chronic airflow limitation in a tertiary care centre in India. J Assoc Physicians India (2007) 0.83

Prothrombin biosynthesis: characterization of processing events in rat liver microsomes. Biochemistry (1985) 0.83

Formation of hydroxyvitamin K by vitamin K epoxide reductase of warfarin-resistant rats. J Biol Chem (1983) 0.83

Multi-site-specificity of the vitamin K-dependent carboxylase: in vitro carboxylation of des-gamma-carboxylated bone Gla protein and Des-gamma-carboxylated pro bone Gla protein. Biochemistry (1995) 0.83

Vitamin K status influences brain sulfatide metabolism in young mice and rats. J Nutr (1996) 0.83

Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition site. Proc Natl Acad Sci U S A (1987) 0.82

Effect of N-methyl-thiotetrazole on vitamin K epoxide reductase. Thromb Res (1986) 0.82

Metabolism and properties of a liver precursor to prothrombin. Vitam Horm (1974) 0.82

Synthesis of peptide analogues of prothrombin precursor sequence 5-9. Substrate specificity of vitamin K dependent carboxylase. J Med Chem (1981) 0.82

Vitamin K-dependent carboxylase: effect of Mn2+ and other divalent cations. FEBS Lett (1980) 0.82

Vitamin K epoxide and quinone reductase activities. Evidence for reduction by a common enzyme. Biochem Pharmacol (1990) 0.82

Effect of various intakes of phylloquinone on signs of vitamin K deficiency and serum and liver phylloquinone concentrations in the rat. J Nutr (1989) 0.82

Recent findings in understanding the biological function of vitamin K. Med Biol (1982) 0.82

Evidence for a lack of an effect of dietary fluoride level on reproduction in mice. J Nutr (1976) 0.82

Abnormal prothrombin in the vitamin K-deficient rat. Thromb Res (1984) 0.81

The metabolic role of vitamin K. Fed Proc (1980) 0.81

Formation of 3-hydroxy-2,3-dihydrovitamin K1 in vivo: relationship to vitamin K epoxide reductase and warfarin resistance. J Nutr (1984) 0.81

Vitamin K status of free-living subjects consuming olestra. Am J Clin Nutr (1991) 0.81

Vitamin K-dependent carboxylase: influence of the "propeptide" region on enzyme activity. Arch Biochem Biophys (1989) 0.81

Properties of asialo and aglycoprothrombin. Biochem Biophys Res Commun (1971) 0.80

A rat liver protein with potential thrombin activity: properties and partial purification. Arch Biochem Biophys (1973) 0.80

Development of a fluoride-resistant strain of L cells: membrane and metabolic characteristics. Am J Physiol (1972) 0.80

Metabolism and transport of gamma-carboxyglutamic acid. Biochim Biophys Acta (1978) 0.80

Warfarin resistance in a Chicago strain of rats. Biochem Pharmacol (1990) 0.80