Published in Cell on December 16, 1994
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50
A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol Cell Biol (1996) 5.75
Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. Proc Natl Acad Sci U S A (1995) 4.60
Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol Cell Biol (2001) 4.19
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol Cell Biol (1997) 4.11
Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage. Proc Natl Acad Sci U S A (1999) 3.68
The yeast Red1 protein localizes to the cores of meiotic chromosomes. J Cell Biol (1997) 3.07
Clarifying the mechanics of DNA strand exchange in meiotic recombination. Nature (2006) 3.02
Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57. Mol Cell Biol (1995) 2.96
Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes. Genes Dev (1998) 2.77
Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired. Genes Dev (2006) 2.68
Mammalian recombination hot spots: properties, control and evolution. Nat Rev Genet (2010) 2.54
Activities of human recombination protein Rad51. Proc Natl Acad Sci U S A (1997) 2.39
Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics (1997) 2.31
Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans. Chromosoma (2003) 2.29
Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin. Genes Dev (2006) 2.28
Tid1/Rdh54 promotes colocalization of rad51 and dmc1 during meiotic recombination. Proc Natl Acad Sci U S A (2000) 2.28
Random chromosome segregation without meiotic arrest in both male and female meiocytes of a dmc1 mutant of Arabidopsis. Plant Cell (1999) 2.27
DMC1 functions in a Saccharomyces cerevisiae meiotic pathway that is largely independent of the RAD51 pathway. Genetics (1997) 2.26
Meiotic cohesin REC8 marks the axial elements of rat synaptonemal complexes before cohesins SMC1beta and SMC3. J Cell Biol (2003) 2.23
Rad51 accumulation at sites of DNA damage and in postreplicative chromatin. J Cell Biol (2000) 2.22
ZMM proteins during meiosis: crossover artists at work. Chromosome Res (2007) 2.17
SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae. Genes Dev (2006) 2.16
From early homologue recognition to synaptonemal complex formation. Chromosoma (2006) 2.15
Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humans. Mol Cell Biol (1999) 2.09
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta (2007) 2.08
Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis. Proc Natl Acad Sci U S A (2001) 1.97
The Arabidopsis synaptonemal complex protein ZYP1 is required for chromosome synapsis and normal fidelity of crossing over. Genes Dev (2005) 1.96
Sex and the single cell: meiosis in yeast. Proc Natl Acad Sci U S A (1995) 1.94
Bdf1, a yeast chromosomal protein required for sporulation. Mol Cell Biol (1995) 1.92
The Arabidopsis AtRAD51 gene is dispensable for vegetative development but required for meiosis. Proc Natl Acad Sci U S A (2004) 1.85
A meiotic chromosomal core consisting of cohesin complex proteins recruits DNA recombination proteins and promotes synapsis in the absence of an axial element in mammalian meiotic cells. Mol Cell Biol (2001) 1.85
Distribution of the Rad51 recombinase in human and mouse spermatocytes. EMBO J (1997) 1.82
RAD51 and DMC1 form mixed complexes associated with mouse meiotic chromosome cores and synaptonemal complexes. J Cell Biol (1999) 1.81
Recombination activities of HsDmc1 protein, the meiotic human homolog of RecA protein. Proc Natl Acad Sci U S A (1997) 1.79
Association of fission yeast Orp1 and Mcm6 proteins with chromosomal replication origins. Mol Cell Biol (1999) 1.79
In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair. EMBO J (2004) 1.77
recA-like genes from three archaean species with putative protein products similar to Rad51 and Dmc1 proteins of the yeast Saccharomyces cerevisiae. Nucleic Acids Res (1996) 1.76
The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis. Nucleic Acids Res (1996) 1.75
Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes. Proc Natl Acad Sci U S A (1996) 1.74
ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis. Genes Dev (2007) 1.73
An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination. Mol Cell Biol (1997) 1.71
Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes. Am J Hum Genet (2004) 1.67
Meiotic double-strand breaks at the interface of chromosome movement, chromosome remodeling, and reductional division. Genes Dev (2003) 1.67
Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis. Genes Dev (2008) 1.66
Mek1 kinase activity functions downstream of RED1 in the regulation of meiotic double strand break repair in budding yeast. Mol Biol Cell (2003) 1.66
Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Genetics (1999) 1.61
Interchromosomal homology searches drive directional ALT telomere movement and synapsis. Cell (2014) 1.60
Localization and roles of Ski8p protein in Sordaria meiosis and delineation of three mechanistically distinct steps of meiotic homolog juxtaposition. Proc Natl Acad Sci U S A (2003) 1.60
RecA-like proteins are components of early meiotic nodules in lily. Proc Natl Acad Sci U S A (1997) 1.59
Three-dimensional microscopy of the Rad51 recombination protein during meiotic prophase. Plant Cell (1999) 1.57
Prelude to a division. Annu Rev Cell Dev Biol (2008) 1.55
Gradual implementation of the meiotic recombination program via checkpoint pathways controlled by global DSB levels. Mol Cell (2015) 1.54
The Mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair. Mol Cell Biol (2002) 1.52
Two distinct surveillance mechanisms monitor meiotic chromosome metabolism in budding yeast. Curr Biol (2006) 1.52
Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation. Mol Cell (2009) 1.51
Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis. Science (2012) 1.50
Presynaptic association of Rad51 protein with selected sites in meiotic chromatin. Proc Natl Acad Sci U S A (1996) 1.50
Rad51 expression and localization in B cells carrying out class switch recombination. Proc Natl Acad Sci U S A (1996) 1.50
Isolation and characterization of SYN1, a RAD21-like gene essential for meiosis in Arabidopsis. Plant Cell (1999) 1.48
Rad52 promotes postinvasion steps of meiotic double-strand-break repair. Mol Cell (2008) 1.47
Distribution of meiotic recombination events: talking to your neighbors. Curr Opin Genet Dev (2009) 1.46
Semidominant mutations in the yeast Rad51 protein and their relationships with the Srs2 helicase. Mol Cell Biol (1996) 1.45
Interaction of p53 with the human Rad51 protein. Nucleic Acids Res (1997) 1.43
Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1. PLoS Genet (2016) 1.41
Rad6-Bre1-mediated histone H2B ubiquitylation modulates the formation of double-strand breaks during meiosis. Proc Natl Acad Sci U S A (2004) 1.41
Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis. Mol Cell Biol (2007) 1.38
RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells. Nucleic Acids Res (2012) 1.36
Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1. EMBO J (2007) 1.33
The budding yeast mei5 and sae3 proteins act together with dmc1 during meiotic recombination. Genetics (2004) 1.33
Close, stable homolog juxtaposition during meiosis in budding yeast is dependent on meiotic recombination, occurs independently of synapsis, and is distinct from DSB-independent pairing contacts. Genes Dev (2002) 1.32
Quantitative time-lapse fluorescence microscopy in single cells. Annu Rev Cell Dev Biol (2009) 1.32
The interplay of RecA-related proteins and the MND1-HOP2 complex during meiosis in Arabidopsis thaliana. PLoS Genet (2007) 1.32
Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis. Genes Dev (1998) 1.31
Identification of the meiotic life cycle stage of Trypanosoma brucei in the tsetse fly. Proc Natl Acad Sci U S A (2011) 1.31
Multiple branches of the meiotic recombination pathway contribute independently to homolog pairing and stable juxtaposition during meiosis in budding yeast. Genes Dev (2005) 1.30
Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation. Proc Natl Acad Sci U S A (2004) 1.30
DNA-binding activities of Hop1 protein, a synaptonemal complex component from Saccharomyces cerevisiae. Mol Cell Biol (1998) 1.26
Csm4-dependent telomere movement on nuclear envelope promotes meiotic recombination. PLoS Genet (2008) 1.25
Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3. Genetics (1997) 1.25
Meiotic condensin is required for proper chromosome compaction, SC assembly, and resolution of recombination-dependent chromosome linkages. J Cell Biol (2003) 1.24
The diverse roles of transverse filaments of synaptonemal complexes in meiosis. Chromosoma (2006) 1.24
The many facets of SC function during C. elegans meiosis. Chromosoma (2006) 1.22
Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway. Nat Cell Biol (2010) 1.22
Evidence for a role for DNA polymerase beta in mammalian meiosis. Proc Natl Acad Sci U S A (1997) 1.22
TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint. Mol Biol Cell (2004) 1.21
Sufficient amounts of functional HOP2/MND1 complex promote interhomolog DNA repair but are dispensable for intersister DNA repair during meiosis in Arabidopsis. Plant Cell (2013) 1.21
Meiotic crossover control by concerted action of Rad51-Dmc1 in homolog template bias and robust homeostatic regulation. PLoS Genet (2013) 1.20
Dmc1 of Schizosaccharomyces pombe plays a role in meiotic recombination. Nucleic Acids Res (2000) 1.19
Altered nuclear distribution of recombination protein RAD51 in maize mutants suggests the involvement of RAD51 in meiotic homology recognition. Plant Cell (2003) 1.19
Meiotic recombination initiated by a double-strand break in rad50 delta yeast cells otherwise unable to initiate meiotic recombination. Genetics (1996) 1.19
Meiotic recombination-related DNA synthesis and its implications for cross-over and non-cross-over recombinant formation. Proc Natl Acad Sci U S A (2007) 1.18
Swi2/Snf2-related translocases prevent accumulation of toxic Rad51 complexes during mitotic growth. Mol Cell (2010) 1.17
A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint. Genes Dev (2002) 1.14
NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse. J Cell Sci (2007) 1.14
The Mei5-Sae3 protein complex mediates Dmc1 activity in Saccharomyces cerevisiae. J Biol Chem (2009) 1.13
Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycle. PLoS Genet (2011) 1.13
Meiotic recombination hotspots: shaping the genome and insights into hypervariable minisatellite DNA change. Curr Top Dev Biol (1998) 1.12
Meiosis genes in Daphnia pulex and the role of parthenogenesis in genome evolution. BMC Evol Biol (2009) 1.12