The pore dimensions of gramicidin A.

Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design. Protein Sci (1998) 7.03

Principles of activation and permeation in an anion-selective Cys-loop receptor. Nature (2011) 5.93

Protein clefts in molecular recognition and function. Protein Sci (1996) 4.20

Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature (2009) 4.18

Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature (2012) 2.97

Gating of MscL studied by steered molecular dynamics. Biophys J (2003) 2.91

The structure of phospholamban pentamer reveals a channel-like architecture in membranes. Proc Natl Acad Sci U S A (2005) 2.76

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. Nat Struct Biol (1999) 2.75

Simulations of ion permeation through a potassium channel: molecular dynamics of KcsA in a phospholipid bilayer. Biophys J (2000) 2.69

Buried waters and internal cavities in monomeric proteins. Protein Sci (1994) 2.30

Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance. Proc Natl Acad Sci U S A (2009) 2.28

A novel method for structure-based prediction of ion channel conductance properties. Biophys J (1997) 2.11

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution. Nature (2014) 2.10

An alamethicin channel in a lipid bilayer: molecular dynamics simulations. Biophys J (1999) 2.01

Molecular dynamics study of gating in the mechanosensitive channel of small conductance MscS. Biophys J (2004) 2.00

Structural determinants of MscL gating studied by molecular dynamics simulations. Biophys J (2001) 1.96

Proton transport behavior through the influenza A M2 channel: insights from molecular simulation. Biophys J (2007) 1.96

Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus. Proc Natl Acad Sci U S A (2009) 1.93

Ion permeation through the alpha-hemolysin channel: theoretical studies based on Brownian dynamics and Poisson-Nernst-Plank electrodiffusion theory. Biophys J (2004) 1.91

The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit. EMBO J (2013) 1.86

Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A. Proc Natl Acad Sci U S A (2005) 1.81

Ion conduction through MscS as determined by electrophysiology and simulation. Biophys J (2006) 1.80

High-resolution structure of the open NaK channel. Nat Struct Mol Biol (2008) 1.79

Statistical mechanical equilibrium theory of selective ion channels. Biophys J (1999) 1.78

Molecular dynamics simulations of water within models of ion channels. Biophys J (1996) 1.72

Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum. Nat Struct Mol Biol (2008) 1.68

High-resolution x-ray structure of human aquaporin 5. Proc Natl Acad Sci U S A (2008) 1.66

Structural analysis of CsoS1A and the protein shell of the Halothiobacillus neapolitanus carboxysome. PLoS Biol (2007) 1.57

Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method. Proc Natl Acad Sci U S A (2011) 1.57

A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat Struct Mol Biol (2012) 1.56

How do SET-domain protein lysine methyltransferases achieve the methylation state specificity? Revisited by Ab initio QM/MM molecular dynamics simulations. J Am Chem Soc (2008) 1.48

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome. Proc Natl Acad Sci U S A (2010) 1.48

Exploring models of the influenza A M2 channel: MD simulations in a phospholipid bilayer. Biophys J (2000) 1.48

Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process. Biophys J (2007) 1.44

ENaC structure and function in the wake of a resolved structure of a family member. Am J Physiol Renal Physiol (2011) 1.44

K(+) versus Na(+) ions in a K channel selectivity filter: a simulation study. Biophys J (2002) 1.42

Homology modeling and molecular dynamics simulation studies of an inward rectifier potassium channel. Biophys J (2000) 1.42

Crystal structures of the OmpF porin: function in a colicin translocon. EMBO J (2008) 1.41

Parallel helix bundles and ion channels: molecular modeling via simulated annealing and restrained molecular dynamics. Biophys J (1994) 1.41

Crystal structure of a yeast aquaporin at 1.15 angstrom reveals a novel gating mechanism. PLoS Biol (2009) 1.41

Common mechanism of pore opening shared by five different potassium channels. Biophys J (2006) 1.40

Homology modeling of representative subfamilies of Arabidopsis major intrinsic proteins. Classification based on the aromatic/arginine selectivity filter. Plant Physiol (2004) 1.38

A semi-microscopic Monte Carlo study of permeation energetics in a gramicidin-like channel: the origin of cation selectivity. Biophys J (1996) 1.38

Dynamic properties of Na+ ions in models of ion channels: a molecular dynamics study. Biophys J (1998) 1.37

Solution structure and functional analysis of the influenza B proton channel. Nat Struct Mol Biol (2009) 1.37

Soluble amyloid beta-oligomers affect dielectric membrane properties by bilayer insertion and domain formation: implications for cell toxicity. Biophys J (2008) 1.36

Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel. Nature (2009) 1.35

Structural basis of aquaporin inhibition by mercury. J Mol Biol (2007) 1.35

PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure. PLoS Comput Biol (2009) 1.35

The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics. Biophys J (1996) 1.34

Gating movement of acetylcholine receptor caught by plunge-freezing. J Mol Biol (2012) 1.33

Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels. Biophys J (2008) 1.30

MolAxis: efficient and accurate identification of channels in macromolecules. Proteins (2008) 1.30

Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins. Proc Natl Acad Sci U S A (2011) 1.30

An iris-like mechanism of pore dilation in the CorA magnesium transport system. Biophys J (2010) 1.29

OmpA: a pore or not a pore? Simulation and modeling studies. Biophys J (2002) 1.28

Molecular dynamics studies of the archaeal translocon. Biophys J (2006) 1.27

Crystal structure of Escherichia coli PNPase: central channel residues are involved in processive RNA degradation. RNA (2008) 1.25

Analysis and evaluation of channel models: simulations of alamethicin. Biophys J (2002) 1.25

Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature (2014) 1.23

Single-channel water permeabilities of Escherichia coli aquaporins AqpZ and GlpF. Biophys J (2006) 1.21

An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation. J Gen Physiol (2010) 1.20

Modeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologue. PLoS Comput Biol (2010) 1.20

Sugar binding and protein conformational changes in lactose permease. Biophys J (2006) 1.20

Ammonium ion transport by the AMT/Rh homologue LeAMT1;1. Biochem J (2006) 1.20

Potassium channel, ions, and water: simulation studies based on the high resolution X-ray structure of KcsA. Biophys J (2003) 1.18

Probing the role of the ATP-operated clamp in the strand-passage reaction of DNA gyrase. Nucleic Acids Res (1996) 1.18

Hierarchical approach to predicting permeation in ion channels. Biophys J (2001) 1.18

Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels. Biophys J (2009) 1.18

Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants. Biophys J (2003) 1.17

Open-state models of a potassium channel. Biophys J (2002) 1.17

Sugar transport across lactose permease probed by steered molecular dynamics. Biophys J (2007) 1.16

Transbilayer pores formed by beta-barrels: molecular modeling of pore structures and properties. Biophys J (1995) 1.16

Intrinsic rectification of ion flux in alamethicin channels: studies with an alamethicin dimer. Biophys J (1997) 1.16

Gauging a hydrocarbon ruler by an intrinsic exciton probe. Biochemistry (2007) 1.14

Mechanical coupling maintains the fidelity of NMDA receptor-mediated currents. Nat Neurosci (2014) 1.14

Molecular dynamics study of MscL interactions with a curved lipid bilayer. Biophys J (2006) 1.12

Ammonium recruitment and ammonia transport by E. coli ammonia channel AmtB. Biophys J (2006) 1.12

Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology. J Phys Chem B (2012) 1.11

Probing the periplasmic-open state of lactose permease in response to sugar binding and proton translocation. J Mol Biol (2010) 1.11

A computer simulation study of the hydrated proton in a synthetic proton channel. Biophys J (2003) 1.11

MolAxis: a server for identification of channels in macromolecules. Nucleic Acids Res (2008) 1.10

Annular structures as intermediates in fibril formation of Alzheimer Abeta17-42. J Phys Chem B (2008) 1.10

An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein. Protein Sci (2015) 1.09

Solvation, water permeation, and ionic selectivity of a putative model for the pore region of the voltage-gated sodium channel. Biophys J (1996) 1.08

Charge delocalization in proton channels, I: the aquaporin channels and proton blockage. Biophys J (2006) 1.08

Structural convergence among diverse, toxic beta-sheet ion channels. J Phys Chem B (2010) 1.08

POVME 2.0: An Enhanced Tool for Determining Pocket Shape and Volume Characteristics. J Chem Theory Comput (2014) 1.08

The influence of amino acid protonation states on molecular dynamics simulations of the bacterial porin OmpF. Biophys J (2005) 1.07

Structural dynamics of the magnesium-bound conformation of CorA in a lipid bilayer. Structure (2010) 1.07

Molecular dynamics study of water and Na+ ions in models of the pore region of the nicotinic acetylcholine receptor. Biophys J (1997) 1.07

Structural context shapes the aquaporin selectivity filter. Proc Natl Acad Sci U S A (2010) 1.06

Structural basis of GDP release and gating in G protein coupled Fe2+ transport. EMBO J (2009) 1.05

Mechanics of channel gating of the nicotinic acetylcholine receptor. PLoS Comput Biol (2008) 1.05

Toward theoretical analysis of long-range proton transfer kinetics in biomolecular pumps. J Phys Chem A (2006) 1.04

Solution structure and lipid binding of a nonspecific lipid transfer protein extracted from maize seeds. Protein Sci (1996) 1.03

Structures of sequential open states in a symmetrical opening transition of the TolC exit duct. Proc Natl Acad Sci U S A (2011) 1.03

The alpha-5 segment of Bacillus thuringiensis delta-endotoxin: in vitro activity, ion channel formation and molecular modelling. Biochem J (1994) 1.01

Formation of ion channels in lipid bilayers by a peptide with the predicted transmembrane sequence of botulinum neurotoxin A. Protein Sci (1995) 1.00

Unbiased simulations reveal the inward-facing conformation of the human serotonin transporter and Na(+) ion release. PLoS Comput Biol (2011) 1.00

The Protein Data Bank: a computer-based archival file for macromolecular structures. J Mol Biol (1977) 90.57

Optimization by simulated annealing. Science (1983) 71.02

Solvent-accessible surfaces of proteins and nucleic acids. Science (1983) 11.29

The gramicidin A transmembrane channel: a proposed pi(L,D) helix. Proc Natl Acad Sci U S A (1971) 7.74

Ion transfer across lipid membranes in the presence of gramicidin A. II. The ion selectivity. Biochim Biophys Acta (1972) 4.35

1H-NMR study of gramicidin A transmembrane ion channel. Head-to-head right-handed, single-stranded helices. FEBS Lett (1985) 3.65

GRAMICIDIN A. V. THE STRUCTURE OF VALINE- AND ISOLEUCINE-GRAMICIDIN A. J Am Chem Soc (1965) 3.55

The dimeric nature of the gramicidin A transmembrane channel: conductance and fluorescence energy transfer studies of hybrid channels. J Mol Biol (1977) 3.27

Gramicidin channels. Annu Rev Physiol (1984) 3.00

The conformation of gramicidin A. Biochemistry (1974) 2.99

POCKET: a computer graphics method for identifying and displaying protein cavities and their surrounding amino acids. J Mol Graph (1992) 2.57

Conformation of the gramicidin A transmembrane channel: A 13C nuclear magnetic resonance study of 13C-enriched gramicidin in phosphatidylcholine vesicles. J Mol Biol (1980) 2.36

The gramicidin pore: crystal structure of a cesium complex. Science (1988) 2.22

Gramicidin, valinomycin, and cation permeability of Streptococcus faecalis. J Bacteriol (1967) 2.19

Three-dimensional structure at 0.86 A of the uncomplexed form of the transmembrane ion channel peptide gramicidin A. Science (1988) 2.11

Energetics of ion permeation through membrane channels. Solvation of Na+ by gramicidin A. Biophys J (1989) 2.07

Ion-water and ion-polypeptide correlations in a gramicidin-like channel. A molecular dynamics study. Biophys J (1990) 1.77

Function of peptide antibiotics in sporulation. Nat New Biol (1972) 1.67

Molecular dynamics computations and solid state nuclear magnetic resonance of the gramicidin cation channel. Biophys J (1991) 1.42

On the supramolecular organization of gramicidin channels. The elementary conducting unit is a dimer. Biophys J (1992) 1.34

Cavity search: an algorithm for the isolation and display of cavity-like binding regions. J Comput Aided Mol Des (1990) 1.31

Monoclinic uncomplexed double-stranded, antiparallel, left-handed beta 5.6-helix (increases decreases beta 5.6) structure of gramicidin A: alternate patterns of helical association and deformation. Proc Natl Acad Sci U S A (1991) 1.25

Ion-bond forms of the gramicidin a transmembrane channel. Biophys J (1984) 1.24

An interaction between gramicidin and the sigma subunit of RNA polymerase. Proc Natl Acad Sci U S A (1982) 1.22

Conformation of peptide chains containing both L- & D-residues. I. Helical structures with alternating L- & D-residues with special reference to the LD-ribbon & the LD-helices. Indian J Biochem Biophys (1972) 1.17

X-ray analysis and protein structure. Cold Spring Harb Symp Quant Biol (1950) 1.13

The permeation properties of small organic cations in gramicidin A channels. Biophys J (1993) 1.09

Gramicidin channel selectivity. Molecular mechanics calculations for formamidinium, guanidinium, and acetamidinium. Biophys J (1992) 1.02

DNA-supercoiling is affected in vitro by the peptide antibiotics tyrocidine and gramicidin. Eur J Biochem (1986) 0.97

Comparison of the effect of linear gramicidin analogues on bacterial sporulation, membrane permeability, and ribonucleic acid polymerase. Biochemistry (1979) 0.95

Effect of linear gramicidin on sporulation and intracellular ATP pools of Bacillus brevis. Arch Microbiol (1985) 0.94

DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data. Nucleic Acids Res (2004) 8.63

Protein secondary structure analyses from circular dichroism spectroscopy: methods and reference databases. Biopolymers (2008) 6.64

HOLE: a program for the analysis of the pore dimensions of ion channel structural models. J Mol Graph (1996) 6.48

Path of the polypeptide in bacteriorhodopsin. Proc Natl Acad Sci U S A (1980) 4.76

DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra. Bioinformatics (2002) 4.01

Model ion channels: gramicidin and alamethicin. J Membr Biol (1992) 2.47

Modelling insecticide-binding sites in the voltage-gated sodium channel. Biochem J (2006) 2.43

A reference database for circular dichroism spectroscopy covering fold and secondary structure space. Bioinformatics (2006) 2.38

Conformation of the gramicidin A transmembrane channel: A 13C nuclear magnetic resonance study of 13C-enriched gramicidin in phosphatidylcholine vesicles. J Mol Biol (1980) 2.36

Buried waters and internal cavities in monomeric proteins. Protein Sci (1994) 2.30

Structure of gramicidin A. Biophys J (1986) 2.12

Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing. Nat Commun (2012) 2.01

Conformation of gramicidin A channel in phospholipid vesicles: a 13C and 19F nuclear magnetic resonance study. Proc Natl Acad Sci U S A (1979) 2.00

CDtool-an integrated software package for circular dichroism spectroscopic data processing, analysis, and archiving. Anal Biochem (2004) 1.96

Distributions of water around amino acid residues in proteins. J Mol Biol (1988) 1.90

Secondary structure and assembly mechanism of an oligomeric channel protein. Biochemistry (1985) 1.90

Modelling protein unfolding: hen egg-white lysozyme. Protein Eng (1997) 1.88

Folding of the mitochondrial proton adenosinetriphosphatase proteolipid channel in phospholipid vesicles. Biochemistry (1982) 1.86

Conformation of gramicidin A in phospholipid vesicles: circular dichroism studies of effects of ion binding, chemical modification, and lipid structure. Biochemistry (1981) 1.78

The Peptaibol Database: a database for sequences and structures of naturally occurring peptaibols. Nucleic Acids Res (2004) 1.68

Differential light scattering and absorption flattening optical effects are minimal in the circular dichroism spectra of small unilamellar vesicles. Biochemistry (1984) 1.62

Differential absorption flattening optical effects are significant in the circular dichroism spectra of large membrane fragments. Biochemistry (1987) 1.61

Modelling of a voltage-dependent Ca2+ channel beta subunit as a basis for understanding its functional properties. FEBS Lett (1999) 1.54

The P23T cataract mutation causes loss of solubility of folded gammaD-crystallin. J Mol Biol (2004) 1.53

Structure and function of voltage-dependent ion channel regulatory beta subunits. Biochemistry (2002) 1.47

Peptaibols: models for ion channels. Biochem Soc Trans (2001) 1.39

Synchrotron radiation circular dichroism spectroscopy of proteins and applications in structural and functional genomics. Chem Soc Rev (2005) 1.37

Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma. J Mol Biol (2010) 1.36

The secondary structure of gap junctions. Influence of isolation methods and proteolysis. J Biol Chem (1990) 1.34

X-ray diffraction studies of the corneal stroma. J Mol Biol (1978) 1.32

Monte Carlo computer simulation of water-amino acid interactions. Proc R Soc Lond B Biol Sci (1982) 1.32

Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein. J Mol Biol (1999) 1.31

Location of the carboxyl terminus of bacteriorhodopsin in purple membrane. Biophys J (1982) 1.30

Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq. Nucleic Acids Res (2011) 1.30

Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channel. Proc Natl Acad Sci U S A (2013) 1.25

Characterization and membrane assembly of the TatA component of the Escherichia coli twin-arginine protein transport system. Biochemistry (2002) 1.24

Ion-bond forms of the gramicidin a transmembrane channel. Biophys J (1984) 1.24

A reference dataset for the analyses of membrane protein secondary structures and transmembrane residues using circular dichroism spectroscopy. Bioinformatics (2011) 1.21

Circular dichroism analyses of membrane proteins: an examination of differential light scattering and absorption flattening effects in large membrane vesicles and membrane sheets. Anal Biochem (1984) 1.19

Role of the C-terminal domain in the structure and function of tetrameric sodium channels. Nat Commun (2013) 1.19

Slow alpha helix formation during folding of a membrane protein. Biochemistry (1997) 1.17

2Struc: the secondary structure server. Bioinformatics (2010) 1.15

Conformation of alamethicin in phospholipid vesicles: implications for insertion models. Proteins (1988) 1.15

Opsin stability and folding: modulation by phospholipid bicelles. J Mol Biol (2007) 1.13

PCDDB: the Protein Circular Dichroism Data Bank, a repository for circular dichroism spectral and metadata. Nucleic Acids Res (2010) 1.12

Interactions of the type III secretion pathway proteins LcrV and LcrG from Yersinia pestis are mediated by coiled-coil domains. J Biol Chem (2002) 1.12

Simplified bacterial "pore" channel provides insight into the assembly, stability, and structure of sodium channels. J Biol Chem (2011) 1.11

Hydrophobic solvation in aqueous trifluoroethanol solution. Biopolymers (1996) 1.11

NaChBac: the long lost sodium channel ancestor. Biochemistry (2011) 1.07

Surface architecture of endospores of the Bacillus cereus/anthracis/thuringiensis family at the subnanometer scale. Proc Natl Acad Sci U S A (2011) 1.07

Swelling studies of bovine corneal stroma without bounding membranes. J Physiol (1980) 1.06

Spectral magnitude effects on the analyses of secondary structure from circular dichroism spectroscopic data. Protein Sci (2005) 1.06

Monte Carlo studies on water in the dCpG/proflavin crystal hydrate. J Biomol Struct Dyn (1983) 1.06

The metastasis-associated extracellular matrix protein osteopontin forms transient structure in ligand interaction sites. Biochemistry (2011) 1.05

Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel. PLoS One (2012) 1.03

A model for Batten disease protein CLN3: functional implications from homology and mutations. FEBS Lett (1996) 1.02

Temperature dependence of the interaction of alamethicin helices in membranes. Biochemistry (1993) 1.02

Synchrotron radiation circular dichroism spectroscopy-defined structure of the C-terminal domain of NaChBac and its role in channel assembly. Proc Natl Acad Sci U S A (2010) 1.02

Gramicidin channel controversy--revisited. Nat Struct Biol (1999) 1.01

Analysis of protein main-chain solvation as a function of secondary structure. J Mol Biol (1991) 1.01

Tetrameric bacterial sodium channels: characterization of structure, stability, and drug binding. Biochemistry (2008) 1.01

Phospholipid chain length alters the equilibrium between pore and channel forms of gramicidin. Faraday Discuss (1998) 1.01

Analysis of peptaibol sequence composition: implications for in vivo synthesis and channel formation. Eur Biophys J (2003) 1.00

The planar distributions of surface proteins and intramembrane particles in Acholeplasma laidlawii are differentially affected by the physical state of membrane lipids. Biochim Biophys Acta (1978) 1.00

Distribution of solvent molecules around apolar side-chains in protein crystals. J Mol Biol (1993) 0.99

Crystal structure of the gramicidin/potassium thiocyanate complex. J Mol Biol (1997) 0.99

A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation. J Biol Chem (2008) 0.98

Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data. BMC Bioinformatics (2006) 0.96

Transmembrane peptide NB of influenza B: a simulation, structure, and conductance study. Biochemistry (2000) 0.96

Conformation of an oligopeptide in phospholipid vesicles. Proc Natl Acad Sci U S A (1979) 0.95

The crystal structure of human endothelin. Nat Struct Biol (1994) 0.94

Solution structure of a parallel left-handed double-helical gramicidin-A determined by 2D 1H NMR. J Mol Biol (1996) 0.94

Charge-transfer transitions in the vacuum-ultraviolet of protein circular dichroism spectra. J Phys Chem B (2008) 0.93

Influence of secondary structure on the hydration of serine, threonine and tyrosine residues in proteins. Protein Eng (1990) 0.93

Competing interactions contributing to alpha-helical stability in aqueous solution. Protein Sci (1995) 0.92

The protein circular dichroism data bank, a Web-based site for access to circular dichroism spectroscopic data. Structure (2010) 0.92

Binding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation. J Biol Chem (2002) 0.92

G219S mutagenesis as a means of stabilizing conformational flexibility in the bacterial sodium channel NaChBac. Mol Membr Biol (2008) 0.92

Modeling and docking the endothelin G-protein-coupled receptor. Biophys J (2000) 0.92

The effects of lipid environment, ion-binding and chemical modifications on the structure of the gramicidin transmembrane channel. Biophys J (1982) 0.91

Evaluation of methods for the prediction of membrane protein secondary structures. Proc Natl Acad Sci U S A (1986) 0.91

Predictive 3D modelling of the interactions of pyrethroids with the voltage-gated sodium channels of ticks and mites. Pest Manag Sci (2013) 0.90

Calcium fluoride micro cells for synchrotron radiation circular dichroism spectroscopy. Appl Spectrosc (2005) 0.90

Thermal and chemical unfolding and refolding of a eukaryotic sodium channel. Biochim Biophys Acta (2009) 0.89

Association of partially folded lens betaB2-crystallins with the alpha-crystallin molecular chaperone. Biochem J (2008) 0.89

Cooperative effects in water-biomolecule crystal systems. Proc Natl Acad Sci U S A (1982) 0.89

Differential lipid dependence of the function of bacterial sodium channels. PLoS One (2013) 0.89

A reference dataset for circular dichroism spectroscopy tailored for the betagamma-crystallin lens proteins. Exp Eye Res (2007) 0.88

Modelling of solvent positions around polar groups in proteins. Protein Eng (1991) 0.88

The influence of lipid state on the planar distribution of membrane proteins in Acholeplasma laidlawii. J Mol Biol (1976) 0.88

Folding factors and partners for the intrinsically disordered protein micro-exon gene 14 (MEG-14). Biophys J (2013) 0.87

The structure and function of antiamoebin I, a proline-rich membrane-active polypeptide. Structure (1998) 0.87

Comparison of lipid/gramicidin dispersions and cocrystals by Raman scattering. Biochemistry (1987) 0.86

Binding of alkaline cations to the double-helical form of gramicidin. Biophys J (1996) 0.86

Hydration of amino acid side chains: dependence on secondary structure. Protein Eng (1992) 0.86

Effects of deglycosylation of sodium channels on their structure and function. Biochemistry (2005) 0.85

Binding of fibronectin to phospholipid vesicles. J Biol Chem (1983) 0.85

Secondary structural analyses of the nicotinic acetylcholine receptor as a test of molecular models. J Biol Chem (1988) 0.85

Solvent interactions with pi ring systems in proteins. Protein Eng (1995) 0.85

Molecular dynamics simulations of dinucleoside and dinucleoside-drug crystal hydrates. J Biomol Struct Dyn (1991) 0.84