Published in Proc Natl Acad Sci U S A on November 21, 1995
The Microbial Rosetta Stone Database: a compilation of global and emerging infectious microorganisms and bioterrorist threat agents. BMC Microbiol (2005) 1.73
Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines. Proc Natl Acad Sci U S A (1997) 1.47
Activation of bovine lymphocyte subpopulations by staphylococcal enterotoxin C. Infect Immun (1998) 1.09
Inhibition of squamous cancer growth in a mouse model by Staphylococcal enterotoxin B-triggered Th9 cell expansion. Cell Mol Immunol (2015) 0.78
Interleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB). Proc Natl Acad Sci U S A (1998) 0.77
The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell (1989) 7.02
A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry (1983) 6.38
Programmed cell death and extrathymic reduction of Vbeta8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature (1991) 5.56
V beta-specific stimulation of human T cells by staphylococcal toxins. Science (1989) 5.34
The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity (1995) 3.99
Superantigens and their potential role in human disease. Adv Immunol (1993) 3.88
Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association. Science (1991) 3.84
Clonal anergy induced in mature V beta 6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells. Nature (1989) 3.44
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature (1994) 3.36
Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature (1994) 3.31
Programmed cell death in the immune system. Adv Immunol (1991) 3.02
Biological effects of staphylococcal enterotoxin A on human peripheral lymphocytes. Infect Immun (1978) 3.01
Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits. Science (1994) 2.65
Selective anergy of V beta 8+,CD4+ T cells in Staphylococcus enterotoxin B-primed mice. J Exp Med (1990) 2.47
Binding of staphylococcal enterotoxin A to accessory cells is a requirement for its ability to activate human T cells. J Immunol (1988) 2.28
Transactivation by AP-1 is a molecular target of T cell clonal anergy. Science (1992) 2.25
Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor. Science (1994) 2.10
Identification and purification of human Stat proteins activated in response to interleukin-2. Immunity (1995) 1.90
Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission. Proc Natl Acad Sci U S A (1995) 1.89
Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes. EMBO J (1994) 1.50
Kinetics of IL-2 and interferon-gamma production, expression of IL-2 receptors, and cell proliferation in human mononuclear cells exposed to staphylococcal enterotoxin A. Cell Immunol (1985) 1.41
Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor. J Exp Med (1992) 1.37
CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. J Exp Med (1992) 1.36
Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways. Proc Natl Acad Sci U S A (1994) 1.33
Induction of specific clonal anergy in human T lymphocytes by Staphylococcus aureus enterotoxins. Proc Natl Acad Sci U S A (1990) 1.30
Differential induction of transcription factors that regulate the interleukin 2 gene during anergy induction and restimulation. J Exp Med (1992) 1.27
Interleukin 2 receptor gamma chain expression on resting and activated lymphoid cells. J Exp Med (1994) 1.25
Stimulation of human naive and memory T helper cells with bacterial superantigen. Naive CD4+45RA+ T cells require a costimulatory signal mediated through the LFA-1/ICAM-1 pathway. J Immunol (1992) 1.17
Toxic shock syndrome toxin-1 induces inositol phospholipid turnover, protein kinase C translocation, and calcium mobilization in human T cells. J Immunol (1988) 1.17
Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn. J Immunol (1992) 1.15
Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes. Eur J Immunol (1994) 1.14
Reduced CD3-mediated protein tyrosine phosphorylation in anergic CD4+ and CD8+ T cells. J Immunol (1993) 1.10
Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice. Proc Natl Acad Sci U S A (1991) 1.04
Altered protein tyrosine phosphorylation in anergic Th1 cells. J Immunol (1993) 1.00
Expression of the IL-2 receptor gamma chain on various populations in human peripheral blood. Int Immunol (1994) 1.00
The HLA-DP polymorphism in Denmark investigated by local and international PLT reagents. Definition of two "new" DP antigens. Tissue Antigens (1986) 0.99
MHC class II molecules regulate growth in human T cells. Exp Clin Immunogenet (1994) 0.98
Signal transduction by microbial superantigens via MHC class II molecules. Immunol Rev (1993) 0.95
Engagement of MHC class II molecules by staphylococcal superantigens activates src-type protein tyrosine kinases. Eur J Immunol (1994) 0.95
Activation with superantigens induces programmed death in antigen-primed CD4+ class II+ major histocompatibility complex T lymphocytes via a CD11a/CD18-dependent mechanism. Eur J Immunol (1993) 0.95
Interleukin-2 (IL-2) induces tyrosine kinase-dependent translocation of active raf-1 from the IL-2 receptor into the cytosol. J Biol Chem (1992) 0.94
Induction of clonal anergy by oral administration of staphylococcal enterotoxin B. Eur J Immunol (1994) 0.92
Co-stimulation with B7 and targeted superantigen is required for MHC class II-independent T-cell proliferation but not cytotoxicity. Immunology (1993) 0.89
MHC class II molecules deliver costimulatory signals in human T cells through a functional linkage with IL-2-receptors. J Immunol (1993) 0.89
Superantigen and HLA-DR ligation induce phospholipase-C gamma 1 activation in class II+ T cells. J Immunol (1992) 0.82
Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies. Eur J Immunol (1991) 0.81
HLA-DR molecules enhance signal transduction through the CD3/Ti complex in activated T cells. Tissue Antigens (1991) 0.77
HL-A antigens and diabetes mellitus. Lancet (1974) 4.42
HL-A antigens and disease. Statistical and genetical considerations. Tissue Antigens (1974) 4.41
HLA and disease 1982--a survey. Immunol Rev (1983) 3.87
Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J Immunol (1995) 3.30
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
HL-A and disease associations--a survey. Transplant Rev (1975) 2.87
A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nat Genet (1999) 2.85
Mice lacking all conventional MHC class II genes. Proc Natl Acad Sci U S A (1999) 2.83
Dual effect of CCR5 delta 32 gene deletion in HIV-1-infected patients. Copenhagen AIDS Study Group. Lancet (1997) 2.70
Mannose-binding lectin polymorphisms and susceptibility to infection in systemic lupus erythematosus. Arthritis Rheum (1999) 2.66
Histocompatibility determinants in multiple sclerosis, with special reference to clinical course. Lancet (1973) 2.41
Increased frequency of homozygosity of abnormal mannan-binding-protein alleles in patients with suspected immunodeficiency. Lancet (1995) 2.31
A new frequent allele is the missing link in the structural polymorphism of the human mannan-binding protein. Immunogenetics (1994) 2.31
Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest (1999) 2.24
Different molecular events result in low protein levels of mannan-binding lectin in populations from southeast Africa and South America. J Immunol (1998) 2.11
HL-A antigens and multiple sclerosis. Lancet (1972) 2.09
MLC typing in juvenile diabetes mellitus and idiopathic Addison's disease. Transplant Rev (1975) 1.97
Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin. Lancet (1997) 1.92
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89
Followup study on patients with Reiter's disease and reactive arthritis, with special reference to HLA-B27. Arthritis Rheum (1982) 1.83
HLA genotype distribution and genetic models of insulin-dependent diabetes mellitus. Ann Hum Genet (1981) 1.78
Genetics of HLA disease association. Annu Rev Genet (1981) 1.74
Human cell-mediated cytotoxicity against modified target cells is restricted by HLA. Nature (1977) 1.69
Studies of the HLA system and insulin-dependent diabetes mellitus. Diabetes Care (1980) 1.63
Association of mannose-binding-lectin deficiency with severe atherosclerosis. Lancet (1998) 1.62
Nomenclature for factors of the HLA system, 2004. Tissue Antigens (2005) 1.57
CC chemokine receptor 5 polymorphism in rheumatoid arthritis. J Rheumatol (1998) 1.50
Dual role of mannan-binding protein in infections: another case of heterosis? Eur J Immunogenet (1994) 1.50
Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis. Tissue Antigens (2004) 1.47
Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines. Proc Natl Acad Sci U S A (1997) 1.47
The HL-A7 histocompatibility antigen in sarcoidosis in relation to tuberculin sensitivity. Tissue Antigens (1975) 1.45
Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells. Leukemia (1999) 1.45
HLA-D and -DR antigens in genetic analysis of insulin dependent diabetes mellitus. Diabetologia (1981) 1.43
Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro. J Cell Biol (1997) 1.42
Endotoxin-stimulated human monocyte secretion of interleukin 1, tumour necrosis factor alpha, and prostaglandin E2 shows stable interindividual differences. Scand J Immunol (1988) 1.40
Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells. Leukemia (2001) 1.40
Nomenclature for factors of the HLA system, 1998. Tissue Antigens (1999) 1.40
[Transplantation. Blood, bone marrow and solid organs]. Ugeskr Laeger (2000) 1.39
Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice. Proc Natl Acad Sci U S A (1998) 1.38
The association of variant mannose-binding lectin genotypes with radiographic outcome in rheumatoid arthritis. Arthritis Rheum (2000) 1.37
Association between HLA-DR2 and production of tumour necrosis factor alpha and interleukin 1 by mononuclear cells activated by lipopolysaccharide. Scand J Immunol (1988) 1.37
HLA--Dw4 and rheumatoid arthritis. Tissue Antigens (1979) 1.36
Diallelic polymorphism may explain variations of the blood concentration of mannan-binding protein in Eskimos, but not in black Africans. Eur J Immunogenet (1992) 1.35
Scandiatransplant: preliminary report of a kidney exchange program. Transplant Proc (1971) 1.32
Kinetics of intraepithelial lymphocytes in the small intestine of thymus-deprived mice and antigen-deprived mice. Anat Rec (1976) 1.29
Long-lived T and B lymphocytes in the bone marrow and thoracic duct lymph of the mouse. Cell Immunol (1975) 1.29
Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter. Am J Pathol (2000) 1.27
STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma. Blood (2001) 1.27
Heterozygous expression of insulin-dependent diabetes mellitus (IDDM) determinants in the HLA system. Am J Hum Genet (1983) 1.25
FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival. Leukemia (2007) 1.24
Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3. Proc Natl Acad Sci U S A (1999) 1.22
Lymphocyte transformation response to pokeweed mitogen as a predictive marker for development of AIDS and AIDS related symptoms in homosexual men with HIV antibodies. Br Med J (Clin Res Ed) (1987) 1.22
Nomenclature for factors of the HLA system, 2000. Tissue Antigens (2001) 1.21
Two edged role of mannose binding lectin in rheumatoid arthritis: a cross sectional study. J Rheumatol (2000) 1.20
HLA and disease. Transplant Proc (1977) 1.19
HL-A in psoriasis vulgaris and in pustular psoriasis--population and family studies. Br J Dermatol (1974) 1.18
Nomenclature for factors of the HLA system, 1996. Tissue Antigens (1997) 1.18
Suppression of parasite-specific response in Plasmodium falciparum malaria. A longitudinal study of blood mononuclear cell proliferation and subset composition. Scand J Immunol (1986) 1.14
Spontaneous human squamous cell carcinomas are killed by a human cytotoxic T lymphocyte clone recognizing a wild-type p53-derived peptide. Proc Natl Acad Sci U S A (1996) 1.14
Small lymphocyte populations in the mouse bone marrow. Cell Tissue Kinet (1973) 1.14
Letter: HL-A and idiopathic Addison's disease. Lancet (1974) 1.14
Interleukin-2 induces tyrosine phosphorylation and nuclear translocation of stat3 in human T lymphocytes. Eur J Immunol (1994) 1.14
The germline repertoire of T-cell receptor beta chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis. Immunogenetics (1990) 1.13
An HLA map of Europe. Hum Hered (1978) 1.13
Inhibition of T cell proliferation by selective block of Ca(2+)-activated K(+) channels. Proc Natl Acad Sci U S A (1999) 1.13
Proliferative kinetics of large and small intraepithelial lymphocytes in the small intestine of the mouse. Am J Anat (1976) 1.12
HL-A antigens and diseases. I. Multiple sclerosis. Tissue Antigens (1973) 1.11
Compromised virus control and augmented perforin-mediated immunopathology in IFN-gamma-deficient mice infected with lymphocytic choriomeningitis virus. J Immunol (1999) 1.11
The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis. Genes Immun (2001) 1.11
MHC class II ligation induces CD58 (LFA-3)-mediated adhesion in human T cells. Exp Clin Immunogenet (1998) 1.10
Lymphocyte transformation and delayed hypersensitivity in Crohn's disease. Scand J Gastroenterol (1972) 1.10
IL-2 and IL-15 regulate CD154 expression on activated CD4 T cells. J Immunol (2000) 1.08
HLA associations in insulin-dependent diabetes: search for heterogeneity in different groups of patients from a homogeneous population. Tissue Antigens (1986) 1.08
The genetic susceptibility to insulin-dependent diabetes mellitus: combined segregation and linkage analysis. Genet Epidemiol (1985) 1.08
Letter: Lack of antigen response to myxoviruses in multiple sclerosis. Lancet (1973) 1.08
Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentrations. Clin Exp Immunol (1992) 1.08
Nomenclature for factors of the HLA system, 2000. Eur J Immunogenet (2001) 1.08
Letter: Salmonella arthritis and HL-A27. Lancet (1974) 1.07
Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome. Leukemia (2008) 1.07
Genetic studies of insulin-dependent diabetes mellitus: segregation and linkage analyses. Tissue Antigens (1982) 1.06
Importance of HLA-D antigens for the cooperation between human monocytes and T lymphocytes. Eur J Immunol (1978) 1.06
Genetics of the human HL-A transplantation system. Nature (1968) 1.06
NcoI restriction fragment length polymorphism (RFLP) of the tumour necrosis factor (TNF alpha) region in primary biliary cirrhosis and in healthy Danes. Scand J Immunol (1989) 1.06
Subtractive isolation of phage-displayed single-chain antibodies to thymic stromal cells by using intact thymic fragments. Proc Natl Acad Sci U S A (1997) 1.05
Detection of HLA-D/DR-related DNA polymorphism in HLA-D homozygous typing cells. Proc Natl Acad Sci U S A (1983) 1.05
Regulatory T cells and immunodeficiency in mycosis fungoides and Sézary syndrome. Leukemia (2011) 1.05