Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: role of glycosylation in the correct folding of the V1/V2 domain.

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Published in J Virol on April 01, 1995

Authors

Z Wu1, S C Kayman, W Honnen, K Revesz, H Chen, S Vijh-Warrier, S A Tilley, J McKeating, C Shotton, A Pinter

Author Affiliations

1: Public Health Research Institute, New York, New York 10016.

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Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Nature (2000) 1.85

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