Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma.

PubWeight™: 2.05‹?› | Rank: Top 2%

🔗 View Article (PMC 2191482)

Published in J Exp Med on May 01, 1994

Authors

D R Smith1, P J Polverini, S L Kunkel, M B Orringer, R I Whyte, M D Burdick, C A Wilke, R M Strieter

Author Affiliations

1: Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48109-0360.

Articles citing this

Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity. Nat Med (2010) 4.00

Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin. Am J Pathol (2000) 3.18

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med (1995) 2.99

Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Res (2010) 2.61

Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J Clin Invest (1998) 2.42

Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J Clin Invest (1996) 2.20

Interferon-gamma-inducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases. J Exp Med (1996) 2.14

Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. Am J Pathol (2002) 1.96

Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma. Neoplasia (2006) 1.81

Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. Am J Pathol (1998) 1.75

Chemokines as mediators of neovascularization. Arterioscler Thromb Vasc Biol (2008) 1.71

Neutrophil alveolitis in bronchioloalveolar carcinoma: induction by tumor-derived interleukin-8 and relation to clinical outcome. Am J Pathol (1998) 1.66

Interleukin-8/CXCL8 is a growth factor for human lung cancer cells. Br J Cancer (2004) 1.56

Expression of interleukin-8 correlates with angiogenesis, tumorigenicity, and metastasis of human prostate cancer cells implanted orthotopically in nude mice. Neoplasia (2001) 1.52

The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma. J Leukoc Biol (2000) 1.48

CXC chemokines in cancer angiogenesis and metastases. Adv Cancer Res (2010) 1.44

Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma. Clin Cancer Res (2009) 1.43

Chemokines as mediators of angiogenesis. Thromb Haemost (2007) 1.40

Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis. J Exp Med (1997) 1.39

Expression of CXCR1 and CXCR2 receptors in malignant melanoma with different metastatic potential and their role in interleukin-8 (CXCL-8)-mediated modulation of metastatic phenotype. Clin Exp Metastasis (2003) 1.39

Interleukin-8 induces nuclear transcription factor-kappaB through a TRAF6-dependent pathway. J Biol Chem (2004) 1.36

Distinct CXC chemokines mediate tumorigenicity of prostate cancer cells. Am J Pathol (1999) 1.34

Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice. Br J Cancer (1999) 1.26

Pleiotropic effects of CXC chemokines in gastric carcinoma: differences in CXCL8 and CXCL1 expression between diffuse and intestinal types of gastric carcinoma. Clin Exp Immunol (2003) 1.17

The role of chemokines and their receptors in angiogenesis. Cell Mol Life Sci (2011) 1.15

Impact of smoking status on the biological behavior of lung cancer. Surg Today (2007) 1.14

Chemokines as mediators of tumor angiogenesis and neovascularization. Exp Cell Res (2010) 1.11

Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells. Mol Cell Biol (2002) 1.10

Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer. Int J Cancer (2011) 1.08

Airway neutrophilia in stable and bronchiolitis obliterans syndrome patients following lung transplantation. Thorax (2000) 1.06

Autocrine role for interleukin-8 in Bartonella henselae-induced angiogenesis. Infect Immun (2006) 1.03

Monocyte chemotactic protein 1 promotes lung cancer-induced bone resorptive lesions in vivo. Neoplasia (2009) 1.03

Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. Cancer Sci (2008) 1.02

CXC chemokines and chemokine receptors in gastric cancer: from basic findings towards therapeutic targeting. World J Gastroenterol (2014) 1.02

Slit proteins, potential endogenous modulators of inflammation. J Neurovirol (2002) 1.02

Cancer-stromal cell interaction and tumor angiogenesis in gastric cancer. Cancer Microenviron (2009) 1.00

Angiogenesis and lymphangiogenesis of gastric cancer. J Oncol (2010) 0.95

Chemokines, innate and adaptive immunity, and respiratory disease. Eur Respir J (2002) 0.95

Chemokine receptor expression in tumour islets and stroma in non-small cell lung cancer. BMC Cancer (2010) 0.95

The host environment promotes the development of primary and metastatic squamous cell carcinomas that constitutively express proinflammatory cytokines IL-1alpha, IL-6, GM-CSF, and KC. Clin Exp Metastasis (1998) 0.92

Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo. Clin Cancer Res (2007) 0.91

Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic. Am J Pathol (1996) 0.89

Tumour cell lines HT-29 and FaDu produce proinflammatory cytokines and activate neutrophils in vitro: possible applications for neutrophil-based antitumour treatment. Mediators Inflamm (2010) 0.88

3D culture broadly regulates tumor cell hypoxia response and angiogenesis via pro-inflammatory pathways. Biomaterials (2015) 0.85

Intratumoral expression of macrophage migration inhibitory factor is correlated with serum C-reactive protein and interleukin-6 in patients with non-small cell lung cancer. Surg Today (2008) 0.85

Human papillomavirus up-regulates MMP-2 and MMP-9 expression and activity by inducing interleukin-8 in lung adenocarcinomas. PLoS One (2013) 0.85

Clinicopathological and prognostic significance of interleukin-8 expression and its relationship to KRAS mutation in lung adenocarcinoma. Br J Cancer (2014) 0.84

Diversity of the angiogenic phenotype in non-small cell lung cancer. Am J Respir Cell Mol Biol (2006) 0.84

IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells. BMC Cancer (2008) 0.83

Concern Knockdown of aberrantly expressed nuclear localized decorin attenuates tumour angiogenesis related mediators in oral cancer progression model in vitro. Head Neck Oncol (2012) 0.80

Preparation, characterization, and evaluation of antitumor effect of Brucea javanica oil cationic nanoemulsions. Int J Nanomedicine (2016) 0.78

Interleukin-8 in Hodgkin's disease. Preferential expression by reactive cells and association with neutrophil density. Am J Pathol (1996) 0.77

A phase II trial of the BCL-2 homolog domain 3 mimetic AT-101 in combination with docetaxel for recurrent, locally advanced, or metastatic head and neck cancer. Invest New Drugs (2016) 0.77

Modeling head and neck cancer stem cell-mediated tumorigenesis. Cell Mol Life Sci (2016) 0.75

Identification of genes and signaling pathways associated with squamous cell carcinoma by bioinformatics analysis. Oncol Lett (2015) 0.75

Articles cited by this

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest (1989) 10.59

Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science (1992) 7.92

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor. J Exp Med (1988) 7.12

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung. J Clin Invest (1990) 5.21

Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta. Science (1989) 4.99

Activated macrophages induce vascular proliferation. Nature (1977) 3.74

Relation of vascular proliferation to tumor growth. Int Rev Exp Pathol (1976) 3.21

Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8. J Exp Med (1991) 2.96

Monokine-induced neutrophil chemotactic factor gene expression in human fibroblasts. J Biol Chem (1989) 2.43

Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol (1990) 2.25

Structure determination of a human lymphocyte derived neutrophil activating peptide (LYNAP). Biochem Biophys Res Commun (1988) 2.10

Human alveolar macrophage gene expression of interleukin-8 by tumor necrosis factor-alpha, lipopolysaccharide, and interleukin-1 beta. Am J Respir Cell Mol Biol (1990) 1.98

Stimulation of neovascularization by human rheumatoid synovial tissue macrophages. Arthritis Rheum (1986) 1.71

Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. J Immunol (1990) 1.65

Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system. Cancer Res (1992) 1.51

Potent and specific inhibition of IL-8-, IL-1 alpha- and IL-1 beta-induced in vitro human lymphocyte migration by calcium channel antagonists. Biochem Biophys Res Commun (1989) 1.30

Growth stimulation of cultured endothelial cells by tumor cell homogenates. Cancer Res (1976) 1.28

Interleukin-8 stimulates angiogenesis in rats. Inflammation (1993) 1.28

IL-1 and TNF-alpha induction of IL-8 and monocyte chemotactic and activating factor (MCAF) mRNA expression in a human astrocytoma cell line. Immunology (1991) 1.23

Thiol-containing compounds inhibit the production of monocyte/macrophage-derived angiogenic activity. Agents Actions (1991) 1.09

Acquisition of angiogenic capacity and neoplastic transformation in the rat mammary gland. Cancer Res (1978) 1.03

The production of interleukin-1 receptor antagonist by human bronchogenic carcinoma. Am J Pathol (1993) 0.96

Cytokine production by the bladder carcinoma cell line 5637: rapid analysis of mRNA expression levels using a cDNA-PCR procedure. Lymphokine Cytokine Res (1991) 0.96

Growth stimulation of endothelial cells by simultaneous culture with Sarcoma 180 cells in diffusion chambers. Cancer Res (1977) 0.82

Coding region structure of interleukin-8 gene of human lung giant cell carcinoma LU65C cells that produce LUCT/interleukin-8: homogeneity in interleukin-8 genes. Immunol Lett (1990) 0.82

Articles by these authors

Diversity of gene expression in adenocarcinoma of the lung. Proc Natl Acad Sci U S A (2001) 17.36

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest (1989) 10.59

Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science (1992) 7.92

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J Clin Invest (1997) 7.58

Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med (1998) 6.52

Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups. Lancet (1993) 6.39

Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma. J Clin Oncol (2001) 6.07

Biological action of leptin as an angiogenic factor. Science (1998) 6.02

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci U S A (1990) 5.26

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-alpha. Nature (1987) 5.24

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung. J Clin Invest (1990) 5.21

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proc Natl Acad Sci U S A (1989) 5.07

Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta. Science (1989) 4.99

The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem (1995) 4.77

Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation (1983) 4.01

Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science (1991) 3.96

Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma. N Engl J Med (1997) 3.90

Activated macrophages induce vascular proliferation. Nature (1977) 3.74

Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis. J Clin Invest (1992) 3.72

Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline. Biochem Biophys Res Commun (1988) 3.63

Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung. Exp Lung Res (1991) 3.49

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin Invest (1990) 3.39

The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity. J Immunol (2000) 3.26

Esophagectomy without thoracotomy. J Thorac Cardiovasc Surg (1978) 3.26

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest (1999) 3.21

CXC chemokines in angiogenesis. J Leukoc Biol (2000) 3.17

Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity. J Cell Biol (1993) 3.15

Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol (1999) 3.15

Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1. Nature (1995) 3.07

Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol (1998) 3.05

Tumor necrosis factor stimulates interleukin-1 and prostaglandin E2 production in resting macrophages. Biochem Biophys Res Commun (1986) 2.96

Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis. Science (1995) 2.88

Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44. J Clin Invest (1996) 2.86

Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am J Respir Crit Care Med (1996) 2.81

Purification and chemical characterization of the heat-labile enterotoxin produced by enterotoxigenic Escherichia coli. Infect Immun (1979) 2.80

Incidence and distribution of distant metastases from newly diagnosed esophageal carcinoma. Cancer (1995) 2.73

Neutralization of macrophage inflammatory protein-2 attenuates neutrophil recruitment and bacterial clearance in murine Klebsiella pneumonia. J Infect Dis (1996) 2.72

CXC chemokine receptor CXCR2 is essential for protective innate host response in murine Pseudomonas aeruginosa pneumonia. Infect Immun (2000) 2.66

Engineering and characterization of functional human microvessels in immunodeficient mice. Lab Invest (2001) 2.61

Esophagectomy without thoracotomy: a dangerous operation? J Thorac Cardiovasc Surg (1983) 2.61

Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2. J Clin Invest (1995) 2.59

Lung cytokine production in bleomycin-induced pulmonary fibrosis. Exp Lung Res (1992) 2.57

CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis. J Immunol (1999) 2.56

Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival. Infect Immun (1997) 2.54

An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J Immunol (1995) 2.52

Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumonia. J Immunol (1995) 2.51

Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8. J Exp Med (1991) 2.46

Idiopathic pulmonary fibrosis: predicting response to therapy and survival. Am J Respir Crit Care Med (1998) 2.43

Monokine-induced neutrophil chemotactic factor gene expression in human fibroblasts. J Biol Chem (1989) 2.43

Balance of inflammatory cytokines related to severity and mortality of murine sepsis. Infect Immun (1996) 2.43

Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J Clin Invest (1998) 2.42

The CXC chemokines, IL-8 and IP-10, regulate angiogenic activity in idiopathic pulmonary fibrosis. J Immunol (1997) 2.41

IL-4 inhibits the expression of IL-8 from stimulated human monocytes. J Immunol (1990) 2.41

Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome. J Clin Invest (2001) 2.39

Transhiatal esophagectomy without thoracotomy for carcinoma of the thoracic esophagus. Ann Surg (1984) 2.39

Cutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity. J Immunol (2001) 2.38

Protection from pulmonary fibrosis in the absence of CCR2 signaling. J Immunol (2001) 2.38

Prostaglandins as endogenous mediators of interleukin 1 production. J Immunol (1986) 2.37

The role of monocyte chemotactic protein-1 (MCP-1) in the recruitment of monocytes and CD4+ T cells during a pulmonary Cryptococcus neoformans infection. J Immunol (1995) 2.37

Staging of mediastinal non-small cell lung cancer with FDG PET, CT, and fusion images: preliminary prospective evaluation. Radiology (1994) 2.28

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene. Cell (1989) 2.27

IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense. J Immunol (1999) 2.25

Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells. Am J Pathol (1990) 2.25

Descending necrotizing mediastinitis: transcervical drainage is not enough. Ann Thorac Surg (1990) 2.24